DK0946566T3 - Prodrugformer og camptothecinanaloger og deres anvendelse som lægemidler - Google Patents

Prodrugformer og camptothecinanaloger og deres anvendelse som lægemidler

Info

Publication number
DK0946566T3
DK0946566T3 DK97950235T DK97950235T DK0946566T3 DK 0946566 T3 DK0946566 T3 DK 0946566T3 DK 97950235 T DK97950235 T DK 97950235T DK 97950235 T DK97950235 T DK 97950235T DK 0946566 T3 DK0946566 T3 DK 0946566T3
Authority
DK
Denmark
Prior art keywords
drugs
prodrug forms
camptothecin analogues
camptothecin
analogues
Prior art date
Application number
DK97950235T
Other languages
Danish (da)
English (en)
Inventor
Dennis Bigg
Olivier Lavergne
Jerry Harnett
Alain Rolland
Anne-Marie Liberatore
Christophe Lanco
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9615775A external-priority patent/FR2757515B1/fr
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of DK0946566T3 publication Critical patent/DK0946566T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK97950235T 1996-12-20 1997-12-05 Prodrugformer og camptothecinanaloger og deres anvendelse som lægemidler DK0946566T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9615775A FR2757515B1 (fr) 1996-12-20 1996-12-20 Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR9615945 1996-12-24
PCT/FR1997/002217 WO1998028304A1 (fr) 1996-12-20 1997-12-05 Formes prodrogues et analogues de la camptothecine, leur application comme medicaments

Publications (1)

Publication Number Publication Date
DK0946566T3 true DK0946566T3 (da) 2004-03-15

Family

ID=26233188

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97950235T DK0946566T3 (da) 1996-12-20 1997-12-05 Prodrugformer og camptothecinanaloger og deres anvendelse som lægemidler

Country Status (24)

Country Link
EP (1) EP0946566B1 (ja)
JP (1) JP3576174B2 (ja)
KR (1) KR100516873B1 (ja)
CN (1) CN1090634C (ja)
AR (1) AR005849A1 (ja)
AT (1) ATE253582T1 (ja)
AU (1) AU734512B2 (ja)
BR (1) BR9713977B1 (ja)
CA (1) CA2275345C (ja)
CZ (1) CZ299794B6 (ja)
DE (1) DE69726007T2 (ja)
DK (1) DK0946566T3 (ja)
ES (1) ES2206760T3 (ja)
HK (1) HK1024694A1 (ja)
HU (1) HUP0001385A3 (ja)
IL (2) IL129892A0 (ja)
MY (1) MY122042A (ja)
NO (1) NO324973B1 (ja)
NZ (1) NZ335938A (ja)
PL (1) PL188109B1 (ja)
PT (1) PT946566E (ja)
TW (1) TW410224B (ja)
UA (1) UA57757C2 (ja)
WO (1) WO1998028304A1 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (fr) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
DE69932649T2 (de) * 1998-09-02 2007-08-09 Pharmagenesis, Inc., Palo Alto Triptolid-Prodrugs mit hoher Wasserlöslichkeit
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
FR2801309B1 (fr) * 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6350756B1 (en) 2001-01-18 2002-02-26 California Pacific Medical Center Camptothecin derivatives
US6403604B1 (en) 2001-03-01 2002-06-11 California Pacific Medical Center Nitrogen-based camptothecin derivatives
US6855720B2 (en) 2001-03-01 2005-02-15 California Pacific Medical Center Nitrogen-based camptothecin derivatives
AU2003225642A1 (en) * 2002-03-01 2003-09-16 Fluorous Techonologies Inc Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs
AU2003243380A1 (en) 2002-06-03 2003-12-19 California Pacific Medical Center Nitrogen-based homo-camptothecin derivatives
EP1694684B1 (en) * 2003-12-17 2011-08-03 Bionumerik Pharmaceuticals, Inc. Process for making camptothecin derivatives
CN1964979B (zh) * 2004-04-09 2011-07-27 中外制药株式会社 新颖的水溶性前药
ITRM20040288A1 (it) * 2004-06-11 2004-09-11 Sigma Tau Ind Farmaceuti Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero.
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
FR2892417B1 (fr) * 2005-10-24 2010-10-22 Servier Lab Nouveaux composes aminoesterifies a cycle e hydrocarbone a sept chainons analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2892418B1 (fr) * 2005-10-24 2010-10-22 Servier Lab Nouveaux composes aminoesterifies a cycle e hydrocarbone a six chainons analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN100465175C (zh) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-位取代高喜树碱类化合物及作为药物的用途
CN100441580C (zh) * 2006-07-14 2008-12-10 中山大学 喹啉二酮衍生物及其在制备抗菌药物中的应用
CN102746314B (zh) * 2011-04-18 2016-07-06 华东师范大学 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
CN117164601A (zh) * 2022-06-02 2023-12-05 华东师范大学 一种高喜树碱类小分子及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391745A (en) * 1992-07-23 1995-02-21 Sloan-Kettering Institute For Cancer Research Methods of preparation of camptothecin analogs
RU2164515C2 (ru) * 1995-06-21 2001-03-27 Сосьете де Консей де Решерш э Д'Аппликасьон Сьентифик (СКРАС) Соединения камптотецина, способы их получения, промежуточные соединения и терапевтические композиции

Also Published As

Publication number Publication date
EP0946566B1 (fr) 2003-11-05
AR005849A1 (es) 1999-07-21
WO1998028304A1 (fr) 1998-07-02
ES2206760T3 (es) 2004-05-16
DE69726007T2 (de) 2004-06-03
AU5326498A (en) 1998-07-17
CA2275345A1 (fr) 1998-07-02
IL129892A (en) 2007-09-20
NZ335938A (en) 2000-04-28
CN1090634C (zh) 2002-09-11
NO324973B1 (no) 2008-01-14
PL334092A1 (en) 2000-01-31
MY122042A (en) 2006-03-31
NO992997L (no) 1999-08-18
JP2001506270A (ja) 2001-05-15
PT946566E (pt) 2004-03-31
BR9713977A (pt) 2000-04-11
TW410224B (en) 2000-11-01
UA57757C2 (uk) 2003-07-15
AU734512B2 (en) 2001-06-14
JP3576174B2 (ja) 2004-10-13
ATE253582T1 (de) 2003-11-15
HUP0001385A3 (en) 2002-12-28
BR9713977B1 (pt) 2010-06-29
IL129892A0 (en) 2000-02-29
CZ209299A3 (cs) 1999-09-15
DE69726007D1 (de) 2003-12-11
HK1024694A1 (en) 2000-10-20
CZ299794B6 (cs) 2008-11-26
HUP0001385A2 (hu) 2000-10-28
CA2275345C (fr) 2010-01-26
KR100516873B1 (ko) 2005-09-26
KR20000062260A (ko) 2000-10-25
NO992997D0 (no) 1999-06-18
EP0946566A1 (fr) 1999-10-06
CN1241192A (zh) 2000-01-12
PL188109B1 (pl) 2004-12-31

Similar Documents

Publication Publication Date Title
NO20002486D0 (no) Sykliske aminderivater og deres anvendelse som legemidler
DK0946566T3 (da) Prodrugformer og camptothecinanaloger og deres anvendelse som lægemidler
NO985977D0 (no) Spiro-piperidinderivater og deres anvendelse som terapeutiske midler
NO991815D0 (no) Oksadiazoler, fremgangsmÕter for deres fremstilling og deres anvendelse som medikamenter
DK0869126T3 (da) Dithiolanderivater, deres fremstilling og deres terapeutiske virkning
DK1204649T3 (da) Arylmethylcarbonylaminothiazolderivater og deres anvendelse som antitumormidler
NO20014702L (no) Diarylderivater og deres anvendelse som medikamenter
NO2011007I1 (no) Ticagrelor eller et farmasøytisk akseptabelt salt derav
DK0906292T3 (da) Triazolylmercaptider og deres anvendelse som mikrobicider
NO20002359L (no) Adenosinderivater og farmasoytisk sammensetning inneholdende derivatene
NO996133D0 (no) Olje-i-vann-vaksinesammensetninger
DK1095025T3 (da) Benzimidazoler, deres fremstilling og deres anvendelse som lægemidler
NO971811D0 (no) Bicykliske tetrahydropyrazolopyridiner og deres anvendelse som legemidler
NO20025357D0 (no) Antranylamider og deres anvendelse som legemidler
NO20005146D0 (no) Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter
NO20003067D0 (no) Antipicornavirus-forbindelser og fremgangsmÕter for deres anvendelse og fremstilling
NO984761D0 (no) Aminoisokinoliner og aminotienopyridinderivater og deres anvendelse som antiinflammatoriske midler
DK1235777T3 (da) Vitamin D-analoger
NO993467D0 (no) Granuler som innbefatter klavulanat og en eller flere eksipienter
NO995683D0 (no) Vitamin D analoger og deres neuronale effekter
NO20000366D0 (no) O-substituerte hydroksycoumaranon-derivater som anti-tumor- og antimetastase-midler
NO982874D0 (no) Farmas°ytiske preparater med vitamin D-analoger
NO995513L (no) N-triazolyl-2-indolkarboksamider og deres anvendelse som CCK-
IS6723A (is) 10-arýl-11H-bensó[b]flúorenafleiður og hliðstæðurtil lyfjanotkunar
DK0764157T3 (da) Benzopyraner og deres anvendelse som terapeutiske midler