PT918535E - Formulacao de libertacao controlada de farmacos encapsulados em microparticulas de acido hialuronico - Google Patents

Formulacao de libertacao controlada de farmacos encapsulados em microparticulas de acido hialuronico

Info

Publication number
PT918535E
PT918535E PT98911246T PT98911246T PT918535E PT 918535 E PT918535 E PT 918535E PT 98911246 T PT98911246 T PT 98911246T PT 98911246 T PT98911246 T PT 98911246T PT 918535 E PT918535 E PT 918535E
Authority
PT
Portugal
Prior art keywords
pharmacos
encapsulated
formulation
hyaluronic acid
acid microparticles
Prior art date
Application number
PT98911246T
Other languages
English (en)
Inventor
Kim Myung Jin
Kim Sun Jin
Kwon Oh Ryong
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19501732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT918535(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of PT918535E publication Critical patent/PT918535E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT98911246T 1997-04-01 1998-03-26 Formulacao de libertacao controlada de farmacos encapsulados em microparticulas de acido hialuronico PT918535E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970012046A KR100236771B1 (ko) 1997-04-01 1997-04-01 히아루론산을 이용한 약물의 서방성 미세입자 제형

Publications (1)

Publication Number Publication Date
PT918535E true PT918535E (pt) 2005-03-31

Family

ID=19501732

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98911246T PT918535E (pt) 1997-04-01 1998-03-26 Formulacao de libertacao controlada de farmacos encapsulados em microparticulas de acido hialuronico

Country Status (26)

Country Link
US (3) US20080063727A1 (pt)
EP (1) EP0918535B1 (pt)
JP (1) JP3445283B2 (pt)
KR (1) KR100236771B1 (pt)
CN (1) CN1132625C (pt)
AR (1) AR011208A1 (pt)
AT (1) ATE285245T1 (pt)
AU (1) AU721929B2 (pt)
BG (1) BG64642B1 (pt)
BR (1) BR9804802B1 (pt)
CA (1) CA2256596C (pt)
DE (1) DE69828252T2 (pt)
DK (1) DK0918535T3 (pt)
ES (1) ES2232939T3 (pt)
HK (1) HK1020885A1 (pt)
HU (1) HUP0000737A3 (pt)
ID (1) ID20584A (pt)
IL (1) IL127220A (pt)
MY (1) MY132812A (pt)
NZ (1) NZ333019A (pt)
PL (1) PL195223B1 (pt)
PT (1) PT918535E (pt)
TR (1) TR199802500T1 (pt)
TW (1) TW514532B (pt)
WO (1) WO1998043664A1 (pt)
ZA (1) ZA982533B (pt)

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JP4234803B2 (ja) * 1997-10-27 2009-03-04 久光製薬株式会社 薬物放出速度が制御された医薬組成物
US6623732B1 (en) 1998-05-20 2003-09-23 Highchem Company, Ltd. Pharmaceutical formulation for nasal administration
EP1091730A1 (de) * 1998-06-29 2001-04-18 White Spot AG Verwendung von wachstumsfaktoren zur arzneimittelherstellung
DK1140198T3 (da) 1999-01-13 2008-03-10 Alchemia Oncology Pty Ltd Anvendelse af hyaluronan til fremstilling af et lægemiddel til forögelse af cytotoksiske lægemidlers virkningsgrad
CA2324403C (en) 1999-01-18 2005-12-13 Lg Chemical Limited Lipophilic microparticles containing a protein drug or antigen and formulation comprising same
SE9904121D0 (sv) 1999-11-15 1999-11-15 Gustaf Jederstroem Hydrophobe biomolecular structure
US7785625B2 (en) 2000-01-14 2010-08-31 Lg Life Sciences, Limited Lipophilic-coated microparticle containing a protein drug and formulation comprising same
AU4724401A (en) 2000-02-28 2001-09-12 Genesegues Inc Nanocapsule encapsulation system and method
GB0004827D0 (en) * 2000-02-29 2000-04-19 Quadrant Holdings Cambridge Compositions
AUPQ879500A0 (en) * 2000-07-14 2000-08-10 Meditech Research Limited Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease
US9066919B2 (en) * 2000-07-14 2015-06-30 Alchemia Oncology Pty Limited Hyaluronan as a chemo-sensitizer in the treatment of cancer
JP4931282B2 (ja) * 2000-10-02 2012-05-16 日本ケミカルリサーチ株式会社 生理活性ペプチド含有粉末
WO2002053136A1 (fr) 2000-12-28 2002-07-11 Takeda Chemical Industries, Ltd. Preparations a liberation soutenue
WO2002085399A1 (en) * 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Peptide-containing preparations
US20050042303A1 (en) * 2001-08-27 2005-02-24 Brown Tracey Jean Therapeutic protocols
GB0129489D0 (en) * 2001-12-10 2002-01-30 Quadrant Healthcare Uk Ltd Sustained-release compositions
JP4745826B2 (ja) * 2003-11-14 2011-08-10 中外製薬株式会社 架橋多糖微粒子およびその製造方法
WO2005116130A1 (en) * 2004-05-27 2005-12-08 Novozymes Biopolymer A/S A fast dissolving dried hyaluronic acid product
EP1790665B1 (en) 2004-09-07 2014-11-05 Chugai Seiyaku Kabushiki Kaisha Process for producing water-soluble modified hyaluronic acid
TW200640492A (en) * 2005-02-21 2006-12-01 Lg Life Sciences Ltd Sustained release composition of protein drug
US8017152B2 (en) 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
EP1912658B1 (en) * 2005-07-27 2017-01-25 Alchemia Oncology Pty Limited Therapeutic protocols using hyaluronan
US8319625B2 (en) * 2005-09-01 2012-11-27 Simplexgrinnell Lp Fire alarm textual notification related application
JP5627181B2 (ja) * 2005-09-07 2014-11-19 アルケミア オンコロジー ピーティーワイ リミテッド ヒアルロナンおよび治療用抗体を含む治療用組成物ならびに治療方法
EP1976551A4 (en) 2005-12-23 2009-12-30 Altus Pharmaceuticals Inc COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF
KR100939983B1 (ko) 2006-10-31 2010-02-03 주식회사 엘지생명과학 히아루론산-소수성 폴리 아미노산 공중합체
FR2931360B1 (fr) * 2008-05-20 2012-05-18 Centre Nat Rech Scient Nanoparticules contenant un peptide, vecteurs les contenant et utilisations pharmaceutiques desdits nanoparticules et vecteurs
US9012606B2 (en) 2009-04-22 2015-04-21 Alteogen, Inc. In vivo half life increased fusion protein or peptide maintained by sustained in vivo release, and method for increasng in vivo half-life using same
HUE038405T2 (hu) 2009-12-15 2018-10-29 Ascendis Pharma Endocrinology Div A/S Átmenetileg polimer hordozóhoz kapcsolt száraz növekedési hormon készítmény
WO2012172433A2 (en) 2011-06-14 2012-12-20 Ipsen Pharma S.A.S. A sustained-release composition containing peptides as active ingredient
US9399019B2 (en) 2012-05-09 2016-07-26 Evonik Corporation Polymorph compositions, methods of making, and uses thereof
EP2857417B1 (en) 2012-06-05 2018-02-14 CJ Healthcare Corporation Highly glycosylated long-acting human growth hormone protein and production method for same
WO2015018461A1 (fr) 2013-08-09 2015-02-12 Genbiotech Compositions therapeutiques comprenant d'acide hyaluronique
EP3188716B1 (en) 2014-09-03 2022-10-26 GeneSegues, Inc. Therapeutic nanoparticles and related compositions, methods and systems
EP3988083A1 (en) 2014-11-21 2022-04-27 Ascendis Pharma Endocrinology Division A/S Long-acting growth hormone dosage forms

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US4971782A (en) * 1983-09-14 1990-11-20 Peroxydent Group Periodontal composition and method
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
JPH0725689B2 (ja) * 1986-10-07 1995-03-22 中外製薬株式会社 顆粒球コロニ−刺激因子を含有する徐放性製剤
JPH02213A (ja) * 1987-10-19 1990-01-05 Taiho Yakuhin Kogyo Kk 生理活性ペプチド持続製剤
JPH01287041A (ja) * 1988-05-13 1989-11-17 Rooman Kogyo:Kk 徐放性製剤
JPH03215430A (ja) * 1990-01-19 1991-09-20 Kita Kiyoshi 関節腔抗凝固剤
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
JPH04282322A (ja) * 1991-03-08 1992-10-07 Denki Kagaku Kogyo Kk 生物活性ペプチド製剤
JP3283288B2 (ja) * 1991-03-08 2002-05-20 電気化学工業株式会社 生理活性ペプチド製剤
JPH0565231A (ja) * 1991-03-12 1993-03-19 Takeda Chem Ind Ltd エリスロポエチンの持続性製剤
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
JP3449738B2 (ja) * 1991-07-10 2003-09-22 武田薬品工業株式会社 水溶性組成物
JPH05186364A (ja) * 1991-08-01 1993-07-27 Takeda Chem Ind Ltd 水溶性組成物
ATE154241T1 (de) * 1991-10-01 1997-06-15 Takeda Chemical Industries Ltd Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe
JPH08198772A (ja) * 1994-11-25 1996-08-06 Kirin Brewery Co Ltd 顆粒球コロニー刺激因子含有粉末経鼻投与製剤
KR100201352B1 (ko) * 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
US5641749A (en) * 1995-11-29 1997-06-24 Amgen Inc. Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product
US7276251B2 (en) * 1997-04-01 2007-10-02 Lg Life Sciences, Ltd., Inc. Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid
KR100236771B1 (ko) * 1997-04-01 2000-02-01 성재갑 히아루론산을 이용한 약물의 서방성 미세입자 제형
JPH09309843A (ja) * 1996-05-21 1997-12-02 Shiseido Co Ltd ヒアルロン酸含有経肺投与用製剤
US6113947A (en) * 1997-06-13 2000-09-05 Genentech, Inc. Controlled release microencapsulated NGF formulation
TW577758B (en) * 1997-10-27 2004-03-01 Ssp Co Ltd Intra-articular preparation for the treatment of arthropathy
JP4234803B2 (ja) * 1997-10-27 2009-03-04 久光製薬株式会社 薬物放出速度が制御された医薬組成物
CA2324403C (en) * 1999-01-18 2005-12-13 Lg Chemical Limited Lipophilic microparticles containing a protein drug or antigen and formulation comprising same

Also Published As

Publication number Publication date
KR100236771B1 (ko) 2000-02-01
TR199802500T1 (xx) 1999-06-21
ATE285245T1 (de) 2005-01-15
HUP0000737A2 (hu) 2000-09-28
PL330230A1 (en) 1999-05-10
BR9804802A (pt) 1999-08-17
US20130230598A1 (en) 2013-09-05
JP3445283B2 (ja) 2003-09-08
CA2256596A1 (en) 1998-10-08
AU6524198A (en) 1998-10-22
AR011208A1 (es) 2000-08-02
BG102969A (en) 1999-09-30
BG64642B1 (bg) 2005-10-31
NZ333019A (en) 1999-08-30
ZA982533B (en) 1998-09-30
JPH11513047A (ja) 1999-11-09
BR9804802B1 (pt) 2011-04-19
HUP0000737A3 (en) 2003-05-28
MY132812A (en) 2007-10-31
DE69828252D1 (de) 2005-01-27
DK0918535T3 (da) 2005-04-18
US20110020458A1 (en) 2011-01-27
ID20584A (id) 1999-01-21
ES2232939T3 (es) 2005-06-01
IL127220A0 (en) 1999-09-22
KR19980075759A (ko) 1998-11-16
AU721929B2 (en) 2000-07-20
CN1222857A (zh) 1999-07-14
CA2256596C (en) 2005-12-13
DE69828252T2 (de) 2005-11-10
EP0918535B1 (en) 2004-12-22
IL127220A (en) 2004-12-15
US20080063727A1 (en) 2008-03-13
HK1020885A1 (en) 2000-05-26
WO1998043664A1 (en) 1998-10-08
CN1132625C (zh) 2003-12-31
PL195223B1 (pl) 2007-08-31
TW514532B (en) 2002-12-21
EP0918535A1 (en) 1999-06-02

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