DK0923555T3 - pyrrolidin, piperidin og hexahydroazepin til behandling af trombotiske lidelser - Google Patents
pyrrolidin, piperidin og hexahydroazepin til behandling af trombotiske lidelserInfo
- Publication number
- DK0923555T3 DK0923555T3 DK97922518T DK97922518T DK0923555T3 DK 0923555 T3 DK0923555 T3 DK 0923555T3 DK 97922518 T DK97922518 T DK 97922518T DK 97922518 T DK97922518 T DK 97922518T DK 0923555 T3 DK0923555 T3 DK 0923555T3
- Authority
- DK
- Denmark
- Prior art keywords
- hexahydroazepine
- pyrrolidine
- piperidine
- treatment
- thrombotic disorders
- Prior art date
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 3
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
- 208000007536 Thrombosis Diseases 0.000 title 1
- ZSIQJIWKELUFRJ-UHFFFAOYSA-N azepane Chemical compound C1CCCNCC1 ZSIQJIWKELUFRJ-UHFFFAOYSA-N 0.000 title 1
- 108010073038 Penicillin Amidase Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1667596P | 1996-05-01 | 1996-05-01 | |
| PCT/US1997/007130 WO1997041102A1 (en) | 1996-05-01 | 1997-04-29 | Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0923555T3 true DK0923555T3 (da) | 2005-08-15 |
Family
ID=21778348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97922518T DK0923555T3 (da) | 1996-05-01 | 1997-04-29 | pyrrolidin, piperidin og hexahydroazepin til behandling af trombotiske lidelser |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6069254A (da) |
| EP (2) | EP1988078B1 (da) |
| JP (1) | JP4328387B2 (da) |
| KR (1) | KR100510854B1 (da) |
| CN (1) | CN1286684A (da) |
| AT (2) | ATE421952T1 (da) |
| AU (1) | AU726594B2 (da) |
| BG (1) | BG64276B1 (da) |
| BR (1) | BR9710434A (da) |
| CA (1) | CA2258701C (da) |
| CZ (2) | CZ293912B6 (da) |
| DE (2) | DE69733565T2 (da) |
| DK (1) | DK0923555T3 (da) |
| EE (1) | EE03823B1 (da) |
| ES (3) | ES2396725T3 (da) |
| GE (1) | GEP20002187B (da) |
| HK (1) | HK1041406A1 (da) |
| NZ (1) | NZ332585A (da) |
| PL (1) | PL190796B1 (da) |
| PT (1) | PT923555E (da) |
| RU (1) | RU2194038C2 (da) |
| SK (1) | SK149798A3 (da) |
| TR (1) | TR199802207T2 (da) |
| UA (1) | UA70285C2 (da) |
| WO (1) | WO1997041102A1 (da) |
| YU (1) | YU48698A (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6066651A (en) * | 1997-10-29 | 2000-05-23 | Ortho-Mcneil Pharmaceutical, Inc. | Orally-active nipecotamide glycolamide esters for the treatment of thrombosis disorders |
| US6020347A (en) * | 1997-11-18 | 2000-02-01 | Merck & Co., Inc. | 4-substituted-4-piperidine carboxamide derivatives |
| PT1165543E (pt) * | 1999-03-22 | 2003-10-31 | Ortho Mcneil Pharm Inc | Processo para a preparacao de acido ¬s-(r*,s*)|-beta-¬¬¬1-¬1-oxo-3-(4-piperidinil)propil|-3-piperidinil|-carbonil|amino|-3-piridinopropanoico e derivados |
| BR0009856A (pt) * | 1999-03-22 | 2002-02-05 | Ortho Mcneil Pharm Inc | Sìntese de 3-amino-3-aril propanoatos |
| HUP0201347A3 (en) | 1999-03-22 | 2002-12-28 | Ortho Mcneil Pharm Inc | Process of preparing 3s-3-amino-3-aryl propionic acid and derivatives thereof |
| CA2352957A1 (en) * | 1999-09-29 | 2001-04-05 | Ortho-Mcneil Pharmaceutical, Inc. | Isonipecotamides for the treatment of integrin-mediated disorders |
| AUPQ570100A0 (en) * | 2000-02-17 | 2000-03-09 | Fujisawa Pharmaceutical Co., Ltd. | Beta-alanine derivatives and their use as receptor antagonists |
| SE0001803D0 (sv) * | 2000-05-16 | 2000-05-16 | Astrazeneca Ab | New compounds i |
| US7081460B2 (en) | 2001-04-09 | 2006-07-25 | Ortho-Mcneil Pharmaceutical, Inc. | Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders |
| CA2492035A1 (en) | 2002-07-11 | 2004-01-15 | Vicuron Pharmaceuticals, Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| DE10355461A1 (de) * | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| WO2005079863A1 (ja) | 2004-02-25 | 2005-09-01 | Astellas Pharma Inc. | 血栓造影剤 |
| BRPI0509150B8 (pt) * | 2004-03-24 | 2021-05-25 | Jerini Ag | compostos para a inibição de angiogênese e uso destes |
| US7687665B2 (en) | 2004-06-24 | 2010-03-30 | Incyte Corporation | 2-methylprop anamides and their use as pharmaceuticals |
| US8071624B2 (en) | 2004-06-24 | 2011-12-06 | Incyte Corporation | N-substituted piperidines and their use as pharmaceuticals |
| WO2008106202A1 (en) * | 2007-02-27 | 2008-09-04 | Housey Gerard M | Theramutein modulators |
| US8207298B2 (en) | 2008-05-01 | 2012-06-26 | Archemix Corp. | Methods of separating biopolymer conjugated molecules from unconjugated molecules |
| MX2012005759A (es) * | 2009-11-18 | 2012-10-03 | Fab Pharma S A S | Acrilamidas heterociclicas novedosas y su uso como farmacos. |
| ES2621379T3 (es) * | 2011-08-17 | 2017-07-03 | Piramal Imaging Sa | Compuestos para la unión a la glicoproteína IIb/IIIa específica de las plaquetas y su utilización para la formación de imágenes de trombos |
| JP2016508507A (ja) | 2013-02-12 | 2016-03-22 | バイエル・ファルマ・アクティエンゲゼルシャフト | 血小板特異的糖タンパク質ＩＩｂ／ＩＩＩａに結合するための金属キレート化合物 |
| PT3265443T (pt) * | 2015-07-08 | 2020-02-14 | Korea Res Inst Chemical Tech | Derivados de pirrolidina carboxamido e métodos de preparação e utilização dos mesmos |
| EP3759070A4 (en) | 2018-02-28 | 2021-12-08 | Bridge Biotherapeutics, Inc. | WATER-SOLUBLE SALT OF LIPIDATED PEPTIDES AND PROCESS FOR THEIR PRODUCTION AND USE |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3435156A1 (de) * | 1984-09-25 | 1986-04-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung der stereoisomeren von 1-amino-alkylphosphonsaeuren oder 1-aminoalkylphosphinsaeuren |
| DK0669912T3 (da) * | 1993-09-22 | 2002-03-04 | Fujisawa Pharmaceutical Co | N-(3-Piperidinylcarbonyl)-beta-alaninderivater som PAF-antagonister |
| DE69426602T2 (de) * | 1993-10-19 | 2001-08-30 | Sumitomo Pharma | 2,3-diaminopropionsäurederivate |
| US5770575A (en) * | 1994-03-16 | 1998-06-23 | Ortho Pharmaceutical Corporation | Nipecotic acid derivatives as antithrombotic compounds |
| US5639765A (en) * | 1995-01-17 | 1997-06-17 | G. D. Searle & Co. | Guanidinoalkyl glycine β-amino acids useful for inhibiting bone loss |
| KR19980703107A (ko) * | 1995-03-17 | 1998-10-15 | 후지야마 아키라 | N-아실피페리디닐카보닐아미노카복실산 및 당단백질 IIB/IIa 길항제와 피브리노겐-혈소판 결합 억제제로서의 이의 용도 |
-
1997
- 1997-04-29 JP JP53913497A patent/JP4328387B2/ja not_active Expired - Lifetime
- 1997-04-29 AT AT01203872T patent/ATE421952T1/de not_active IP Right Cessation
- 1997-04-29 TR TR1998/02207T patent/TR199802207T2/xx unknown
- 1997-04-29 CA CA002258701A patent/CA2258701C/en not_active Expired - Lifetime
- 1997-04-29 EE EE9800371A patent/EE03823B1/xx not_active IP Right Cessation
- 1997-04-29 DK DK97922518T patent/DK0923555T3/da active
- 1997-04-29 WO PCT/US1997/007130 patent/WO1997041102A1/en active IP Right Grant
- 1997-04-29 EP EP08075675A patent/EP1988078B1/en not_active Expired - Lifetime
- 1997-04-29 US US08/841,016 patent/US6069254A/en not_active Expired - Lifetime
- 1997-04-29 BR BR9710434A patent/BR9710434A/pt not_active Application Discontinuation
- 1997-04-29 CZ CZ19983488A patent/CZ293912B6/cs not_active IP Right Cessation
- 1997-04-29 AU AU28166/97A patent/AU726594B2/en not_active Ceased
- 1997-04-29 RU RU98121706/04A patent/RU2194038C2/ru not_active IP Right Cessation
- 1997-04-29 NZ NZ332585A patent/NZ332585A/xx unknown
- 1997-04-29 SK SK1497-98A patent/SK149798A3/sk unknown
- 1997-04-29 CN CN97194303A patent/CN1286684A/zh active Pending
- 1997-04-29 ES ES08075675T patent/ES2396725T3/es not_active Expired - Lifetime
- 1997-04-29 AT AT97922518T patent/ATE297894T1/de not_active IP Right Cessation
- 1997-04-29 PL PL329695A patent/PL190796B1/pl unknown
- 1997-04-29 ES ES97922518T patent/ES2243996T3/es not_active Expired - Lifetime
- 1997-04-29 EP EP97922518A patent/EP0923555B1/en not_active Expired - Lifetime
- 1997-04-29 GE GEAP19974552A patent/GEP20002187B/en unknown
- 1997-04-29 PT PT97922518T patent/PT923555E/pt unknown
- 1997-04-29 ES ES01203872T patent/ES2320316T3/es not_active Expired - Lifetime
- 1997-04-29 KR KR1019980708783A patent/KR100510854B1/ko not_active IP Right Cessation
- 1997-04-29 DE DE69733565T patent/DE69733565T2/de not_active Expired - Lifetime
- 1997-04-29 DE DE69739239T patent/DE69739239D1/de not_active Expired - Lifetime
- 1997-04-29 UA UA98115886A patent/UA70285C2/uk unknown
- 1997-04-29 CZ CZ20021311A patent/CZ294094B6/cs not_active IP Right Cessation
-
1998
- 1998-10-30 YU YU48698A patent/YU48698A/sh unknown
- 1998-11-30 BG BG102966A patent/BG64276B1/bg unknown
-
2002
- 2002-04-23 HK HK02103047.5A patent/HK1041406A1/zh unknown
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