IL129892A0 - Prodrug forms and new analogues of camptothecin and their use as medicaments - Google Patents

Prodrug forms and new analogues of camptothecin and their use as medicaments

Info

Publication number
IL129892A0
IL129892A0 IL12989297A IL12989297A IL129892A0 IL 129892 A0 IL129892 A0 IL 129892A0 IL 12989297 A IL12989297 A IL 12989297A IL 12989297 A IL12989297 A IL 12989297A IL 129892 A0 IL129892 A0 IL 129892A0
Authority
IL
Israel
Prior art keywords
camptothecin
medicaments
prodrug forms
new analogues
analogues
Prior art date
Application number
IL12989297A
Other languages
English (en)
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9615775A external-priority patent/FR2757515B1/fr
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of IL129892A0 publication Critical patent/IL129892A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL12989297A 1996-12-20 1997-12-05 Prodrug forms and new analogues of camptothecin and their use as medicaments IL129892A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9615775A FR2757515B1 (fr) 1996-12-20 1996-12-20 Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR9615945 1996-12-24
PCT/FR1997/002217 WO1998028304A1 (fr) 1996-12-20 1997-12-05 Formes prodrogues et analogues de la camptothecine, leur application comme medicaments

Publications (1)

Publication Number Publication Date
IL129892A0 true IL129892A0 (en) 2000-02-29

Family

ID=26233188

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12989297A IL129892A0 (en) 1996-12-20 1997-12-05 Prodrug forms and new analogues of camptothecin and their use as medicaments
IL129892A IL129892A (en) 1996-12-20 1999-05-11 History of Homologues of Campacetcin, their Preparation and Pharmaceutical Preparations Containing Them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL129892A IL129892A (en) 1996-12-20 1999-05-11 History of Homologues of Campacetcin, their Preparation and Pharmaceutical Preparations Containing Them

Country Status (24)

Country Link
EP (1) EP0946566B1 (xx)
JP (1) JP3576174B2 (xx)
KR (1) KR100516873B1 (xx)
CN (1) CN1090634C (xx)
AR (1) AR005849A1 (xx)
AT (1) ATE253582T1 (xx)
AU (1) AU734512B2 (xx)
BR (1) BR9713977B1 (xx)
CA (1) CA2275345C (xx)
CZ (1) CZ299794B6 (xx)
DE (1) DE69726007T2 (xx)
DK (1) DK0946566T3 (xx)
ES (1) ES2206760T3 (xx)
HK (1) HK1024694A1 (xx)
HU (1) HUP0001385A3 (xx)
IL (2) IL129892A0 (xx)
MY (1) MY122042A (xx)
NO (1) NO324973B1 (xx)
NZ (1) NZ335938A (xx)
PL (1) PL188109B1 (xx)
PT (1) PT946566E (xx)
TW (1) TW410224B (xx)
UA (1) UA57757C2 (xx)
WO (1) WO1998028304A1 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (fr) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
AU764123B2 (en) * 1998-09-02 2003-08-07 Pharmagenesis, Inc. Triptolide prodrugs having high aqueous solubility
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
FR2801309B1 (fr) * 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6350756B1 (en) 2001-01-18 2002-02-26 California Pacific Medical Center Camptothecin derivatives
US6403604B1 (en) 2001-03-01 2002-06-11 California Pacific Medical Center Nitrogen-based camptothecin derivatives
US6855720B2 (en) 2001-03-01 2005-02-15 California Pacific Medical Center Nitrogen-based camptothecin derivatives
WO2003074524A2 (en) * 2002-03-01 2003-09-12 University Of Pittsburgh Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs
AU2003243380A1 (en) 2002-06-03 2003-12-19 California Pacific Medical Center Nitrogen-based homo-camptothecin derivatives
ATE518870T1 (de) * 2003-12-17 2011-08-15 Bionumerik Pharmaceuticals Inc Verfahren zur herstellung von camptothecin- derivaten
BRPI0509732A (pt) * 2004-04-09 2007-09-25 Chugai Pharmaceutical Co Ltd pró-fármaco solúvel em água, composição farmacêutica, agente terapêutico, agente antifungo e uso do referido pró-fármaco
ITRM20040288A1 (it) * 2004-06-11 2004-09-11 Sigma Tau Ind Farmaceuti Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero.
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
FR2892417B1 (fr) * 2005-10-24 2010-10-22 Servier Lab Nouveaux composes aminoesterifies a cycle e hydrocarbone a sept chainons analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2892418B1 (fr) * 2005-10-24 2010-10-22 Servier Lab Nouveaux composes aminoesterifies a cycle e hydrocarbone a six chainons analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN100465175C (zh) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-位取代高喜树碱类化合物及作为药物的用途
CN100441580C (zh) * 2006-07-14 2008-12-10 中山大学 喹啉二酮衍生物及其在制备抗菌药物中的应用
CN102746314B (zh) * 2011-04-18 2016-07-06 华东师范大学 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
WO2023232145A1 (zh) * 2022-06-02 2023-12-07 华东师范大学 一种高喜树碱类小分子及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391745A (en) * 1992-07-23 1995-02-21 Sloan-Kettering Institute For Cancer Research Methods of preparation of camptothecin analogs
JP3576171B2 (ja) * 1995-06-21 2004-10-13 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・（エス．セー．エール．アー．エス） カンプトテシンの新規な同族体、その製造方法、その医薬としての用途及びこれを含有する医薬組成物

Also Published As

Publication number Publication date
AU5326498A (en) 1998-07-17
PT946566E (pt) 2004-03-31
HK1024694A1 (en) 2000-10-20
JP3576174B2 (ja) 2004-10-13
NO992997L (no) 1999-08-18
CZ299794B6 (cs) 2008-11-26
KR100516873B1 (ko) 2005-09-26
CN1090634C (zh) 2002-09-11
CN1241192A (zh) 2000-01-12
MY122042A (en) 2006-03-31
NZ335938A (en) 2000-04-28
ES2206760T3 (es) 2004-05-16
BR9713977B1 (pt) 2010-06-29
EP0946566A1 (fr) 1999-10-06
CA2275345A1 (fr) 1998-07-02
BR9713977A (pt) 2000-04-11
UA57757C2 (uk) 2003-07-15
KR20000062260A (ko) 2000-10-25
AU734512B2 (en) 2001-06-14
AR005849A1 (es) 1999-07-21
DK0946566T3 (da) 2004-03-15
HUP0001385A3 (en) 2002-12-28
TW410224B (en) 2000-11-01
PL334092A1 (en) 2000-01-31
ATE253582T1 (de) 2003-11-15
WO1998028304A1 (fr) 1998-07-02
NO324973B1 (no) 2008-01-14
PL188109B1 (pl) 2004-12-31
DE69726007T2 (de) 2004-06-03
JP2001506270A (ja) 2001-05-15
NO992997D0 (no) 1999-06-18
HUP0001385A2 (hu) 2000-10-28
IL129892A (en) 2007-09-20
DE69726007D1 (de) 2003-12-11
CA2275345C (fr) 2010-01-26
EP0946566B1 (fr) 2003-11-05
CZ209299A3 (cs) 1999-09-15

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed