DK1399424T3 - Fremgangsmåde til fremstilling af 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepin-5-carboxamid og 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid - Google Patents

Fremgangsmåde til fremstilling af 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepin-5-carboxamid og 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid

Info

Publication number
DK1399424T3
DK1399424T3 DK02774050T DK02774050T DK1399424T3 DK 1399424 T3 DK1399424 T3 DK 1399424T3 DK 02774050 T DK02774050 T DK 02774050T DK 02774050 T DK02774050 T DK 02774050T DK 1399424 T3 DK1399424 T3 DK 1399424T3
Authority
DK
Denmark
Prior art keywords
dibenz
azepine
carboxamide
dihydro
oxo
Prior art date
Application number
DK02774050T
Other languages
English (en)
Inventor
David Alexander Learmonth
Original Assignee
Bial Portela & Ca Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Portela & Ca Sa filed Critical Bial Portela & Ca Sa
Application granted granted Critical
Publication of DK1399424T3 publication Critical patent/DK1399424T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
DK02774050T 2001-05-25 2002-05-22 Fremgangsmåde til fremstilling af 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepin-5-carboxamid og 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid DK1399424T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112812.3A GB0112812D0 (en) 2001-05-25 2001-05-25 Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
PCT/GB2002/002356 WO2002096881A1 (en) 2001-05-25 2002-05-22 Method for preparation of 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and 10,11-dihydro-10-0x0-5h-dibenz/b,f/azepine-5-carboxamide

Publications (1)

Publication Number Publication Date
DK1399424T3 true DK1399424T3 (da) 2008-09-08

Family

ID=9915332

Family Applications (2)

Application Number Title Priority Date Filing Date
DK02774050T DK1399424T3 (da) 2001-05-25 2002-05-22 Fremgangsmåde til fremstilling af 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepin-5-carboxamid og 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid
DK08075527.5T DK1958938T3 (da) 2001-05-25 2002-05-22 Fremgangsmåde til fremstilling af 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08075527.5T DK1958938T3 (da) 2001-05-25 2002-05-22 Fremgangsmåde til fremstilling af 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid

Country Status (23)

Country Link
US (1) US7241886B2 (da)
EP (2) EP1958938B1 (da)
JP (3) JP4323309B2 (da)
KR (1) KR100931916B1 (da)
CN (2) CN1511141B (da)
AR (1) AR035460A1 (da)
AT (2) ATE506351T1 (da)
AU (2) AU2002307863B8 (da)
BR (1) BR0210019A (da)
CA (2) CA2750876C (da)
CY (3) CY1108345T1 (da)
CZ (1) CZ303130B6 (da)
DE (2) DE60239842D1 (da)
DK (2) DK1399424T3 (da)
ES (2) ES2305299T3 (da)
GB (1) GB0112812D0 (da)
HU (1) HU230019B1 (da)
LU (1) LU91603I2 (da)
MX (1) MXPA03010793A (da)
PL (1) PL215305B1 (da)
RU (2) RU2311411C2 (da)
SI (1) SI1399424T1 (da)
WO (1) WO2002096881A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0303615D0 (en) * 2003-02-17 2003-03-19 Novartis Ag Use of organic compounds
ITMI20042230A1 (it) 2004-11-19 2005-02-19 Farchemia Srl Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it) 2004-11-26 2005-02-26 Farchema S R L Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
GB2422149A (en) * 2005-01-14 2006-07-19 Portela & Ca Sa Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0515690D0 (en) 2005-07-29 2005-09-07 Portela & Ca Sa Asymmetric catalytic reduction
GB0517740D0 (en) * 2005-08-31 2005-10-12 Novartis Ag Organic compounds
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
US8372431B2 (en) * 2007-10-26 2013-02-12 Bial-Portela & C.A., S.A. Pharmaceutical composition comprising licarbazepine acetate
US9855277B2 (en) 2009-07-27 2018-01-02 Bial—Portela & Ca, S.A. Use of 5H-dibenz/b,f/azepine-5-carboxamide derivatives for treating fibromyalgia
WO2013008194A2 (en) 2011-07-13 2013-01-17 Ranbaxy Laboratories Limited Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
US20150232426A1 (en) 2012-09-26 2015-08-20 Ranbaxy Laboratories Limited Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate
US11046999B2 (en) 2015-09-16 2021-06-29 PetaOmics, Inc. Methods and compositions for genomic target enrichment and selective DNA sequencing
CN111943347B (zh) * 2020-07-16 2022-08-30 同济大学 一种铜离子活化过氧乙酸去除废水中卡马西平的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5439390B2 (da) * 1971-09-30 1979-11-27
BE789320A (fr) * 1971-09-30 1973-03-27 Takeda Chemical Industries Ltd Derives de dibenzoxirenazepine
CH633271A5 (en) 1978-04-18 1982-11-30 Ciba Geigy Ag Process for the rearrangement of 10,11-epoxy-10,11-dihydro-5H-dibenz[b,f]azepines to give 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepines
CH642950A5 (en) * 1979-10-30 1984-05-15 Ciba Geigy Ag Process for the preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
IT1272897B (it) * 1995-01-13 1997-07-01 I F C Iniziative Finanziaarie Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PT101732B (pt) * 1995-06-30 1997-12-31 Portela & Ca Sa Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
PT101876B (pt) * 1996-05-27 1999-09-30 Portela & Ca Sa Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
AT408224B (de) 1999-03-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von oxcarbazepin

Also Published As

Publication number Publication date
JP5280252B2 (ja) 2013-09-04
EP1958938A2 (en) 2008-08-20
PL366993A1 (en) 2005-02-07
RU2311411C2 (ru) 2007-11-27
ES2305299T3 (es) 2008-11-01
ES2362688T3 (es) 2011-07-11
CZ303130B6 (cs) 2012-04-18
EP1958938A3 (en) 2008-09-03
KR20040030626A (ko) 2004-04-09
AU2002307863B8 (en) 2007-10-18
CN1511141B (zh) 2011-06-08
WO2002096881A8 (en) 2003-02-27
JP4323309B2 (ja) 2009-09-02
DE60227517D1 (de) 2008-08-21
HUP0400296A2 (hu) 2004-08-30
GB0112812D0 (en) 2001-07-18
RU2007120532A (ru) 2008-12-10
LU91603I2 (fr) 2009-10-28
RU2003137224A (ru) 2005-05-27
DE60239842D1 (de) 2011-06-01
DK1958938T3 (da) 2011-07-25
AU2007221834B2 (en) 2009-02-05
CN1511141A (zh) 2004-07-07
EP1399424A1 (en) 2004-03-24
AU2002307863B2 (en) 2007-09-27
JP2009057376A (ja) 2009-03-19
US20040158060A1 (en) 2004-08-12
EP1399424B8 (en) 2008-10-01
US7241886B2 (en) 2007-07-10
KR100931916B1 (ko) 2009-12-15
ATE506351T1 (de) 2011-05-15
CN101172967A (zh) 2008-05-07
CA2750876A1 (en) 2002-12-05
PL215305B1 (pl) 2013-11-29
JP2009167194A (ja) 2009-07-30
SI1399424T1 (sl) 2008-10-31
WO2002096881A1 (en) 2002-12-05
MXPA03010793A (es) 2004-07-01
CY1108345T1 (el) 2012-01-25
EP1958938B1 (en) 2011-04-20
CA2750876C (en) 2014-10-28
HUP0400296A3 (en) 2008-03-28
EP1399424B1 (en) 2008-07-09
JP2004532263A (ja) 2004-10-21
RU2449992C2 (ru) 2012-05-10
CA2448094C (en) 2011-11-01
CY2009017I2 (el) 2012-01-25
HU230019B1 (hu) 2015-05-28
ATE400560T1 (de) 2008-07-15
AR035460A1 (es) 2004-05-26
AU2007221834A1 (en) 2007-10-25
CZ20033203A3 (cs) 2004-06-16
CA2448094A1 (en) 2002-12-05
CY2009017I1 (el) 2012-01-25
CY1111492T1 (el) 2015-08-05
BR0210019A (pt) 2004-08-10

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