DK141603C - - Google Patents

Info

Publication number
DK141603C
DK141603C DK2773A DK2773A DK141603C DK 141603 C DK141603 C DK 141603C DK 2773 A DK2773 A DK 2773A DK 2773 A DK2773 A DK 2773A DK 141603 C DK141603 C DK 141603C
Authority
DK
Denmark
Application number
DK2773A
Other languages
Danish (da)
Other versions
DK141603B (da
Inventor
K Nakagawa
N Murakami
S Yoshizaki
H Mori
M Tominaga
Y Tamura
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47092560A external-priority patent/JPS5246231B2/ja
Priority claimed from JP9255772A external-priority patent/JPS5324431B2/ja
Priority claimed from JP47092558A external-priority patent/JPS5241268B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to DK138076A priority Critical patent/DK152492C/da
Priority to DK137976A priority patent/DK137976A/da
Publication of DK141603B publication Critical patent/DK141603B/da
Application granted granted Critical
Publication of DK141603C publication Critical patent/DK141603C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK2773AA 1972-04-13 1973-01-03 Analogifremgangsmåde til fremstilling af 3,4-dihydrocarbostyril-derivater. DK141603B (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK138076A DK152492C (da) 1972-04-13 1976-03-29 3,4-dihydrocarbostyril-derivater til anvendelse som mellemprodukter til fremstilling af biologisk aktive 3,4-dihydrocarbostyril-derivater
DK137976A DK137976A (da) 1972-04-13 1976-03-29 Fremgangsmade til fremstilling af 2,4-dihydrocarbostyril-derivater

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
JP3718172 1972-04-13
JP3718272 1972-04-13
JP47037181A JPS517672B2 (ja) 1972-04-13 1972-04-13
JP47037182A JPS48103590A (ja) 1972-04-13 1972-04-13
JP9256072 1972-09-14
JP47092560A JPS5246231B2 (ja) 1972-09-14 1972-09-14
JP9255772 1972-09-14
JP9255772A JPS5324431B2 (ja) 1972-09-14 1972-09-14
JP47092558A JPS5241268B2 (ja) 1972-09-14 1972-09-14
JP9255872 1972-09-14
JP47120953A JPS5229745B2 (ja) 1972-04-13 1972-12-02
JP12095372 1972-12-02
JP12585872 1972-12-14
JP47125858A JPS5239036B2 (ja) 1972-04-13 1972-12-14
JP47128972A JPS5241269B2 (ja) 1972-04-13 1972-12-21
JP12897272 1972-12-21

Publications (2)

Publication Number Publication Date
DK141603B DK141603B (da) 1980-05-05
DK141603C true DK141603C (ja) 1980-10-06

Family

ID=27572212

Family Applications (1)

Application Number Title Priority Date Filing Date
DK2773AA DK141603B (da) 1972-04-13 1973-01-03 Analogifremgangsmåde til fremstilling af 3,4-dihydrocarbostyril-derivater.

Country Status (17)

Country Link
JP (5) JPS517672B2 (ja)
AR (1) AR209575A1 (ja)
AU (1) AU475964B2 (ja)
BE (1) BE794669A (ja)
CA (1) CA1025447A (ja)
CH (1) CH575929A5 (ja)
DD (2) DD112446A5 (ja)
DE (1) DE2302027C2 (ja)
DK (1) DK141603B (ja)
FI (1) FI53703C (ja)
FR (1) FR2179715B1 (ja)
GB (2) GB1424572A (ja)
HK (1) HK19481A (ja)
NL (1) NL158176B (ja)
NO (1) NO140589C (ja)
SE (1) SE380018B (ja)
YU (1) YU41187B (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5082218A (ja) * 1973-11-10 1975-07-03
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4137331A (en) 1974-06-19 1979-01-30 Sandoz Ltd. 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones
JPS516971A (en) * 1974-07-08 1976-01-20 Otsuka Pharma Co Ltd Nitoro 3*44 jihidorokarubosuchirirujudotaino seizoho
JPS5129486A (en) * 1974-09-02 1976-03-12 Otsuka Pharma Co Ltd * 33 arukiruamino 22 hidorokishi * purohokishi 3 44 jihidorokarubosuchirirujudotai no seizoho
JPS5148674A (en) * 1974-10-17 1976-04-26 Otsuka Pharma Co Ltd 3 44 jihidorokarubosuchirirujudotaino seizoho
JPS5152180A (ja) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
JPS5152179A (ja) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
JPS5152178A (ja) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH619453A5 (ja) * 1976-03-17 1980-09-30 Otsuka Pharma Co Ltd
DE2719562C2 (de) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2960178D1 (en) * 1978-06-06 1981-04-09 Hoechst Ag New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
DE2827566A1 (de) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS58103343A (ja) * 1981-12-15 1983-06-20 Ota Seiyaku Kk プロパノ−ルアミン化合物の製造法
JPS597186A (ja) * 1982-07-02 1984-01-14 Ota Seiyaku Kk １，３，２−ジオキサチオラン２−オキシド誘導体
JPS63193086U (ja) * 1987-05-30 1988-12-13
DE3808136A1 (de) * 1988-03-11 1989-09-21 Thomae Gmbh Dr K Arzneimittel, enthaltend chinolin-2,5-dione, neue chinolin-2,5-dione und verfahren zu ihrer herstellung
DK391189A (da) * 1988-08-10 1990-02-11 Otsuka Pharma Co Ltd Carbostyrilderivater
US5266577A (en) * 1988-08-10 1993-11-30 Otsuka Pharmaceutical Company Ltd. Method of treating congestive heart failure using carbostyril derivatives
WO1993004042A1 (fr) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Derive de carbostyrile et antiagregant plaquettaire
ES2048108B1 (es) * 1992-07-17 1994-10-01 Lusochimica Spa Procedimiento para la preparacion de 5-(3-terc-butilamino-2-hidroxipropoxi)-3,4-dihidrocarboestirilo.
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
CZ300351B6 (cs) * 2005-05-26 2009-04-29 Zentiva, A. S. Zpusob prípravy 7-hydroxy-3,4-dihydrokarbostyrilu

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
CH523899A (de) * 1968-07-05 1972-06-15 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 2-Oxo-1,2-dihydro-chinolins

Also Published As

Publication number Publication date
FR2179715B1 (ja) 1976-12-03
AU475964B2 (en) 1976-09-09
BE794669A (fr) 1973-05-16
GB1424571A (en) 1976-02-11
JPS4976878A (ja) 1974-07-24
JPS48103589A (ja) 1973-12-25
SE380018B (ja) 1975-10-27
GB1424572A (en) 1976-02-11
DE2302027A1 (de) 1973-12-06
JPS48103590A (ja) 1973-12-25
JPS5241269B2 (ja) 1977-10-17
JPS517672B2 (ja) 1976-03-10
CA1025447A (en) 1978-01-31
FR2179715A1 (ja) 1973-11-23
NL7302353A (ja) 1973-10-16
YU41187B (en) 1986-12-31
DD108293A5 (ja) 1974-09-12
JPS5229745B2 (ja) 1977-08-03
JPS4982673A (ja) 1974-08-08
NO140589B (no) 1979-06-25
HK19481A (en) 1981-05-22
AU5438673A (en) 1974-10-17
NL158176B (nl) 1978-10-16
JPS4981373A (ja) 1974-08-06
DE2302027C2 (de) 1983-03-17
YU254979A (en) 1982-10-31
FI53703B (ja) 1978-03-31
JPS5239036B2 (ja) 1977-10-03
AR209575A1 (es) 1977-05-13
DD112446A5 (ja) 1975-04-12
DK141603B (da) 1980-05-05
FI53703C (fi) 1978-07-10
NO140589C (no) 1979-10-03
CH575929A5 (ja) 1976-05-31

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Legal Events

Date Code Title Description
PUP Patent expired
CTFF Application for supplementary protection certificate (spc) filed

Spc suppl protection certif: CA 1993 00001

Filing date: 19930102

CTFF Application for supplementary protection certificate (spc) filed

Spc suppl protection certif: CA 1993 00001

Filing date: 19930102