DK1226125T3 - Fremgangsmåde til fremstilling af mavesårsmidler - Google Patents

Fremgangsmåde til fremstilling af mavesårsmidler

Info

Publication number
DK1226125T3
DK1226125T3 DK00975934T DK00975934T DK1226125T3 DK 1226125 T3 DK1226125 T3 DK 1226125T3 DK 00975934 T DK00975934 T DK 00975934T DK 00975934 T DK00975934 T DK 00975934T DK 1226125 T3 DK1226125 T3 DK 1226125T3
Authority
DK
Denmark
Prior art keywords
ulcers
preparation
Prior art date
Application number
DK00975934T
Other languages
Danish (da)
English (en)
Inventor
Hartmut Loebermann
Karl-Heinz Caster
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DE2000/003613 external-priority patent/WO2001027349A2/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of DK1226125T3 publication Critical patent/DK1226125T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00975934T 1999-10-28 2000-10-27 Fremgangsmåde til fremstilling af mavesårsmidler DK1226125T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19951960A DE19951960C2 (de) 1999-10-28 1999-10-28 Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
PCT/DE2000/003613 WO2001027349A2 (de) 1999-10-14 2000-10-13 Komponente mit schicht sowie herstellungsverfahren für eine solche schicht

Publications (1)

Publication Number Publication Date
DK1226125T3 true DK1226125T3 (da) 2005-01-24

Family

ID=7927180

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00975934T DK1226125T3 (da) 1999-10-28 2000-10-27 Fremgangsmåde til fremstilling af mavesårsmidler

Country Status (27)

Country Link
US (1) US6686474B2 (no)
EP (1) EP1226125B1 (no)
JP (1) JP2003512458A (no)
KR (1) KR100799472B1 (no)
CN (1) CN1227247C (no)
AR (1) AR029401A1 (no)
AT (1) ATE284873T1 (no)
AU (1) AU780944B2 (no)
BR (1) BR0015220A (no)
CA (1) CA2389163C (no)
CZ (1) CZ20021467A3 (no)
DE (2) DE19951960C2 (no)
DK (1) DK1226125T3 (no)
ES (1) ES2234691T3 (no)
HK (1) HK1048805B (no)
HU (1) HUP0203232A3 (no)
IL (2) IL149358A0 (no)
MX (1) MXPA02004116A (no)
NO (1) NO322802B1 (no)
NZ (1) NZ518699A (no)
PE (1) PE20010762A1 (no)
PL (1) PL212931B1 (no)
PT (1) PT1226125E (no)
SI (1) SI1226125T1 (no)
SK (1) SK287227B6 (no)
WO (1) WO2001030765A2 (no)
ZA (1) ZA200204204B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102775388B (zh) * 2004-09-13 2016-01-20 武田药品工业株式会社 氧化化合物的制备方法和制备装置
KR100771659B1 (ko) * 2005-03-23 2007-10-30 주식회사 카이로제닉스 판토프라졸 및 그 중간체의 제조방법
KR100641534B1 (ko) 2005-07-28 2006-11-01 한미약품 주식회사 에스오메프라졸 및 그의 염의 제조방법

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485869A (en) * 1967-01-31 1969-12-23 Fmc Corp Production of organic peroxy acids
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4619997A (en) * 1984-09-06 1986-10-28 The Upjohn Company Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
JPS62108879A (ja) * 1985-11-05 1987-05-20 Grelan Pharmaceut Co Ltd 置換ベンズイミダゾ−ル類
JPS62201884A (ja) * 1986-02-28 1987-09-05 Tokyo Tanabe Co Ltd ベンズイミダゾール誘導体及びその製造法
JPH0717631B2 (ja) * 1986-03-04 1995-03-01 武田薬品工業株式会社 ピリジニウム誘導体およびその製造法
JPS63183577A (ja) * 1987-01-23 1988-07-28 Grelan Pharmaceut Co Ltd ベンズイミダゾ−ル誘導体
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
JPH01294673A (ja) * 1988-05-23 1989-11-28 Grelan Pharmaceut Co Ltd ベンズイミダゾール誘導体
GB2239453A (en) * 1989-11-27 1991-07-03 Haessle Ab Omeprazole
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
ES2026761A6 (es) * 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
FR2701260B1 (fr) * 1993-02-05 1995-05-05 Esteve Labor Dr Dérivés de 2-[4-(4-azolylbutyl)-1-pipérazinyl]-5-hydroxypyrimidine, leur préparation et leur application en tant que médicaments.
SE521100C2 (sv) * 1995-12-15 2003-09-30 Astra Ab Förfarande för framställning av en bensimidazolförening
SK283805B6 (sk) * 1996-09-09 2004-02-03 Slovakofarma, A. S. Spôsob prípravy omeprazolu
JPH1171371A (ja) * 1997-07-23 1999-03-16 Eisai Co Ltd ピリジン誘導体の製造方法
GB9805558D0 (en) * 1998-03-17 1998-05-13 Knoll Ag Chemical process`
SI20019A (sl) * 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
JP3926936B2 (ja) * 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
AU2596700A (en) * 1999-03-08 2000-09-28 Genentech Inc. Promotion or inhibition of angiogenesis and cardiovascularization

Also Published As

Publication number Publication date
IL149358A0 (en) 2002-11-10
AR029401A1 (es) 2003-06-25
CZ20021467A3 (cs) 2002-07-17
HK1048805A1 (en) 2003-04-17
HUP0203232A2 (hu) 2003-02-28
WO2001030765A2 (de) 2001-05-03
CA2389163C (en) 2009-09-15
NZ518699A (en) 2004-11-26
MXPA02004116A (es) 2002-10-17
DE19951960C2 (de) 2002-06-27
SK5892002A3 (en) 2002-09-10
KR20020057984A (ko) 2002-07-12
DE19951960A1 (de) 2001-05-10
SI1226125T1 (en) 2005-06-30
PT1226125E (pt) 2005-04-29
JP2003512458A (ja) 2003-04-02
ES2234691T3 (es) 2005-07-01
WO2001030765A3 (de) 2001-11-08
NO20021788L (no) 2002-04-16
PL355370A1 (en) 2004-04-19
US6686474B2 (en) 2004-02-03
HUP0203232A3 (en) 2004-01-28
SK287227B6 (sk) 2010-03-08
US20020183363A1 (en) 2002-12-05
NO322802B1 (no) 2006-12-11
CN1227247C (zh) 2005-11-16
NO20021788D0 (no) 2002-04-16
AU1388401A (en) 2001-05-08
CA2389163A1 (en) 2001-05-03
ZA200204204B (en) 2003-08-27
BR0015220A (pt) 2002-06-18
CN1413204A (zh) 2003-04-23
IL149358A (en) 2008-11-26
KR100799472B1 (ko) 2008-01-30
EP1226125B1 (de) 2004-12-15
HK1048805B (zh) 2005-06-30
DE50008978D1 (de) 2005-01-20
AU780944B2 (en) 2005-04-28
PE20010762A1 (es) 2001-09-08
PL212931B1 (pl) 2012-12-31
EP1226125A2 (de) 2002-07-31
ATE284873T1 (de) 2005-01-15

Similar Documents

Publication Publication Date Title
DK1173431T4 (da) Fremgangsmåde til fremstilling af citalopram
DK1105382T3 (da) Fremgangsmåde til fremstilling af citalopram
DK1159274T3 (da) Fremgangsmåde til fremstilling af citalopram
DK1123284T3 (da) Fremgangsmåde til fremstilling af citalopram
DK1165576T3 (da) Fremgangsmåde til fremstilling af amin-platin-komplekser
DK1038008T3 (da) Fremgangsmåde til fremstilling af EGIII-lignende enzymer
DK1032566T3 (da) Fremgangsmåde til fremstilling af citalopram
DK1147083T3 (da) Arylpiperazinyl-cyclohexylindolderivater til behandling af depression
DK1008577T3 (da) Fremgangsmåde til fremstilling af methanol
IS5982A (is) Aðferð til framleiðslu á 5-sýanóþalíði
DK1309581T3 (da) Fremgangsmåde til fremstilling af citalopram
DK1150991T3 (da) Præparater til behandling af inflammatoriske reaktioner
DK1187833T3 (da) Fremgangsmåde til fremstilling af thiamethoxam
DK1028960T3 (da) Fremgangsmåde til fremstilling af thiazolidinedion
DK1296970T3 (da) Fremgangsmåde til fremstilling af citalopram
DK0970939T3 (da) Fremgangsmåde til fremstilling af methanol
DK0985733T3 (da) Fremgangsmåde til fremstilling af cyclodextrin
DK0973769T3 (da) Fremgangsmåde til fremstilling af eprosartan
DK1228056T3 (da) Fremgangsmåde til fremstilling af citalopram
DK0970073T3 (da) Fremgangsmåde til fremstilling af eprosartan
DK1203000T3 (da) Fremgangsmåde til fremstilling af phosphonomethylglycin
DK1240173T3 (da) Fremgangsmåde til fremstilling af N-phosphonomethylglycin
DK1012152T3 (da) Fremgangsmåde til fremstilling af oxazaphosphorin-2-aminer
DK1165483T3 (da) Fremgangsmåde til fremstilling af carbonylfluorid
DK1226125T3 (da) Fremgangsmåde til fremstilling af mavesårsmidler