DK1186607T3 - Optisk aktive pyrrolopyridazinforbindelser - Google Patents
Optisk aktive pyrrolopyridazinforbindelserInfo
- Publication number
- DK1186607T3 DK1186607T3 DK00939072T DK00939072T DK1186607T3 DK 1186607 T3 DK1186607 T3 DK 1186607T3 DK 00939072 T DK00939072 T DK 00939072T DK 00939072 T DK00939072 T DK 00939072T DK 1186607 T3 DK1186607 T3 DK 1186607T3
- Authority
- DK
- Denmark
- Prior art keywords
- optically active
- pharmaceutically acceptable
- alkyl
- active pyrrolopyridazine
- activity
- Prior art date
Links
- YTJAMOLQXDNLJC-UHFFFAOYSA-N N1N=CC=C2N=CC=C21 Chemical class N1N=CC=C2N=CC=C21 YTJAMOLQXDNLJC-UHFFFAOYSA-N 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004211 gastric acid Anatomy 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16767999 | 1999-06-15 | ||
| PCT/JP2000/003895 WO2000077003A1 (en) | 1999-06-15 | 2000-06-15 | Optically active pyrrolopyridazine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1186607T3 true DK1186607T3 (da) | 2003-09-01 |
Family
ID=15854223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00939072T DK1186607T3 (da) | 1999-06-15 | 2000-06-15 | Optisk aktive pyrrolopyridazinforbindelser |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6670360B2 (cs) |
| EP (1) | EP1186607B1 (cs) |
| KR (1) | KR100583663B1 (cs) |
| CN (1) | CN1170829C (cs) |
| AT (1) | ATE240957T1 (cs) |
| AU (1) | AU757611B2 (cs) |
| BR (1) | BR0011666A (cs) |
| CA (1) | CA2375848A1 (cs) |
| CZ (1) | CZ290935B6 (cs) |
| DE (1) | DE60002860T2 (cs) |
| DK (1) | DK1186607T3 (cs) |
| ES (1) | ES2198319T3 (cs) |
| HK (1) | HK1044341B (cs) |
| HU (1) | HUP0201434A3 (cs) |
| IL (2) | IL147088A0 (cs) |
| MX (1) | MXPA01013011A (cs) |
| NO (1) | NO20016099L (cs) |
| NZ (1) | NZ516194A (cs) |
| PL (1) | PL356479A1 (cs) |
| PT (1) | PT1186607E (cs) |
| RU (1) | RU2222541C2 (cs) |
| TR (1) | TR200103685T2 (cs) |
| TW (1) | TWI287014B (cs) |
| WO (1) | WO2000077003A1 (cs) |
| ZA (1) | ZA200110279B (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100750551B1 (ko) * | 2000-02-10 | 2007-08-20 | 상꾜 가부시키가이샤 | 피롤로피리다진 화합물 |
| AU2003266622A1 (en) * | 2002-09-25 | 2004-04-19 | Sankyo Company, Limited | Medicinal composition for inhibiting increase in blood gastrin concentration |
| TW200418479A (en) * | 2002-09-25 | 2004-10-01 | Sankyo Co | Pharmaceutical compositions for the treatment or prevention of visceral pains |
| EP1974730A1 (en) | 2003-11-03 | 2008-10-01 | AstraZeneca AB | Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux |
| KR100958828B1 (ko) * | 2004-09-03 | 2010-05-24 | 주식회사유한양행 | 피롤로[3,2-ｂ]피리딘 유도체 및 그의 제조방법 |
| CN101003537A (zh) * | 2006-01-17 | 2007-07-25 | 上海恒瑞医药有限公司 | 吡咯并哒嗪类衍生物及其制备方法和用途 |
| CN105919998B (zh) | 2009-07-09 | 2021-08-24 | 拉夸里亚创药株式会社 | 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂 |
| CN105367550A (zh) * | 2014-08-11 | 2016-03-02 | 江苏柯菲平医药股份有限公司 | 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL97931A0 (en) | 1990-04-27 | 1992-06-21 | Byk Gulden Lomberg Chem Fab | Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
| WO1992006979A1 (de) | 1990-10-15 | 1992-04-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue diazine |
| JPH07500329A (ja) | 1991-10-25 | 1995-01-12 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | ピロロ−ピリダジン |
| CZ283216B6 (cs) * | 1994-01-19 | 1998-02-18 | Sankyo, Company Limited | Pyrrolopyridazinové deriváty |
-
2000
- 2000-06-13 TW TW089111505A patent/TWI287014B/zh not_active IP Right Cessation
- 2000-06-15 AT AT00939072T patent/ATE240957T1/de not_active IP Right Cessation
- 2000-06-15 CZ CZ20014505A patent/CZ290935B6/cs not_active IP Right Cessation
- 2000-06-15 CA CA002375848A patent/CA2375848A1/en not_active Abandoned
- 2000-06-15 DE DE60002860T patent/DE60002860T2/de not_active Expired - Fee Related
- 2000-06-15 PL PL00356479A patent/PL356479A1/xx not_active Application Discontinuation
- 2000-06-15 DK DK00939072T patent/DK1186607T3/da active
- 2000-06-15 TR TR2001/03685T patent/TR200103685T2/xx unknown
- 2000-06-15 CN CNB008115990A patent/CN1170829C/zh not_active Expired - Fee Related
- 2000-06-15 IL IL14708800A patent/IL147088A0/xx not_active IP Right Cessation
- 2000-06-15 BR BR0011666-1A patent/BR0011666A/pt not_active IP Right Cessation
- 2000-06-15 KR KR1020017016061A patent/KR100583663B1/ko not_active Expired - Fee Related
- 2000-06-15 WO PCT/JP2000/003895 patent/WO2000077003A1/ja not_active Ceased
- 2000-06-15 EP EP00939072A patent/EP1186607B1/en not_active Expired - Lifetime
- 2000-06-15 AU AU54269/00A patent/AU757611B2/en not_active Ceased
- 2000-06-15 MX MXPA01013011A patent/MXPA01013011A/es active IP Right Grant
- 2000-06-15 RU RU2001134010/04A patent/RU2222541C2/ru not_active IP Right Cessation
- 2000-06-15 HU HU0201434A patent/HUP0201434A3/hu unknown
- 2000-06-15 NZ NZ516194A patent/NZ516194A/xx unknown
- 2000-06-15 HK HK02105957.8A patent/HK1044341B/en not_active IP Right Cessation
- 2000-06-15 PT PT00939072T patent/PT1186607E/pt unknown
- 2000-06-15 ES ES00939072T patent/ES2198319T3/es not_active Expired - Lifetime
-
2001
- 2001-12-12 US US10/021,214 patent/US6670360B2/en not_active Expired - Fee Related
- 2001-12-13 ZA ZA200110279A patent/ZA200110279B/xx unknown
- 2001-12-13 IL IL147088A patent/IL147088A/en unknown
- 2001-12-14 NO NO20016099A patent/NO20016099L/no not_active Application Discontinuation
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