NO20005913L - Legemiddelsammensetning - Google Patents
LegemiddelsammensetningInfo
- Publication number
- NO20005913L NO20005913L NO20005913A NO20005913A NO20005913L NO 20005913 L NO20005913 L NO 20005913L NO 20005913 A NO20005913 A NO 20005913A NO 20005913 A NO20005913 A NO 20005913A NO 20005913 L NO20005913 L NO 20005913L
- Authority
- NO
- Norway
- Prior art keywords
- medicinal composition
- medicinal
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14091598 | 1998-05-22 | ||
| PCT/JP1999/002681 WO1999061061A1 (fr) | 1998-05-22 | 1999-05-21 | Composites medicamenteux |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005913D0 NO20005913D0 (no) | 2000-11-22 |
| NO20005913L true NO20005913L (no) | 2001-01-22 |
Family
ID=15279786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005913A NO20005913L (no) | 1998-05-22 | 2000-11-22 | Legemiddelsammensetning |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6835807B1 (no) |
| EP (1) | EP1080732A4 (no) |
| JP (1) | JP4560210B2 (no) |
| KR (1) | KR100581443B1 (no) |
| CN (1) | CN1250293C (no) |
| AU (1) | AU3733399A (no) |
| CA (1) | CA2333321A1 (no) |
| EA (1) | EA003398B1 (no) |
| HK (1) | HK1040052B (no) |
| NO (1) | NO20005913L (no) |
| TW (1) | TWI253935B (no) |
| WO (1) | WO1999061061A1 (no) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW527183B (en) | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
| WO2000025825A1 (en) | 1998-10-30 | 2000-05-11 | Daiichi Pharmaceutical Co., Ltd. | Dds compounds and method for assaying the same |
| US20030166513A1 (en) * | 2000-06-29 | 2003-09-04 | Akihiro Imura | Dds compound and process for the preparation thereof |
| TWI313609B (en) * | 2001-08-21 | 2009-08-21 | Mitsubishi Tanabe Pharma Corp | Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor |
| WO2004054622A1 (en) * | 2002-12-13 | 2004-07-01 | Immunomedics, Inc. | Immunoconjugates with an intracellularly-cleavable linkage |
| US7282590B2 (en) * | 2004-02-12 | 2007-10-16 | The Research Foundation Of State University Of New York | Drug conjugates |
| JP5064037B2 (ja) * | 2004-02-23 | 2012-10-31 | ジェネンテック， インコーポレイテッド | 複素環式自壊的リンカーおよび結合体 |
| JP2009508852A (ja) * | 2006-01-23 | 2009-03-05 | クワンジュ インスティチュート オブ サイエンス アンド テクノロジー | 薬理活性物質と粘膜粘着性高分子とが共有結合されたコンジュゲート及びこれを用いた薬理活性物質の経粘膜運搬方法 |
| CN1973902B (zh) * | 2006-12-12 | 2010-11-10 | 东北师范大学 | 以人参多糖为载体的抗肿瘤药物阿霉素复合物及制备方法 |
| US9789200B2 (en) | 2008-04-22 | 2017-10-17 | Fidia Farmaceutici S.P.A. | Therapeutic use of new pharmaceutical preparations containing antitumoral drugs bound to hyaluronic acid in the treatment of neoplasias |
| MX2012011901A (es) | 2010-04-15 | 2012-11-29 | Spirogen Sarl | Pirrolobenzodiacepinas y conjugados de las mismas. |
| US9895449B2 (en) | 2010-05-25 | 2018-02-20 | Syndevrx, Inc. | Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof |
| CN107141410B (zh) | 2010-05-25 | 2022-12-09 | 辛德弗雷克斯公司 | 聚合物缀合的MetAP2抑制剂及其应用的治疗方法 |
| CA2850371C (en) | 2011-10-14 | 2020-06-30 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
| KR102052774B1 (ko) | 2011-11-04 | 2019-12-04 | 자임워크스 인코포레이티드 | Ｆｃ 도메인 내의 돌연변이를 갖는 안정한 이종이합체 항체 설계 |
| WO2013177481A1 (en) | 2012-05-25 | 2013-11-28 | Immunogen, Inc. | Benzodiazepines and conjugates thereof |
| DK3342785T3 (da) | 2012-10-11 | 2020-03-23 | Daiichi Sankyo Co Ltd | Linker til antistof-lægemiddelkonjugat |
| BR112015008238A2 (pt) | 2012-10-12 | 2017-11-28 | Adc Therapeutics Sarl | conjugados de pirrolbenzodiazepina-anticorpo anti-cd22 |
| HUE039329T2 (hu) | 2012-10-12 | 2018-12-28 | Adc Therapeutics Sa | Pirrolobenzodiazepin-antitest konjugátumok |
| KR101645905B1 (ko) | 2012-10-12 | 2016-08-04 | 스피로즌 살 | 피롤로벤조디아제핀 및 그의 컨주게이트 |
| SMT201900017T1 (it) | 2012-10-12 | 2019-02-28 | Medimmune Ltd | Coniugati pirrolobenzodiazepina-anticorpo |
| SI2906253T1 (sl) | 2012-10-12 | 2018-11-30 | Adc Therapeutics Sa | Konjugati pirolobenzodiazepin-protitelo proti PSMA |
| WO2014057114A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-anti-psma antibody conjugates |
| ES2660029T3 (es) | 2012-10-12 | 2018-03-20 | Medimmune Limited | Conjugados de anticuerpo-pirrolobenzodiazepinas |
| JP6272230B2 (ja) * | 2012-10-19 | 2018-01-31 | 第一三共株式会社 | 親水性構造を含むリンカーで結合させた抗体−薬物コンジュゲート |
| US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
| CN105189507A (zh) | 2012-12-21 | 2015-12-23 | 斯皮罗根有限公司 | 吡咯并苯并二氮杂卓及其结合物 |
| MX363787B (es) | 2013-03-13 | 2019-04-03 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de los mismos. |
| WO2014140174A1 (en) | 2013-03-13 | 2014-09-18 | Spirogen Sàrl | Pyrrolobenzodiazepines and conjugates thereof |
| CA2904044C (en) | 2013-03-13 | 2020-03-31 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| US9173956B2 (en) | 2013-04-10 | 2015-11-03 | Syndevrx, Inc. | METAP2 inhibitors and methods of treating obesity |
| WO2015052535A1 (en) | 2013-10-11 | 2015-04-16 | Spirogen Sàrl | Pyrrolobenzodiazepine-antibody conjugates |
| GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
| EP3054983B1 (en) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| EP3054985B1 (en) | 2013-10-11 | 2018-12-26 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| DK3088419T3 (en) | 2013-12-25 | 2019-01-28 | Daiichi Sankyo Co Ltd | ANTI-TROP2 ANTIBODY-MEDICINE CONJUGATE |
| PT3101032T (pt) * | 2014-01-31 | 2019-04-03 | Daiichi Sankyo Co Ltd | Onjugado de anticorpo anti-her2-fármaco |
| US10550190B2 (en) | 2014-04-04 | 2020-02-04 | Merck Sharp & Dohme Corp. | Phosphate based linkers for intracellular delivery of drug conjugates |
| EP3130608B1 (en) * | 2014-04-10 | 2019-09-04 | Daiichi Sankyo Co., Ltd. | (anti-her2 antibody)-drug conjugate |
| TWI874265B (zh) | 2014-04-10 | 2025-02-21 | 日商第一三共股份有限公司 | 抗her3抗體-藥物結合物之用途 |
| GB201406767D0 (en) | 2014-04-15 | 2014-05-28 | Cancer Rec Tech Ltd | Humanized anti-Tn-MUC1 antibodies anf their conjugates |
| EP3193940A1 (en) | 2014-09-10 | 2017-07-26 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| MX379396B (es) | 2014-11-25 | 2025-03-11 | Adc Therapeutics Sa | Conjugados de pirrolobenzodiazepina y anticuerpo. |
| CA2982205A1 (en) | 2015-04-10 | 2016-10-13 | David W. Andrews | Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory m2 monocytes |
| GB201506389D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| EP4180455A1 (en) | 2015-06-29 | 2023-05-17 | Daiichi Sankyo Company, Limited | Method for selectively manufacturing antibody-drug conjugate |
| EP3359191A4 (en) | 2015-10-05 | 2019-05-29 | Merck Sharp & Dohme Corp. | ANTIBODY PEPTIDE CONJUGATES WITH AGONISTEACTIVITY ON GLUCAGON RECEPTORS AND GLUCAGON-LIKE PEPTIDE-1 |
| EP3359194A4 (en) | 2015-10-06 | 2019-04-24 | Merck Sharp & Dohme Corp. | ANTIBODY-ACTIVE CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS |
| CN108290853B (zh) | 2015-12-10 | 2022-05-31 | 辛德弗雷克斯公司 | 烟曲霉醇衍生物及其多晶型物 |
| AU2017206718B2 (en) | 2016-01-11 | 2021-09-30 | Syndevrx, Inc. | Treatment for tumors driven by metabolic dysfunction |
| GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
| WO2017132103A2 (en) | 2016-01-29 | 2017-08-03 | Merck Sharp & Dohme Corp. | Phosphonate linkers and their use to facilitate cellular retention of compounds |
| GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| TWI862473B (zh) | 2016-12-12 | 2024-11-21 | 日商第一三共股份有限公司 | 抗體-藥物結合物與免疫檢查點抑制劑之組合、以及醫藥組成物之用途 |
| WO2018135501A1 (ja) | 2017-01-17 | 2018-07-26 | 第一三共株式会社 | 抗ｇｐｒ２０抗体及び抗ｇｐｒ２０抗体－薬物コンジュゲート |
| GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
| US11160872B2 (en) | 2017-02-08 | 2021-11-02 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
| WO2018192944A1 (en) | 2017-04-18 | 2018-10-25 | Medimmune Limited | Pyrrolobenzodiazepine conjugates |
| CA3057748A1 (en) | 2017-04-20 | 2018-10-25 | Adc Therapeutics Sa | Combination therapy with an anti-axl antibody-drug conjugate |
| TW202532104A (zh) | 2017-05-15 | 2025-08-16 | 日商第一三共股份有限公司 | 抗體－藥物結合物及其用途 |
| KR102442736B1 (ko) | 2017-06-14 | 2022-09-16 | 에이디씨 테라퓨틱스 에스에이 | 항-cd19 adc의 투여를 위한 투약량 체제 |
| SG11202000358YA (en) | 2017-08-18 | 2020-02-27 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| AU2018327171B2 (en) | 2017-08-31 | 2023-03-09 | Daiichi Sankyo Company, Limited | Improved method for producing antibody-drug conjugate |
| CN111065621B (zh) | 2017-08-31 | 2024-01-26 | 第一三共株式会社 | 制备抗体-药物缀合物的新方法 |
| AU2018354189A1 (en) | 2017-10-24 | 2020-04-23 | Crispr Therapeutics Ag | Compositions and methods for the depletion of CD117+ cells |
| WO2019108863A1 (en) | 2017-11-29 | 2019-06-06 | Magenta Therapeutics, Inc. | Compositions and methods for the depletion of cd5+ cells |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| SI3794042T1 (sl) | 2018-05-18 | 2024-07-31 | Daiichi Sankyo Co., Ltd. | Konjugat protitelesa anti-MUC1-exatecan in citotoksično sredstvo |
| CN112739340B (zh) | 2018-07-23 | 2025-05-13 | 海德堡医药研究有限责任公司 | 抗cd5抗体药物缀合物(adc)在同种异体细胞疗法中的用途 |
| CN112533958B (zh) | 2018-07-27 | 2024-11-15 | 第一三共株式会社 | 识别抗体-药物缀合物的药物部分的蛋白 |
| CA3108044A1 (en) | 2018-07-31 | 2020-02-06 | Daiichi Sankyo Company, Limited | Treatment of metastatic brain tumor by administration of antibody-drug conjugate |
| AU2019366819B2 (en) | 2018-10-26 | 2025-08-21 | Syndevrx Inc. | Biomarkers of MetAP2 inhibitors and applications thereof |
| JP7520870B2 (ja) | 2019-03-15 | 2024-07-23 | メドイミューン・リミテッド | がんの治療における使用のための、アゼチドベンゾジアゼピン二量体及びこれを含む複合体 |
| US20200407440A1 (en) | 2019-04-24 | 2020-12-31 | Magenta Therapeutics, Inc. | Amatoxin antibody-drug conjugates and uses thereof |
| GB201908128D0 (en) | 2019-06-07 | 2019-07-24 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
| CN110339181A (zh) * | 2019-07-02 | 2019-10-18 | 中国药科大学 | 一种基于点击反应的pH响应型纳米制剂及其制法和应用 |
| PE20220563A1 (es) | 2019-07-10 | 2022-04-13 | Cybrexa 2 Inc | Conjugados peptidicos de citotoxinas como terapeuticos |
| JP7675060B2 (ja) | 2019-07-10 | 2025-05-12 | サイブレクサ ３，インコーポレイテッド | 治療薬としての微小管標的化剤のペプチドコンジュゲート |
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| WO2022043256A1 (en) | 2020-08-23 | 2022-03-03 | Cobiores Nv | Synergistic combinations of anticancer drugs linked to a tetrapeptidic moiety and immunotherapeutic agents |
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| AU2021387795A1 (en) | 2020-11-25 | 2023-06-01 | Innate Pharma | Treatment of cancer |
| CA3203072A1 (en) | 2020-12-22 | 2022-06-30 | Andrea CASAZZA | Compounds comprising a tetrapeptidic moiety |
| WO2022167664A1 (en) | 2021-02-07 | 2022-08-11 | Cobiores Nv | Compounds comprising a tetrapeptidic moiety |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| CN119156231A (zh) | 2022-04-07 | 2024-12-17 | 海德堡医药研究有限责任公司 | 提高鹅膏蕈毒素-抗体缀合物的治疗指数的方法 |
| JP2025517476A (ja) | 2022-05-25 | 2025-06-05 | イナート・ファルマ・ソシエテ・アノニム | ネクチン－４結合剤 |
| WO2024121632A1 (en) | 2022-12-09 | 2024-06-13 | Crispr Therapeutics Ag | Use of anti-cd117 antibody drug conjugate (adc) |
| CN120936385A (zh) | 2023-03-13 | 2025-11-11 | 海德堡医药研究有限责任公司 | 用于在癌症治疗中使用的皮下施用的抗体-药物缀合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992014759A1 (fr) | 1991-02-21 | 1992-09-03 | Drug Delivery System Institute, Ltd. | Carboxymethylmannoglucane et derive |
| JP3359955B2 (ja) * | 1992-07-16 | 2002-12-24 | 第一製薬株式会社 | 抗腫瘍剤 |
| ATE195324T1 (de) * | 1993-02-26 | 2000-08-15 | Drug Delivery System Inst Ltd | Polysaccharidderivat und wirkstoffträger |
| US6214345B1 (en) * | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| JPH0784481A (ja) | 1993-06-26 | 1995-03-31 | Ricoh Co Ltd | 画像形成装置 |
| CA2192725C (en) | 1995-12-28 | 2004-04-20 | Kenji Tsujihara | Camptothecin derivatives |
| TW409058B (en) * | 1996-06-06 | 2000-10-21 | Daiichi Seiyaku Co | Method for preparation of a drug complex |
| TW527183B (en) * | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
| US6368598B1 (en) * | 1996-09-16 | 2002-04-09 | Jcrt Radiation Oncology Support Services, Inc. | Drug complex for treatment of metastatic prostate cancer |
| CA2264227A1 (en) | 1996-09-27 | 1998-04-02 | Raymond A. Firestone | Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells |
| EP0941120A4 (en) * | 1996-11-05 | 2004-08-18 | Bristol Myers Squibb Co | BRANCHED PEPTIDLINKERS |
| JPH1171280A (ja) | 1997-06-26 | 1999-03-16 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
| JPH1192405A (ja) | 1997-09-19 | 1999-04-06 | Dai Ichi Seiyaku Co Ltd | 薬物複合体 |
| WO2000025825A1 (en) * | 1998-10-30 | 2000-05-11 | Daiichi Pharmaceutical Co., Ltd. | Dds compounds and method for assaying the same |
-
1999
- 1999-05-21 TW TW088108351A patent/TWI253935B/zh not_active IP Right Cessation
- 1999-05-21 EP EP99919664A patent/EP1080732A4/en not_active Withdrawn
- 1999-05-21 CA CA002333321A patent/CA2333321A1/en not_active Abandoned
- 1999-05-21 CN CNB998089796A patent/CN1250293C/zh not_active Expired - Fee Related
- 1999-05-21 AU AU37333/99A patent/AU3733399A/en not_active Abandoned
- 1999-05-21 WO PCT/JP1999/002681 patent/WO1999061061A1/ja not_active Ceased
- 1999-05-21 HK HK02101369.9A patent/HK1040052B/zh not_active IP Right Cessation
- 1999-05-21 KR KR1020007013102A patent/KR100581443B1/ko not_active Expired - Fee Related
- 1999-05-21 JP JP2000550520A patent/JP4560210B2/ja not_active Expired - Fee Related
- 1999-05-21 US US09/674,526 patent/US6835807B1/en not_active Expired - Fee Related
- 1999-05-21 EA EA200001217A patent/EA003398B1/ru not_active IP Right Cessation
-
2000
- 2000-11-22 NO NO20005913A patent/NO20005913L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100581443B1 (ko) | 2006-05-23 |
| AU3733399A (en) | 1999-12-13 |
| JP4560210B2 (ja) | 2010-10-13 |
| CN1250293C (zh) | 2006-04-12 |
| CN1310631A (zh) | 2001-08-29 |
| US6835807B1 (en) | 2004-12-28 |
| EA003398B1 (ru) | 2003-04-24 |
| EP1080732A1 (en) | 2001-03-07 |
| TWI253935B (en) | 2006-05-01 |
| HK1040052B (zh) | 2006-09-15 |
| CA2333321A1 (en) | 1999-12-02 |
| WO1999061061A1 (fr) | 1999-12-02 |
| KR20010052385A (ko) | 2001-06-25 |
| EA200001217A1 (ru) | 2001-06-25 |
| EP1080732A4 (en) | 2004-08-25 |
| HK1040052A1 (en) | 2002-05-24 |
| NO20005913D0 (no) | 2000-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |