DK0918535T3 - Sammensætning med langvarig frigivelse af lægemidler indkapslet i mikropartikler af hyaluronsyre - Google Patents
Sammensætning med langvarig frigivelse af lægemidler indkapslet i mikropartikler af hyaluronsyreInfo
- Publication number
- DK0918535T3 DK0918535T3 DK98911246T DK98911246T DK0918535T3 DK 0918535 T3 DK0918535 T3 DK 0918535T3 DK 98911246 T DK98911246 T DK 98911246T DK 98911246 T DK98911246 T DK 98911246T DK 0918535 T3 DK0918535 T3 DK 0918535T3
- Authority
- DK
- Denmark
- Prior art keywords
- long
- hyaluronic acid
- drug composition
- release drug
- acid microparticles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019970012046A KR100236771B1 (ko) | 1997-04-01 | 1997-04-01 | 히아루론산을 이용한 약물의 서방성 미세입자 제형 |
EP98911246A EP0918535B1 (en) | 1997-04-01 | 1998-03-26 | Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid |
PCT/KR1998/000062 WO1998043664A1 (en) | 1997-04-01 | 1998-03-26 | Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0918535T3 true DK0918535T3 (da) | 2005-04-18 |
Family
ID=19501732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98911246T DK0918535T3 (da) | 1997-04-01 | 1998-03-26 | Sammensætning med langvarig frigivelse af lægemidler indkapslet i mikropartikler af hyaluronsyre |
Country Status (26)
Country | Link |
---|---|
US (3) | US20080063727A1 (zh) |
EP (1) | EP0918535B1 (zh) |
JP (1) | JP3445283B2 (zh) |
KR (1) | KR100236771B1 (zh) |
CN (1) | CN1132625C (zh) |
AR (1) | AR011208A1 (zh) |
AT (1) | ATE285245T1 (zh) |
AU (1) | AU721929B2 (zh) |
BG (1) | BG64642B1 (zh) |
BR (1) | BR9804802B1 (zh) |
CA (1) | CA2256596C (zh) |
DE (1) | DE69828252T2 (zh) |
DK (1) | DK0918535T3 (zh) |
ES (1) | ES2232939T3 (zh) |
HK (1) | HK1020885A1 (zh) |
HU (1) | HUP0000737A3 (zh) |
ID (1) | ID20584A (zh) |
IL (1) | IL127220A (zh) |
MY (1) | MY132812A (zh) |
NZ (1) | NZ333019A (zh) |
PL (1) | PL195223B1 (zh) |
PT (1) | PT918535E (zh) |
TR (1) | TR199802500T1 (zh) |
TW (1) | TW514532B (zh) |
WO (1) | WO1998043664A1 (zh) |
ZA (1) | ZA982533B (zh) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6221854B1 (en) * | 1996-03-05 | 2001-04-24 | Orquest, Inc. | Method of promoting bone growth with hyaluronic acid and growth factors |
KR100236771B1 (ko) * | 1997-04-01 | 2000-02-01 | 성재갑 | 히아루론산을 이용한 약물의 서방성 미세입자 제형 |
JP4234803B2 (ja) * | 1997-10-27 | 2009-03-04 | 久光製薬株式会社 | 薬物放出速度が制御された医薬組成物 |
US6623732B1 (en) | 1998-05-20 | 2003-09-23 | Highchem Company, Ltd. | Pharmaceutical formulation for nasal administration |
EP1091730A1 (de) * | 1998-06-29 | 2001-04-18 | White Spot AG | Verwendung von wachstumsfaktoren zur arzneimittelherstellung |
DK1140198T3 (da) | 1999-01-13 | 2008-03-10 | Alchemia Oncology Pty Ltd | Anvendelse af hyaluronan til fremstilling af et lægemiddel til forögelse af cytotoksiske lægemidlers virkningsgrad |
CA2324403C (en) | 1999-01-18 | 2005-12-13 | Lg Chemical Limited | Lipophilic microparticles containing a protein drug or antigen and formulation comprising same |
SE9904121D0 (sv) | 1999-11-15 | 1999-11-15 | Gustaf Jederstroem | Hydrophobe biomolecular structure |
US7785625B2 (en) | 2000-01-14 | 2010-08-31 | Lg Life Sciences, Limited | Lipophilic-coated microparticle containing a protein drug and formulation comprising same |
AU4724401A (en) | 2000-02-28 | 2001-09-12 | Genesegues Inc | Nanocapsule encapsulation system and method |
GB0004827D0 (en) * | 2000-02-29 | 2000-04-19 | Quadrant Holdings Cambridge | Compositions |
AUPQ879500A0 (en) * | 2000-07-14 | 2000-08-10 | Meditech Research Limited | Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease |
US9066919B2 (en) * | 2000-07-14 | 2015-06-30 | Alchemia Oncology Pty Limited | Hyaluronan as a chemo-sensitizer in the treatment of cancer |
JP4931282B2 (ja) * | 2000-10-02 | 2012-05-16 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
WO2002053136A1 (fr) | 2000-12-28 | 2002-07-11 | Takeda Chemical Industries, Ltd. | Preparations a liberation soutenue |
WO2002085399A1 (en) * | 2001-04-20 | 2002-10-31 | Takeda Chemical Industries, Ltd. | Peptide-containing preparations |
US20050042303A1 (en) * | 2001-08-27 | 2005-02-24 | Brown Tracey Jean | Therapeutic protocols |
GB0129489D0 (en) * | 2001-12-10 | 2002-01-30 | Quadrant Healthcare Uk Ltd | Sustained-release compositions |
JP4745826B2 (ja) * | 2003-11-14 | 2011-08-10 | 中外製薬株式会社 | 架橋多糖微粒子およびその製造方法 |
WO2005116130A1 (en) * | 2004-05-27 | 2005-12-08 | Novozymes Biopolymer A/S | A fast dissolving dried hyaluronic acid product |
EP1790665B1 (en) | 2004-09-07 | 2014-11-05 | Chugai Seiyaku Kabushiki Kaisha | Process for producing water-soluble modified hyaluronic acid |
TW200640492A (en) * | 2005-02-21 | 2006-12-01 | Lg Life Sciences Ltd | Sustained release composition of protein drug |
US8017152B2 (en) | 2005-05-27 | 2011-09-13 | Stratosphere Pharma Ab | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
EP1912658B1 (en) * | 2005-07-27 | 2017-01-25 | Alchemia Oncology Pty Limited | Therapeutic protocols using hyaluronan |
US8319625B2 (en) * | 2005-09-01 | 2012-11-27 | Simplexgrinnell Lp | Fire alarm textual notification related application |
JP5627181B2 (ja) * | 2005-09-07 | 2014-11-19 | アルケミア オンコロジー ピーティーワイ リミテッド | ヒアルロナンおよび治療用抗体を含む治療用組成物ならびに治療方法 |
EP1976551A4 (en) | 2005-12-23 | 2009-12-30 | Altus Pharmaceuticals Inc | COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF |
KR100939983B1 (ko) | 2006-10-31 | 2010-02-03 | 주식회사 엘지생명과학 | 히아루론산-소수성 폴리 아미노산 공중합체 |
FR2931360B1 (fr) * | 2008-05-20 | 2012-05-18 | Centre Nat Rech Scient | Nanoparticules contenant un peptide, vecteurs les contenant et utilisations pharmaceutiques desdits nanoparticules et vecteurs |
US9012606B2 (en) | 2009-04-22 | 2015-04-21 | Alteogen, Inc. | In vivo half life increased fusion protein or peptide maintained by sustained in vivo release, and method for increasng in vivo half-life using same |
HUE038405T2 (hu) | 2009-12-15 | 2018-10-29 | Ascendis Pharma Endocrinology Div A/S | Átmenetileg polimer hordozóhoz kapcsolt száraz növekedési hormon készítmény |
WO2012172433A2 (en) | 2011-06-14 | 2012-12-20 | Ipsen Pharma S.A.S. | A sustained-release composition containing peptides as active ingredient |
US9399019B2 (en) | 2012-05-09 | 2016-07-26 | Evonik Corporation | Polymorph compositions, methods of making, and uses thereof |
EP2857417B1 (en) | 2012-06-05 | 2018-02-14 | CJ Healthcare Corporation | Highly glycosylated long-acting human growth hormone protein and production method for same |
WO2015018461A1 (fr) | 2013-08-09 | 2015-02-12 | Genbiotech | Compositions therapeutiques comprenant d'acide hyaluronique |
EP3188716B1 (en) | 2014-09-03 | 2022-10-26 | GeneSegues, Inc. | Therapeutic nanoparticles and related compositions, methods and systems |
EP3988083A1 (en) | 2014-11-21 | 2022-04-27 | Ascendis Pharma Endocrinology Division A/S | Long-acting growth hormone dosage forms |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4971782A (en) * | 1983-09-14 | 1990-11-20 | Peroxydent Group | Periodontal composition and method |
US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
JPH0725689B2 (ja) * | 1986-10-07 | 1995-03-22 | 中外製薬株式会社 | 顆粒球コロニ−刺激因子を含有する徐放性製剤 |
JPH02213A (ja) * | 1987-10-19 | 1990-01-05 | Taiho Yakuhin Kogyo Kk | 生理活性ペプチド持続製剤 |
JPH01287041A (ja) * | 1988-05-13 | 1989-11-17 | Rooman Kogyo:Kk | 徐放性製剤 |
JPH03215430A (ja) * | 1990-01-19 | 1991-09-20 | Kita Kiyoshi | 関節腔抗凝固剤 |
US5707644A (en) * | 1989-11-04 | 1998-01-13 | Danbiosyst Uk Limited | Small particle compositions for intranasal drug delivery |
IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
JPH04282322A (ja) * | 1991-03-08 | 1992-10-07 | Denki Kagaku Kogyo Kk | 生物活性ペプチド製剤 |
JP3283288B2 (ja) * | 1991-03-08 | 2002-05-20 | 電気化学工業株式会社 | 生理活性ペプチド製剤 |
JPH0565231A (ja) * | 1991-03-12 | 1993-03-19 | Takeda Chem Ind Ltd | エリスロポエチンの持続性製剤 |
IT1247472B (it) * | 1991-05-31 | 1994-12-17 | Fidia Spa | Processo per la preparazione di microsfere contenenti componenti biologicamente attivi. |
JP3449738B2 (ja) * | 1991-07-10 | 2003-09-22 | 武田薬品工業株式会社 | 水溶性組成物 |
JPH05186364A (ja) * | 1991-08-01 | 1993-07-27 | Takeda Chem Ind Ltd | 水溶性組成物 |
ATE154241T1 (de) * | 1991-10-01 | 1997-06-15 | Takeda Chemical Industries Ltd | Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe |
JPH08198772A (ja) * | 1994-11-25 | 1996-08-06 | Kirin Brewery Co Ltd | 顆粒球コロニー刺激因子含有粉末経鼻投与製剤 |
KR100201352B1 (ko) * | 1995-03-16 | 1999-06-15 | 성재갑 | 단일주사 백신 제형 |
US5641749A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
US7276251B2 (en) * | 1997-04-01 | 2007-10-02 | Lg Life Sciences, Ltd., Inc. | Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid |
KR100236771B1 (ko) * | 1997-04-01 | 2000-02-01 | 성재갑 | 히아루론산을 이용한 약물의 서방성 미세입자 제형 |
JPH09309843A (ja) * | 1996-05-21 | 1997-12-02 | Shiseido Co Ltd | ヒアルロン酸含有経肺投与用製剤 |
US6113947A (en) * | 1997-06-13 | 2000-09-05 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
TW577758B (en) * | 1997-10-27 | 2004-03-01 | Ssp Co Ltd | Intra-articular preparation for the treatment of arthropathy |
JP4234803B2 (ja) * | 1997-10-27 | 2009-03-04 | 久光製薬株式会社 | 薬物放出速度が制御された医薬組成物 |
CA2324403C (en) * | 1999-01-18 | 2005-12-13 | Lg Chemical Limited | Lipophilic microparticles containing a protein drug or antigen and formulation comprising same |
-
1997
- 1997-04-01 KR KR1019970012046A patent/KR100236771B1/ko not_active IP Right Cessation
-
1998
- 1998-03-25 ZA ZA982533A patent/ZA982533B/xx unknown
- 1998-03-25 MY MYPI98001281A patent/MY132812A/en unknown
- 1998-03-26 IL IL12722098A patent/IL127220A/en not_active IP Right Cessation
- 1998-03-26 PL PL98330230A patent/PL195223B1/pl not_active IP Right Cessation
- 1998-03-26 AU AU65241/98A patent/AU721929B2/en not_active Expired
- 1998-03-26 ID IDW980121D patent/ID20584A/id unknown
- 1998-03-26 JP JP54148898A patent/JP3445283B2/ja not_active Expired - Lifetime
- 1998-03-26 DE DE69828252T patent/DE69828252T2/de not_active Revoked
- 1998-03-26 WO PCT/KR1998/000062 patent/WO1998043664A1/en active IP Right Grant
- 1998-03-26 ES ES98911246T patent/ES2232939T3/es not_active Expired - Lifetime
- 1998-03-26 HU HU0000737A patent/HUP0000737A3/hu unknown
- 1998-03-26 PT PT98911246T patent/PT918535E/pt unknown
- 1998-03-26 BR BRPI9804802-3A patent/BR9804802B1/pt not_active IP Right Cessation
- 1998-03-26 NZ NZ333019A patent/NZ333019A/xx not_active IP Right Cessation
- 1998-03-26 AT AT98911246T patent/ATE285245T1/de active
- 1998-03-26 EP EP98911246A patent/EP0918535B1/en not_active Revoked
- 1998-03-26 CN CN988004003A patent/CN1132625C/zh not_active Expired - Lifetime
- 1998-03-26 TR TR1998/02500T patent/TR199802500T1/xx unknown
- 1998-03-26 DK DK98911246T patent/DK0918535T3/da active
- 1998-03-26 CA CA002256596A patent/CA2256596C/en not_active Expired - Lifetime
- 1998-03-30 TW TW087104742A patent/TW514532B/zh not_active IP Right Cessation
- 1998-04-01 AR ARP980101469A patent/AR011208A1/es active IP Right Grant
- 1998-11-30 BG BG102969A patent/BG64642B1/bg unknown
-
1999
- 1999-12-30 HK HK99106197A patent/HK1020885A1/xx not_active IP Right Cessation
-
2007
- 2007-10-31 US US11/979,148 patent/US20080063727A1/en not_active Abandoned
-
2010
- 2010-09-29 US US12/893,203 patent/US20110020458A1/en not_active Abandoned
-
2013
- 2013-02-20 US US13/771,722 patent/US20130230598A1/en not_active Abandoned
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