DK391189A - Carbostyrilderivater - Google Patents
Carbostyrilderivater Download PDFInfo
- Publication number
- DK391189A DK391189A DK391189A DK391189A DK391189A DK 391189 A DK391189 A DK 391189A DK 391189 A DK391189 A DK 391189A DK 391189 A DK391189 A DK 391189A DK 391189 A DK391189 A DK 391189A
- Authority
- DK
- Denmark
- Prior art keywords
- carbostyril derivatives
- carbostyril
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20092988 | 1988-08-10 | ||
JP3468889 | 1989-02-14 | ||
JP16017089 | 1989-06-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK391189D0 DK391189D0 (da) | 1989-08-09 |
DK391189A true DK391189A (da) | 1990-02-11 |
Family
ID=27288505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK391189A DK391189A (da) | 1988-08-10 | 1989-08-09 | Carbostyrilderivater |
Country Status (7)
Country | Link |
---|---|
US (2) | US5053514A (da) |
EP (1) | EP0355583B1 (da) |
JP (1) | JP2648970B2 (da) |
KR (1) | KR0139626B1 (da) |
DE (1) | DE68920797T2 (da) |
DK (1) | DK391189A (da) |
ES (1) | ES2070151T3 (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5198448A (en) * | 1988-08-10 | 1993-03-30 | Otsuka Pharmaceutical Company, Limited | Cardiotonics |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
TW201305B (da) * | 1991-04-03 | 1993-03-01 | Otsuka Pharma Co Ltd | |
KR930702307A (ko) * | 1991-08-23 | 1993-09-08 | 오오쓰까 아끼히꼬 | 카르보스티릴 유도체 및 혈소판 응집 억제제 |
DE69316018T2 (de) * | 1992-09-18 | 1998-04-16 | Otsuka Pharma Co Ltd | Carbostyrilderivate als antiarrhytmika |
JPH06183976A (ja) * | 1992-09-18 | 1994-07-05 | Otsuka Pharmaceut Co Ltd | 抗不整脈剤 |
TW254855B (da) * | 1993-07-28 | 1995-08-21 | Otsuka Pharma Co Ltd | |
US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
KR19980701286A (ko) * | 1995-01-09 | 1998-05-15 | 오스카 아키히코 | Tnf-알파 억제제 |
US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
DE69733649T2 (de) | 1996-04-09 | 2006-05-18 | NPS Pharmaceuticals, Inc., Salt Lake City | Calcylitische verbindungen |
US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
TW483881B (en) | 1996-12-03 | 2002-04-21 | Nps Pharma Inc | Calcilytic compounds |
SK3902000A3 (en) * | 1997-09-24 | 2000-12-11 | Orion Corp | Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors |
HU227441B1 (en) † | 1997-11-24 | 2011-06-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Process for producing carvedilol, enantiomers and salts thereof |
US7053092B2 (en) * | 2001-01-29 | 2006-05-30 | Otsuka Pharmaceutical Co., Ltd. | 5-HT1a receptor subtype agonist |
AR033485A1 (es) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
US8703772B2 (en) | 2001-09-25 | 2014-04-22 | Otsuka Pharmaceutical Co., Ltd. | Low hygroscopic aripiprazole drug substance and processes for the preparation thereof |
MXPA05005661A (es) * | 2002-11-27 | 2005-11-23 | Artesian Therapeutics Inc | Compuestos con actividad antagonista o antagonista parcial mixta inhibidora de fosfodiesterasa y beta-adrenergica para el tratamiento de insuficiencia cardiaca. |
AU2003300297A1 (en) * | 2002-12-23 | 2004-07-22 | Artesian Therapeutics, Inc. | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST Beta-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE |
TWI481601B (zh) * | 2009-08-21 | 2015-04-21 | Otsuka Pharma Co Ltd | 含氮化合物及藥學組成物 |
KR102015054B1 (ko) * | 2015-08-10 | 2019-08-27 | 동우 화인켐 주식회사 | 네가티브형 감광성 수지 조성물 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
JPS48103590A (da) * | 1972-04-13 | 1973-12-25 | ||
JPS4951271A (da) * | 1972-09-28 | 1974-05-18 | ||
JPS5241270B2 (da) * | 1973-01-25 | 1977-10-17 | ||
JPS5082218A (da) * | 1973-11-10 | 1975-07-03 | ||
JPS539227B2 (da) * | 1973-12-26 | 1978-04-04 | ||
US4210753A (en) * | 1976-03-17 | 1980-07-01 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril compounds |
DE2805404A1 (de) * | 1978-02-09 | 1979-08-16 | Merck Patent Gmbh | 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung |
JPS54151985A (en) * | 1978-05-17 | 1979-11-29 | Otsuka Pharmaceut Co Ltd | Preparation of aminocarbostyril derivative |
AU518814B2 (en) * | 1979-01-30 | 1981-10-22 | Otsuka Pharamaceutical Co. | Glaucoma treatment |
DD150456A5 (de) * | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols |
JPS55129268A (en) * | 1979-03-28 | 1980-10-06 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS5695115A (en) * | 1979-12-28 | 1981-08-01 | Otsuka Pharmaceut Co Ltd | Remedy for glaucoma |
JPS568319A (en) * | 1980-03-26 | 1981-01-28 | Otsuka Pharmaceut Co Ltd | Antihistamine |
JPS5780322A (en) * | 1980-11-05 | 1982-05-19 | Otsuka Pharmaceut Co Ltd | Cardiotonic agent |
DE3330005A1 (de) * | 1983-08-19 | 1985-02-28 | Wolfgang Dr. Graz Lindner | Weinsaeuremonoester von optisch aktiven alkanolaminen, verfahren zu ihrer herstellung und ihre verwendung |
GB2163150B (en) * | 1984-07-19 | 1988-05-25 | Sandoz Ltd | 3-aminopropoxyaryl derivatives |
DK397387A (da) * | 1986-07-31 | 1988-02-01 | Otsuka Pharma Co Ltd | Carbostyrilderivater og salte deraf samt fremgangsmaade til fremstilling af saadanne forbindelser |
-
1989
- 1989-08-09 DK DK391189A patent/DK391189A/da not_active Application Discontinuation
- 1989-08-09 EP EP89114712A patent/EP0355583B1/en not_active Expired - Lifetime
- 1989-08-09 US US07/391,305 patent/US5053514A/en not_active Expired - Lifetime
- 1989-08-09 DE DE68920797T patent/DE68920797T2/de not_active Expired - Fee Related
- 1989-08-09 ES ES89114712T patent/ES2070151T3/es not_active Expired - Lifetime
- 1989-08-10 JP JP1208725A patent/JP2648970B2/ja not_active Expired - Fee Related
- 1989-08-10 KR KR1019890011477A patent/KR0139626B1/ko not_active IP Right Cessation
-
1993
- 1993-11-12 US US08/150,792 patent/US5385914A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK391189D0 (da) | 1989-08-09 |
US5385914A (en) | 1995-01-31 |
DE68920797D1 (de) | 1995-03-09 |
DE68920797T2 (de) | 1995-06-29 |
ES2070151T3 (es) | 1995-06-01 |
EP0355583A3 (en) | 1991-11-06 |
KR0139626B1 (ko) | 1998-06-01 |
JP2648970B2 (ja) | 1997-09-03 |
JPH0386864A (ja) | 1991-04-11 |
EP0355583A2 (en) | 1990-02-28 |
US5053514A (en) | 1991-10-01 |
EP0355583B1 (en) | 1995-01-25 |
KR900003127A (ko) | 1990-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |