DK1053239T3 - Gluccocorticoid-selektive, anti-inflammatoriske midler - Google Patents
Gluccocorticoid-selektive, anti-inflammatoriske midlerInfo
- Publication number
- DK1053239T3 DK1053239T3 DK99906996T DK99906996T DK1053239T3 DK 1053239 T3 DK1053239 T3 DK 1053239T3 DK 99906996 T DK99906996 T DK 99906996T DK 99906996 T DK99906996 T DK 99906996T DK 1053239 T3 DK1053239 T3 DK 1053239T3
- Authority
- DK
- Denmark
- Prior art keywords
- gluccocorticoid
- selective
- inflammatory agents
- mammal
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2394798A | 1998-02-13 | 1998-02-13 | |
| US24783199A | 1999-02-10 | 1999-02-10 | |
| PCT/US1999/003127 WO1999041256A1 (en) | 1998-02-13 | 1999-02-12 | Glucocorticoid-selective anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1053239T3 true DK1053239T3 (da) | 2003-04-22 |
Family
ID=26697833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99906996T DK1053239T3 (da) | 1998-02-13 | 1999-02-12 | Gluccocorticoid-selektive, anti-inflammatoriske midler |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1053239B1 (pl) |
| JP (1) | JP2002503665A (pl) |
| KR (1) | KR20010040935A (pl) |
| CN (1) | CN1119348C (pl) |
| AT (1) | ATE230749T1 (pl) |
| AU (1) | AU766441B2 (pl) |
| BG (1) | BG64317B1 (pl) |
| BR (1) | BR9907788A (pl) |
| CA (1) | CA2320943A1 (pl) |
| DE (1) | DE69904804T2 (pl) |
| DK (1) | DK1053239T3 (pl) |
| ES (1) | ES2192035T3 (pl) |
| HK (1) | HK1033308A1 (pl) |
| HU (1) | HUP0100460A3 (pl) |
| IL (1) | IL137508A0 (pl) |
| NO (1) | NO20004053L (pl) |
| NZ (1) | NZ506013A (pl) |
| PL (1) | PL193323B1 (pl) |
| SK (1) | SK284689B6 (pl) |
| TR (1) | TR200003094T2 (pl) |
| WO (1) | WO1999041256A1 (pl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506766B1 (en) | 1998-02-13 | 2003-01-14 | Abbott Laboratories | Glucocortiocoid-selective antinflammatory agents |
| US6593480B2 (en) * | 1999-09-01 | 2003-07-15 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| CO5180649A1 (es) * | 1999-09-01 | 2002-07-30 | Abbott Lab | Antagonistas de los receptores de los glucocorticoides para el tratamiento de la diabetes para el tratamiento de la diabetes |
| US6436986B1 (en) | 1999-09-01 | 2002-08-20 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| US6329534B1 (en) | 1999-09-01 | 2001-12-11 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| DE60113032T2 (de) | 2000-10-30 | 2006-07-06 | Pfizer Products Inc., Groton | Glukokortikoidrezeptor-Modulatoren |
| WO2003002548A1 (en) * | 2001-06-29 | 2003-01-09 | Abbott Laboratories | A process for the preparation of chiral glucocorticoid receptor agents |
| US6608216B2 (en) | 2001-06-29 | 2003-08-19 | Abbott Laboratories | Process for the preparation of chiral glucocorticoid receptor agents |
| US6518430B1 (en) * | 2001-09-21 | 2003-02-11 | Abbott Laboratories | Process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-F]quinolines and derivatives thereof |
| DE60309829T2 (de) | 2002-01-14 | 2007-09-13 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Glucocorticoidmimetika, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische formulierungen und ihre verwendungen |
| EP1490062B1 (en) | 2002-03-26 | 2007-12-19 | Boehringer Ingelheim Pharmaceuticals Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| AU2003230700A1 (en) | 2002-03-26 | 2003-10-13 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US7282591B2 (en) | 2002-04-11 | 2007-10-16 | Merck & Co., Inc. | 1h-benzo{f}indazol-5-yl derivatives as selective glucocorticoid receptor modulators |
| US7186864B2 (en) | 2002-05-29 | 2007-03-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US7074806B2 (en) | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| EP1532113B1 (en) | 2002-08-21 | 2008-08-06 | Boehringer Ingelheim Pharmaceuticals Inc. | Substituted hihydroquinolines as glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| JP2006504736A (ja) | 2002-10-11 | 2006-02-09 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 選択的プロゲステロンレセプター調節化合物としての５−（１’，１’−シクロアルキル／アルケニル）メチリデン１，２−ジヒドロ−５Ｈ−クロメノ［３，４−ｆ］キノリン |
| JP2006508076A (ja) * | 2002-10-11 | 2006-03-09 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 選択的プロゲステロン受容体モジュレーター化合物としての５−シクロアルケニル５Ｈ−クロメノ［３，４−ｆ］キノリン誘導体 |
| DE20301728U1 (de) | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
| KR20050109922A (ko) | 2003-01-03 | 2005-11-22 | 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 | 1-프로판올과 1-프로필아민 유도체 및 글루코코르티코이드리간드로서의 이들의 용도 |
| US20070088042A1 (en) | 2004-09-09 | 2007-04-19 | Meissner Robert S | Fluorinated 4-azasteroid derivatives as androgen receptor modulators |
| US7235662B2 (en) | 2003-06-11 | 2007-06-26 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
| US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
| EP1675839B1 (en) | 2003-10-16 | 2007-07-11 | Boehringer Ingelheim Pharmaceuticals Inc. | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols |
| US7795272B2 (en) | 2004-03-13 | 2010-09-14 | Boehringer Ingelheim Pharmaceutical, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
| US7635711B2 (en) | 2004-12-27 | 2009-12-22 | Boehringer-Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| PL1944290T3 (pl) * | 2005-09-14 | 2014-07-31 | Ayumi Pharmaceutical Corp | Nowa pochodna 1-2-dihydrochinoliny mająca aktywność wiązania glukokortykoidowego receptora |
| CN102834406A (zh) | 2009-06-16 | 2012-12-19 | 默沙东公司 | 作为糖皮质激素受体激动剂的新的[3.2-c]杂芳基甾体、其组合物和用途 |
| WO2011016050A2 (en) | 2009-07-31 | 2011-02-10 | Cadila Healthcare Limited | Novel compounds as modulators of glucocorticoid receptors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1043326A1 (en) * | 1994-12-22 | 2000-10-11 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
-
1999
- 1999-02-12 CA CA002320943A patent/CA2320943A1/en not_active Abandoned
- 1999-02-12 NZ NZ506013A patent/NZ506013A/xx unknown
- 1999-02-12 AU AU26773/99A patent/AU766441B2/en not_active Ceased
- 1999-02-12 IL IL13750899A patent/IL137508A0/xx unknown
- 1999-02-12 SK SK1197-2000A patent/SK284689B6/sk unknown
- 1999-02-12 DE DE69904804T patent/DE69904804T2/de not_active Expired - Lifetime
- 1999-02-12 EP EP99906996A patent/EP1053239B1/en not_active Expired - Lifetime
- 1999-02-12 CN CN99804902A patent/CN1119348C/zh not_active Expired - Fee Related
- 1999-02-12 HU HU0100460A patent/HUP0100460A3/hu unknown
- 1999-02-12 ES ES99906996T patent/ES2192035T3/es not_active Expired - Lifetime
- 1999-02-12 BR BR9907788-4A patent/BR9907788A/pt not_active Application Discontinuation
- 1999-02-12 JP JP2000531449A patent/JP2002503665A/ja active Pending
- 1999-02-12 DK DK99906996T patent/DK1053239T3/da active
- 1999-02-12 KR KR1020007008850A patent/KR20010040935A/ko not_active Application Discontinuation
- 1999-02-12 TR TR2000/03094T patent/TR200003094T2/xx unknown
- 1999-02-12 PL PL343018A patent/PL193323B1/pl not_active IP Right Cessation
- 1999-02-12 AT AT99906996T patent/ATE230749T1/de active
- 1999-02-12 WO PCT/US1999/003127 patent/WO1999041256A1/en active IP Right Grant
-
2000
- 2000-08-11 NO NO20004053A patent/NO20004053L/no not_active Application Discontinuation
- 2000-08-28 BG BG104719A patent/BG64317B1/bg unknown
-
2001
- 2001-04-19 HK HK01102793A patent/HK1033308A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE230749T1 (de) | 2003-01-15 |
| CN1296486A (zh) | 2001-05-23 |
| CN1119348C (zh) | 2003-08-27 |
| PL343018A1 (en) | 2001-07-30 |
| NO20004053L (no) | 2000-09-11 |
| KR20010040935A (ko) | 2001-05-15 |
| ES2192035T3 (es) | 2003-09-16 |
| PL193323B1 (pl) | 2007-02-28 |
| BG64317B1 (bg) | 2004-09-30 |
| DE69904804T2 (de) | 2003-11-06 |
| AU766441B2 (en) | 2003-10-16 |
| WO1999041256A1 (en) | 1999-08-19 |
| BR9907788A (pt) | 2001-10-30 |
| NZ506013A (en) | 2003-03-28 |
| IL137508A0 (en) | 2001-07-24 |
| TR200003094T2 (tr) | 2001-01-22 |
| CA2320943A1 (en) | 1999-09-19 |
| DE69904804D1 (de) | 2003-02-13 |
| HK1033308A1 (en) | 2001-08-24 |
| HUP0100460A3 (en) | 2003-03-28 |
| NO20004053D0 (no) | 2000-08-11 |
| SK11972000A3 (sk) | 2001-08-06 |
| EP1053239B1 (en) | 2003-01-08 |
| HUP0100460A2 (hu) | 2001-09-28 |
| AU2677399A (en) | 1999-08-30 |
| SK284689B6 (sk) | 2005-09-08 |
| BG104719A (en) | 2001-05-31 |
| JP2002503665A (ja) | 2002-02-05 |
| EP1053239A1 (en) | 2000-11-22 |
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