DK0999832T3 - Præparat omfattende L-carnitin eller en alkanoyl-L-carnitin og langkædede alkanoler - Google Patents

Præparat omfattende L-carnitin eller en alkanoyl-L-carnitin og langkædede alkanoler

Info

Publication number
DK0999832T3
DK0999832T3 DK98932504T DK98932504T DK0999832T3 DK 0999832 T3 DK0999832 T3 DK 0999832T3 DK 98932504 T DK98932504 T DK 98932504T DK 98932504 T DK98932504 T DK 98932504T DK 0999832 T3 DK0999832 T3 DK 0999832T3
Authority
DK
Denmark
Prior art keywords
carnitine
alkanoyl
composition
chain alkanols
long chain
Prior art date
Application number
DK98932504T
Other languages
Danish (da)
English (en)
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK0999832T3 publication Critical patent/DK0999832T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
DK98932504T 1997-08-01 1998-07-09 Præparat omfattende L-carnitin eller en alkanoyl-L-carnitin og langkædede alkanoler DK0999832T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97RM000487A IT1294227B1 (it) 1997-08-01 1997-08-01 Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
EP98932504A EP0999832B1 (en) 1997-08-01 1998-07-09 Composition comprising l-carnitine or an alkanoyl l-carnitine and long-chain alkanols
PCT/IT1998/000190 WO1999006039A1 (en) 1997-08-01 1998-07-09 Composition comprising l-carnitine or an alkanoyl l-carnitine and long-chain alkanols

Publications (1)

Publication Number Publication Date
DK0999832T3 true DK0999832T3 (da) 2005-01-17

Family

ID=11405212

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98932504T DK0999832T3 (da) 1997-08-01 1998-07-09 Præparat omfattende L-carnitin eller en alkanoyl-L-carnitin og langkædede alkanoler

Country Status (16)

Country Link
US (1) US6328998B1 (ko)
EP (1) EP0999832B1 (ko)
JP (1) JP4295429B2 (ko)
KR (1) KR100530878B1 (ko)
AT (1) ATE277611T1 (ko)
AU (1) AU741363B2 (ko)
CA (1) CA2295746C (ko)
DE (1) DE69826674T2 (ko)
DK (1) DK0999832T3 (ko)
ES (1) ES2229514T3 (ko)
HK (1) HK1028547A1 (ko)
IT (1) IT1294227B1 (ko)
NZ (1) NZ501967A (ko)
PT (1) PT999832E (ko)
SI (1) SI0999832T1 (ko)
WO (1) WO1999006039A1 (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1306178B1 (it) 1999-07-27 2001-05-30 Sigma Tau Ind Farmaceuti Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da
IT1306722B1 (it) * 1999-10-08 2001-10-02 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento di disfunzionicircolatorie, comprendente derivati della l-carnitina ed estratti di
US7214394B2 (en) * 2002-05-31 2007-05-08 Archer-Daniels-Midland Company Policosanol compositions, extraction from novel sources, and uses thereof
US20060166951A1 (en) * 2002-05-31 2006-07-27 Archer-Daniels-Midland Company Compositions and methods for sterol isolation and purification
JP4533134B2 (ja) 2002-06-10 2010-09-01 エラン ファーマ インターナショナル，リミティド ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ
ATE439127T1 (de) * 2002-06-17 2009-08-15 Medestea Res & Production S P Langkettige ungesättigte sauerstoffhaltige verbindungen und deren verwendung im therapeutischen, kosmetischen und diätetischen bereich
US20090196914A1 (en) * 2002-11-14 2009-08-06 Optime Therapeutics, Inc. Liposomal l-carnitine
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
ITRM20040327A1 (it) * 2004-07-01 2004-10-01 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
US7615641B2 (en) * 2004-07-20 2009-11-10 Sino Pharmaceuticals Corporation Long chain aliphatic alcohol derivatives and methods of making and using same
US20070087975A1 (en) * 2005-10-17 2007-04-19 Sigma-Tau Industrie Farmaceutiche Riunite Spa Compound useful for the prevention and treatment of left ventricular hypertrophy in dialysed patients
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
CN111295187A (zh) 2017-08-14 2020-06-16 胺细拉健康公司 用于治疗肝脏疾病的氨基酸组合物
EP3810123A1 (en) 2018-06-20 2021-04-28 Axcella Health Inc. Compositions and methods for the treatment of fat infiltration in muscle

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903558C2 (de) * 1978-02-03 1994-09-01 Sigma Tau Ind Farmaceuti Verwendung von L-Carnitin
JPS6299323A (ja) * 1985-10-25 1987-05-08 Yoshihide Hagiwara 高脂血症剤
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
US5135956A (en) * 1988-10-18 1992-08-04 The Regents Of The University Of California Method of using cytoprotective alcohols to treat neural disease and neural injury
DE69026496D1 (de) * 1989-10-13 1996-05-15 Neurofit Analoge von vitamin a und ihre verwendung, insbesondere als cytotrophische und cytoprotective substanzen sowie diese substanzen enthaltende arzneimittel
JPH05103596A (ja) * 1991-10-11 1993-04-27 Yukio Yanagimoto 陸上動物用体力増強剤及び陸上動物用飼料
JPH05103629A (ja) * 1991-10-11 1993-04-27 Yukio Yanagimoto 体力増強剤
CU22229A1 (es) * 1992-09-29 1996-01-31 Dalmer Lab Sa Policosanol, una mezcla de alcoholes alifaticos primarios superiores para hipergregabilidad plaquetaria, los accidentes isquemicos, trombosis e incluso efectividad contra ulceras gastricas quimicamente inducidas y su proceso de obtencion de la caña de azucar. el tratamiento de complicaciones ateroscleroticas tales como la
JPH05310563A (ja) * 1992-05-15 1993-11-22 Nippon Oil & Fats Co Ltd カルシトニン産生増強剤
JPH0825891B2 (ja) * 1993-06-25 1996-03-13 株式会社薬理学中央研究所 脱脂米胚芽由来のリパーゼインヒビター
US5560928A (en) * 1995-06-23 1996-10-01 Defelice; Stephen L. Nutritional and/or dietary composition and method of using the same
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1283967B1 (it) * 1996-03-29 1998-05-07 Sigma Tau Ind Farmaceuti Uso di l-carnitina o derivati della l-carnitina ed antiossidanti nella prevenzione e trattamento di patologie derivanti da danni ossidativi

Also Published As

Publication number Publication date
DE69826674D1 (de) 2004-11-04
PT999832E (pt) 2004-12-31
EP0999832A1 (en) 2000-05-17
EP0999832B1 (en) 2004-09-29
ATE277611T1 (de) 2004-10-15
WO1999006039A1 (en) 1999-02-11
HK1028547A1 (en) 2001-02-23
JP2001511447A (ja) 2001-08-14
AU741363B2 (en) 2001-11-29
KR20010022449A (ko) 2001-03-15
SI0999832T1 (en) 2004-12-31
CA2295746A1 (en) 1999-02-11
US6328998B1 (en) 2001-12-11
ITRM970487A1 (it) 1999-02-01
CA2295746C (en) 2007-11-20
NZ501967A (en) 2001-09-28
IT1294227B1 (it) 1999-03-24
KR100530878B1 (ko) 2005-11-23
ES2229514T3 (es) 2005-04-16
DE69826674T2 (de) 2005-02-24
AU8240798A (en) 1999-02-22
JP4295429B2 (ja) 2009-07-15

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