BRPI0413973A - compostos - Google Patents

compostos

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Publication number
BRPI0413973A
BRPI0413973A BRPI0413973-9A BRPI0413973A BRPI0413973A BR PI0413973 A BRPI0413973 A BR PI0413973A BR PI0413973 A BRPI0413973 A BR PI0413973A BR PI0413973 A BRPI0413973 A BR PI0413973A
Authority
BR
Brazil
Prior art keywords
compounds
general formula
relates
enzyme inhibitors
novel compounds
Prior art date
Application number
BRPI0413973-9A
Other languages
English (en)
Inventor
Peter Aranyi
Imre Bata
Sandor Batori
Va Boronkay
Philippe Bovy
Zoltan Kapui
Edit Susan
Tibor Szabo
Katalin Urban-Szabo
Marton Varga
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0413973A publication Critical patent/BRPI0413973A/pt

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    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632—Organic additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
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    • C07D471/04—Ortho-condensed systems

Abstract

"COMPOSTOS". A invenção refere-se a novos compostos da fórmula geral (I), que são inibidores de enzima DPP-IV fortes.
BRPI0413973-9A 2003-08-29 2004-08-27 compostos BRPI0413973A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0302788A HU227684B1 (en) 2003-08-29 2003-08-29 Adamantane and azabicyclo-octane and nonane derivatives and their use as dpp-iv inhibitors
PCT/HU2004/000088 WO2005021536A2 (en) 2003-08-29 2004-08-27 Adamantane and azabicyclo-octane and nonane derivatives, process of their preparation and their use as dpp-iv inhibitors

Publications (1)

Publication Number Publication Date
BRPI0413973A true BRPI0413973A (pt) 2006-10-31

Family

ID=89981602

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413973-9A BRPI0413973A (pt) 2003-08-29 2004-08-27 compostos

Country Status (14)

Country Link
US (2) US7652021B2 (pt)
EP (1) EP1664031B1 (pt)
JP (1) JP4853965B2 (pt)
KR (1) KR20060121838A (pt)
CN (1) CN1845921A (pt)
AT (1) ATE381559T1 (pt)
AU (1) AU2004268832B2 (pt)
BR (1) BRPI0413973A (pt)
CA (1) CA2537123A1 (pt)
DE (1) DE602004010829T2 (pt)
HU (1) HU227684B1 (pt)
IL (1) IL173802A (pt)
MX (1) MXPA06002345A (pt)
WO (1) WO2005021536A2 (pt)

Families Citing this family (30)

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JP2008507541A (ja) * 2004-07-23 2008-03-13 ロイヤルティ，スーザン・マリー ペプチダーゼ阻害剤
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US20060276487A1 (en) 2006-12-07
EP1664031B1 (en) 2007-12-19
US20100160328A1 (en) 2010-06-24
AU2004268832A1 (en) 2005-03-10
ATE381559T1 (de) 2008-01-15
CN1845921A (zh) 2006-10-11
IL173802A0 (en) 2006-07-05
HUP0302788A3 (en) 2008-09-29
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IL173802A (en) 2011-08-31
US7652021B2 (en) 2010-01-26
DE602004010829T2 (de) 2008-12-11
WO2005021536A3 (en) 2005-10-13
HU227684B1 (en) 2011-11-28
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CA2537123A1 (en) 2005-03-10

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