DK142812B - Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf. Download PDF

Info

Publication number
DK142812B
DK142812B DK376577AA DK376577A DK142812B DK 142812 B DK142812 B DK 142812B DK 376577A A DK376577A A DK 376577AA DK 376577 A DK376577 A DK 376577A DK 142812 B DK142812 B DK 142812B
Authority
DK
Denmark
Prior art keywords
tetrahydro
indole
pyridyl
acid
addition salts
Prior art date
Application number
DK376577AA
Other languages
Danish (da)
English (en)
Other versions
DK142812C (ja
DK376577A (ja
Inventor
Lucien Nedelec
Jacques Guillaume
Claude Dumont
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK376577A publication Critical patent/DK376577A/da
Publication of DK142812B publication Critical patent/DK142812B/da
Application granted granted Critical
Publication of DK142812C publication Critical patent/DK142812C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DK376577AA 1976-08-26 1977-08-25 Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf. DK142812B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7625798A FR2362628A1 (fr) 1976-08-26 1976-08-26 Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR7625798 1976-08-26

Publications (3)

Publication Number Publication Date
DK376577A DK376577A (ja) 1978-02-27
DK142812B true DK142812B (da) 1981-02-02
DK142812C DK142812C (ja) 1981-09-21

Family

ID=9177152

Family Applications (1)

Application Number Title Priority Date Filing Date
DK376577AA DK142812B (da) 1976-08-26 1977-08-25 Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf.

Country Status (19)

Country Link
US (1) US4196209A (ja)
JP (1) JPS5328178A (ja)
AT (1) AT358582B (ja)
AU (1) AU510037B2 (ja)
BE (1) BE858101A (ja)
CA (1) CA1103676A (ja)
CH (2) CH624952A5 (ja)
DE (1) DE2738646C2 (ja)
DK (1) DK142812B (ja)
ES (1) ES461875A1 (ja)
FR (1) FR2362628A1 (ja)
GB (1) GB1556919A (ja)
HU (1) HU172711B (ja)
IE (1) IE45574B1 (ja)
LU (1) LU78028A1 (ja)
NL (1) NL7709383A (ja)
PT (1) PT66953B (ja)
SE (1) SE432595B (ja)
ZA (1) ZA775134B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152048B (da) * 1979-07-13 1988-01-25 Roussel Uclaf Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf.

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421899A1 (fr) * 1978-01-16 1979-11-02 Roussel Uclaf Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels
SE8004129L (sv) * 1979-07-13 1981-01-14 Roussel Uclaf Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar
DE3035403C2 (de) 1980-09-19 1982-08-26 Rütgerswerke AG, 6000 Frankfurt Verfahren zur Herstellung von 5-Chlorindol
FR2510111A1 (fr) * 1981-07-24 1983-01-28 Roussel Uclaf Nouveaux derives du piperidin-3-yl indole, leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
IE55972B1 (en) * 1982-10-07 1991-03-13 Kefalas As Phenylindene derivatives,acid addition salts thereof,and methods of preparation
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
FR2608157B1 (fr) * 1986-12-11 1989-09-08 Roussel Uclaf Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
PT88255B (pt) * 1987-08-13 1995-03-01 Glaxo Group Ltd Processo para a preparacao de derivados do indole
FR2621586B1 (fr) * 1987-10-08 1990-02-02 Roussel Uclaf Nouveaux derives de l'azapirodecane, leur procede de preparation et leur application comme medicaments
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
MX19185A (es) * 1989-01-20 1993-12-01 Pfizer Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas.
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
DK36291D0 (da) * 1991-03-01 1991-03-01 Lundbeck & Co As H Anvendelse af piperidylsubstituerede indolderivater til behandling af kognitive lidelser
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
EP1341777B1 (en) * 2000-11-29 2007-09-26 Eli Lilly And Company 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatement of incontinence
WO2004069828A1 (ja) * 2003-02-04 2004-08-19 Mitsubishi Pharma Corporation ピペリジン化合物およびその医薬用途
JP2009515833A (ja) * 2005-10-24 2009-04-16 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ３−ピペリジン−４−イル−インドールｏｒｌ−１受容体モジュレーター

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872453A (en) * 1959-02-03 Indole derivatives
US3361759A (en) * 1963-10-07 1968-01-02 Upjohn Co 3-(2-pyrrolidinyl)-indoles and method of preparation
JPS4856687A (ja) * 1971-11-18 1973-08-09
FR2193584B1 (ja) * 1972-07-28 1975-08-08 Roussel Uclaf
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2258843B1 (ja) * 1974-01-30 1977-09-09 Roussel Uclaf
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
FR2349331A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152048B (da) * 1979-07-13 1988-01-25 Roussel Uclaf Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf.

Also Published As

Publication number Publication date
CH624952A5 (ja) 1981-08-31
GB1556919A (en) 1979-11-28
BE858101A (fr) 1978-02-27
CA1103676A (fr) 1981-06-23
ZA775134B (en) 1978-09-27
FR2362628B1 (ja) 1979-03-02
FR2362628A1 (fr) 1978-03-24
CH628344A5 (fr) 1982-02-26
DK142812C (ja) 1981-09-21
NL7709383A (nl) 1978-02-28
AT358582B (de) 1980-09-25
SE432595B (sv) 1984-04-09
IE45574B1 (en) 1982-10-06
LU78028A1 (ja) 1978-04-27
JPS631312B2 (ja) 1988-01-12
PT66953A (fr) 1977-09-01
IE45574L (en) 1978-02-26
AU2821377A (en) 1979-03-01
DK376577A (ja) 1978-02-27
DE2738646C2 (de) 1985-08-08
US4196209A (en) 1980-04-01
ATA619677A (de) 1980-02-15
DE2738646A1 (de) 1978-03-02
PT66953B (fr) 1979-11-12
ES461875A1 (es) 1978-05-16
HU172711B (hu) 1978-11-28
AU510037B2 (en) 1980-06-05
JPS5328178A (en) 1978-03-16
SE7707731L (sv) 1978-02-27

Similar Documents

Publication Publication Date Title
DK142812B (da) Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf.
AU2018236805C1 (en) Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
DK148477B (da) Analogifremgangsmaade til fremstilling af tetrahydropyridinylindolderivater eller additionssalte deraf
JPS6155907B2 (ja)
JPS61183223A (ja) アリールアミドアザビシクロアルカンを含む記憶増強または記憶欠損矯正用組成物
JPS59501409A (ja) ピリドン化合物
BG61120B2 (bg) Производни на 1,2,5,6-тетрахидропиридин-3-карбоксалдехид оксим,метод за получаването им,приложението им като лекарствени средства и съдържащите ги състави
EP3046905A1 (en) Vinyl autotaxin inhibitor compounds
WO2015042052A1 (en) Heterocyclic vinyl autotaxin inhibitor compounds
DK149773B (da) Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater
NO158871B (no) Analogifremgangsmaate for fremstilling av pyridazinderivater.
UA120389C2 (uk) Нові сполуки піридинію
JP2018502075A (ja) 抗ヒスタミン剤としての新規ベンゾイミダゾール誘導体
EP0000108B1 (fr) Benzo(b)thiéno-pyridines, leur procédé de préparation et composition thérapeutique les contenant
DK152048B (da) Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf.
KR100437561B1 (ko) 신규헤테로고리화합물
CH635587A5 (fr) Derives amines de pyrazolo (1,5-a) s.triazine, therapeutiquement actifs et leurs procedes de preparation.
WO2016144706A2 (en) Autotaxin inhibitor compounds and uses thereof
JPS58103377A (ja) ２−フエニル−モルホリン誘導体およびこの化合物を含有する抗うつ剤
CH642963A5 (fr) Procede de preparation de derives du piperidyl-indole, 5-nitro 3-(1,2,3,6-tetrahydro pyridin-4-yl) 1h-indole et ses sels et medicament les renfermant.
NO164498B (no) Spenneanordning.
US4104385A (en) Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates
CZ278281B6 (en) ENOL ETHER OF 1,1-DIOXIDE OF 6-CHLORO-4-HYDROXY-2-METHYL-N- (2-PYRIDYL-2H-THIENO(2,3-c)-1,2-THIAZINECARBOXYLIC ACID AMIDE, PROCESS OF ITS PREPARATION AND ITS USE
US3937830A (en) 5-pivaloyloxy-5-(1-phenylethyl) barbituric acid, analgetic composition and method based thereon
RU2068415C1 (ru) 5,7-диокси-2-метил-8-/4-(3-окси-1-(1-пропил)пиперидинил/-4н-1-бензопиран-4-он или его стереоизомеры или фармакологически приемлемые кислотно-аддитивные соли и способ их получения

Legal Events

Date Code Title Description
PBP Patent lapsed