ES2180274T3 - Disoluciones nasales. - Google Patents

Disoluciones nasales.

Info

Publication number
ES2180274T3
ES2180274T3 ES99904823T ES99904823T ES2180274T3 ES 2180274 T3 ES2180274 T3 ES 2180274T3 ES 99904823 T ES99904823 T ES 99904823T ES 99904823 T ES99904823 T ES 99904823T ES 2180274 T3 ES2180274 T3 ES 2180274T3
Authority
ES
Spain
Prior art keywords
nasal
dissolutions
liquid
inter alia
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99904823T
Other languages
English (en)
Inventor
Matthias Seidel
Christopher Buckley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Consumer Healthcare SARL
Original Assignee
Novartis Consumer Health SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Consumer Health SA filed Critical Novartis Consumer Health SA
Application granted granted Critical
Publication of ES2180274T3 publication Critical patent/ES2180274T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Una composición farmacéutica líquida nasal que comprende (a) uno o más principios activos adecuados para la administración nasal y seleccionados del grupo que consiste en vasoconstrictores, agentes antialérgicos y corticosteroides; (b) sorbitol; (c) un derivado de la alquil celulosa con 1 a 4 átomos de carbono soluble en agua; (d) un vehículo que está presente en una cantidad de al menos el 90% (m/V) de la composición total, y que se selecciona de agua y mezclas de agua con propilén glicol, agua con glicerol y agua con propilén glicol y glicerol, por lo que en todas estas mezclas está presente el agua en una cantidad de al menos el 95% (m/V); y (e) opcionalmente uno o más excipientes nasalmente aceptables.
ES99904823T 1998-01-30 1999-01-28 Disoluciones nasales. Expired - Lifetime ES2180274T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98810069 1998-01-30

Publications (1)

Publication Number Publication Date
ES2180274T3 true ES2180274T3 (es) 2003-02-01

Family

ID=8235913

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99904823T Expired - Lifetime ES2180274T3 (es) 1998-01-30 1999-01-28 Disoluciones nasales.

Country Status (12)

Country Link
EP (1) EP1051155B1 (es)
JP (1) JP4603687B2 (es)
AT (1) ATE219657T1 (es)
AU (1) AU741364B2 (es)
CA (1) CA2311530C (es)
DE (1) DE69901936T2 (es)
DK (1) DK1051155T3 (es)
ES (1) ES2180274T3 (es)
IL (1) IL136591A (es)
NZ (1) NZ505919A (es)
PT (1) PT1051155E (es)
WO (1) WO1999038492A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030059440A1 (en) * 1998-09-01 2003-03-27 Tim Clarot Composition and method for moisturizing nasal tissue
EP1194145B1 (de) * 1999-06-22 2003-02-05 Boehringer Ingelheim International Gmbh Stabile xylometazolin- und oxymetazolinlösung
DE60209511T2 (de) 2001-09-18 2006-10-05 Nycomed Danmark Aps Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten
BG65734B1 (bg) * 2002-02-22 2009-09-30 Био Терапютикс - Еоод Течен мукоадхезивен фармацевтичен състав
PL373033A1 (en) * 2002-06-20 2005-08-08 Novartis Consumer Health S.A. Nasal compositions comprising a mucopolysaccharide and propylene glycol
WO2004024187A2 (en) * 2002-09-13 2004-03-25 Zicam, Llc. Compositions to reduce congestion and methods for application thereof to the nasal membrane
US20040235807A1 (en) * 2003-05-21 2004-11-25 Weinrich Karl P. Formulations including a topical decongestant and a topical corticosteroid suitable for nasal administration and method for treating obstructive sleep apnea
EP1638523B8 (en) * 2003-06-30 2013-12-25 ALZA Corporation Formulations for coated microprojections containing non-volatile counterions
DE10337186A1 (de) * 2003-08-13 2005-03-17 Merck Patent Gmbh Wässrige Wirkstoff-Lösung
JP4956981B2 (ja) * 2005-01-05 2012-06-20 大正製薬株式会社 オキシメタゾリン含有水性組成物
GB2423711B (en) * 2005-10-24 2007-02-14 Fortune Apex Dev Ltd Method for preparing a pharmaceutical composition with enhanced mucoadhesion
US8940796B2 (en) 2006-02-21 2015-01-27 Wyeth Llc Phenylephrine liquid formulations
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
US20070249727A1 (en) 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
DE102008007198A1 (de) * 2008-02-01 2009-08-13 Infectopharm Arzneimittel Und Consilium Gmbh Oral oder nasal applizierbare Epinephrin- haltige Zubereitungen mit verbesserten Eigenschaften
EP2349206A2 (en) * 2008-10-10 2011-08-03 Schering Corporation Corticosteroid compositions and methods of treatments thereof
DE202013000748U1 (de) 2013-01-24 2013-02-19 Merz Pharma Gmbh & Co. Kgaa Sprühbare flüssige Zubereitung zur insbesondere nasalen Anwendung mit erhöhter lokaler Verweilzeit
EP2759290B1 (de) 2013-01-24 2019-11-06 Merz Pharma GmbH & Co. KGaA Sprühbare flüssige zubereitung zur nasalen anwendung mit erhöhter lokaler verweilzeit
DE102013001151A1 (de) 2013-01-24 2014-07-24 Merz Pharma Gmbh & Co. Kgaa Sprühbare flüssige Zubereitung zur insbesondere nasalen Anwendung mit erhöhter lokaler Verweilzeit
WO2014158118A1 (en) * 2013-03-29 2014-10-02 Santa Farma İlaç Sanayi̇ A.Ş. Suspension composition containing ipratropium and oxymetazoline
EP2978407B1 (en) * 2013-03-29 2020-05-06 Santa Farma Ilaç Sanayi A.S. Aqueous solution composition containing ipratropium and oxymetazoline
WO2015009799A1 (en) * 2013-07-17 2015-01-22 Dow Global Technologies Llc Composition for application to a mucosa comprising a hydroxyalkyl methylcellulose
EP3049060B1 (en) 2013-09-25 2017-10-25 Dow Global Technologies LLC Composition for application to a mucosa comprising a cellulose ether
KR20170094791A (ko) * 2014-12-24 2017-08-21 자드란 - 갈렌스키 라보라토리 디.디. 안정성-개선 부형제로서 해수를 함유하는 비강 조성물
JP2020516688A (ja) * 2017-04-17 2020-06-11 ヒクマ・ファーマシューティカルズ・ユー・エス・エイ・インコーポレイテッド エピネフリンスプレー製剤
WO2019241401A1 (en) * 2018-06-13 2019-12-19 Insys Development Company, Inc. Epinephrine spray formulations
ES2901469T3 (es) 2018-09-11 2022-03-22 Lead Biotherapeutics Ltd Sistema de nanopartículos de dispersión mucoadhesivas y método de producción de las mismas

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62292719A (ja) * 1986-06-12 1987-12-19 Kaken Pharmaceut Co Ltd 外用澄明水溶性製剤
MY102411A (en) * 1986-12-23 1992-06-17 Ciba Geigy Ag Nasal solutions
JPH04327533A (ja) * 1991-04-23 1992-11-17 Lion Corp 抗アレルギー用粘膜局所投与剤
DE69222295T2 (de) * 1992-05-26 1998-04-09 The Procter & Gamble Co., Cincinnati, Ohio Pulverförmige pharmazeutische Zusammensetzung
CA2101126A1 (en) * 1992-08-03 1994-02-04 Yasushi Morita Preparation for local treatment
WO1994022445A2 (en) * 1993-03-26 1994-10-13 Merkus Franciscus W H M Pharmaceutical compositions for intranasal administration of dihydroergotamine, apomorphine and morphine
JPH07109228A (ja) * 1993-10-08 1995-04-25 Earth Chem Corp Ltd リゾチーム配合口腔用組成物
DE69433133T2 (de) * 1993-12-17 2004-04-01 Mochida Pharmaceutical Co. Ltd. Lösliches thrombomodulin enthaltende zubereitung
JP3269770B2 (ja) * 1995-03-02 2002-04-02 参天製薬株式会社 再分散性の優れたイオン性高分子配合水性懸濁点眼剤
DE19549421C2 (de) * 1995-11-10 1999-11-18 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
EP1020194A4 (en) * 1997-10-01 2003-05-21 Wakamoto Pharma Co Ltd OIL / WATER EMULSION COMPILATIONS

Also Published As

Publication number Publication date
DK1051155T3 (da) 2002-09-16
IL136591A (en) 2005-08-31
EP1051155A1 (en) 2000-11-15
PT1051155E (pt) 2002-10-31
NZ505919A (en) 2002-10-25
JP2002501884A (ja) 2002-01-22
AU2519899A (en) 1999-08-16
ATE219657T1 (de) 2002-07-15
WO1999038492A1 (en) 1999-08-05
CA2311530A1 (en) 1999-08-05
EP1051155B1 (en) 2002-06-26
JP4603687B2 (ja) 2010-12-22
AU741364B2 (en) 2001-11-29
IL136591A0 (en) 2001-06-14
DE69901936D1 (de) 2002-08-01
DE69901936T2 (de) 2002-11-28
CA2311530C (en) 2008-06-10

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