DE60105314D1 - Verfahren zur herstellung von taxanderivaten - Google Patents

Verfahren zur herstellung von taxanderivaten

Info

Publication number
DE60105314D1
DE60105314D1 DE60105314T DE60105314T DE60105314D1 DE 60105314 D1 DE60105314 D1 DE 60105314D1 DE 60105314 T DE60105314 T DE 60105314T DE 60105314 T DE60105314 T DE 60105314T DE 60105314 D1 DE60105314 D1 DE 60105314D1
Authority
DE
Germany
Prior art keywords
producing
taxan derivatives
derivatives
producing taxan
isobutylisoserinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60105314T
Other languages
English (en)
Other versions
DE60105314T2 (de
Inventor
Alessandro Pontiroli
Ezio Bombardelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indena SpA
Original Assignee
Indena SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena SpA filed Critical Indena SpA
Publication of DE60105314D1 publication Critical patent/DE60105314D1/de
Application granted granted Critical
Publication of DE60105314T2 publication Critical patent/DE60105314T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE60105314T 2000-11-28 2001-11-22 Verfahren zur herstellung von taxanderivaten Expired - Lifetime DE60105314T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI20002553 2000-11-28
IT2000MI002553A IT1320107B1 (it) 2000-11-28 2000-11-28 Procedimento per la preparazione di derivati tassanici.
PCT/EP2001/013614 WO2002044161A2 (en) 2000-11-28 2001-11-22 A process for the preparation of taxan derivatives

Publications (2)

Publication Number Publication Date
DE60105314D1 true DE60105314D1 (de) 2004-10-07
DE60105314T2 DE60105314T2 (de) 2005-09-29

Family

ID=11446144

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105314T Expired - Lifetime DE60105314T2 (de) 2000-11-28 2001-11-22 Verfahren zur herstellung von taxanderivaten

Country Status (24)

Country Link
US (1) US6737534B2 (de)
EP (1) EP1347984B1 (de)
JP (1) JP4237490B2 (de)
KR (1) KR100799393B1 (de)
CN (1) CN1243005C (de)
AT (1) ATE275149T1 (de)
AU (2) AU2002229563B2 (de)
CA (1) CA2430070C (de)
CZ (1) CZ300793B6 (de)
DE (1) DE60105314T2 (de)
DK (1) DK1347984T3 (de)
ES (1) ES2227316T3 (de)
HK (1) HK1059778A1 (de)
HU (1) HUP0302765A3 (de)
IL (2) IL156141A0 (de)
IT (1) IT1320107B1 (de)
NO (1) NO328143B1 (de)
PL (1) PL362392A1 (de)
PT (1) PT1347984E (de)
RU (1) RU2275365C2 (de)
SI (1) SI1347984T1 (de)
SK (1) SK286711B6 (de)
TR (1) TR200402546T4 (de)
WO (1) WO2002044161A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
EP1712552A1 (de) * 2005-04-11 2006-10-18 INDENA S.p.A. Teilsynthese für die Herstellung von 10-deacetyl-n-debenzoyl-paclitaxel
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US7232916B1 (en) 2006-05-11 2007-06-19 Indena S.P.A. Process for the preparation of a taxane derivative
ES2389518T3 (es) 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
EP2080763A1 (de) 2008-01-18 2009-07-22 INDENA S.p.A. Ortataxel in Kristallform I
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1275435B (it) * 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.

Also Published As

Publication number Publication date
EP1347984B1 (de) 2004-09-01
HUP0302765A2 (hu) 2003-11-28
SK286711B6 (sk) 2009-03-05
KR20030051864A (ko) 2003-06-25
NO328143B1 (no) 2009-12-14
NO20032401L (no) 2003-05-27
US20040030164A1 (en) 2004-02-12
ITMI20002553A1 (it) 2002-05-28
AU2002229563B2 (en) 2006-03-30
DK1347984T3 (da) 2005-01-10
ATE275149T1 (de) 2004-09-15
KR100799393B1 (ko) 2008-01-30
CN1243005C (zh) 2006-02-22
RU2275365C2 (ru) 2006-04-27
WO2002044161A3 (en) 2002-07-25
IL156141A0 (en) 2003-12-23
TR200402546T4 (tr) 2004-12-21
ES2227316T3 (es) 2005-04-01
CA2430070C (en) 2011-09-13
IL156141A (en) 2007-02-11
CN1478091A (zh) 2004-02-25
PT1347984E (pt) 2004-11-30
PL362392A1 (en) 2004-11-02
IT1320107B1 (it) 2003-11-18
HK1059778A1 (en) 2004-07-16
US6737534B2 (en) 2004-05-18
JP2004519434A (ja) 2004-07-02
HUP0302765A3 (en) 2005-02-28
CA2430070A1 (en) 2002-06-06
JP4237490B2 (ja) 2009-03-11
WO2002044161A2 (en) 2002-06-06
AU2956302A (en) 2002-06-11
CZ300793B6 (cs) 2009-08-12
EP1347984A2 (de) 2003-10-01
SK6422003A3 (en) 2003-11-04
CZ20031474A3 (cs) 2003-08-13
NO20032401D0 (no) 2003-05-27
DE60105314T2 (de) 2005-09-29
SI1347984T1 (en) 2005-02-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC