DK1334962T3 - Fremgangsmåder til fremstilling af acylphenylalanin - Google Patents

Fremgangsmåder til fremstilling af acylphenylalanin

Info

Publication number
DK1334962T3
DK1334962T3 DK01974874T DK01974874T DK1334962T3 DK 1334962 T3 DK1334962 T3 DK 1334962T3 DK 01974874 T DK01974874 T DK 01974874T DK 01974874 T DK01974874 T DK 01974874T DK 1334962 T3 DK1334962 T3 DK 1334962T3
Authority
DK
Denmark
Prior art keywords
acylphenylalanine
preparing
methods
solvent
phenylalanine
Prior art date
Application number
DK01974874T
Other languages
Danish (da)
English (en)
Inventor
Michito Sumikawa
Takao Ohgane
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1334962T3 publication Critical patent/DK1334962T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK01974874T 2000-10-18 2001-10-16 Fremgangsmåder til fremstilling af acylphenylalanin DK1334962T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000317603 2000-10-18
PCT/JP2001/009068 WO2002032853A1 (fr) 2000-10-18 2001-10-16 Procede de preparation d'acylphenylalanines

Publications (1)

Publication Number Publication Date
DK1334962T3 true DK1334962T3 (da) 2007-12-10

Family

ID=18796361

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01974874T DK1334962T3 (da) 2000-10-18 2001-10-16 Fremgangsmåder til fremstilling af acylphenylalanin

Country Status (18)

Country Link
US (2) US7030268B2 (zh)
EP (1) EP1334962B1 (zh)
JP (1) JP4158192B2 (zh)
KR (1) KR100783306B1 (zh)
CN (1) CN1273442C (zh)
AT (1) ATE373635T1 (zh)
AU (1) AU2001294264A1 (zh)
BR (1) BR0114728B1 (zh)
CA (1) CA2425533C (zh)
CY (1) CY1107502T1 (zh)
DE (1) DE60130575T2 (zh)
DK (1) DK1334962T3 (zh)
ES (1) ES2290173T3 (zh)
MX (1) MXPA03003483A (zh)
PT (1) PT1334962E (zh)
RU (1) RU2287520C2 (zh)
TW (1) TW575541B (zh)
WO (1) WO2002032853A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001241168B2 (en) * 2000-03-17 2005-06-16 Ajinomoto Co., Inc. Drugs for complications of diabetes and neuropathy and utilization thereof
MXPA03003484A (es) * 2000-10-18 2003-07-14 Ajinomoto Kk Procedimiento para producir cristales de nateglinida.
DE60130575T2 (de) * 2000-10-18 2008-04-30 Ajinomoto Co., Inc. Verfahren zur herstellung von acylphenylalaninen
JPWO2002040010A1 (ja) * 2000-10-24 2004-06-03 味の素株式会社 ナテグリニド含有親水性医薬製剤
EP1334720B1 (en) * 2000-10-24 2008-09-03 Ajinomoto Co., Inc. Nateglinide-containing preparations
CN100422143C (zh) * 2000-10-24 2008-10-01 味之素株式会社 那格列奈b型结晶的制造方法
EP1535900B1 (en) * 2003-11-26 2006-12-27 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. Process for the preparation of nateglinide, preferably in b-form
US7425648B2 (en) 2005-01-03 2008-09-16 A.M.S.A. Anonima Materie Sintetiche E. Affini S.P.A. Process for the preparation of nateglinide, preferably in B-form
KR20070102694A (ko) * 2005-01-31 2007-10-19 아지노모토 가부시키가이샤 혈당 강하제를 함유하는, 내당능 이상, 경계형 당뇨병,인슐린 저항성 및 고인슐린혈증 개선 또는 치료용 의약조성물
KR101399916B1 (ko) * 2006-03-31 2014-05-28 아지노모토 가부시키가이샤 카복실산 클로라이드 화합물의 제조방법
KR20130087485A (ko) 2010-06-14 2013-08-06 씨아이피엘에이 엘티디. 나테글리니드의 제조 방법
CN115340857B (zh) * 2022-08-24 2024-03-26 宁波锋成先进能源材料研究院有限公司 一种原位自乳化纳米驱油剂及其制备方法和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58189121A (ja) 1982-04-30 1983-11-04 Ajinomoto Co Inc インシユリン投与賦活剤
EP0093551B1 (en) * 1982-04-30 1991-01-16 Ajinomoto Co., Inc. Pharmaceutical composition
JPS59190926A (ja) 1983-04-14 1984-10-29 Ajinomoto Co Inc 吸収性付与剤
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
ES2100291T3 (es) * 1991-07-30 1997-06-16 Ajinomoto Kk Cristales de n-(trans-4-isopropilciclohexilcarbonil)-d-fenilalanina y metodos para prepararlos.
JP2969397B2 (ja) * 1991-09-10 1999-11-02 花王株式会社 Ｎ−長鎖アシル−β−アラニンの製造方法
JP3025725B2 (ja) * 1992-11-24 2000-03-27 花王株式会社 Ｎ−長鎖アシルアミノ酸の分離法及び精製法
JPH06256276A (ja) * 1993-03-02 1994-09-13 Kao Corp Ｎ−長鎖アシルアミノ酸塩の製造方法
JPH0717899A (ja) * 1993-07-01 1995-01-20 Ajinomoto Co Inc カルボン酸クロリドの製造法
DE69740161D1 (de) 1996-11-15 2011-05-12 Ajinomoto Kk Nateglinide-Tablettenzubereitungen
US6844006B1 (en) * 1999-07-09 2005-01-18 Pennfield Oil Company Process and apparatus for the preparation of chlortetracycline-containing animal feed compositions
HUP0204109A3 (en) 1999-12-28 2004-06-28 Ajinomoto Kk Oral preparations for diabetes
AU2001241168B2 (en) 2000-03-17 2005-06-16 Ajinomoto Co., Inc. Drugs for complications of diabetes and neuropathy and utilization thereof
MXPA03003484A (es) 2000-10-18 2003-07-14 Ajinomoto Kk Procedimiento para producir cristales de nateglinida.
DE60130575T2 (de) * 2000-10-18 2008-04-30 Ajinomoto Co., Inc. Verfahren zur herstellung von acylphenylalaninen
EP1334720B1 (en) 2000-10-24 2008-09-03 Ajinomoto Co., Inc. Nateglinide-containing preparations
CN100422143C (zh) 2000-10-24 2008-10-01 味之素株式会社 那格列奈b型结晶的制造方法

Also Published As

Publication number Publication date
US20060155143A1 (en) 2006-07-13
WO2002032853A1 (fr) 2002-04-25
KR20030059202A (ko) 2003-07-07
MXPA03003483A (es) 2003-07-14
JPWO2002032853A1 (ja) 2004-02-26
TW575541B (en) 2004-02-11
EP1334962A1 (en) 2003-08-13
CN1481355A (zh) 2004-03-10
ES2290173T3 (es) 2008-02-16
DE60130575T2 (de) 2008-04-30
EP1334962A4 (en) 2005-08-24
BR0114728B1 (pt) 2014-01-14
CY1107502T1 (el) 2013-03-13
EP1334962B1 (en) 2007-09-19
CA2425533A1 (en) 2003-04-10
KR100783306B1 (ko) 2007-12-10
US7659428B2 (en) 2010-02-09
CN1273442C (zh) 2006-09-06
US7030268B2 (en) 2006-04-18
CA2425533C (en) 2010-04-20
RU2287520C2 (ru) 2006-11-20
AU2001294264A1 (en) 2002-04-29
BR0114728A (pt) 2003-10-14
PT1334962E (pt) 2007-10-09
ATE373635T1 (de) 2007-10-15
JP4158192B2 (ja) 2008-10-01
DE60130575D1 (de) 2007-10-31
US20040024219A1 (en) 2004-02-05

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