DK1272161T3 - Lipid-baserede system til afgivelse af lægemidler mod parasitiske infektioner - Google Patents

Lipid-baserede system til afgivelse af lægemidler mod parasitiske infektioner

Info

Publication number
DK1272161T3
DK1272161T3 DK01921262T DK01921262T DK1272161T3 DK 1272161 T3 DK1272161 T3 DK 1272161T3 DK 01921262 T DK01921262 T DK 01921262T DK 01921262 T DK01921262 T DK 01921262T DK 1272161 T3 DK1272161 T3 DK 1272161T3
Authority
DK
Denmark
Prior art keywords
lipid
delivery
based system
parasitic infections
drugs against
Prior art date
Application number
DK01921262T
Other languages
Danish (da)
English (en)
Inventor
Kent Jorgensen
Jesper Davidsen
Charlotte Vermehren
Sven Frokjaer
Ole G Mouritsen
Original Assignee
Liplasome Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liplasome Pharma As filed Critical Liplasome Pharma As
Application granted granted Critical
Publication of DK1272161T3 publication Critical patent/DK1272161T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Cosmetics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DK01921262T 2000-04-12 2001-04-11 Lipid-baserede system til afgivelse af lægemidler mod parasitiske infektioner DK1272161T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000616 2000-04-12
PCT/DK2001/000268 WO2001076556A2 (fr) 2000-04-12 2001-04-11 Systemes d'administration de medicament a base de lipides contenant des derives de lipides degradables de phospholipase a2 a usage medical contre des infections parasitaires

Publications (1)

Publication Number Publication Date
DK1272161T3 true DK1272161T3 (da) 2008-05-19

Family

ID=8159422

Family Applications (3)

Application Number Title Priority Date Filing Date
DK01921262T DK1272161T3 (da) 2000-04-12 2001-04-11 Lipid-baserede system til afgivelse af lægemidler mod parasitiske infektioner
DK01921263T DK1272225T3 (da) 2000-04-12 2001-04-11 Lipidbaserede systemer til målrettet levering af diagnostiske midler
DK01921261T DK1272160T3 (da) 2000-04-12 2001-04-11 Lipidbaseret lægemiddelleveringssystem til topisk applikation

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK01921263T DK1272225T3 (da) 2000-04-12 2001-04-11 Lipidbaserede systemer til målrettet levering af diagnostiske midler
DK01921261T DK1272160T3 (da) 2000-04-12 2001-04-11 Lipidbaseret lægemiddelleveringssystem til topisk applikation

Country Status (11)

Country Link
US (4) US7368254B2 (fr)
EP (3) EP1272225B1 (fr)
JP (3) JP2003530362A (fr)
AT (2) ATE382333T1 (fr)
AU (3) AU2001248302A1 (fr)
CY (2) CY1105792T1 (fr)
DE (3) DE60122304T2 (fr)
DK (3) DK1272161T3 (fr)
ES (3) ES2295149T3 (fr)
PT (3) PT1272225E (fr)
WO (3) WO2001076644A2 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001614A1 (en) * 2000-02-10 2002-01-03 Kent Jorgensen Lipid-based drug delivery systems containing phospholipase A2 degradable lipid derivatives and the therapeutic uses thereof
EP1391207A1 (fr) * 2001-04-24 2004-02-25 Luis Alberto Costa Utilisation d'une phospholipase a2 pour la preparation de compositions pharmaceutiques et/ou cosmetiques pour la prevention et/ou le traitement local et/ou systemique de maladies et/ou de processus provoques par des patogenes intra ou extra cellulaires exprimant des phospholipides de membrane
US20050123925A1 (en) * 2002-11-15 2005-06-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
AU2004264857B2 (en) * 2003-07-09 2010-06-10 Sutter West Bay Hospitals Remote detection of substance delivery to cells
US20050266066A1 (en) * 2003-10-20 2005-12-01 Nof Corporation Phospholipid membrane preparation
WO2005077963A1 (fr) * 2004-01-16 2005-08-25 Institut Superieur Agricole De Beauvais DErivEs de saccharides et d'itols possEdant un groupement O-alkyle ou un groupement O-alkyle et un groupement O-n-butanoyle. Applications comme mEdicaments dans les pathologies prolifEratives tumorales ou bEnignes.
EP1710574A4 (fr) * 2004-01-28 2008-09-17 Ltt Bio Pharma Co Ltd Procede de balayage de compose inoffensif pour la muqueuse gastrique
DE102004010387A1 (de) * 2004-03-03 2005-09-22 Siemens Ag Kontrastmittel für die Röntgen-Computertomographie
WO2006086992A2 (fr) * 2005-02-18 2006-08-24 Liplasome Pharma A/S Systemes d'apport de medicament contenant des derives de promedicament lipidique degradant la phospholipase a2 et utilisations therapeutiques de ces derniers par exemple en tant qu'agents de guerison des blessures ou en tant que ligands de recepteurs actives par un proliferateur au peroxysome
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
WO2006099445A2 (fr) * 2005-03-14 2006-09-21 Massachusetts Institute Of Technology Nanocellules pour le diagnostic et le traitement de maladies et troubles
ES2385513T3 (es) * 2005-10-11 2012-07-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Composición para administración nasal
EP1981488A1 (fr) * 2005-12-23 2008-10-22 Jado Technologies GmbH Moyens et méthodes pour le traitement prophylactique et thérapeutique de maladies allergiques
JP2011026294A (ja) * 2009-06-26 2011-02-10 Canon Inc 化合物
US8993715B2 (en) * 2009-07-06 2015-03-31 Canon Kabushiki Kaisha Labeled protein and method for obtaining the same
NZ598906A (en) 2009-08-21 2014-08-29 Targeted Delivery Technologies Ltd Vesicular formulations
DK177532B1 (en) 2009-09-17 2013-09-08 Bio Bedst Aps Medical use of sPLA2 hydrolysable liposomes
DK177529B1 (en) * 2009-10-23 2013-09-08 Bio Bedst Aps Liposomes with improved storage stability
WO2011102906A1 (fr) * 2010-02-19 2011-08-25 Robert Shorr Système de distribution de nanoémulsions de lipide-huile-eau pouvant recevoir une image
WO2011102905A1 (fr) * 2010-02-19 2011-08-25 Robert Shorr Système d'administration diagnostique de nano-émulsion lipide-huile-eau imageable
WO2011102904A1 (fr) * 2010-02-19 2011-08-25 Robert Shorr Système d'administration thérapeutique de nano-émulsion lipide-huile-eau imageable
WO2013131164A1 (fr) * 2012-03-09 2013-09-12 Universidade Federal De Minas Gerais - Ufmg Composition pharmaceutique contenant des liposomes classiques et liposomes à circulation prolongée pour le traitement de la leishmaniose viscérale
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
WO2014047116A1 (fr) * 2012-09-18 2014-03-27 Comfort Care For Animals Llc Liposomes d'encapsulation
EP3954361A1 (fr) 2015-06-30 2022-02-16 Sequessome Technology Holdings Limited Compositions multiphasiques
EP3538546A1 (fr) 2016-11-14 2019-09-18 Novartis AG Compositions, méthodes et utilisations thérapeutiques associées à une protéine fusogène minion

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0714865B2 (ja) * 1986-10-28 1995-02-22 武田薬品工業株式会社 リポソ−ム製剤およびその製造法
US4837028A (en) * 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5925375A (en) * 1987-05-22 1999-07-20 The Liposome Company, Inc. Therapeutic use of multilamellar liposomal prostaglandin formulations
FR2638639A1 (fr) * 1988-11-08 1990-05-11 Parincos Parfumerie Cosmet Int Composition et procede d'obtention de liposomes oligolamellaires en vue d'une application en cosmetologie et dermatologie topique
US5153000A (en) * 1988-11-22 1992-10-06 Kao Corporation Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome
US4874794A (en) * 1989-04-28 1989-10-17 Lidak Biopharmaceuticals Inflammatory disease treatment
JPH0370491A (ja) 1989-08-04 1991-03-26 Toshiba Corp 電動機制御装置
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
JP3765579B2 (ja) * 1990-08-24 2006-04-12 イーデーエーアー アーゲー 作用物質投与用超微小滴状調剤
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
US5723115A (en) * 1991-05-02 1998-03-03 W. Alton Jones Cell Science Center, Inc. Inhibition of adipose tissue development and obesity
US5484911A (en) * 1993-04-01 1996-01-16 Health Research, Inc. Nucleoside 5'-diphosphate conjugates of ether lipids
DE4408011C1 (de) * 1994-03-10 1995-11-02 Max Delbrueck Centrum Pharmazeutisches Mittel zur Tumortherapie
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
US5942246A (en) * 1996-02-16 1999-08-24 The Liposome Company, Inc. Etherlipid containing multiple lipid liposomes
US5827836A (en) * 1996-11-15 1998-10-27 Clarion Pharmaceuticals Inc. Retinoid glycerol phospholipid conjugates
US6120751A (en) * 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6048736A (en) * 1998-04-29 2000-04-11 Kosak; Kenneth M. Cyclodextrin polymers for carrying and releasing drugs
US6444640B1 (en) * 1999-09-30 2002-09-03 Ludwig Institute For Cancer Research Compositions of trail and DNA damaging drugs and uses thereof

Also Published As

Publication number Publication date
US20030170297A1 (en) 2003-09-11
DE60122304T2 (de) 2007-08-09
ES2295149T3 (es) 2008-04-16
PT1272161E (pt) 2008-02-08
DE60132184D1 (de) 2008-02-14
WO2001076556A3 (fr) 2002-07-11
WO2001076644A2 (fr) 2001-10-18
DE60126072D1 (de) 2007-03-08
EP1272225A2 (fr) 2003-01-08
US20030162748A1 (en) 2003-08-28
AU2001248301A1 (en) 2001-10-23
CY1106462T1 (el) 2012-01-25
US7368254B2 (en) 2008-05-06
WO2001076555A3 (fr) 2002-03-14
PT1272225E (pt) 2007-01-31
AU2001248302A1 (en) 2001-10-23
EP1272161A2 (fr) 2003-01-08
CY1105792T1 (el) 2011-02-02
PT1272160E (pt) 2007-04-30
JP2003530362A (ja) 2003-10-14
DK1272225T3 (da) 2006-12-27
JP2003530339A (ja) 2003-10-14
ATE336267T1 (de) 2006-09-15
DK1272160T3 (da) 2007-05-21
ATE382333T1 (de) 2008-01-15
EP1272160A2 (fr) 2003-01-08
WO2001076644A3 (fr) 2002-03-14
EP1272225B1 (fr) 2006-08-16
DE60126072T2 (de) 2007-11-08
US20030175205A1 (en) 2003-09-18
AU2001248303A1 (en) 2001-10-23
JP2003530338A (ja) 2003-10-14
ES2270991T3 (es) 2007-04-16
ES2280355T3 (es) 2007-09-16
DE60122304D1 (de) 2006-09-28
WO2001076555A2 (fr) 2001-10-18
DE60132184T2 (de) 2009-01-15
WO2001076556A2 (fr) 2001-10-18
US20070134153A1 (en) 2007-06-14
EP1272160B1 (fr) 2007-01-17
EP1272161B1 (fr) 2008-01-02
US7166297B2 (en) 2007-01-23

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