DK1070083T3 - Krystallinske former af 1-S-[1alfa(2S*,3R*), 9alfa]-6, 10-dioxo-N- (2-ethoxy-5-oxo-tetrahydro-3-furanyl)-9- [[(1 isoquinolyl)carbonyl]octahydro-6H-piridazino[1,2-a][1,2]diazepin-1-carboxamid - Google Patents

Krystallinske former af 1-S-[1alfa(2S*,3R*), 9alfa]-6, 10-dioxo-N- (2-ethoxy-5-oxo-tetrahydro-3-furanyl)-9- [[(1 isoquinolyl)carbonyl]octahydro-6H-piridazino[1,2-a][1,2]diazepin-1-carboxamid

Info

Publication number
DK1070083T3
DK1070083T3 DK99911890T DK99911890T DK1070083T3 DK 1070083 T3 DK1070083 T3 DK 1070083T3 DK 99911890 T DK99911890 T DK 99911890T DK 99911890 T DK99911890 T DK 99911890T DK 1070083 T3 DK1070083 T3 DK 1070083T3
Authority
DK
Denmark
Prior art keywords
piridazino
9alpha
1alpha
diazepine
octahydro
Prior art date
Application number
DK99911890T
Other languages
Danish (da)
English (en)
Inventor
Jean-Yves Godard
Valerie Rognon
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK1070083T3 publication Critical patent/DK1070083T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
DK99911890T 1998-04-08 1999-04-07 Krystallinske former af 1-S-[1alfa(2S*,3R*), 9alfa]-6, 10-dioxo-N- (2-ethoxy-5-oxo-tetrahydro-3-furanyl)-9- [[(1 isoquinolyl)carbonyl]octahydro-6H-piridazino[1,2-a][1,2]diazepin-1-carboxamid DK1070083T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9804367A FR2777279B1 (fr) 1998-04-08 1998-04-08 Nouvelles formes cristallines du 1s-[1alpha(2s*,3r*), 9 alpha] 6,10-dioxo-n-(2-ethoxy-5-oxo-tetrahydro-3-furanyl) -9[[(1-isoquinolyl)carbonyl]amino]octohydro-6h-pyridazino [1,2-a][1,2]diazepine-1-carboxamide

Publications (1)

Publication Number Publication Date
DK1070083T3 true DK1070083T3 (da) 2006-05-15

Family

ID=9524993

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99911890T DK1070083T3 (da) 1998-04-08 1999-04-07 Krystallinske former af 1-S-[1alfa(2S*,3R*), 9alfa]-6, 10-dioxo-N- (2-ethoxy-5-oxo-tetrahydro-3-furanyl)-9- [[(1 isoquinolyl)carbonyl]octahydro-6H-piridazino[1,2-a][1,2]diazepin-1-carboxamid

Country Status (38)

Country Link
US (2) US6544977B1 (et)
EP (1) EP1070083B1 (et)
JP (1) JP2002511485A (et)
KR (1) KR100582981B1 (et)
CN (1) CN1202123C (et)
AP (1) AP1734A (et)
AR (1) AR018328A1 (et)
AT (1) ATE315044T1 (et)
AU (1) AU758042B2 (et)
BG (1) BG64736B1 (et)
BR (1) BR9909549A (et)
CA (1) CA2325629C (et)
CU (1) CU23055A3 (et)
CZ (1) CZ299744B6 (et)
DE (1) DE69929315T2 (et)
DK (1) DK1070083T3 (et)
EA (1) EA002761B1 (et)
EE (1) EE04467B1 (et)
ES (1) ES2253880T3 (et)
FR (1) FR2777279B1 (et)
GE (1) GEP20032974B (et)
HK (1) HK1038575B (et)
HR (1) HRP20000665B1 (et)
HU (1) HU227561B1 (et)
ID (1) ID26290A (et)
IL (2) IL138818A (et)
ME (1) ME01627B (et)
NO (1) NO327995B1 (et)
NZ (1) NZ507199A (et)
PL (1) PL197016B1 (et)
RS (1) RS49916B (et)
SI (1) SI1070083T1 (et)
SK (1) SK286267B6 (et)
TR (1) TR200002914T2 (et)
TW (1) TW522152B (et)
UA (1) UA71563C2 (et)
WO (1) WO1999052935A1 (et)
ZA (1) ZA200005438B (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101479245B (zh) * 2006-06-30 2013-05-22 诺瓦提斯公司 喹啉酮衍生物和其药物组合物
AU2014277867B2 (en) * 2007-12-04 2016-11-03 Arbutus Biopharma Corporation Targeting lipids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5552400A (en) * 1994-06-08 1996-09-03 Sterling Winthrop Inc. Fused-bicyclic lactams as interleukin-1β converting enzyme inhibitors

Also Published As

Publication number Publication date
AR018328A1 (es) 2001-11-14
CZ299744B6 (cs) 2008-11-12
EE04467B1 (et) 2005-04-15
FR2777279B1 (fr) 2004-08-13
CA2325629C (fr) 2013-01-22
CU23055A3 (es) 2005-06-24
ATE315044T1 (de) 2006-02-15
SK14882000A3 (sk) 2001-04-09
SI1070083T1 (sl) 2006-04-30
CN1305491A (zh) 2001-07-25
CA2325629A1 (fr) 1999-10-21
AU3041699A (en) 1999-11-01
NO20005060L (no) 2000-10-06
JP2002511485A (ja) 2002-04-16
ID26290A (id) 2000-12-14
YU60800A (sh) 2002-11-15
HU227561B1 (en) 2011-08-29
IL168047A (en) 2011-10-31
NO327995B1 (no) 2009-11-02
EE200000586A (et) 2002-02-15
EA200001047A1 (ru) 2001-04-23
HUP0101586A3 (en) 2002-11-28
HRP20000665A2 (en) 2001-08-31
AP2000001939A0 (en) 2000-12-31
SK286267B6 (sk) 2008-06-06
FR2777279A1 (fr) 1999-10-15
CZ20003678A3 (cs) 2001-02-14
DE69929315T2 (de) 2006-08-17
NO20005060D0 (no) 2000-10-06
DE69929315D1 (de) 2006-03-30
RS49916B (sr) 2008-09-29
AU758042B2 (en) 2003-03-13
EA002761B1 (ru) 2002-08-29
KR20010034759A (ko) 2001-04-25
GEP20032974B (en) 2003-05-27
AP1734A (en) 2007-03-22
UA71563C2 (uk) 2004-12-15
US20030171365A1 (en) 2003-09-11
US6544977B1 (en) 2003-04-08
BR9909549A (pt) 2000-12-12
BG64736B1 (bg) 2006-01-31
HRP20000665B1 (en) 2008-01-31
HUP0101586A2 (hu) 2001-11-28
WO1999052935A1 (fr) 1999-10-21
PL343350A1 (en) 2001-08-13
HK1038575B (zh) 2006-01-06
ME01627B (me) 2008-09-29
EP1070083A1 (fr) 2001-01-24
BG104829A (en) 2001-05-31
ZA200005438B (en) 2002-01-07
US6946459B2 (en) 2005-09-20
KR100582981B1 (ko) 2006-05-24
ES2253880T3 (es) 2006-06-01
TW522152B (en) 2003-03-01
TR200002914T2 (tr) 2001-02-21
NZ507199A (en) 2002-12-20
PL197016B1 (pl) 2008-02-29
HK1038575A1 (en) 2002-03-22
CN1202123C (zh) 2005-05-18
IL138818A (en) 2008-11-26
EP1070083B1 (fr) 2006-01-04

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