BG107729A - Инхибитори на трипептидилова пептидаза - Google Patents
Инхибитори на трипептидилова пептидаза Download PDFInfo
- Publication number
- BG107729A BG107729A BG107729A BG10772903A BG107729A BG 107729 A BG107729 A BG 107729A BG 107729 A BG107729 A BG 107729A BG 10772903 A BG10772903 A BG 10772903A BG 107729 A BG107729 A BG 107729A
- Authority
- BG
- Bulgaria
- Prior art keywords
- compound
- formula
- mol
- alkyl
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24422300P | 2000-10-30 | 2000-10-30 | |
| PCT/EP2001/012388 WO2002036116A2 (en) | 2000-10-30 | 2001-10-24 | Tripeptidyl peptidase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG107729A true BG107729A (bg) | 2004-01-30 |
Family
ID=22921880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG107729A Pending BG107729A (bg) | 2000-10-30 | 2003-04-16 | Инхибитори на трипептидилова пептидаза |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US7125891B2 (da) |
| EP (1) | EP1392291B1 (da) |
| JP (1) | JP2004512365A (da) |
| KR (1) | KR100820598B1 (da) |
| CN (2) | CN101307046B (da) |
| AT (1) | ATE363276T1 (da) |
| AU (2) | AU2002224797B2 (da) |
| BG (1) | BG107729A (da) |
| CA (1) | CA2422617C (da) |
| CZ (1) | CZ20031422A3 (da) |
| DE (1) | DE60128731T2 (da) |
| DK (1) | DK1392291T3 (da) |
| EA (1) | EA006443B1 (da) |
| EE (1) | EE200300168A (da) |
| ES (1) | ES2287185T3 (da) |
| HU (1) | HU230376B1 (da) |
| IL (2) | IL155604A0 (da) |
| MX (1) | MXPA03003868A (da) |
| NO (1) | NO324503B1 (da) |
| NZ (1) | NZ525928A (da) |
| PL (1) | PL205536B1 (da) |
| PT (1) | PT1392291E (da) |
| SK (1) | SK6282003A3 (da) |
| WO (1) | WO2002036116A2 (da) |
| ZA (1) | ZA200303302B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1392291B1 (en) * | 2000-10-30 | 2007-05-30 | Janssen Pharmaceutica N.V. | Tripeptidyl peptidase inhibitors |
| AU2012268813B2 (en) * | 2002-04-29 | 2015-04-30 | Janssen Pharmaceutica N.V. | Heterocyclic derivatives as opioid modulators |
| US7041681B2 (en) | 2002-04-29 | 2006-05-09 | Janssen Pharmaceutica N.V. | Compounds as opioid receptor modulators |
| WO2004007728A1 (en) * | 2002-07-10 | 2004-01-22 | Bayer Healthcare Ag | Regulation of human tripeptidyl peptidase ii |
| EP1581525A2 (en) | 2002-08-09 | 2005-10-05 | AstraZeneca AB | Compounds having an activity at metabotropic glutamate receptors |
| WO2004101505A1 (en) * | 2003-05-14 | 2004-11-25 | Novo Nordisk A/S | Novel compounds for treatment of obesity |
| ATE516274T1 (de) | 2004-03-15 | 2011-07-15 | Janssen Pharmaceutica Nv | Neue verbindungen als modulatoren des opioidrezeptors |
| EP1863764A1 (en) * | 2005-03-14 | 2007-12-12 | Janssen Pharmaceutica, N.V. | Process for the preparation of opioid modulators |
| EP1948639A2 (en) * | 2005-11-11 | 2008-07-30 | F. Hoffmann-la Roche AG | Novel carbocyclic fused cyclic amines |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| WO2007134149A2 (en) | 2006-05-11 | 2007-11-22 | Janssen Pharmaceutica N.V. | 3,4-dihydro-2h-benzo[1,4]oxazine and thiazine derivatives as cetp inhibitors |
| WO2008079427A1 (en) | 2006-05-11 | 2008-07-03 | Janssen Pharmaceutica N.V. | 1,2,3,4-tetrahydro-quinoline derivatives as cetp inhibitors |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| GB0709031D0 (en) * | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| GB201202027D0 (en) | 2012-02-06 | 2012-03-21 | Sareum Ltd | Pharmaceutical compounds |
| DK2634185T3 (da) | 2012-03-02 | 2016-03-21 | Sareum Ltd | TYK2-kinasehæmmere |
| EP2708535A1 (en) | 2012-05-11 | 2014-03-19 | Les Laboratoires Servier | Agents for treating disorders involving modulation of ryanodine receptors |
| US10208023B2 (en) | 2013-03-01 | 2019-02-19 | Mark G. DeGiacomo | Heterocyclic inhibitors of the sodium channel |
| US9675587B2 (en) | 2013-03-14 | 2017-06-13 | Allergan Holdings Unlimited Company | Opioid receptor modulator dosage formulations |
| GB201617871D0 (en) | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
| BR112019008952A2 (pt) | 2016-11-01 | 2019-07-09 | Nihon Nohyaku Co Ltd | composto de indolina n-alquilsulfonia, inseticida agrícola e hortícola compreendendo o composto e método para usar o inseticida |
| JP2022552401A (ja) * | 2019-10-17 | 2022-12-15 | ジボダン エス エー | Ｔｒｍｐ８モジュレーターとしての置換アザシル |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE584914A (da) * | 1958-11-24 | |||
| JPS50439B1 (da) | 1970-04-27 | 1975-01-09 | ||
| CH543479A (de) * | 1970-05-06 | 1973-10-31 | Hoffmann La Roche | Verfahren zur Herstellung von Phenyläthylaminderivaten |
| GB2146026A (en) * | 1983-09-07 | 1985-04-11 | Tanabe Seiyaku Co | Peptides and process for preparing the same |
| JPS61227506A (ja) | 1985-04-01 | 1986-10-09 | Nippon Tokushu Noyaku Seizo Kk | カルバモイルイミダゾ−ル類、その中間体、それらの製法並びに除草剤又は農園芸用殺菌剤 |
| US5159081A (en) | 1991-03-29 | 1992-10-27 | Eli Lilly And Company | Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists |
| US5338135A (en) | 1991-04-11 | 1994-08-16 | Sumitomo Electric Industries, Ltd. | Drill and lock screw employed for fastening the same |
| FR2678938B1 (fr) * | 1991-07-10 | 1993-10-08 | Rhone Poulenc Rorer Sa | Derives de pyrrolidine, leur preparation et les medicaments les contenant. |
| JPH05339240A (ja) | 1992-06-04 | 1993-12-21 | Yamanouchi Pharmaceut Co Ltd | テトラヒドロイソキノリンアミド誘導体 |
| SE9402880D0 (sv) | 1994-08-30 | 1994-08-30 | Astra Ab | New peptide derivatives |
| FR2733995B1 (fr) | 1995-05-09 | 1997-07-25 | Inst Nat Sante Rech Med | Inhibiteurs de l'inactivation de neuropeptides endogenes notamment la cholecystokinine, leurs procedes de preparation leur utilisation comme medicaments et procede de criblage de medicaments |
| FR2735776B1 (fr) * | 1995-06-22 | 1997-07-18 | Synthelabo | Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique |
| JP2001505585A (ja) * | 1996-12-16 | 2001-04-24 | 藤沢薬品工業株式会社 | 新規アミド化合物およびそれらの一酸化窒素シンターゼ阻害剤としての用途 |
| US5965537A (en) * | 1997-03-10 | 1999-10-12 | Basf Aktiengesellschaft | Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus |
| EP1042288B1 (en) * | 1997-12-23 | 2007-11-07 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Tripeptidyl peptidase inhibitors |
| WO1999055679A1 (en) | 1998-04-28 | 1999-11-04 | Trega Biosciences, Inc. | Isoquinoline compound melanocortin receptor ligands and methods of using same |
| SK18292000A3 (sk) * | 1998-06-03 | 2001-07-10 | Gpi Nil Holdings, Inc. | Močoviny a karbamáty n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie |
| US6916905B2 (en) * | 2000-03-24 | 2005-07-12 | The United States Of America As Represented By The Department Of Health And Human Services | Dmt-Tic di-and tri-peptidic derivatives and related compositions and methods of use |
| EP1392291B1 (en) | 2000-10-30 | 2007-05-30 | Janssen Pharmaceutica N.V. | Tripeptidyl peptidase inhibitors |
| FR2816207B1 (fr) | 2000-11-08 | 2003-01-03 | Oreal | Composition de teinture d'oxydation pour fibres keratiniques comprenant un polyurethane associatif cationique |
| US6755387B2 (en) | 2001-02-08 | 2004-06-29 | Symons Corporation | Transition strip for disparate concrete forms |
-
2001
- 2001-10-24 EP EP01992570A patent/EP1392291B1/en not_active Expired - Lifetime
- 2001-10-24 CN CN2008101078402A patent/CN101307046B/zh not_active Expired - Lifetime
- 2001-10-24 KR KR1020037004180A patent/KR100820598B1/ko active IP Right Grant
- 2001-10-24 SK SK628-2003A patent/SK6282003A3/sk unknown
- 2001-10-24 CN CNB018181015A patent/CN100400040C/zh not_active Expired - Lifetime
- 2001-10-24 ES ES01992570T patent/ES2287185T3/es not_active Expired - Lifetime
- 2001-10-24 CZ CZ20031422A patent/CZ20031422A3/cs unknown
- 2001-10-24 MX MXPA03003868A patent/MXPA03003868A/es active IP Right Grant
- 2001-10-24 PL PL361064A patent/PL205536B1/pl unknown
- 2001-10-24 DE DE60128731T patent/DE60128731T2/de not_active Expired - Lifetime
- 2001-10-24 EA EA200300523A patent/EA006443B1/ru not_active IP Right Cessation
- 2001-10-24 WO PCT/EP2001/012388 patent/WO2002036116A2/en active IP Right Grant
- 2001-10-24 AU AU2002224797A patent/AU2002224797B2/en not_active Expired
- 2001-10-24 US US10/415,623 patent/US7125891B2/en not_active Expired - Lifetime
- 2001-10-24 HU HU0302770A patent/HU230376B1/hu unknown
- 2001-10-24 AT AT01992570T patent/ATE363276T1/de active
- 2001-10-24 JP JP2002538928A patent/JP2004512365A/ja active Pending
- 2001-10-24 NZ NZ525928A patent/NZ525928A/en not_active IP Right Cessation
- 2001-10-24 DK DK01992570T patent/DK1392291T3/da active
- 2001-10-24 AU AU2479702A patent/AU2479702A/xx active Pending
- 2001-10-24 PT PT01992570T patent/PT1392291E/pt unknown
- 2001-10-24 EE EEP200300168A patent/EE200300168A/xx unknown
- 2001-10-24 CA CA2422617A patent/CA2422617C/en not_active Expired - Lifetime
- 2001-10-24 IL IL15560401A patent/IL155604A0/xx unknown
-
2003
- 2003-04-16 BG BG107729A patent/BG107729A/bg active Pending
- 2003-04-28 IL IL155604A patent/IL155604A/en unknown
- 2003-04-29 NO NO20031930A patent/NO324503B1/no not_active IP Right Cessation
- 2003-04-29 ZA ZA200303302A patent/ZA200303302B/en unknown
-
2006
- 2006-08-07 US US11/499,937 patent/US20060276509A1/en not_active Abandoned
-
2007
- 2007-10-30 US US11/928,273 patent/US7947713B2/en not_active Expired - Fee Related
-
2011
- 2011-05-19 US US13/111,010 patent/US8247432B2/en not_active Expired - Lifetime
Also Published As
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