DK1392291T3 - Tripeptidylpeptidaseinhibitorer - Google Patents

Tripeptidylpeptidaseinhibitorer

Info

Publication number
DK1392291T3
DK1392291T3 DK01992570T DK01992570T DK1392291T3 DK 1392291 T3 DK1392291 T3 DK 1392291T3 DK 01992570 T DK01992570 T DK 01992570T DK 01992570 T DK01992570 T DK 01992570T DK 1392291 T3 DK1392291 T3 DK 1392291T3
Authority
DK
Denmark
Prior art keywords
tripeptidyl peptidase
peptidase inhibitors
inhibitors
cholecystokinis
ccks
Prior art date
Application number
DK01992570T
Other languages
English (en)
Inventor
Henry Joseph Janssen P Breslin
Winter Hans Louis Jos De
Michael Joseph Kukla
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1392291T3 publication Critical patent/DK1392291T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
DK01992570T 2000-10-30 2001-10-24 Tripeptidylpeptidaseinhibitorer DK1392291T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24422300P 2000-10-30 2000-10-30
PCT/EP2001/012388 WO2002036116A2 (en) 2000-10-30 2001-10-24 Tripeptidyl peptidase inhibitors

Publications (1)

Publication Number Publication Date
DK1392291T3 true DK1392291T3 (da) 2007-10-08

Family

ID=22921880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01992570T DK1392291T3 (da) 2000-10-30 2001-10-24 Tripeptidylpeptidaseinhibitorer

Country Status (25)

Country Link
US (4) US7125891B2 (da)
EP (1) EP1392291B1 (da)
JP (1) JP2004512365A (da)
KR (1) KR100820598B1 (da)
CN (2) CN101307046B (da)
AT (1) ATE363276T1 (da)
AU (2) AU2479702A (da)
BG (1) BG107729A (da)
CA (1) CA2422617C (da)
CZ (1) CZ20031422A3 (da)
DE (1) DE60128731T2 (da)
DK (1) DK1392291T3 (da)
EA (1) EA006443B1 (da)
EE (1) EE200300168A (da)
ES (1) ES2287185T3 (da)
HU (1) HU230376B1 (da)
IL (2) IL155604A0 (da)
MX (1) MXPA03003868A (da)
NO (1) NO324503B1 (da)
NZ (1) NZ525928A (da)
PL (1) PL205536B1 (da)
PT (1) PT1392291E (da)
SK (1) SK6282003A3 (da)
WO (1) WO2002036116A2 (da)
ZA (1) ZA200303302B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2479702A (en) 2000-10-30 2002-05-15 Janssen Pharmaceutica Nv Tripeptidyl peptidase inhibitors
US7041681B2 (en) * 2002-04-29 2006-05-09 Janssen Pharmaceutica N.V. Compounds as opioid receptor modulators
AU2012268813B2 (en) * 2002-04-29 2015-04-30 Janssen Pharmaceutica N.V. Heterocyclic derivatives as opioid modulators
AU2003280985A1 (en) * 2002-07-10 2004-02-02 Bayer Healthcare Ag Regulation of human tripeptidyl peptidase ii
CA2495179A1 (en) 2002-08-09 2004-02-19 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
WO2004101505A1 (en) * 2003-05-14 2004-11-25 Novo Nordisk A/S Novel compounds for treatment of obesity
DK3112352T3 (da) 2004-03-15 2019-01-28 Janssen Pharmaceutica Nv Opioid-receptor-modulatorer
NZ590570A (en) * 2005-03-14 2012-06-29 Janssen Pharmaceutica Nv Process for the preparation of opioid modulators
KR20080067697A (ko) * 2005-11-11 2008-07-21 에프. 호프만-라 로슈 아게 응고 인자 ｘａ의 억제제로서 카보사이클릭 융합된사이클릭 아민
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
CA2651942A1 (en) 2006-05-11 2008-07-03 Janssen Pharmaceutica N.V. 1,2,3,4-tetrahydro-quinoline derivatives as cetp inhibitors
US7749995B2 (en) 2006-05-11 2010-07-06 Janssen Pharmaceutica Nv 3,4-dihydro-2h-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
GB0709031D0 (en) * 2007-05-10 2007-06-20 Sareum Ltd Pharmaceutical compounds
GB201202027D0 (en) 2012-02-06 2012-03-21 Sareum Ltd Pharmaceutical compounds
DK2634185T3 (da) 2012-03-02 2016-03-21 Sareum Ltd TYK2-kinasehæmmere
EP2708535A1 (en) 2012-05-11 2014-03-19 Les Laboratoires Servier Agents for treating disorders involving modulation of ryanodine receptors
WO2014134306A1 (en) * 2013-03-01 2014-09-04 Zalicus Pharmaceuticals, Ltd. Heterocyclic inhibitors of the sodium channel
US9675587B2 (en) 2013-03-14 2017-06-13 Allergan Holdings Unlimited Company Opioid receptor modulator dosage formulations
GB201617871D0 (en) 2016-10-21 2016-12-07 Sareum Limited Pharmaceutical compounds
EP3539958A4 (en) * 2016-11-01 2020-06-10 Nihon Nohyaku Co., Ltd. N-ALKYLSULFONYLINDOLINE COMPOUND, AGRICULTURAL INSECTICIDE AND HORTICULTURAL COMPRISING THE SAME AND METHOD OF USE
EP4045491A1 (en) * 2019-10-17 2022-08-24 Givaudan SA Substituted azacyles as trmp8 modulators

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE584914A (da) * 1958-11-24
JPS50439B1 (da) * 1970-04-27 1975-01-09
CH543479A (de) * 1970-05-06 1973-10-31 Hoffmann La Roche Verfahren zur Herstellung von Phenyläthylaminderivaten
GB2146026A (en) * 1983-09-07 1985-04-11 Tanabe Seiyaku Co Peptides and process for preparing the same
JPS61227506A (ja) 1985-04-01 1986-10-09 Nippon Tokushu Noyaku Seizo Kk カルバモイルイミダゾ−ル類、その中間体、それらの製法並びに除草剤又は農園芸用殺菌剤
US5159081A (en) 1991-03-29 1992-10-27 Eli Lilly And Company Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
US5338135A (en) 1991-04-11 1994-08-16 Sumitomo Electric Industries, Ltd. Drill and lock screw employed for fastening the same
FR2678938B1 (fr) 1991-07-10 1993-10-08 Rhone Poulenc Rorer Sa Derives de pyrrolidine, leur preparation et les medicaments les contenant.
JPH05339240A (ja) 1992-06-04 1993-12-21 Yamanouchi Pharmaceut Co Ltd テトラヒドロイソキノリンアミド誘導体
SE9402880D0 (sv) 1994-08-30 1994-08-30 Astra Ab New peptide derivatives
FR2733995B1 (fr) 1995-05-09 1997-07-25 Inst Nat Sante Rech Med Inhibiteurs de l'inactivation de neuropeptides endogenes notamment la cholecystokinine, leurs procedes de preparation leur utilisation comme medicaments et procede de criblage de medicaments
FR2735776B1 (fr) * 1995-06-22 1997-07-18 Synthelabo Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
EP0946587A2 (en) * 1996-12-16 1999-10-06 Fujisawa Pharmaceutical Co., Ltd. New amide compounds
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
DK1042288T3 (da) * 1997-12-23 2008-01-28 Inst Nat Sante Rech Med Tripeptidyl-peptidase inhibitorer
US6127381A (en) * 1998-04-28 2000-10-03 Basu; Amaresh Isoquinoline compound melanocortin receptor ligands and methods of using same
BR9815881A (pt) * 1998-06-03 2002-07-23 Gpi Nil Holding Inc Uréias e carbamatos de ácido carboxìlicos n-heterocìclicos e isoésteres de ácido carboxìlico
US6916905B2 (en) * 2000-03-24 2005-07-12 The United States Of America As Represented By The Department Of Health And Human Services Dmt-Tic di-and tri-peptidic derivatives and related compositions and methods of use
AU2479702A (en) 2000-10-30 2002-05-15 Janssen Pharmaceutica Nv Tripeptidyl peptidase inhibitors
FR2816207B1 (fr) 2000-11-08 2003-01-03 Oreal Composition de teinture d'oxydation pour fibres keratiniques comprenant un polyurethane associatif cationique
US6755387B2 (en) 2001-02-08 2004-06-29 Symons Corporation Transition strip for disparate concrete forms

Also Published As

Publication number Publication date
EA200300523A1 (ru) 2003-08-28
NO20031930L (no) 2003-04-29
CZ20031422A3 (cs) 2004-01-14
IL155604A (en) 2009-07-20
ZA200303302B (en) 2004-07-29
HU230376B1 (hu) 2016-03-29
NZ525928A (en) 2005-06-24
AU2479702A (en) 2002-05-15
EE200300168A (et) 2003-06-16
HUP0302770A3 (en) 2009-03-30
ES2287185T3 (es) 2007-12-16
CN1471394A (zh) 2004-01-28
US20060276509A1 (en) 2006-12-07
AU2002224797B2 (en) 2006-10-26
PL361064A1 (en) 2004-09-20
PT1392291E (pt) 2007-08-24
WO2002036116A2 (en) 2002-05-10
ATE363276T1 (de) 2007-06-15
PL205536B1 (pl) 2010-04-30
CN100400040C (zh) 2008-07-09
DE60128731D1 (de) 2007-07-12
WO2002036116A3 (en) 2002-09-26
CA2422617C (en) 2011-07-12
DE60128731T2 (de) 2008-02-07
JP2004512365A (ja) 2004-04-22
EP1392291B1 (en) 2007-05-30
IL155604A0 (en) 2003-11-23
KR100820598B1 (ko) 2008-04-08
EA006443B1 (ru) 2005-12-29
US8247432B2 (en) 2012-08-21
HUP0302770A2 (hu) 2003-12-29
KR20030046465A (ko) 2003-06-12
CN101307046B (zh) 2012-08-15
US20110224255A1 (en) 2011-09-15
US7125891B2 (en) 2006-10-24
CN101307046A (zh) 2008-11-19
US20080108653A1 (en) 2008-05-08
EP1392291A2 (en) 2004-03-03
MXPA03003868A (es) 2003-07-28
CA2422617A1 (en) 2002-05-10
WO2002036116A9 (en) 2003-05-30
NO20031930D0 (no) 2003-04-29
US7947713B2 (en) 2011-05-24
NO324503B1 (no) 2007-11-05
BG107729A (bg) 2004-01-30
US20040034089A1 (en) 2004-02-19
SK6282003A3 (en) 2004-02-03

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