DK101385D0 - Molekylaer kloning og ekspression i industrielle mikroorganismearter - Google Patents

Molekylaer kloning og ekspression i industrielle mikroorganismearter

Info

Publication number
DK101385D0
DK101385D0 DK101385A DK101385A DK101385D0 DK 101385 D0 DK101385 D0 DK 101385D0 DK 101385 A DK101385 A DK 101385A DK 101385 A DK101385 A DK 101385A DK 101385 D0 DK101385 D0 DK 101385D0
Authority
DK
Denmark
Prior art keywords
molecycles
cloning
expression
organic species
industrial micro
Prior art date
Application number
DK101385A
Other languages
English (en)
Other versions
DK101385A (da
DK169996B1 (da
Inventor
Johan Pieter Marinus Sanders
Johannes Abel Van Den Berg
Peter Michael Andreoli
Yvonne Johanna Vos
Jan Hendrik Van Ee
Leo J S M Mulleners
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8190976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK101385(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of DK101385D0 publication Critical patent/DK101385D0/da
Publication of DK101385A publication Critical patent/DK101385A/da
Application granted granted Critical
Publication of DK169996B1 publication Critical patent/DK169996B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK101385A 1983-07-06 1985-03-05 Fremgangsmåde til effektiv indføring af DNA i en industriel Bacillus-stammevært, fremgangsmåde til fremstilling af et polypeptid i en sådan vært, plasmid, genetisk manipuleret industriel Bacillus-mikroorganisme og anvendelse af en sådan mikroorganisme DK169996B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP83201016 1983-07-06
EP83201016 1983-07-06
PCT/NL1984/000021 WO1985000382A1 (en) 1983-07-06 1984-07-06 Molecular cloning and expression in industrial microorganism species
NL8400021 1984-07-06

Publications (3)

Publication Number Publication Date
DK101385D0 true DK101385D0 (da) 1985-03-05
DK101385A DK101385A (da) 1985-03-05
DK169996B1 DK169996B1 (da) 1995-04-24

Family

ID=8190976

Family Applications (1)

Application Number Title Priority Date Filing Date
DK101385A DK169996B1 (da) 1983-07-06 1985-03-05 Fremgangsmåde til effektiv indføring af DNA i en industriel Bacillus-stammevært, fremgangsmåde til fremstilling af et polypeptid i en sådan vært, plasmid, genetisk manipuleret industriel Bacillus-mikroorganisme og anvendelse af en sådan mikroorganisme

Country Status (11)

Country Link
EP (1) EP0134048B2 (da)
JP (2) JP2669457B2 (da)
AU (1) AU570709B2 (da)
DE (1) DE3480411D1 (da)
DK (1) DK169996B1 (da)
ES (2) ES8608579A1 (da)
FI (1) FI85287C (da)
GR (1) GR82200B (da)
IE (1) IE58014B1 (da)
NZ (1) NZ208806A (da)
WO (1) WO1985000382A1 (da)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5624829A (en) * 1984-07-03 1997-04-29 Gist-Brocades, B.V. Transformed industrial bacillus strains and methods for making and using them
CA1311429C (en) * 1983-07-06 1992-12-15 Vasantha Nagarajan Vector for polypeptides in bacilli
EP0149241B1 (en) * 1983-12-28 1991-03-27 Agency Of Industrial Science And Technology Dna base sequence containing regions involved in the production and secretion of a protein, recombinant dna including the whole or a part of the dna base sequence, and method of producing proteins by use of the recombinant dna
JPS60188093A (ja) * 1984-03-09 1985-09-25 Teruhiko Beppu 枯草菌に於ける形質発現プラスミド
IE58099B1 (en) * 1984-06-06 1993-06-30 Cpc International Inc Amylase-negative, asporogenous mutant of bacillus subtilis useful as a host in a host-vector system
US4801537A (en) * 1984-06-08 1989-01-31 Genex Corporation Vector for expression of polypeptides in bacilli
JPH0616711B2 (ja) * 1985-09-27 1994-03-09 メルシャン株式会社 高温で自律増殖するプラスミド
US5024943A (en) * 1985-11-07 1991-06-18 Gist-Brocades Regulatory region cloning and analysis plasmid for bacillus
DK311186D0 (da) * 1986-06-30 1986-06-30 Novo Industri As Enzymer
PT86863B (pt) 1987-02-27 1992-05-29 Gist Brocades Nv Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos
EP0896062A3 (en) * 1987-02-27 1999-04-07 Genencor International, Inc. Transformation of alkalophilic bacillus strains
PT86864B (pt) * 1987-02-27 1992-05-29 Gist Brocades Nv Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
ATE166922T1 (de) * 1989-06-29 1998-06-15 Genencor Int Mutierte mikrobielle alpha-amylasen mit erhöhter thermischer, saurer und/oder alkylischer stabilität
DE4216246A1 (de) * 1992-05-16 1993-11-18 Solvay Enzymes Gmbh & Co Kg Einfaches Verfahren zur stabilen chromosomalen Genamplifikation
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US20050079573A1 (en) 1998-12-23 2005-04-14 Danisco A/S Proteins
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
CA2422748C (en) 2000-09-21 2011-08-09 Dsm N.V. Talaromyces xylanases
ES2301579T3 (es) 2000-12-07 2008-07-01 Dsm Ip Assets B.V. Prolil endoproteasa a partir de aspergillus niger.
DE60103174T2 (de) 2000-12-07 2005-05-12 Dsm Ip Assets B.V. Verfahren zur verhinderung oder verminderung der trübung in getränken
GB0116453D0 (en) 2001-07-05 2001-08-29 Imp College Innovations Ltd Method
EP1495128B1 (en) 2002-03-29 2014-05-07 Genencor International, Inc. Ehanced protein expression in bacillus
DK1511835T5 (da) 2002-06-07 2015-05-18 Dsm Ip Assets Bv Forbedret fremgangsmåde til forebyggelse eller reducering af uklarheder i drikkevarer
TWI328612B (en) 2002-07-25 2010-08-11 Dsm Ip Assets Bv Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12
US20100129862A1 (en) 2003-05-12 2010-05-27 Jones Brian E Novel lipolytic Enzyme lip1
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
CA2946614C (en) 2005-11-28 2021-01-26 Dsm Ip Assets B.V. Enzyme preparations yielding a clean taste
GB0600406D0 (en) 2006-01-10 2006-02-15 Univ Bath Crystal
NZ578882A (en) 2007-02-20 2012-01-12 Dsm Ip Assets Bv Sialidase from the fungus Penicilium chrysogenum
CA2680563A1 (en) 2007-03-12 2008-09-18 Danisco Us Inc. Modified proteases
WO2008113799A1 (en) 2007-03-22 2008-09-25 Dsm Ip Assets B.V. Novel lysyl oxidases
WO2008141281A1 (en) 2007-05-10 2008-11-20 Danisco Us Inc., Genencor Division A modified secretion system to increase expression of polypeptides in bacteria
GB0715751D0 (en) * 2007-08-13 2007-09-19 Tmo Renewables Ltd Thermophilic micro-organisms for ethanol production
DK2235176T3 (da) 2007-12-21 2017-09-25 Danisco Us Inc Forbedret proteinsfremstilling i bacillus
US9528114B2 (en) 2008-03-28 2016-12-27 Danisco Us Inc. Method for amplifying locus in bacterial cell
CN102414321A (zh) 2009-04-24 2012-04-11 丹尼斯科美国公司 具有修饰的原区的蛋白酶
AR076941A1 (es) 2009-06-11 2011-07-20 Danisco Us Inc Cepa de bacillus para una mayor produccion de proteina
EP3190183B1 (en) 2009-12-09 2019-07-10 Danisco US Inc. Compositions and methods comprising protease variants
WO2011101339A2 (en) 2010-02-18 2011-08-25 Dsm Ip Assets B.V. Fermentation broth and filtration filter cake and uses thereof
CN102858970B (zh) 2010-04-15 2017-07-21 丹尼斯科美国公司 包含变体蛋白酶的组合物和方法
PL2566960T3 (pl) 2010-05-06 2017-08-31 The Procter And Gamble Company Produkty konsumenckie z odmianami proteaz
WO2012007446A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Use of a mutarotase in the production of dried powders
WO2012007445A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Mutarotase in crystallization
EP3486319B1 (en) 2011-05-05 2022-11-30 Danisco US Inc. Compositions and methods comprising serine protease variants
JP5933688B2 (ja) 2011-05-05 2016-06-15 ザ プロクター アンド ギャンブル カンパニー セリンプロテアーゼ変異体を含む組成物及び方法
CN102296042B (zh) * 2011-08-26 2013-04-24 甘肃农业大学 地衣芽孢杆菌及用其制备凝乳酶冻干粉的方法
EP2751263A1 (en) 2011-08-31 2014-07-09 Danisco US Inc. Compositions and methods comprising a lipolytic enzyme variant
US20150017700A1 (en) 2011-12-22 2015-01-15 Danisco Us Inc. Compositions and methods comprising a lipolytic enzyme variant
CN104736700B (zh) 2012-10-12 2019-02-01 丹尼斯科美国公司 包含脂解酶变体的组合物和方法
CA2889864C (en) 2012-11-05 2023-02-28 Danisco Us Inc. Compositions and methods comprising thermolysin protease variants
US20150344858A1 (en) 2012-12-19 2015-12-03 Danisco Us Inc. Novel mannanase, compositions and methods of use thereof
EP4159854A1 (en) 2013-05-29 2023-04-05 Danisco US Inc Novel metalloproteases
EP3004314B1 (en) 2013-05-29 2018-06-20 Danisco US Inc. Novel metalloproteases
EP3882346A1 (en) 2013-05-29 2021-09-22 Danisco US Inc. Novel metalloproteases
US20160108387A1 (en) 2013-05-29 2016-04-21 Danisco Us Inc. Novel metalloproteases
MX2020001159A (es) 2013-07-19 2021-07-07 Danisco Us Inc Composiciones y metodos que comprenden una variante de enzima lipolitica.
BR112016005286A2 (pt) 2013-09-12 2017-09-12 Danisco Us Inc composições e métodos compreendendo variantes de protease do clado lg12
WO2015089447A1 (en) 2013-12-13 2015-06-18 Danisco Us Inc. Serine proteases of the bacillus gibsonii-clade
WO2015089441A1 (en) 2013-12-13 2015-06-18 Danisco Us Inc. Serine proteases of bacillus species
EP3089991B1 (en) 2013-12-31 2019-08-28 Danisco US Inc. Enhanced protein expression
CN106170546A (zh) 2014-03-21 2016-11-30 丹尼斯科美国公司 芽孢杆菌属的丝氨酸蛋白酶
DK3207129T3 (da) 2014-10-17 2020-02-24 Danisco Us Inc Serinproteaser af bacillus-arten
WO2016069544A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
CN107148472A (zh) 2014-10-27 2017-09-08 丹尼斯科美国公司 芽孢杆菌属物种的丝氨酸蛋白酶
EP3550017B1 (en) 2014-10-27 2021-07-14 Danisco US Inc. Serine proteases
US20170335306A1 (en) 2014-10-27 2017-11-23 Danisco Us Inc. Serine proteases
DK3212662T3 (da) 2014-10-27 2020-07-20 Danisco Us Inc Serinproteaser
KR102588719B1 (ko) 2014-12-16 2023-10-12 다니스코 유에스 인크. 향상된 단백질 발현
WO2016100128A1 (en) 2014-12-19 2016-06-23 Danisco Us Inc Enhanced protein expression
EP3611259A1 (en) 2015-03-12 2020-02-19 Danisco US Inc. Compositions and methods comprising lg12-clade protease variants
EP4219704A3 (en) 2015-05-13 2023-08-23 Danisco US Inc Aprl-clade protease variants and uses thereof
EP4234693A3 (en) 2015-06-17 2023-11-01 Danisco US Inc Bacillus gibsonii-clade serine proteases
JP7134629B2 (ja) 2015-06-17 2022-09-12 ダニスコ・ユーエス・インク 改変プロペプチド領域を備えるプロテアーゼ
WO2017192692A1 (en) 2016-05-03 2017-11-09 Danisco Us Inc Protease variants and uses thereof
WO2017192300A1 (en) 2016-05-05 2017-11-09 Danisco Us Inc Protease variants and uses thereof
US11661567B2 (en) 2016-05-31 2023-05-30 Danisco Us Inc. Protease variants and uses thereof
EP4151726A1 (en) 2016-06-17 2023-03-22 Danisco US Inc Protease variants and uses thereof
US11946081B2 (en) 2016-12-21 2024-04-02 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
EP3559227A1 (en) 2016-12-21 2019-10-30 Danisco US Inc. Protease variants and uses thereof
US20200354708A1 (en) 2017-11-29 2020-11-12 Danisco Us Inc. Subtilisin variants having improved stability
WO2019245705A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
EP3810767A1 (en) 2018-06-19 2021-04-28 Danisco US Inc. Subtilisin variants
EP3833731A1 (en) 2018-08-30 2021-06-16 Danisco US Inc. Compositions comprising a lipolytic enzyme variant and methods of use thereof
EP3887515A1 (en) 2018-11-28 2021-10-06 Danisco US Inc. Subtilisin variants having improved stability
EP3976776A1 (en) 2019-05-24 2022-04-06 Danisco US Inc. Subtilisin variants and methods of use
EP4090727A1 (en) 2020-01-13 2022-11-23 Danisco US Inc. Compositions comprising a lipolytic enzyme variant and methods of use thereof
CN116323935A (zh) 2020-08-27 2023-06-23 丹尼斯科美国公司 用于清洁的酶和酶组合物
CN117616120A (zh) 2021-06-30 2024-02-27 丹尼斯科美国公司 变体脂肪酶及其用途
WO2023034486A2 (en) 2021-09-03 2023-03-09 Danisco Us Inc. Laundry compositions for cleaning
US20230365897A1 (en) 2021-12-16 2023-11-16 The Procter & Gamble Company Fabric and home care composition including a protease
WO2023114939A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
US20240166973A1 (en) 2021-12-16 2024-05-23 The Procter & Gamble Company Automatic dishwashing composition comprising a protease
WO2023114932A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023114936A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
WO2024050343A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Subtilisin variants and methods related thereto
WO2024050346A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Detergent compositions and methods related thereto
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO159863C (no) * 1980-01-07 1989-02-15 Univ Rochester Fremgangsm te for fremstilling og seleksjon av en rant bakteriofag som inneholder et genetisk fragment og koder for alfa-amylase, egnet for bruk i heterolog transformering av en bacillus-verts-mikroorganisme.
IL61982A (en) * 1980-02-15 1984-01-31 Cpc International Inc Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes
ZA81424B (en) * 1980-02-15 1982-02-24 Cpc International Inc Genetically engineered microorganisms for massive production of amylolytic enzymes and process for preparing same
JPS56137896A (en) * 1980-03-10 1981-10-28 Cetus Corp Genetic recombination gram positive bacteria , production thereof and protein for mammal produced by said gram positive bacteria
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
CA1206108A (en) * 1981-03-06 1986-06-17 Shuichi Aiba Process for transforming microorganism by means of plasmid introduction
BR8205954A (pt) * 1981-10-14 1983-09-13 Unilever Nv Sequencia de dna,plasmidio recombinante,cultura bacteriana e microorganismos
JPS5889194A (ja) * 1981-11-24 1983-05-27 Ajinomoto Co Inc 微生物によるｌ−トリプトフアンの製造法
JPS58107192A (ja) * 1981-12-18 1983-06-25 Ajinomoto Co Inc 発酵法によるｌ−ヒスチジンの製造法

Also Published As

Publication number Publication date
DE3480411D1 (en) 1989-12-14
EP0134048B1 (en) 1989-11-08
ES534102A0 (es) 1986-06-16
JP2669457B2 (ja) 1997-10-27
JPH06189783A (ja) 1994-07-12
AU570709B2 (en) 1988-03-24
NZ208806A (en) 1988-07-28
DK101385A (da) 1985-03-05
FI85287C (fi) 1992-03-25
WO1985000382A1 (en) 1985-01-31
AU3151084A (en) 1985-02-07
DK169996B1 (da) 1995-04-24
ES8609467A1 (es) 1986-08-01
IE58014B1 (en) 1993-06-16
EP0134048A1 (en) 1985-03-13
EP0134048B2 (en) 1996-08-14
GR82200B (da) 1984-12-13
FI85287B (fi) 1991-12-13
JP2664860B2 (ja) 1997-10-22
ES545256A0 (es) 1986-08-01
JPS60501738A (ja) 1985-10-17
FI850845A0 (fi) 1985-03-01
FI850845L (fi) 1985-03-01
ES8608579A1 (es) 1986-06-16
IE841726L (en) 1985-01-06

Similar Documents

Publication Publication Date Title
DK101385D0 (da) Molekylaer kloning og ekspression i industrielle mikroorganismearter
DK241581A (da) Thiophensulfonamider og deres anvendelse i herbicider
DK41484A (da) Beta-phenethanolaminer og deres anvendelse
DK162147C (da) Traebeskyttelsesmiddel og anvendelse heraf
NO810200L (no) V anriket kullprodukt og fremgangsmaate ved fremstilling dera
DK431384D0 (da) Enzymprodukter og deres anvendelse ved saceharificering
ES534446A0 (es) Perfeccionamientos en fonocardiografos y electrocardiografos
DK44084A (da) Klonings- og ekspressionsvektor og gaer transformeret dermed
DK141494A (da) Forbedringer af og i relation til kødbehandling
MX162354A (es) Mejoras en conjunto adsorbedor
ES536840A0 (es) Perfeccionamientos en supercalandrias con eliminacion de pellizcado.
ES537049A0 (es) Perfeccionamientos en las valvulas reductoras
DK40581A (da) Hydro-haerdelige praeparater og deres anvendelse i belaegninger impraegneringsmidler og adhaesiver
DK349884D0 (da) Forbedringer i fremdrivningsanlaeggene til dampturbinedrevne skibe
DK92881A (da) Sav og savbord herfor
DK406384D0 (da) Imidazobenzodiazepinderivater og disses anvendelse
DK140684D0 (da) Phenethanolaminer og deres anvendelse
DK162607C (da) Azopigmentpraeparater og deres anvendelse
DK394385A (da) Sulfonylguanidinopyrimidinderivater og deres anvendelse i herbicider
ES533623A0 (es) Perfeccionamientos en somieres
DK116183D0 (da) Beskyttelsesbehandling af traevaerk i monterede vinduer og lignende
DK393885A (da) Sulfoguanidinotriazinderivater og deres anvendelse i herbicider
DK157389C (da) Intrauteringspessar og indfoeringsvaerktoej hertil
BR6300984U (pt) Aperfeicoamento em mamadeira anti-colica
KR840007295U (ko) 귀이개및 이쑤시게를 겸한 성냥

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired