CY1106462T1 - Συστηματα απελευθερωσης φαρμακου με βαση λιπιδιο για τοπικη εφαρμογη - Google Patents

Συστηματα απελευθερωσης φαρμακου με βαση λιπιδιο για τοπικη εφαρμογη

Info

Publication number
CY1106462T1
CY1106462T1 CY20071100522T CY071100522T CY1106462T1 CY 1106462 T1 CY1106462 T1 CY 1106462T1 CY 20071100522 T CY20071100522 T CY 20071100522T CY 071100522 T CY071100522 T CY 071100522T CY 1106462 T1 CY1106462 T1 CY 1106462T1
Authority
CY
Cyprus
Prior art keywords
drug release
topical application
release systems
based drug
lipid based
Prior art date
Application number
CY20071100522T
Other languages
English (en)
Inventor
Kent Jorgensen
Jesper Davidsen
Charlotte Vermehren
Sven Frokjaer
Ole G. Mouritsen
Original Assignee
Liplasome Pharma A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liplasome Pharma A/S filed Critical Liplasome Pharma A/S
Publication of CY1106462T1 publication Critical patent/CY1106462T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Cosmetics (AREA)

Abstract

Η εφεύρεση σχετίζεται με την στόχευση των διαγνωστικών παραγόντων με την χρήση συνθέσεων που βασίζονται στα λιπίδια. Η εφεύρεση είναι χρήσιμη στη διάγνωση διαφόρων ασθενειών που σχετίζονται ή προκύπτουν από αυξημένα επίπεδα της δραστικότητας της έξω-κυτταρικής φωσφολιπάσης (phospholipase) PLA2 στον ασθενή ιστό κ.λ.π. σε καρκινογόνες, μολυσματικές και φλεγμονώδεις συνθήκες.
CY20071100522T 2000-04-12 2007-04-16 Συστηματα απελευθερωσης φαρμακου με βαση λιπιδιο για τοπικη εφαρμογη CY1106462T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000616 2000-04-12
PCT/DK2001/000267 WO2001076555A2 (en) 2000-04-12 2001-04-11 Lipid-based drug delivery systems for topical application

Publications (1)

Publication Number Publication Date
CY1106462T1 true CY1106462T1 (el) 2012-01-25

Family

ID=8159422

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20061101675T CY1105792T1 (el) 2000-04-12 2006-11-16 Συστηματα με βαση λιπιδια για την στοχευση με διαγνωστικους παραγοντες
CY20071100522T CY1106462T1 (el) 2000-04-12 2007-04-16 Συστηματα απελευθερωσης φαρμακου με βαση λιπιδιο για τοπικη εφαρμογη

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20061101675T CY1105792T1 (el) 2000-04-12 2006-11-16 Συστηματα με βαση λιπιδια για την στοχευση με διαγνωστικους παραγοντες

Country Status (11)

Country Link
US (4) US20030170297A1 (el)
EP (3) EP1272225B1 (el)
JP (3) JP2003530338A (el)
AT (2) ATE336267T1 (el)
AU (3) AU2001248303A1 (el)
CY (2) CY1105792T1 (el)
DE (3) DE60122304T2 (el)
DK (3) DK1272225T3 (el)
ES (3) ES2280355T3 (el)
PT (3) PT1272161E (el)
WO (3) WO2001076556A2 (el)

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US20050123925A1 (en) * 2002-11-15 2005-06-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
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US20080113014A1 (en) * 2004-01-28 2008-05-15 Ltt Bio-Pharma Co., Ltd. Method for Screening for Compounds Safe for Gastric Mucosa
DE102004010387A1 (de) * 2004-03-03 2005-09-22 Siemens Ag Kontrastmittel für die Röntgen-Computertomographie
WO2006086992A2 (en) * 2005-02-18 2006-08-24 Liplasome Pharma A/S Drug delivery systems containing phqspholipase a2 degradable lipid prodrug derivatives and the therapeutic uses thereof as. e.g. wound healing agents and peroxisome proliferator activated receptor ligands
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US20090110633A1 (en) * 2005-03-14 2009-04-30 Shiladitya Sengupta Nanocells for Diagnosis and Treatment of Diseases and Disorders
PL1933809T3 (pl) * 2005-10-11 2012-09-28 Yissum Research Development Company Of The Hebrew Univ Of Jerusalem Kompozycje do dostarczania donosowego
WO2007071402A1 (en) * 2005-12-23 2007-06-28 Jado Technologies Gmbh Means and methods for the treatment and prevention of allergic diseases
JP2011026294A (ja) * 2009-06-26 2011-02-10 Canon Inc 化合物
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DE112010003355T5 (de) 2009-08-21 2012-07-12 Targeted Delivery Technologies Ltd. Veskuläre Formulierungen
DK177532B1 (en) 2009-09-17 2013-09-08 Bio Bedst Aps Medical use of sPLA2 hydrolysable liposomes
DK177529B1 (en) * 2009-10-23 2013-09-08 Bio Bedst Aps Liposomes with improved storage stability
WO2011102905A1 (en) * 2010-02-19 2011-08-25 Robert Shorr Imageable lipid-oil-water nanoemulsion diagnostic delivery system
WO2011102906A1 (en) * 2010-02-19 2011-08-25 Robert Shorr Imageable lipid-oil-water nanoemulsion delivery system
WO2011102904A1 (en) * 2010-02-19 2011-08-25 Robert Shorr Imageable lipid-oil-water nanoemulsion therapeutic delivery system
JP2015509507A (ja) * 2012-03-09 2015-03-30 ウニベルシダーヂ フェデラル ヂ ミナス ジェライス−ウエフィエミジェー 内臓リーシュマニア症を治療するための従来型リポソームと長期循環型リポソームを含有する医薬組成物
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Also Published As

Publication number Publication date
US20030162748A1 (en) 2003-08-28
WO2001076555A2 (en) 2001-10-18
US7368254B2 (en) 2008-05-06
WO2001076644A2 (en) 2001-10-18
ES2270991T3 (es) 2007-04-16
PT1272160E (pt) 2007-04-30
US20070134153A1 (en) 2007-06-14
WO2001076556A3 (en) 2002-07-11
EP1272225B1 (en) 2006-08-16
DE60126072D1 (de) 2007-03-08
AU2001248302A1 (en) 2001-10-23
ATE336267T1 (de) 2006-09-15
EP1272160B1 (en) 2007-01-17
JP2003530339A (ja) 2003-10-14
EP1272161A2 (en) 2003-01-08
DK1272160T3 (da) 2007-05-21
WO2001076555A3 (en) 2002-03-14
JP2003530338A (ja) 2003-10-14
EP1272161B1 (en) 2008-01-02
PT1272161E (pt) 2008-02-08
DK1272161T3 (da) 2008-05-19
DE60122304D1 (de) 2006-09-28
JP2003530362A (ja) 2003-10-14
AU2001248301A1 (en) 2001-10-23
ES2280355T3 (es) 2007-09-16
WO2001076556A2 (en) 2001-10-18
US20030170297A1 (en) 2003-09-11
US7166297B2 (en) 2007-01-23
US20030175205A1 (en) 2003-09-18
PT1272225E (pt) 2007-01-31
CY1105792T1 (el) 2011-02-02
ATE382333T1 (de) 2008-01-15
DE60122304T2 (de) 2007-08-09
DE60132184D1 (de) 2008-02-14
AU2001248303A1 (en) 2001-10-23
DK1272225T3 (da) 2006-12-27
DE60132184T2 (de) 2009-01-15
ES2295149T3 (es) 2008-04-16
EP1272160A2 (en) 2003-01-08
DE60126072T2 (de) 2007-11-08
WO2001076644A3 (en) 2002-03-14
EP1272225A2 (en) 2003-01-08

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