DK1140857T3 - Syntese af histamin-dihydrochlorid - Google Patents

Syntese af histamin-dihydrochlorid

Info

Publication number
DK1140857T3
DK1140857T3 DK99968148T DK99968148T DK1140857T3 DK 1140857 T3 DK1140857 T3 DK 1140857T3 DK 99968148 T DK99968148 T DK 99968148T DK 99968148 T DK99968148 T DK 99968148T DK 1140857 T3 DK1140857 T3 DK 1140857T3
Authority
DK
Denmark
Prior art keywords
histamine dihydrochloride
invention disclosed
synthesis
dihydrochloride
smallcaps
Prior art date
Application number
DK99968148T
Other languages
Danish (da)
English (en)
Inventor
Wen-Lung Yeh
Michael Joseph Roth
Casimir Antczak
Mark Wrona
Jeffry David Mcgolrick
Original Assignee
Maxim Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxim Pharm Inc filed Critical Maxim Pharm Inc
Application granted granted Critical
Publication of DK1140857T3 publication Critical patent/DK1140857T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99968148T 1998-12-23 1999-12-20 Syntese af histamin-dihydrochlorid DK1140857T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11393398P 1998-12-23 1998-12-23
US09/467,652 US6403806B1 (en) 1998-12-23 1999-12-20 Synthesis of histamine dihydrochloride
PCT/US1999/030379 WO2000039098A1 (en) 1998-12-23 1999-12-20 Synthesis of histamine dihydrochloride

Publications (1)

Publication Number Publication Date
DK1140857T3 true DK1140857T3 (da) 2008-10-20

Family

ID=26811642

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99968148T DK1140857T3 (da) 1998-12-23 1999-12-20 Syntese af histamin-dihydrochlorid

Country Status (17)

Country Link
US (3) US6403806B1 (es)
EP (1) EP1140857B1 (es)
JP (1) JP4139082B2 (es)
CN (1) CN1155579C (es)
AT (1) ATE399769T1 (es)
AU (1) AU763523B2 (es)
CA (1) CA2356871C (es)
DE (1) DE69939027D1 (es)
DK (1) DK1140857T3 (es)
ES (1) ES2310056T3 (es)
HK (1) HK1040998B (es)
IL (2) IL143570A0 (es)
NZ (1) NZ512935A (es)
PT (1) PT1140857E (es)
TW (1) TWI243166B (es)
WO (1) WO2000039098A1 (es)
ZA (1) ZA200104552B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6590106B2 (en) * 1997-05-09 2003-07-08 Pharm-Eco Laboratories, Inc. Amino acid derivatives and methods of making the same
JP2007533733A (ja) * 2004-04-22 2007-11-22 モル リサーチ アプリケーションズ リミテッド 食物摂取管理の方法
US20080051440A1 (en) * 2004-04-22 2008-02-28 Mor Research Applications Ltd. Compositions for weight management
US7728015B2 (en) * 2004-04-22 2010-06-01 Mor Research Applications Ltd. Compositions for weight management
US20060188528A1 (en) * 2005-02-23 2006-08-24 Ansell Healthcare Products Llc Spreadable warming lubricant
US7709428B2 (en) * 2005-02-23 2010-05-04 Ansell Healthcare Products Llc Thickened spreadable warming lubricant
DE102006060908A1 (de) * 2006-12-20 2008-07-03 Evonik Degussa Gmbh Kontinuierliches Verfahren zur Decarboxylierung von Carbonsäuren
US8770201B2 (en) * 2007-10-26 2014-07-08 Glycobiosciences Inc. Condom with multifunctional coating
CN102477014B (zh) * 2010-11-27 2015-08-19 山东新时代药业有限公司 二盐酸组胺的制备方法
ITMI20110379A1 (it) * 2011-03-10 2012-09-11 Erregierre Spa Procedimento per la preparazione di istamina dicloridrato con elevato grado di purezza
US9452954B2 (en) 2013-03-14 2016-09-27 University Of Georgia Research Foundation, Inc. Method for decarboxylation of amino acids via imine formation
US10487042B2 (en) 2013-03-14 2019-11-26 University Of Georgia Research Foundation, Inc. Method for solvent-free decarboxylation of amino acids via imine formation
US10118898B2 (en) 2013-03-14 2018-11-06 University Of Georgia Research Foundation, Inc. Method for decarboxylation of amino acids via imine formation
CN103288742A (zh) * 2013-06-04 2013-09-11 四川百利药业有限责任公司 一种高纯度英加韦林原料的制备方法
CN103739551B (zh) * 2013-09-24 2016-03-23 国药一心制药有限公司 一种二盐酸组胺的纯化方法
US20160316750A1 (en) * 2013-12-17 2016-11-03 Simon Fraser University Compounds, Compositions and Methods for Attracting and/or Arresting Bed Bugs
CN103739552B (zh) * 2014-01-24 2015-08-26 国药一心制药有限公司 二盐酸组胺的制备方法
CN104402825B (zh) * 2014-12-13 2017-03-15 济南诚汇双达化工有限公司 一种组胺二盐酸盐的合成方法
CN106432089B (zh) * 2016-09-12 2018-09-07 开封制药(集团)有限公司 二盐酸组胺的合成方法
WO2019008594A1 (en) * 2017-07-03 2019-01-10 Jubilant Generics Limited CONTINUOUS PROCESS FOR THE PREPARATION OF 2- (1H-IMIDAZOL-4-YL) ETHANAMINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
US10889549B2 (en) 2017-07-03 2021-01-12 Jubilant Generics Limited Continuous process for the preparation of 2-(1H-imidazol-4-yl) ethanamine and pharmaceutically acceptable salts thereof
CN112266360B (zh) * 2020-10-26 2022-06-10 武汉桀升生物科技有限公司 一种高纯度组胺二盐酸盐的合成方法
CN113045500A (zh) * 2021-03-31 2021-06-29 苏州园方生物科技有限公司 一种组胺二盐酸盐的制备方法
JP7193815B1 (ja) 2021-12-28 2022-12-21 Ｋｍバイオロジクス株式会社 ヒスタミンの製造方法及び医薬品としてのその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE57638C (de) O. ECKARDT in Berlin j N.W., Bandelslr. 14 Verfahren zur Herstellung von Steinkohlenbriquettes auf kaltem Wege
GB430108A (en) * 1934-02-23 1935-06-13 Boot S Pure Drug Company Ltd Improvements relating to the preparation of histamine and its derivatives
GB1008594A (en) 1963-07-03 1965-10-27 Nat Res Dev Process for the production of amines
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
DE3322117A1 (de) * 1983-06-20 1984-12-20 Diamalt AG, 8000 München Verfahren zur herstellung von n(pfeil hoch)(tau)(pfeil hoch)-substituierten histidinderivaten, n(pfeil hoch)(tau)(pfeil hoch)-substituierten histidinderivate und ihre verwendung
NL8800998A (nl) * 1988-04-18 1989-11-16 Cedona Pharm Bv Werkwijze voor het bereiden van een al of niet gesubstitueerd 4(5)-(omega-aminoalkyl) imidazool.
JPH05255204A (ja) 1992-03-11 1993-10-05 Kanegafuchi Chem Ind Co Ltd アミン類の製造法
SE513429C2 (sv) 1992-06-03 2000-09-11 Syntello Inc Preparat för aktivering av naturliga mördarceller, vilket preparat innehåller interferon alfa och biogena aminer

Also Published As

Publication number Publication date
HK1040998A1 (en) 2002-06-28
HK1040998B (zh) 2009-04-24
US6403806B1 (en) 2002-06-11
CN1331681A (zh) 2002-01-16
WO2000039098A1 (en) 2000-07-06
JP2002533445A (ja) 2002-10-08
ATE399769T1 (de) 2008-07-15
WO2000039098A9 (en) 2001-05-17
ES2310056T3 (es) 2008-12-16
IL143570A0 (en) 2002-04-21
IL143570A (en) 2006-08-20
AU2482500A (en) 2000-07-31
PT1140857E (pt) 2008-10-06
AU763523B2 (en) 2003-07-24
CA2356871A1 (en) 2000-07-06
US6528654B2 (en) 2003-03-04
CA2356871C (en) 2010-09-14
US20030138964A1 (en) 2003-07-24
NZ512935A (en) 2003-08-29
US20020035268A1 (en) 2002-03-21
US6620942B2 (en) 2003-09-16
CN1155579C (zh) 2004-06-30
EP1140857A1 (en) 2001-10-10
TWI243166B (en) 2005-11-11
DE69939027D1 (de) 2008-08-14
JP4139082B2 (ja) 2008-08-27
EP1140857B1 (en) 2008-07-02
ZA200104552B (en) 2002-01-16

Similar Documents

Publication Publication Date Title
DK1140857T3 (da) Syntese af histamin-dihydrochlorid
ATE218552T1 (de) 1,2,4-TRIAZIN DERIVAT, DESSEN HERSTELLUNG UND DESSEN VERWENDUNG ALS REFERENZMARKER UM DIE REINHEIT UND STABILITÄT VON ßLAMOTRIGINß ZU BESTIMMEN
PL392726A1 (pl) Nowe związki pośrednie do syntezy związków triazolopirymidyny oraz sposób ich wytwarzania
HUP0100348A2 (hu) Hattagú, egy vagy két nitrogénatomot tartalmazó kondenzál biciklusok, eljárás előállításukra, alkalmazásuk, a vegyületeket tartalmazó gyógyszerkészítmények, valamint intermedierek
DE69713582T2 (de) Zimtsäurederivate und deren verwendung als integrin-antagonisten
IL114599A (en) Substituted pyrimidine compounds their preparation and pharmaceutical compositions containg them
YU69902A (sh) Novi derivati piperazina
ATE249435T1 (de) Neue kristalline form gamma des tert-butylamin salzes von perindopril, verfahren zu deren herstellung und dieses enthaltende arzneimittel
WO1997020823A3 (en) 2-amino quinazoline derivatives as npy receptor antagonists
MX9605915A (es) Derivados de piperazina como antagonistas de 5ht1a.
IL159050A0 (en) Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3, 5-dihydroy heptanoic acid derivatives, and intermediates thereof
HUP0002031A3 (en) Use of benzotiophen derivatives for production pharmaceutical compositions having activity against central nervous system disorders
WO2001010816A3 (de) Substituierte 2-Dialkylaminoalkylbiphenyl-derivate
HUP0203496A3 (en) Novel cyclopropane derivatives, pharmaceutical compositions containing them and method for the production thereof
HUP0101143A3 (en) Pyridin-carboxylic acid derivatives as vitronectin receptor antagonists, process for producing them and pharmaceutical compositions containing them
SE0100824D0 (sv) Method III to obtain microparticles
WO1998018466A3 (en) Anti-neurogenic inflammatory compounds and compositions and methods of use thereof
ITMI20010077A0 (it) Procedimento per la produzione dell'imipenem
IL165568A0 (en) N,N-disubstituted diazocycloalkanes useful for thetreatment of CNS disorders due to serotonergic
CY1108379T1 (el) Συνθεση της διυδροχλωρικης ισταμινης
ATE242253T1 (de) Verbindungen die als antiproliferierende mittel und garft inhibitoren verwendbar sind
ATE360611T1 (de) 2,3,3a,4,9,9a-hexahydro-8-hydroxy-1h- benz(f)indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
MXPA04000953A (es) Derivados sustituidos del acido 5,6,6a,11b-tetrahidro-7-oxa-aza-benzo[c]fluoren-6-carboxilico como antagonista de nmda.
ATE472525T1 (de) C2-substituierte indan-1-one und ihre derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE265999T1 (de) Neuer ltb4-antagonist, verfahren zu dessen herstellung und dessen verwendung als arzneimittel