DK1334174T3 - Paramyxovirusvektor til genoverförsel til det cardiovaskulære system - Google Patents
Paramyxovirusvektor til genoverförsel til det cardiovaskulære systemInfo
- Publication number
- DK1334174T3 DK1334174T3 DK01981031T DK01981031T DK1334174T3 DK 1334174 T3 DK1334174 T3 DK 1334174T3 DK 01981031 T DK01981031 T DK 01981031T DK 01981031 T DK01981031 T DK 01981031T DK 1334174 T3 DK1334174 T3 DK 1334174T3
- Authority
- DK
- Denmark
- Prior art keywords
- cardiovascular system
- vector
- gene transfer
- paramyxovirus vector
- paramyxovirus
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 210000000748 cardiovascular system Anatomy 0.000 title abstract 4
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 208000005069 pulmonary fibrosis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000339942A JP2002142770A (ja) | 2000-11-08 | 2000-11-08 | 循環系への遺伝子送達用パラミクソウイルスベクター |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1334174T3 true DK1334174T3 (da) | 2006-06-26 |
Family
ID=18814933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01981031T DK1334174T3 (da) | 2000-11-08 | 2001-11-08 | Paramyxovirusvektor til genoverförsel til det cardiovaskulære system |
Country Status (13)
Country | Link |
---|---|
US (1) | US20040101965A1 (ja) |
EP (2) | EP1334174B1 (ja) |
JP (1) | JP2002142770A (ja) |
KR (1) | KR100852078B1 (ja) |
CN (1) | CN1555417B (ja) |
AT (1) | ATE323149T1 (ja) |
AU (1) | AU2002212733A1 (ja) |
CA (1) | CA2428073C (ja) |
DE (1) | DE60118771T2 (ja) |
DK (1) | DK1334174T3 (ja) |
ES (1) | ES2260301T3 (ja) |
HK (1) | HK1070100A1 (ja) |
WO (1) | WO2002038726A2 (ja) |
Families Citing this family (28)
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US6490775B1 (en) * | 1999-04-23 | 2002-12-10 | Veri-Tek Inc. | Press operation verification system |
US7226786B2 (en) * | 1999-05-18 | 2007-06-05 | Dnavec Research Inc. | Envelope gene-deficient Paramyxovirus vector |
WO2001018223A1 (fr) | 1999-09-06 | 2001-03-15 | Dnavec Research Inc. | Paramoxyvirus possedant une sequence d'initiation de transcription modifiee |
US7314614B1 (en) | 1999-11-02 | 2008-01-01 | Dnavec Research, Inc. | Recombinant sendai virus vector for introducing exogenous genes to airway epithelia |
EP1270016A4 (en) | 2000-03-30 | 2005-10-19 | Dnavec Research Inc | VACCINE AGAINST AIDS VIRUS CONTAINING A VECTOR OF SENDAI VIRUS |
CN100531802C (zh) | 2000-06-01 | 2009-08-26 | 株式会社载体研究所 | 含有血凝素活性膜蛋白质的假型逆转录病毒载体 |
US20030170897A1 (en) * | 2000-06-27 | 2003-09-11 | Enyu Imai | Virus vector for transferring gene into renal cells |
EP1333088A4 (en) * | 2000-10-06 | 2004-11-24 | Dnavec Research Inc | PARAMYXOVIRUS VECTOR FOR THE INTRODUCTION OF FOREIGN GENES IN SKELETAL MUSCLE |
WO2002042481A1 (fr) | 2000-11-27 | 2002-05-30 | Dnavec Research Inc. | Vecteur paramyxovirus codant pour un gene d'angiogenese et son utilisation |
EP1504766A4 (en) * | 2002-04-30 | 2006-11-02 | Dnavec Research Inc | MEDICAMENT OR GENE SUPPORT COMPOSITION WITH HEMAGGLUTININ ACTIVITY |
EP1548101A4 (en) * | 2002-09-04 | 2006-05-10 | Dnavec Research Inc | METHOD FOR PRODUCING A VIRAL VECTOR CONTAINING A MEMBRANE PROTEIN BINDING WITH THE NEURAMINIDASE FROM GRAM-POSITIVE BACTERIA TO SIALIC ACID AS AN INTEGRAL PART OF THE ENVELOPE |
JPWO2004038029A1 (ja) * | 2002-10-24 | 2006-02-23 | 株式会社ディナベック研究所 | T細胞に遺伝子を導入する方法 |
ATE459707T1 (de) * | 2003-06-30 | 2010-03-15 | Dnavec Research Inc | Negativ-strang rna-virus-vektoren, welche ein gen mit veränderten hypermutierbaren regionen tragen |
KR20060129013A (ko) * | 2004-01-13 | 2006-12-14 | 가부시키가이샤 디나벡크 겐큐쇼 | 면역자극성 사이토카인을 코드하는 마이너스 가닥 rna 바이러스 벡터를 사용하는 종양의 유전자 치료 |
JPWO2005071085A1 (ja) * | 2004-01-22 | 2007-09-06 | 株式会社ディナベック研究所 | ウイルスベクターの製造方法 |
JPWO2005097988A1 (ja) * | 2004-03-23 | 2008-02-28 | 株式会社ディナベック研究所 | 組織の維持および/または修復に関連する骨髄関連細胞 |
KR20080031167A (ko) * | 2005-04-20 | 2008-04-08 | 디나벡크 가부시키가이샤 | 알츠하이머병 치료용의 고도로 안전한 비강투여용 유전자백신 |
CA2612168A1 (en) * | 2005-06-14 | 2006-12-21 | Dnavec Corporation | Methods for producing antibodies |
ES2561060T3 (es) | 2005-10-28 | 2016-02-24 | Id Pharma Co., Ltd. | Transferencia génica en citoblastos epiteliales de las vías respiratorias mediante el uso de vectores de lentivíricos pseudotipados con una proteína espina de virus de ARN |
CN101405389A (zh) * | 2006-01-17 | 2009-04-08 | 生物载体株式会社 | 新型蛋白质表达系统 |
RU2679889C2 (ru) | 2013-04-18 | 2019-02-14 | Армо Байосайенсиз, Инк. | Способы применения интерлейкина-10 для лечения заболеваний и расстройств |
EP3010527B1 (en) | 2013-06-17 | 2018-08-08 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
CN105658232A (zh) | 2013-08-30 | 2016-06-08 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
MX2016005915A (es) | 2013-11-11 | 2016-12-16 | Armo Biosciences Inc | Metodos de uso de interleucina-10 para tratar enfermedades y trastornos. |
CN106573072A (zh) * | 2014-06-02 | 2017-04-19 | 阿尔莫生物科技股份有限公司 | 降低血清胆固醇的方法 |
ES2941234T3 (es) | 2014-10-22 | 2023-05-19 | Armo Biosciences Inc | Métodos de uso de la interleucina-10 para el tratamiento de enfermedades y trastornos |
US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
EP3341012A4 (en) | 2015-08-25 | 2019-03-20 | Armo Biosciences, Inc. | METHOD FOR USE OF INTERLEUKIN-10 FOR THE TREATMENT OF ILLNESSES AND SUFFERING |
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KR20070058607A (ko) | 1999-05-18 | 2007-06-08 | 가부시키가이샤 디나벡크 겐큐쇼 | 엔벨로프 유전자 결손 파라믹소과 바이러스 벡터 |
US20020169306A1 (en) * | 1999-05-18 | 2002-11-14 | Kaio Kitazato | Envelope gene-deficient paramyxovirus vector |
US20030022376A1 (en) * | 1999-05-18 | 2003-01-30 | Kaio Kitazato | Paramyxovirus-derived RNP |
ATE399206T1 (de) | 1999-05-18 | 2008-07-15 | Dnavec Research Inc | Ribonukleoproteinkomplex aus paramyxovirus |
EP1067179A1 (en) | 1999-07-09 | 2001-01-10 | Pierre Fabre Medicament | Method to select attenuated paramyxoviridae useful for vaccines and therapeutics |
WO2001018223A1 (fr) | 1999-09-06 | 2001-03-15 | Dnavec Research Inc. | Paramoxyvirus possedant une sequence d'initiation de transcription modifiee |
US7314614B1 (en) * | 1999-11-02 | 2008-01-01 | Dnavec Research, Inc. | Recombinant sendai virus vector for introducing exogenous genes to airway epithelia |
CN1418252A (zh) * | 2000-01-19 | 2003-05-14 | 株式会社载体研究所 | 副粘病毒属载体在血管内基因转移中的用途 |
EP1270016A4 (en) * | 2000-03-30 | 2005-10-19 | Dnavec Research Inc | VACCINE AGAINST AIDS VIRUS CONTAINING A VECTOR OF SENDAI VIRUS |
CA2322057A1 (en) * | 2000-05-18 | 2001-11-18 | Dnavec Research Inc. | Paramyxovirus vectors used for transfer of foreign genes |
CN100531802C (zh) * | 2000-06-01 | 2009-08-26 | 株式会社载体研究所 | 含有血凝素活性膜蛋白质的假型逆转录病毒载体 |
US20030170897A1 (en) * | 2000-06-27 | 2003-09-11 | Enyu Imai | Virus vector for transferring gene into renal cells |
EP1333088A4 (en) * | 2000-10-06 | 2004-11-24 | Dnavec Research Inc | PARAMYXOVIRUS VECTOR FOR THE INTRODUCTION OF FOREIGN GENES IN SKELETAL MUSCLE |
WO2002042481A1 (fr) * | 2000-11-27 | 2002-05-30 | Dnavec Research Inc. | Vecteur paramyxovirus codant pour un gene d'angiogenese et son utilisation |
JPWO2004038029A1 (ja) * | 2002-10-24 | 2006-02-23 | 株式会社ディナベック研究所 | T細胞に遺伝子を導入する方法 |
JPWO2004067752A1 (ja) * | 2003-01-31 | 2006-05-18 | 株式会社ディナベック研究所 | リボザイムをコードするパラミクソウイルスベクターおよびその利用 |
ATE459707T1 (de) * | 2003-06-30 | 2010-03-15 | Dnavec Research Inc | Negativ-strang rna-virus-vektoren, welche ein gen mit veränderten hypermutierbaren regionen tragen |
AU2004286144A1 (en) * | 2003-11-04 | 2005-05-12 | Dnavec Research Inc. | Method for producing gene transferred dendritic cells |
KR20060129013A (ko) * | 2004-01-13 | 2006-12-14 | 가부시키가이샤 디나벡크 겐큐쇼 | 면역자극성 사이토카인을 코드하는 마이너스 가닥 rna 바이러스 벡터를 사용하는 종양의 유전자 치료 |
JPWO2005097988A1 (ja) * | 2004-03-23 | 2008-02-28 | 株式会社ディナベック研究所 | 組織の維持および/または修復に関連する骨髄関連細胞 |
KR20080031167A (ko) * | 2005-04-20 | 2008-04-08 | 디나벡크 가부시키가이샤 | 알츠하이머병 치료용의 고도로 안전한 비강투여용 유전자백신 |
-
2000
- 2000-11-08 JP JP2000339942A patent/JP2002142770A/ja active Pending
-
2001
- 2001-11-08 WO PCT/JP2001/009786 patent/WO2002038726A2/en active IP Right Grant
- 2001-11-08 AU AU2002212733A patent/AU2002212733A1/en not_active Abandoned
- 2001-11-08 AT AT01981031T patent/ATE323149T1/de not_active IP Right Cessation
- 2001-11-08 DK DK01981031T patent/DK1334174T3/da active
- 2001-11-08 US US10/416,252 patent/US20040101965A1/en not_active Abandoned
- 2001-11-08 KR KR1020037006270A patent/KR100852078B1/ko not_active IP Right Cessation
- 2001-11-08 DE DE60118771T patent/DE60118771T2/de not_active Expired - Lifetime
- 2001-11-08 CA CA2428073A patent/CA2428073C/en not_active Expired - Fee Related
- 2001-11-08 EP EP01981031A patent/EP1334174B1/en not_active Expired - Lifetime
- 2001-11-08 EP EP06002264A patent/EP1662003A3/en not_active Ceased
- 2001-11-08 ES ES01981031T patent/ES2260301T3/es not_active Expired - Lifetime
- 2001-11-08 CN CN018185673A patent/CN1555417B/zh not_active Expired - Fee Related
-
2005
- 2005-04-02 HK HK05102770.7A patent/HK1070100A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1662003A3 (en) | 2006-06-14 |
US20040101965A1 (en) | 2004-05-27 |
CN1555417B (zh) | 2010-04-28 |
AU2002212733A1 (en) | 2002-05-21 |
WO2002038726A2 (en) | 2002-05-16 |
ATE323149T1 (de) | 2006-04-15 |
DE60118771D1 (de) | 2006-05-24 |
ES2260301T3 (es) | 2006-11-01 |
CN1555417A (zh) | 2004-12-15 |
KR20030074617A (ko) | 2003-09-19 |
CA2428073A1 (en) | 2002-05-16 |
EP1662003A2 (en) | 2006-05-31 |
KR100852078B1 (ko) | 2008-08-13 |
EP1334174A2 (en) | 2003-08-13 |
WO2002038726A3 (en) | 2003-03-20 |
CA2428073C (en) | 2012-01-10 |
HK1070100A1 (en) | 2005-06-10 |
DE60118771T2 (de) | 2007-04-12 |
EP1334174B1 (en) | 2006-04-12 |
JP2002142770A (ja) | 2002-05-21 |
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