DK1036319T3 - Fremgangsmåde til opnåelse af L-dihydroorotsyre og anvendelse deraf - Google Patents

Fremgangsmåde til opnåelse af L-dihydroorotsyre og anvendelse deraf

Info

Publication number
DK1036319T3
DK1036319T3 DK98963546T DK98963546T DK1036319T3 DK 1036319 T3 DK1036319 T3 DK 1036319T3 DK 98963546 T DK98963546 T DK 98963546T DK 98963546 T DK98963546 T DK 98963546T DK 1036319 T3 DK1036319 T3 DK 1036319T3
Authority
DK
Denmark
Prior art keywords
dihydro
obtaining
carboxylic acid
carboxylic
acid
Prior art date
Application number
DK98963546T
Other languages
Danish (da)
English (en)
Inventor
Ulrike Milbert
Robert Bartlett
Eric Ruuth
Claude Fudali
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK1036319T3 publication Critical patent/DK1036319T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK98963546T 1997-12-11 1998-12-08 Fremgangsmåde til opnåelse af L-dihydroorotsyre og anvendelse deraf DK1036319T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97121848A EP0933633A1 (de) 1997-12-11 1997-12-11 Verfahren zur Erhaltung von L-Dihydroorotinsäure und deren Verwendung

Publications (1)

Publication Number Publication Date
DK1036319T3 true DK1036319T3 (da) 2006-01-16

Family

ID=8227782

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98963546T DK1036319T3 (da) 1997-12-11 1998-12-08 Fremgangsmåde til opnåelse af L-dihydroorotsyre og anvendelse deraf

Country Status (21)

Country Link
US (1) US6545006B1 (de)
EP (2) EP0933633A1 (de)
JP (1) JP4189124B2 (de)
KR (1) KR100700906B1 (de)
CN (1) CN1237345C (de)
AR (1) AR016430A1 (de)
AT (1) ATE305610T1 (de)
AU (1) AU747993B2 (de)
BR (1) BR9813559A (de)
CA (1) CA2315326A1 (de)
CZ (1) CZ299968B6 (de)
DE (1) DE69831752T2 (de)
DK (1) DK1036319T3 (de)
ES (1) ES2248927T3 (de)
HK (1) HK1033171A1 (de)
HU (1) HUP0004510A3 (de)
ID (1) ID24807A (de)
PL (1) PL194068B1 (de)
RU (1) RU2228932C2 (de)
TR (1) TR200001671T2 (de)
WO (1) WO1999030146A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1411373A (zh) * 1999-12-16 2003-04-16 特瓦制药工业有限公司 制备来氟米特的新方法和新晶形的来氟米特
US20150166498A1 (en) * 2012-05-29 2015-06-18 Nai Inc. Dihydroorotic acid dehydrogenase inhibitor
US10708575B2 (en) 2012-06-25 2020-07-07 Sharp Kabushiki Kaisha Display system with diffuse and specular reflective modes
US9679506B2 (en) 2012-06-25 2017-06-13 Sharp Kabushiki Kaisha Multiple function display system
CN102787147B (zh) * 2012-08-31 2014-10-08 南京工业大学 一种酶法制备l-二氢乳清酸的方法
US10699612B2 (en) 2014-10-27 2020-06-30 Sharp Kabushiki Kaisha Display system with specular reflective mode
CN112305097A (zh) * 2020-09-30 2021-02-02 辰欣药业股份有限公司 一种特立氟胺片有关物质的检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2773872A (en) * 1954-04-12 1956-12-11 Merck & Co Inc Dihydroorotic acid
HU178201B (en) * 1977-08-05 1982-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted orto-acids and dihydro-orto-acids and derivatives thereof
DE19539638A1 (de) 1995-10-25 1997-04-30 Hoechst Ag Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen

Also Published As

Publication number Publication date
HUP0004510A1 (hu) 2001-04-28
EP1036319A1 (de) 2000-09-20
PL194068B1 (pl) 2007-04-30
KR100700906B1 (ko) 2007-03-29
CA2315326A1 (en) 1999-06-17
RU2228932C2 (ru) 2004-05-20
DE69831752D1 (de) 2006-02-09
CZ299968B6 (cs) 2009-01-07
ATE305610T1 (de) 2005-10-15
CN1237345C (zh) 2006-01-18
CN1281550A (zh) 2001-01-24
US6545006B1 (en) 2003-04-08
KR20010032978A (ko) 2001-04-25
JP2001526387A (ja) 2001-12-18
TR200001671T2 (tr) 2000-11-21
AR016430A1 (es) 2001-07-04
AU1877599A (en) 1999-06-28
BR9813559A (pt) 2000-10-10
AU747993B2 (en) 2002-05-30
EP1036319B1 (de) 2005-09-28
DE69831752T2 (de) 2006-06-22
HUP0004510A3 (en) 2003-05-28
ES2248927T3 (es) 2006-03-16
HK1033171A1 (en) 2001-08-17
WO1999030146A1 (en) 1999-06-17
CZ20002134A3 (cs) 2000-10-11
EP0933633A1 (de) 1999-08-04
JP4189124B2 (ja) 2008-12-03
ID24807A (id) 2000-08-24
PL341205A1 (en) 2001-03-26

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