DK1042324T3 - Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf - Google Patents

Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf

Info

Publication number
DK1042324T3
DK1042324T3 DK98957270T DK98957270T DK1042324T3 DK 1042324 T3 DK1042324 T3 DK 1042324T3 DK 98957270 T DK98957270 T DK 98957270T DK 98957270 T DK98957270 T DK 98957270T DK 1042324 T3 DK1042324 T3 DK 1042324T3
Authority
DK
Denmark
Prior art keywords
inhibition
preparation
methods
pharmaceutical preparations
heterocyclic compounds
Prior art date
Application number
DK98957270T
Other languages
Danish (da)
English (en)
Inventor
Kosrat Amin
Mikael Dahlstroem
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1042324T3 publication Critical patent/DK1042324T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98957270T 1997-11-28 1998-11-18 Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf DK1042324T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds
PCT/SE1998/002091 WO1999028322A1 (en) 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
DK1042324T3 true DK1042324T3 (da) 2003-05-05

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98957270T DK1042324T3 (da) 1997-11-28 1998-11-18 Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf

Country Status (33)

Country Link
US (1) US6518270B1 (de)
EP (1) EP1042324B1 (de)
JP (1) JP2001525322A (de)
KR (1) KR20010032559A (de)
CN (1) CN1142933C (de)
AR (1) AR016972A1 (de)
AT (1) ATE233263T1 (de)
AU (1) AU752187C (de)
BR (1) BR9814755A (de)
CA (1) CA2311798A1 (de)
CZ (1) CZ292349B6 (de)
DE (1) DE69811735T2 (de)
DK (1) DK1042324T3 (de)
EE (1) EE04060B1 (de)
ES (1) ES2191356T3 (de)
HK (1) HK1030216A1 (de)
HU (1) HUP0100601A3 (de)
ID (1) ID24730A (de)
IL (1) IL136145A0 (de)
IS (1) IS5486A (de)
MY (1) MY121032A (de)
NO (1) NO315704B1 (de)
NZ (1) NZ504355A (de)
PL (1) PL340920A1 (de)
PT (1) PT1042324E (de)
RU (1) RU2241000C2 (de)
SE (1) SE9704404D0 (de)
SK (1) SK283904B6 (de)
TR (1) TR200001530T2 (de)
TW (1) TW515798B (de)
UA (1) UA70932C2 (de)
WO (1) WO1999028322A1 (de)
ZA (1) ZA9810468B (de)

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AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
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US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
US7393848B2 (en) 2003-06-30 2008-07-01 Cgi Pharmaceuticals, Inc. Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
US7259164B2 (en) 2003-08-11 2007-08-21 Cgi Pharmaceuticals, Inc. Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
WO2007053131A2 (en) 2004-06-04 2007-05-10 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as antibiotic agents
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CA2575345A1 (en) * 2004-08-02 2006-02-09 Altana Pharma Ag 5-substituted 1h-pyrrolo[3,2-b]pyridines
US8148529B2 (en) 2004-09-03 2012-04-03 Yuhan Corporation Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof
KR100958830B1 (ko) 2004-09-03 2010-05-24 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
ES2342478T3 (es) * 2004-09-03 2010-07-07 Yuhan Corporation Derivados de pirrolo(3,2-c)piridina y procedimiento para la preparacion de los mismos.
BRPI0514695A (pt) 2004-09-03 2008-06-17 Yuhan Corp derivados de pirrol[3, 2-b]piridina e processos para a preparação destes
WO2007024294A2 (en) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
CA2620223A1 (en) 2005-09-02 2007-03-08 Abbott Laboratories Novel imidazo based heterocycles
CA2632476A1 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
CA2654202A1 (en) * 2006-06-06 2007-12-21 Schering Corporation Imidazopyrazines as protein kinase inhibitors
CA2658506C (en) 2006-07-20 2016-01-26 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab 1 inhibitors
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
EP2252617A1 (de) 2008-02-13 2010-11-24 CGI Pharmaceuticals, Inc. 6-arylimidazo[1,2-a]pyrazinderivate, herstellungsverfahren und verfahren zu deren anwendung
KR20170013414A (ko) 2008-12-08 2017-02-06 질레드 코네티컷 인코포레이티드 이미다조피라진 ｓｙｋ 억제제
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
JP5696052B2 (ja) 2008-12-08 2015-04-08 ギリアード コネチカット， インコーポレイテッド イミダゾピラジンｓｙｋ阻害剤
US9562056B2 (en) 2010-03-11 2017-02-07 Gilead Connecticut, Inc. Imidazopyridines Syk inhibitors
WO2013190384A1 (en) 2012-06-19 2013-12-27 Affinium Pharmaceuticals, Inc. Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
PE20160605A1 (es) 2013-07-30 2016-07-20 Gilead Connecticut Inc Formulaciones de inhibidores de la syk
NZ715776A (en) 2013-07-30 2017-04-28 Gilead Connecticut Inc Polymorph of syk inhibitors
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MX2021010131A (es) 2019-02-22 2021-11-18 Kronos Bio Inc Formas sólidas de pirazinas condensadas a manera de inhibidores de syk.

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Also Published As

Publication number Publication date
NO315704B1 (no) 2003-10-13
EE04060B1 (et) 2003-06-16
CN1142933C (zh) 2004-03-24
EP1042324B1 (de) 2003-02-26
NZ504355A (en) 2001-12-21
PL340920A1 (en) 2001-03-12
SK283904B6 (sk) 2004-04-06
MY121032A (en) 2005-12-30
PT1042324E (pt) 2003-06-30
UA70932C2 (uk) 2004-11-15
CN1284078A (zh) 2001-02-14
CA2311798A1 (en) 1999-06-10
ATE233263T1 (de) 2003-03-15
BR9814755A (pt) 2000-10-03
ZA9810468B (en) 1999-05-21
HK1030216A1 (en) 2001-04-27
IL136145A0 (en) 2001-05-20
CZ20001947A3 (cs) 2000-11-15
AU752187C (en) 2003-09-18
RU2241000C2 (ru) 2004-11-27
DE69811735T2 (de) 2003-12-18
WO1999028322A1 (en) 1999-06-10
US6518270B1 (en) 2003-02-11
KR20010032559A (ko) 2001-04-25
NO20002721D0 (no) 2000-05-26
IS5486A (is) 2000-05-10
SE9704404D0 (sv) 1997-11-28
NO20002721L (no) 2000-07-28
CZ292349B6 (cs) 2003-09-17
TW515798B (en) 2003-01-01
HUP0100601A2 (hu) 2001-09-28
HUP0100601A3 (en) 2002-10-28
EE200000315A (et) 2001-10-15
SK6742000A3 (en) 2001-03-12
ID24730A (id) 2000-08-03
AR016972A1 (es) 2001-08-01
TR200001530T2 (tr) 2000-11-21
EP1042324A1 (de) 2000-10-11
DE69811735D1 (de) 2003-04-03
AU752187B2 (en) 2002-09-12
AU1356599A (en) 1999-06-16
ES2191356T3 (es) 2003-09-01
JP2001525322A (ja) 2001-12-11

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