ZA200309599B - Method of selecting DNA sequence with transcription modulating activity using a vector comprising an element with a gene transcription representing activity - Google Patents
Method of selecting DNA sequence with transcription modulating activity using a vector comprising an element with a gene transcription representing activity Download PDFInfo
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202581A EP1273666A1 (fr) | 2001-07-04 | 2001-07-04 | Procédé de séléction d'une séquence d'ADN avec une activité de modulation de la transcription utilisant un vecteur comportant un élement a activité transcripto-répréssive |
| US30319901P | 2001-07-05 | 2001-07-05 | |
| US10/190,312 US7192741B2 (en) | 2001-07-04 | 2002-07-05 | DNA sequences comprising gene transcription regulatory qualities and methods for detecting and using such DNA sequences |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200309599B true ZA200309599B (en) | 2006-05-31 |
Family
ID=47915807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200309599A ZA200309599B (en) | 2001-07-04 | 2003-12-10 | Method of selecting DNA sequence with transcription modulating activity using a vector comprising an element with a gene transcription representing activity |
Country Status (22)
| Country | Link |
|---|---|
| US (9) | US7192741B2 (fr) |
| EP (8) | EP1829971B1 (fr) |
| JP (3) | JP4500044B2 (fr) |
| KR (2) | KR100942117B1 (fr) |
| CN (1) | CN1266282C (fr) |
| AT (8) | ATE358183T1 (fr) |
| AU (3) | AU2002314629B2 (fr) |
| BR (1) | BRPI0210771B8 (fr) |
| CA (2) | CA2450020C (fr) |
| CY (1) | CY1107678T1 (fr) |
| DE (8) | DE60236331D1 (fr) |
| DK (8) | DK1829972T3 (fr) |
| ES (8) | ES2344070T3 (fr) |
| HK (1) | HK1068652A1 (fr) |
| IL (4) | IL159674A0 (fr) |
| MX (1) | MXPA03011801A (fr) |
| NO (1) | NO338477B1 (fr) |
| NZ (1) | NZ530218A (fr) |
| PT (1) | PT1600510E (fr) |
| SG (1) | SG143066A1 (fr) |
| WO (1) | WO2003004704A2 (fr) |
| ZA (1) | ZA200309599B (fr) |
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| EP1513936A2 (fr) | 2002-06-14 | 2005-03-16 | Chromagenics B.V. | Utilisation de sequences de blocage de repression pour ameliorer l'expression d e genes |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| CA2965865C (fr) | 2002-07-18 | 2021-10-19 | Merus N.V. | Production par recombinaison de melanges d'anticorps |
| WO2004055215A1 (fr) | 2002-12-18 | 2004-07-01 | Chromagenics B.V. | Procede d'amelioration de production de proteines |
| EP1572994B1 (fr) | 2002-12-20 | 2007-02-21 | Chromagenics B.V. | Moyens et methodes pour la production d'une proteine par des ouvre-chromatine capable de rendre le chromatine plus accessible aux facteurs de transcription |
| EP2395016A3 (fr) | 2003-05-30 | 2012-12-19 | Merus B.V. | Conception et utilisation de régions variables appariées de molécules de liaison spécifiques |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| JP4749334B2 (ja) | 2003-10-02 | 2011-08-17 | クルセル ホランド ベー ヴェー | 組換えアデノウイルス用パッケージング細胞 |
| WO2005059149A2 (fr) * | 2003-12-12 | 2005-06-30 | Chromagenics B.V. | Fabrication amelioree de proteines |
| DK1737971T3 (da) | 2004-01-20 | 2017-11-13 | Merus Nv | Blandinger af bindingsproteiner |
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| US8039230B2 (en) | 2004-11-08 | 2011-10-18 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| US8999667B2 (en) | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| JP5291341B2 (ja) * | 2004-11-08 | 2013-09-18 | クロマジェニックス ベー ヴェー | タンパク質を高レベルで発現する宿主細胞の選定 |
| SI1809750T1 (sl) * | 2004-11-08 | 2012-08-31 | Chromagenics Bv | Izbira gostiteljskih celic, ki imajo visok nivo izraĹľanja proteina |
| KR100984602B1 (ko) * | 2004-11-18 | 2010-09-30 | 고쿠리츠다이가쿠호진 히로시마다이가쿠 | 유전자 증폭에 의해 형성된 반복서열로부터, 발현이 억제된단백질을 발현시키는 방법, 키트, 및 형질전환체 |
| EP1996705B1 (fr) | 2006-03-20 | 2011-08-31 | ChromaGenics B.V. | Système d'expression permettant d'augmenter des fragments d'adn, son utilisation, et procédés permettant de le trouver |
| US20080124760A1 (en) | 2006-07-26 | 2008-05-29 | Barbara Enenkel | Regulatory Nucleic Acid Elements |
| JP2010515435A (ja) * | 2007-01-08 | 2010-05-13 | ミリポア・コーポレイション | 遺伝子増幅を不要とする高発現細胞株 |
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| AU2013249985B2 (en) | 2012-04-20 | 2017-11-23 | Merus N.V. | Methods and means for the production of Ig-like molecules |
| SG11201408646VA (en) | 2012-07-06 | 2015-01-29 | Genmab Bv | Dimeric protein with triple mutations |
| ES2692951T3 (es) | 2012-09-27 | 2018-12-05 | Merus N.V. | Anticuerpos IgG biespecíficos como acopladores de células T |
| US10417380B1 (en) | 2013-12-31 | 2019-09-17 | Mckesson Corporation | Systems and methods for determining and communicating a prescription benefit coverage denial to a prescriber |
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| JP6771385B2 (ja) | 2014-02-28 | 2020-10-21 | メルス ナムローゼ フェンノートシャップ | 二重特異性抗体および医薬組成物 |
| KR20240042540A (ko) | 2014-02-28 | 2024-04-02 | 메뤼스 엔.페. | ErbB-2와 ErbB-3에 결합하는 항체 |
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| CA2991880A1 (fr) | 2015-07-10 | 2017-01-19 | Merus N.V. | Anticorps se liant a un cd3 humain |
| SI3365373T1 (sl) | 2015-10-23 | 2021-08-31 | Merus N.V. | Vezne molekule, ki zaviranjo rast raka |
| US11514137B1 (en) | 2016-03-30 | 2022-11-29 | Mckesson Corporation | Alternative therapy identification system |
| US10999224B1 (en) | 2017-02-01 | 2021-05-04 | Mckesson Corporation | Method and apparatus for parsing an electronic message and constructing multiple differently prioritized messages therefrom |
| MX2019011660A (es) | 2017-03-31 | 2019-11-18 | Merus Nv | Anticuerpos biespecificos que se unen al receptor 2 del factor de crecimiento humano (erbb-2) y receptor 3 del factor de crecimiento humano (erbb3) para usarse en el tratamiento de celulas que tienen un gen de fusion de neuregulina-1 (nrg1). |
| KR20200042485A (ko) | 2017-08-09 | 2020-04-23 | 메뤼스 엔.페. | EGFR 및 cMET에 결합하는 항체 |
| US10862832B1 (en) | 2018-07-24 | 2020-12-08 | Mckesson Corporation | Computing system and method for automatically reversing an action indicated by an electronic message |
| US11043437B2 (en) | 2019-01-07 | 2021-06-22 | Applied Materials, Inc. | Transparent substrate with light blocking edge exclusion zone |
| US11562437B1 (en) | 2019-06-26 | 2023-01-24 | Mckesson Corporation | Method, apparatus, and computer program product for providing estimated prescription costs |
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| EP3772518A1 (fr) | 2019-08-07 | 2021-02-10 | Merus N.V. | Domaines variables humains modifiés |
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| US11610240B1 (en) | 2020-02-17 | 2023-03-21 | Mckesson Corporation | Method, apparatus, and computer program product for partitioning prescription transaction costs in an electronic prescription transaction |
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| US11587657B2 (en) | 2020-09-04 | 2023-02-21 | Mckesson Corporation | Method, apparatus, and computer program product for performing an alternative evaluation procedure in response to an electronic message |
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| ES2344070T3 (es) | 2001-07-04 | 2010-08-17 | Chromagenics B.V. | Secuencias de adn con actividad anti-represora. |
| EP1513936A2 (fr) * | 2002-06-14 | 2005-03-16 | Chromagenics B.V. | Utilisation de sequences de blocage de repression pour ameliorer l'expression d e genes |
| ES2362273T3 (es) * | 2002-06-14 | 2011-06-30 | Chromagenics B.V. | Método para la producción simultánea de múltiples proteínas; vectores y células para su uso en el mismo. |
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| EP1572994B1 (fr) | 2002-12-20 | 2007-02-21 | Chromagenics B.V. | Moyens et methodes pour la production d'une proteine par des ouvre-chromatine capable de rendre le chromatine plus accessible aux facteurs de transcription |
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2002
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