DK1404872T3 - Fremgangsmåde til selektion af en DNA-sekvens med transkriptionsmodulerende aktivitet med en vektor indeholdende et element med en gentranskriptionsundertrykkende aktivitet - Google Patents

Fremgangsmåde til selektion af en DNA-sekvens med transkriptionsmodulerende aktivitet med en vektor indeholdende et element med en gentranskriptionsundertrykkende aktivitet

Info

Publication number
DK1404872T3
DK1404872T3 DK02741531T DK02741531T DK1404872T3 DK 1404872 T3 DK1404872 T3 DK 1404872T3 DK 02741531 T DK02741531 T DK 02741531T DK 02741531 T DK02741531 T DK 02741531T DK 1404872 T3 DK1404872 T3 DK 1404872T3
Authority
DK
Denmark
Prior art keywords
transcriptional
activity
selecting
dna sequence
vector containing
Prior art date
Application number
DK02741531T
Other languages
Danish (da)
English (en)
Inventor
Arie Pieter Otte
Arthur Leo Kruckeberg
Original Assignee
Chromagenics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP01202581A external-priority patent/EP1273666A1/fr
Application filed by Chromagenics Bv filed Critical Chromagenics Bv
Application granted granted Critical
Publication of DK1404872T3 publication Critical patent/DK1404872T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK02741531T 2001-07-04 2002-06-14 Fremgangsmåde til selektion af en DNA-sekvens med transkriptionsmodulerende aktivitet med en vektor indeholdende et element med en gentranskriptionsundertrykkende aktivitet DK1404872T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP01202581A EP1273666A1 (fr) 2001-07-04 2001-07-04 Procédé de séléction d'une séquence d'ADN avec une activité de modulation de la transcription utilisant un vecteur comportant un élement a activité transcripto-répréssive
US30319901P 2001-07-05 2001-07-05
PCT/NL2002/000390 WO2003004704A2 (fr) 2001-07-04 2002-06-14 Sequences d'adn comprenant des qualites de regulation de la transcription genique et methodes de detection et d'utilisation de ces sequences d'adn
US10/190,312 US7192741B2 (en) 2001-07-04 2002-07-05 DNA sequences comprising gene transcription regulatory qualities and methods for detecting and using such DNA sequences

Publications (1)

Publication Number Publication Date
DK1404872T3 true DK1404872T3 (da) 2007-02-19

Family

ID=47915807

Family Applications (8)

Application Number Title Priority Date Filing Date
DK06124491.9T DK1842919T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med antirepressoraktivitet
DK05076209T DK1600510T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med antirepressoraktivitet
DK06124465.3T DK1808488T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet
DK02741531T DK1404872T3 (da) 2001-07-04 2002-06-14 Fremgangsmåde til selektion af en DNA-sekvens med transkriptionsmodulerende aktivitet med en vektor indeholdende et element med en gentranskriptionsundertrykkende aktivitet
DK06124475.2T DK1829971T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet
DK06124482.8T DK1829972T3 (da) 2001-07-04 2002-06-14 DNA-Sekvenser med anti-repressoraktivitet
DK06124470.3T DK1806407T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet
DK06124481.0T DK1845162T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DK06124491.9T DK1842919T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med antirepressoraktivitet
DK05076209T DK1600510T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med antirepressoraktivitet
DK06124465.3T DK1808488T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet

Family Applications After (4)

Application Number Title Priority Date Filing Date
DK06124475.2T DK1829971T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet
DK06124482.8T DK1829972T3 (da) 2001-07-04 2002-06-14 DNA-Sekvenser med anti-repressoraktivitet
DK06124470.3T DK1806407T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet
DK06124481.0T DK1845162T3 (da) 2001-07-04 2002-06-14 DNA-sekvenser med anti-repressoraktivitet

Country Status (22)

Country Link
US (9) US7192741B2 (fr)
EP (8) EP1829971B1 (fr)
JP (3) JP4500044B2 (fr)
KR (2) KR100942117B1 (fr)
CN (1) CN1266282C (fr)
AT (8) ATE466941T1 (fr)
AU (3) AU2002314629B2 (fr)
BR (1) BRPI0210771B8 (fr)
CA (2) CA2450020C (fr)
CY (1) CY1107678T1 (fr)
DE (8) DE60236333D1 (fr)
DK (8) DK1842919T3 (fr)
ES (8) ES2344071T3 (fr)
HK (1) HK1068652A1 (fr)
IL (4) IL159674A0 (fr)
MX (1) MXPA03011801A (fr)
NO (1) NO338477B1 (fr)
NZ (1) NZ530218A (fr)
PT (1) PT1600510E (fr)
SG (1) SG143066A1 (fr)
WO (1) WO2003004704A2 (fr)
ZA (1) ZA200309599B (fr)

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WO2003106674A2 (fr) 2002-06-14 2003-12-24 Chromagenics B.V. Moyens et procedes de regulation de l'expression genique
DK1573058T3 (da) 2002-12-18 2012-01-16 Chromagenics Bv Fremgangsmåde til forbedring af proteinproduktion
EP1572994B1 (fr) 2002-12-20 2007-02-21 Chromagenics B.V. Moyens et methodes pour la production d'une proteine par des ouvre-chromatine capable de rendre le chromatine plus accessible aux facteurs de transcription

Also Published As

Publication number Publication date
IL159674A0 (en) 2004-06-20
US7736868B2 (en) 2010-06-15
ATE358183T1 (de) 2007-04-15
US7749733B2 (en) 2010-07-06
EP1600510A2 (fr) 2005-11-30
JP4500044B2 (ja) 2010-07-14
KR100942117B1 (ko) 2010-02-12
NO20040011L (no) 2004-03-03
CN1524128A (zh) 2004-08-25
EP1600510A3 (fr) 2006-02-22
DE60236331D1 (de) 2010-06-17
EP1808488A2 (fr) 2007-07-18
US7736870B2 (en) 2010-06-15
AU2002314629B2 (en) 2007-08-30
US20070026498A1 (en) 2007-02-01
ES2344073T3 (es) 2010-08-17
JP5014444B2 (ja) 2012-08-29
DE60236379D1 (de) 2010-06-24
US7659094B2 (en) 2010-02-09
JP2010131025A (ja) 2010-06-17
DE60215502T2 (de) 2007-08-30
KR20090037960A (ko) 2009-04-16
DE60219221T2 (de) 2008-01-03
EP1829972B1 (fr) 2010-05-12
BR0210771A (pt) 2004-07-13
IL193373A (en) 2010-12-30
NO338477B1 (no) 2016-08-22
ES2344070T3 (es) 2010-08-17
CA2812799A1 (fr) 2003-01-16
US20070031934A1 (en) 2007-02-08
NZ530218A (en) 2005-09-30
DE60236334D1 (de) 2010-06-17
US7736869B2 (en) 2010-06-15
KR100942116B1 (ko) 2010-02-12
ES2344072T3 (es) 2010-08-17
EP1829972A3 (fr) 2007-10-24
BRPI0210771B1 (pt) 2015-12-22
DK1806407T3 (da) 2010-08-16
DE60215502D1 (de) 2006-11-30
JP5014443B2 (ja) 2012-08-29
US20030199468A1 (en) 2003-10-23
DK1600510T3 (da) 2007-06-25
HK1068652A1 (en) 2005-04-29
DK1842919T3 (da) 2010-08-16
ATE466943T1 (de) 2010-05-15
ES2348174T3 (es) 2010-11-30
ES2285630T3 (es) 2007-11-16
EP1829971A1 (fr) 2007-09-05
US20070037256A1 (en) 2007-02-15
IL193374A (en) 2010-12-30
ATE467682T1 (de) 2010-05-15
US7192741B2 (en) 2007-03-20
DE60237048D1 (de) 2010-08-26
IL159674A (en) 2009-02-11
EP1842919A1 (fr) 2007-10-10
CA2450020A1 (fr) 2003-01-16
US7951586B2 (en) 2011-05-31
EP1600510B1 (fr) 2007-03-28
SG143066A1 (en) 2008-06-27
DE60219221D1 (de) 2007-05-10
JP2004533262A (ja) 2004-11-04
EP1806407A2 (fr) 2007-07-11
EP1829971B1 (fr) 2010-05-05
ES2274045T3 (es) 2007-05-16
WO2003004704A2 (fr) 2003-01-16
EP1806407B1 (fr) 2010-05-05
EP1829971A3 (fr) 2008-06-04
AU2007234619A1 (en) 2007-12-13
ATE343004T1 (de) 2006-11-15
DE60236333D1 (de) 2010-06-17
MXPA03011801A (es) 2005-03-07
AU2007234619B2 (en) 2011-06-02
US20070031936A1 (en) 2007-02-08
EP1806407A3 (fr) 2008-06-04
CN1266282C (zh) 2006-07-26
ES2344071T3 (es) 2010-08-17
ES2344074T3 (es) 2010-08-17
DE60236332D1 (de) 2010-06-17
EP1829972A2 (fr) 2007-09-05
CA2450020C (fr) 2013-08-13
US20070026499A1 (en) 2007-02-01
PT1600510E (pt) 2007-06-25
AU2011202193B2 (en) 2011-09-29
JP2010131024A (ja) 2010-06-17
DK1829972T3 (da) 2010-09-13
KR20090037485A (ko) 2009-04-15
DK1829971T3 (da) 2010-08-16
EP1404872A2 (fr) 2004-04-07
EP1404872B1 (fr) 2006-10-18
CY1107678T1 (el) 2013-04-18
US7655441B2 (en) 2010-02-02
WO2003004704A3 (fr) 2003-10-16
ATE466941T1 (de) 2010-05-15
US20070031933A1 (en) 2007-02-08
EP1845162B1 (fr) 2010-05-05
EP1808488A3 (fr) 2007-11-14
EP1842919B1 (fr) 2010-05-05
ATE466942T1 (de) 2010-05-15
US20070031935A1 (en) 2007-02-08
EP1845162A1 (fr) 2007-10-17
DK1845162T3 (da) 2010-08-16
ZA200309599B (en) 2006-05-31
BRPI0210771B8 (pt) 2021-05-25
EP1808488B1 (fr) 2010-07-14
US7662591B2 (en) 2010-02-16
ATE474053T1 (de) 2010-07-15
AU2011202193A1 (en) 2011-06-02
US20070128717A1 (en) 2007-06-07
CA2812799C (fr) 2016-01-26
ATE466944T1 (de) 2010-05-15
DK1808488T3 (da) 2010-10-18

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