ATE287399T1 - Verfahren zur herstellung eines pgd2-antagonisten - Google Patents
Verfahren zur herstellung eines pgd2-antagonistenInfo
- Publication number
- ATE287399T1 ATE287399T1 AT01981892T AT01981892T ATE287399T1 AT E287399 T1 ATE287399 T1 AT E287399T1 AT 01981892 T AT01981892 T AT 01981892T AT 01981892 T AT01981892 T AT 01981892T AT E287399 T1 ATE287399 T1 AT E287399T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- pgd2 antagonist
- pgd2
- antagonist
- benzothiophenecarboxamide
- Prior art date
Links
- 102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 title abstract 2
- 101000988802 Homo sapiens Hematopoietic prostaglandin D synthase Proteins 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- BHMBVRSPMRCCGG-OUTUXVNYSA-N prostaglandin D2 Chemical compound CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O BHMBVRSPMRCCGG-OUTUXVNYSA-N 0.000 title abstract 2
- BHMBVRSPMRCCGG-UHFFFAOYSA-N prostaglandine D2 Natural products CCCCCC(O)C=CC1C(CC=CCCCC(O)=O)C(O)CC1=O BHMBVRSPMRCCGG-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- GYSCBCSGKXNZRH-UHFFFAOYSA-N 1-benzothiophene-2-carboxamide Chemical compound C1=CC=C2SC(C(=O)N)=CC2=C1 GYSCBCSGKXNZRH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24102700P | 2000-10-17 | 2000-10-17 | |
| PCT/US2001/042763 WO2002032892A1 (en) | 2000-10-17 | 2001-10-16 | Process for the preparation of pgd2 antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE287399T1 true ATE287399T1 (de) | 2005-02-15 |
Family
ID=22908942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01981892T ATE287399T1 (de) | 2000-10-17 | 2001-10-16 | Verfahren zur herstellung eines pgd2-antagonisten |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6693203B2 (de) |
| EP (1) | EP1334095B1 (de) |
| JP (1) | JP4017978B2 (de) |
| AT (1) | ATE287399T1 (de) |
| AU (1) | AU2002213505A1 (de) |
| DE (1) | DE60108515T2 (de) |
| WO (1) | WO2002032892A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005095397A1 (en) | 2004-03-11 | 2005-10-13 | Actelion Pharmaceuticals Ltd | Tetrahydropyridoindole derivatives |
| CN111925285A (zh) * | 2019-05-13 | 2020-11-13 | 上海北卡医药技术有限公司 | 一种7-苯基-6-庚炔酸的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0837052T3 (da) * | 1995-06-21 | 2007-01-02 | Shionogi & Co | Bicykliske aminoderivater og PGD2-antagonist indeholdende disse |
| DE19534868A1 (de) | 1995-09-20 | 1997-03-27 | Bayer Ag | Benzothiophen-2-carboxamid-S,S-dioxide für den Antifouling-Einsatz |
| EP0944614B1 (de) | 1996-12-13 | 2002-09-11 | Shionogi & Co., Ltd. | Benzothiophenecarboxamid-derivate und diese enthaltende pgd2 antagonisten |
-
2001
- 2001-10-16 EP EP01981892A patent/EP1334095B1/de not_active Expired - Lifetime
- 2001-10-16 US US10/398,741 patent/US6693203B2/en not_active Expired - Fee Related
- 2001-10-16 WO PCT/US2001/042763 patent/WO2002032892A1/en not_active Ceased
- 2001-10-16 AU AU2002213505A patent/AU2002213505A1/en not_active Abandoned
- 2001-10-16 AT AT01981892T patent/ATE287399T1/de not_active IP Right Cessation
- 2001-10-16 DE DE60108515T patent/DE60108515T2/de not_active Expired - Fee Related
- 2001-10-16 JP JP2002536274A patent/JP4017978B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60108515D1 (de) | 2005-02-24 |
| US20030199702A1 (en) | 2003-10-23 |
| DE60108515T2 (de) | 2006-01-12 |
| JP4017978B2 (ja) | 2007-12-05 |
| AU2002213505A1 (en) | 2002-04-29 |
| EP1334095B1 (de) | 2005-01-19 |
| EP1334095A4 (de) | 2004-03-17 |
| JP2004513894A (ja) | 2004-05-13 |
| WO2002032892A1 (en) | 2002-04-25 |
| EP1334095A1 (de) | 2003-08-13 |
| US6693203B2 (en) | 2004-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |