DE602004009962D1 - Verfahren zur herstellung von substituierten 5-aminopyrazoloä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidinen - Google Patents

Verfahren zur herstellung von substituierten 5-aminopyrazoloä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidinen

Info

Publication number
DE602004009962D1
DE602004009962D1 DE602004009962T DE602004009962T DE602004009962D1 DE 602004009962 D1 DE602004009962 D1 DE 602004009962D1 DE 602004009962 T DE602004009962 T DE 602004009962T DE 602004009962 T DE602004009962 T DE 602004009962T DE 602004009962 D1 DE602004009962 D1 DE 602004009962D1
Authority
DE
Germany
Prior art keywords
cypyrimidines
preparing substituted
substituted
preparing
triazolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004009962T
Other languages
English (en)
Other versions
DE602004009962T2 (de
Inventor
Shen-Chun Kuo
Loc Thanh Tran
Pengyi Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE602004009962D1 publication Critical patent/DE602004009962D1/de
Application granted granted Critical
Publication of DE602004009962T2 publication Critical patent/DE602004009962T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE602004009962T 2003-12-01 2004-11-29 Verfahren zur herstellung von substituierten 5-aminopyrazoloä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidinen Active DE602004009962T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52592503P 2003-12-01 2003-12-01
US525925P 2003-12-01
PCT/US2004/039847 WO2005054245A2 (en) 2003-12-01 2004-11-29 Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines

Publications (2)

Publication Number Publication Date
DE602004009962D1 true DE602004009962D1 (de) 2007-12-20
DE602004009962T2 DE602004009962T2 (de) 2008-08-28

Family

ID=34652398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004009962T Active DE602004009962T2 (de) 2003-12-01 2004-11-29 Verfahren zur herstellung von substituierten 5-aminopyrazoloä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidinen

Country Status (8)

Country Link
US (3) US7235659B2 (de)
EP (1) EP1689749B1 (de)
JP (1) JP2007513091A (de)
AT (1) ATE377599T1 (de)
CA (1) CA2547248A1 (de)
DE (1) DE602004009962T2 (de)
ES (1) ES2293380T3 (de)
WO (1) WO2005054245A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI288137B (en) * 2000-05-26 2007-10-11 Schering Corp Adenosine A2a receptor antagonists
DK1678182T3 (da) * 2003-10-28 2007-06-04 Schering Corp Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner
ATE556712T1 (de) 2005-06-07 2012-05-15 Kyowa Hakko Kirin Co Ltd A2a antagonisten zur behandlung von motorischen störungen
ES2273599B1 (es) 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
US8188098B2 (en) 2008-05-19 2012-05-29 Hoffmann-La Roche Inc. GPR119 receptor agonists
CA2756871A1 (en) 2009-03-31 2010-10-07 Arqule, Inc. Substituted heterocyclic compounds
WO2012127472A1 (en) * 2011-03-22 2012-09-27 Mapi Pharma Ltd. Process and intermediates for the preparation of preladenant and related compounds
WO2012129381A1 (en) 2011-03-22 2012-09-27 Concert Pharmaceuticals Inc. Deuterated preladenant
WO2013024474A1 (en) * 2011-08-18 2013-02-21 Mapi Phrarma Ltd. Polymorphs of preladenant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264901B1 (it) * 1993-06-29 1996-10-17 Schering Plough S P A Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina
TWI288137B (en) * 2000-05-26 2007-10-11 Schering Corp Adenosine A2a receptor antagonists

Also Published As

Publication number Publication date
ES2293380T3 (es) 2008-03-16
US7235659B2 (en) 2007-06-26
WO2005054245A2 (en) 2005-06-16
DE602004009962T2 (de) 2008-08-28
ATE377599T1 (de) 2007-11-15
EP1689749B1 (de) 2007-11-07
US20090131663A1 (en) 2009-05-21
CA2547248A1 (en) 2005-06-16
US20060149060A1 (en) 2006-07-06
US7507822B2 (en) 2009-03-24
EP1689749A2 (de) 2006-08-16
US20070238874A1 (en) 2007-10-11
JP2007513091A (ja) 2007-05-24
WO2005054245A3 (en) 2005-08-11

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