NO20005060L - Krystallinske former av 1S-[1<alfa>(2S*,3R*), 9<alfa>]6,10- diokso-N-(2-etoksy-5-okso-tetrahydro-3-furanyl)-9[[(1- isokinolyl)karbonyl]amino]oktahydro-6H-piridazino[1,2- a][1,2]diazepin-1-karboksamid - Google Patents

Krystallinske former av 1S-[1<alfa>(2S*,3R*), 9<alfa>]6,10- diokso-N-(2-etoksy-5-okso-tetrahydro-3-furanyl)-9[[(1- isokinolyl)karbonyl]amino]oktahydro-6H-piridazino[1,2- a][1,2]diazepin-1-karboksamid

Info

Publication number
NO20005060L
NO20005060L NO20005060A NO20005060A NO20005060L NO 20005060 L NO20005060 L NO 20005060L NO 20005060 A NO20005060 A NO 20005060A NO 20005060 A NO20005060 A NO 20005060A NO 20005060 L NO20005060 L NO 20005060L
Authority
NO
Norway
Prior art keywords
alpha
pyridazino
diazepine
octahydro
isoquinolyl
Prior art date
Application number
NO20005060A
Other languages
English (en)
Other versions
NO20005060D0 (no
NO327995B1 (no
Inventor
Jean-Yves Godard
Valerie Rognon
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO20005060D0 publication Critical patent/NO20005060D0/no
Publication of NO20005060L publication Critical patent/NO20005060L/no
Publication of NO327995B1 publication Critical patent/NO327995B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
NO20005060A 1998-04-08 2000-10-06 Krystallinsk form av vannfritt 1S-[1alfa(2S*,3R*), 9alfa]6,10-diokso-N-(2-etoksy-5-okso-tetrahydro-3-furanyl)-9[[(1-isokinolyl)karbonyl]amino]oktahydro-6H-piridazino[1,2-a][1,2]diazepin-1-karboksamid (form A), fremgangsmate for fremstilling av denne, og anvendelse av den for fremstilling av et medikament NO327995B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9804367A FR2777279B1 (fr) 1998-04-08 1998-04-08 Nouvelles formes cristallines du 1s-[1alpha(2s*,3r*), 9 alpha] 6,10-dioxo-n-(2-ethoxy-5-oxo-tetrahydro-3-furanyl) -9[[(1-isoquinolyl)carbonyl]amino]octohydro-6h-pyridazino [1,2-a][1,2]diazepine-1-carboxamide
PCT/FR1999/000799 WO1999052935A1 (fr) 1998-04-08 1999-04-07 Formes cristallines du 1s-[1alpha (2s*,3r*),9alpha]-6, 10-dioxo-n- (2-ethoxy-5 -oxo-tetrahydro-3 -furanyl) -9-[[(1-isoquinolyl) carbonyl]-amino] octahydro-6h -piridazino[1, 2-a][1,2] diazepine-1- carboxamide

Publications (3)

Publication Number Publication Date
NO20005060D0 NO20005060D0 (no) 2000-10-06
NO20005060L true NO20005060L (no) 2000-10-06
NO327995B1 NO327995B1 (no) 2009-11-02

Family

ID=9524993

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005060A NO327995B1 (no) 1998-04-08 2000-10-06 Krystallinsk form av vannfritt 1S-[1alfa(2S*,3R*), 9alfa]6,10-diokso-N-(2-etoksy-5-okso-tetrahydro-3-furanyl)-9[[(1-isokinolyl)karbonyl]amino]oktahydro-6H-piridazino[1,2-a][1,2]diazepin-1-karboksamid (form A), fremgangsmate for fremstilling av denne, og anvendelse av den for fremstilling av et medikament

Country Status (38)

Country Link
US (2) US6544977B1 (no)
EP (1) EP1070083B1 (no)
JP (1) JP2002511485A (no)
KR (1) KR100582981B1 (no)
CN (1) CN1202123C (no)
AP (1) AP1734A (no)
AR (1) AR018328A1 (no)
AT (1) ATE315044T1 (no)
AU (1) AU758042B2 (no)
BG (1) BG64736B1 (no)
BR (1) BR9909549A (no)
CA (1) CA2325629C (no)
CU (1) CU23055A3 (no)
CZ (1) CZ299744B6 (no)
DE (1) DE69929315T2 (no)
DK (1) DK1070083T3 (no)
EA (1) EA002761B1 (no)
EE (1) EE04467B1 (no)
ES (1) ES2253880T3 (no)
FR (1) FR2777279B1 (no)
GE (1) GEP20032974B (no)
HK (1) HK1038575B (no)
HR (1) HRP20000665B1 (no)
HU (1) HU227561B1 (no)
ID (1) ID26290A (no)
IL (2) IL138818A (no)
ME (1) ME01627B (no)
NO (1) NO327995B1 (no)
NZ (1) NZ507199A (no)
PL (1) PL197016B1 (no)
RS (1) RS49916B (no)
SI (1) SI1070083T1 (no)
SK (1) SK286267B6 (no)
TR (1) TR200002914T2 (no)
TW (1) TW522152B (no)
UA (1) UA71563C2 (no)
WO (1) WO1999052935A1 (no)
ZA (1) ZA200005438B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101402398B1 (ko) * 2006-06-30 2014-06-03 노파르티스 아게 퀴놀리논 유도체 및 이의 제약 조성물
AU2014277867B2 (en) * 2007-12-04 2016-11-03 Arbutus Biopharma Corporation Targeting lipids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5552400A (en) * 1994-06-08 1996-09-03 Sterling Winthrop Inc. Fused-bicyclic lactams as interleukin-1β converting enzyme inhibitors

Also Published As

Publication number Publication date
WO1999052935A1 (fr) 1999-10-21
CU23055A3 (es) 2005-06-24
EE200000586A (et) 2002-02-15
BG64736B1 (bg) 2006-01-31
UA71563C2 (uk) 2004-12-15
EA002761B1 (ru) 2002-08-29
DE69929315D1 (de) 2006-03-30
EA200001047A1 (ru) 2001-04-23
FR2777279A1 (fr) 1999-10-15
CA2325629A1 (fr) 1999-10-21
KR100582981B1 (ko) 2006-05-24
DK1070083T3 (da) 2006-05-15
ME01627B (me) 2008-09-29
HK1038575B (zh) 2006-01-06
GEP20032974B (en) 2003-05-27
FR2777279B1 (fr) 2004-08-13
NO20005060D0 (no) 2000-10-06
CZ299744B6 (cs) 2008-11-12
DE69929315T2 (de) 2006-08-17
NZ507199A (en) 2002-12-20
AP1734A (en) 2007-03-22
HRP20000665A2 (en) 2001-08-31
HUP0101586A2 (hu) 2001-11-28
AU758042B2 (en) 2003-03-13
RS49916B (sr) 2008-09-29
NO327995B1 (no) 2009-11-02
CZ20003678A3 (cs) 2001-02-14
ES2253880T3 (es) 2006-06-01
BR9909549A (pt) 2000-12-12
CN1305491A (zh) 2001-07-25
YU60800A (sh) 2002-11-15
HRP20000665B1 (en) 2008-01-31
EP1070083B1 (fr) 2006-01-04
JP2002511485A (ja) 2002-04-16
SK14882000A3 (sk) 2001-04-09
AU3041699A (en) 1999-11-01
TR200002914T2 (tr) 2001-02-21
HU227561B1 (en) 2011-08-29
IL168047A (en) 2011-10-31
ID26290A (id) 2000-12-14
AP2000001939A0 (en) 2000-12-31
TW522152B (en) 2003-03-01
HUP0101586A3 (en) 2002-11-28
ZA200005438B (en) 2002-01-07
PL197016B1 (pl) 2008-02-29
CN1202123C (zh) 2005-05-18
EP1070083A1 (fr) 2001-01-24
SK286267B6 (sk) 2008-06-06
IL138818A (en) 2008-11-26
PL343350A1 (en) 2001-08-13
HK1038575A1 (en) 2002-03-22
US6946459B2 (en) 2005-09-20
CA2325629C (fr) 2013-01-22
AR018328A1 (es) 2001-11-14
SI1070083T1 (sl) 2006-04-30
KR20010034759A (ko) 2001-04-25
BG104829A (en) 2001-05-31
EE04467B1 (et) 2005-04-15
US20030171365A1 (en) 2003-09-11
US6544977B1 (en) 2003-04-08
ATE315044T1 (de) 2006-02-15

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