IS6402A - Nýjar greinóttar setnar amínó afleiður af 3-amínó-1-fenýl-1H[1,2,4]tríazóli, aðferðir til framleiðslu á þeim og lyfjasamsetningar sem innihalda þær - Google Patents

Nýjar greinóttar setnar amínó afleiður af 3-amínó-1-fenýl-1H[1,2,4]tríazóli, aðferðir til framleiðslu á þeim og lyfjasamsetningar sem innihalda þær

Info

Publication number
IS6402A
IS6402A IS6402A IS6402A IS6402A IS 6402 A IS6402 A IS 6402A IS 6402 A IS6402 A IS 6402A IS 6402 A IS6402 A IS 6402A IS 6402 A IS6402 A IS 6402A
Authority
IS
Iceland
Prior art keywords
amino
triazole
phenyl
preparation
methods
Prior art date
Application number
IS6402A
Other languages
English (en)
Other versions
IS2315B (is
Inventor
Geslin Michel
Gully Danielle
Jean-Pierre
Roger Pierre
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of IS6402A publication Critical patent/IS6402A/is
Publication of IS2315B publication Critical patent/IS2315B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS6402A 1999-12-17 2002-05-28 Nýjar greinóttar setnar amínó afleiður af 3-amínó-1-fenýl-1H[1,2,4]tríasóli, aðferðir til framleiðslu á þeim og lyfjasamsetningar sem innihalda þær IS2315B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9915935A FR2802530B1 (fr) 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR2000/003536 WO2001044207A2 (fr) 1999-12-17 2000-12-14 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
IS6402A true IS6402A (is) 2002-05-28
IS2315B IS2315B (is) 2007-11-15

Family

ID=9553380

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6402A IS2315B (is) 1999-12-17 2002-05-28 Nýjar greinóttar setnar amínó afleiður af 3-amínó-1-fenýl-1H[1,2,4]tríasóli, aðferðir til framleiðslu á þeim og lyfjasamsetningar sem innihalda þær

Country Status (33)

Country Link
US (1) US6806282B2 (is)
EP (1) EP1242389B1 (is)
JP (1) JP4146641B2 (is)
KR (1) KR100705525B1 (is)
CN (1) CN1293061C (is)
AR (1) AR031837A1 (is)
AT (1) ATE264847T1 (is)
AU (1) AU780711B2 (is)
BR (1) BR0017023A (is)
CA (1) CA2398772C (is)
CO (1) CO5251379A1 (is)
CZ (1) CZ302460B6 (is)
DE (1) DE60010126T2 (is)
DK (1) DK1242389T3 (is)
EA (1) EA004957B1 (is)
EE (1) EE04778B1 (is)
ES (1) ES2219436T3 (is)
FR (1) FR2802530B1 (is)
HU (1) HUP0204080A3 (is)
IL (2) IL150037A0 (is)
IS (1) IS2315B (is)
ME (1) MEP12108A (is)
MX (1) MXPA02006033A (is)
NO (1) NO20022828L (is)
PL (1) PL203819B1 (is)
PT (1) PT1242389E (is)
RS (1) RS50289B (is)
SK (1) SK285994B6 (is)
TR (2) TR200201600T2 (is)
TW (1) TWI289554B (is)
UA (1) UA73333C2 (is)
WO (1) WO2001044207A2 (is)
ZA (1) ZA200204422B (is)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050338A1 (es) * 2003-08-06 2005-05-16 Vertex Pharma Compuestos de aminotriazoles como inhibidores de proteina quinasas
JO3019B1 (ar) 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
JO2784B1 (en) 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
WO2009050186A1 (en) 2007-10-18 2009-04-23 Janssen Pharmaceutica Nv Trisubstituted 1,2,4-triazoles
AR070936A1 (es) * 2008-03-19 2010-05-12 Janssen Pharmaceutica Nv 1,2,4 -triazoles trisustituidos
AU2009245715B2 (en) 2008-05-09 2014-01-09 Janssen Pharmaceutica Nv Trisubstituted pyrazoles as acetylcholine receptor modulators
WO2012054366A2 (en) * 2010-10-21 2012-04-26 Merck Sharp & Dohme Corp. Substituted amino-triazolyl pde10 inhibitors
SI3096756T1 (sl) 2014-01-21 2024-09-30 Neurocrine Biosciences, Inc. CRF1 receptorski antagonisti za zdravljenje kongenitalne adrenalne hiperplazije
CN104059027B (zh) * 2014-07-01 2015-10-28 河北大学 一类含1,2,4-三唑的(e)-甲氧基亚氨基苯乙酸甲酯类化合物及其制备方法和用途
SG11202105930QA (en) 2018-12-07 2021-07-29 Neurocrine Biosciences Inc Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
TWI849432B (zh) * 2019-09-25 2024-07-21 波蘭商摩爾治療股份公司 製造5-(4-((2s,5s)-5-(4-氯芐基)-2-甲基嗎啉基)哌啶-1-基)-1h-1,2,4-三唑-3-胺的方法
CN118252829A (zh) 2019-09-27 2024-06-28 纽罗克里生物科学有限公司 Crf受体拮抗剂及使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3869167D1 (de) * 1987-03-27 1992-04-23 Kumiai Chemical Industry Co Phenyltriazol-derivate und insectizid.
US5795905A (en) * 1995-06-06 1998-08-18 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto
FR2763337B1 (fr) * 1997-05-13 1999-08-20 Sanofi Sa Nouveaux derives du triazole, un procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
DE60010126D1 (de) 2004-05-27
NO20022828D0 (no) 2002-06-13
EA004957B1 (ru) 2004-10-28
ATE264847T1 (de) 2004-05-15
ES2219436T3 (es) 2004-12-01
IL150037A (en) 2007-02-11
CZ20022099A3 (cs) 2002-09-11
PL203819B1 (pl) 2009-11-30
PT1242389E (pt) 2004-08-31
US20030162771A1 (en) 2003-08-28
EP1242389B1 (fr) 2004-04-21
FR2802530A1 (fr) 2001-06-22
WO2001044207B1 (fr) 2002-06-06
IS2315B (is) 2007-11-15
SK285994B6 (sk) 2008-01-07
UA73333C2 (en) 2005-07-15
ZA200204422B (en) 2003-11-26
HK1055947A1 (en) 2004-01-30
FR2802530B1 (fr) 2002-02-22
EP1242389A2 (fr) 2002-09-25
CZ302460B6 (cs) 2011-06-01
CA2398772C (fr) 2011-07-05
DE60010126T2 (de) 2005-04-28
AU780711B2 (en) 2005-04-14
EA200200523A1 (ru) 2002-12-26
HUP0204080A3 (en) 2005-01-28
JP2003516975A (ja) 2003-05-20
BR0017023A (pt) 2002-12-03
WO2001044207A8 (fr) 2001-07-12
WO2001044207A2 (fr) 2001-06-21
CN1293061C (zh) 2007-01-03
AR031837A1 (es) 2003-10-08
NO20022828L (no) 2002-08-19
TR200401775T4 (tr) 2004-09-21
CA2398772A1 (fr) 2001-06-21
IL150037A0 (en) 2002-12-01
HUP0204080A2 (hu) 2003-04-28
CO5251379A1 (es) 2003-02-28
WO2001044207A3 (fr) 2001-12-20
EE200200331A (et) 2003-06-16
SK8502002A3 (en) 2003-02-04
PL355811A1 (en) 2004-05-17
KR100705525B1 (ko) 2007-04-10
RS50289B (sr) 2009-09-08
AU2525901A (en) 2001-06-25
EE04778B1 (et) 2007-02-15
KR20020061002A (ko) 2002-07-19
YU43902A (sh) 2005-03-15
DK1242389T3 (da) 2004-08-09
MXPA02006033A (es) 2003-01-28
US6806282B2 (en) 2004-10-19
CN1434808A (zh) 2003-08-06
JP4146641B2 (ja) 2008-09-10
TWI289554B (en) 2007-11-11
MEP12108A (en) 2010-06-10
TR200201600T2 (tr) 2002-10-21

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