ATE518870T1 - Verfahren zur herstellung von camptothecin- derivaten - Google Patents

Verfahren zur herstellung von camptothecin- derivaten

Info

Publication number
ATE518870T1
ATE518870T1 AT04800503T AT04800503T ATE518870T1 AT E518870 T1 ATE518870 T1 AT E518870T1 AT 04800503 T AT04800503 T AT 04800503T AT 04800503 T AT04800503 T AT 04800503T AT E518870 T1 ATE518870 T1 AT E518870T1
Authority
AT
Austria
Prior art keywords
camptothecin
producing
derivatives
camptothecine
camptothecine derivatives
Prior art date
Application number
AT04800503T
Other languages
English (en)
Inventor
Ye Wu
Kesavaram Narkunan
Jianyan Wang
Harry Kochat
Original Assignee
Bionumerik Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bionumerik Pharmaceuticals Inc filed Critical Bionumerik Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE518870T1 publication Critical patent/ATE518870T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/0825Preparations of compounds not comprising Si-Si or Si-cyano linkages
    • C07F7/083Syntheses without formation of a Si-C bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04800503T 2003-12-17 2004-11-01 Verfahren zur herstellung von camptothecin- derivaten ATE518870T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53015303P 2003-12-17 2003-12-17
PCT/US2004/036192 WO2005061517A1 (en) 2003-12-17 2004-11-01 Process for making camptothecin derivatives

Publications (1)

Publication Number Publication Date
ATE518870T1 true ATE518870T1 (de) 2011-08-15

Family

ID=34710157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04800503T ATE518870T1 (de) 2003-12-17 2004-11-01 Verfahren zur herstellung von camptothecin- derivaten

Country Status (10)

Country Link
EP (1) EP1694684B1 (de)
JP (1) JP4701185B2 (de)
CN (1) CN100425611C (de)
AT (1) ATE518870T1 (de)
AU (1) AU2004303777B2 (de)
CA (1) CA2548543C (de)
DK (1) DK1694684T3 (de)
MX (1) MXPA06006711A (de)
WO (1) WO2005061517A1 (de)
ZA (1) ZA200604758B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112225745B (zh) * 2020-11-16 2021-10-12 烟台大学 一种具有抗肿瘤活性的异片螺素类化合物、制备方法及用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136978A (en) * 1993-06-30 2000-10-24 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6150343A (en) 1993-06-30 2000-11-21 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
KR960029336A (ko) * 1995-01-09 1996-08-17 김충환 캄토테신 유도체, 그의 제조 방법 및 이를 함유하는 항암제
CN1107678C (zh) 1996-08-19 2003-05-07 比奥纽默里克药物公司 高亲脂性喜树碱衍生物,其制备方法及其用途
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
US6723849B1 (en) 2002-10-25 2004-04-20 Bionumerik Pharmaceuticals, Inc. Process for making camptothecin derivatives

Also Published As

Publication number Publication date
EP1694684A4 (de) 2009-06-03
EP1694684A1 (de) 2006-08-30
CN1894257A (zh) 2007-01-10
AU2004303777A1 (en) 2005-07-07
AU2004303777B2 (en) 2010-06-10
ZA200604758B (en) 2007-10-31
MXPA06006711A (es) 2006-08-31
WO2005061517A1 (en) 2005-07-07
CA2548543C (en) 2012-01-03
JP4701185B2 (ja) 2011-06-15
EP1694684B1 (de) 2011-08-03
CA2548543A1 (en) 2005-07-07
JP2007514779A (ja) 2007-06-07
CN100425611C (zh) 2008-10-15
DK1694684T3 (da) 2011-11-21

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