DK0738107T3 - Inhibitorer for fedtsyresyntese som antimikrobielle midler - Google Patents

Inhibitorer for fedtsyresyntese som antimikrobielle midler

Info

Publication number
DK0738107T3
DK0738107T3 DK95909239T DK95909239T DK0738107T3 DK 0738107 T3 DK0738107 T3 DK 0738107T3 DK 95909239 T DK95909239 T DK 95909239T DK 95909239 T DK95909239 T DK 95909239T DK 0738107 T3 DK0738107 T3 DK 0738107T3
Authority
DK
Denmark
Prior art keywords
fatty acid
acid synthesis
inhibitors
fas
cells
Prior art date
Application number
DK95909239T
Other languages
Danish (da)
English (en)
Inventor
D Dick James
P Kuhajda Francis
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of DK0738107T3 publication Critical patent/DK0738107T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK95909239T 1994-01-24 1995-01-24 Inhibitorer for fedtsyresyntese som antimikrobielle midler DK0738107T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/188,421 US5614551A (en) 1994-01-24 1994-01-24 Inhibitors of fatty acid synthesis as antimicrobial agents
PCT/US1995/000544 WO1995019706A1 (fr) 1994-01-24 1995-01-24 Inhibiteurs de la synthese des acides gras a titre d'agents antimicrobiens

Publications (1)

Publication Number Publication Date
DK0738107T3 true DK0738107T3 (da) 2003-01-06

Family

ID=22693071

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95909239T DK0738107T3 (da) 1994-01-24 1995-01-24 Inhibitorer for fedtsyresyntese som antimikrobielle midler

Country Status (13)

Country Link
US (1) US5614551A (fr)
EP (1) EP0738107B1 (fr)
JP (1) JPH09508370A (fr)
KR (1) KR100395601B1 (fr)
AT (1) ATE223215T1 (fr)
AU (1) AU703272B2 (fr)
CA (1) CA2181031A1 (fr)
DE (1) DE69528039T2 (fr)
DK (1) DK0738107T3 (fr)
ES (1) ES2182888T3 (fr)
MX (1) MX9602934A (fr)
PT (1) PT738107E (fr)
WO (1) WO1995019706A1 (fr)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010881A (en) * 1996-02-20 2000-01-04 Smithkline Beecham Corporation RibG
US5859027A (en) * 1996-02-26 1999-01-12 Chektec Corporation Antimicrobial agent
US5910509A (en) * 1996-06-20 1999-06-08 Broedel; Sheldon E. Antimicrobial agent for agriculture
WO1998003661A2 (fr) * 1996-07-19 1998-01-29 Arch Development Corporation Agents antimicrobiens, reactifs de diagnostic et vaccins a base de composants specifiques du parasite apicomplexan
US5750496A (en) * 1996-08-12 1998-05-12 Utah State University Method of controlling cryptosporidium infectons using protease inhibitors
WO1998006734A1 (fr) * 1996-08-16 1998-02-19 Smithkline Beecham Corporation Nouveaux polynucleotides et polypeptides procaryotes et leurs utilisations
US20050112713A1 (en) * 1996-08-28 2005-05-26 Affinium Pharmaceuticals, Inc. Methods of using Fab I and compounds modulating Fab I activity
US6995254B1 (en) 1996-08-28 2006-02-07 Affinium Pharmaceuticals, Inc. Polynucleotide encoding the enoyl-acyl carrier protein reductase of Staphylococcus aureus, FAB I
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass
US5859028A (en) * 1997-04-28 1999-01-12 Potomax Limited Partnership Carotenoid synthesis inhibiting herbicides and fatty acid synthesis inhibiting oxime herbicides as anti-Apicomplexa protozoan parasite agents
US6171856B1 (en) 1997-07-30 2001-01-09 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
WO1999010321A2 (fr) * 1997-08-29 1999-03-04 The Johns Hopkins University Composes antimicrobiens
US6713654B1 (en) 1997-08-29 2004-03-30 The Johns Hopkins University School Of Medicine Antimicrobial compounds
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
AR024158A1 (es) 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
US7303526B2 (en) * 1999-08-09 2007-12-04 Cardiokinetix, Inc. Device for improving cardiac function
EP1206463A4 (fr) * 1999-08-23 2003-01-29 Smithkline Beecham Corp Inhibiteurs de synthase d'acide gras
EP1226138B1 (fr) * 1999-10-08 2004-12-29 Affinium Pharmaceuticals, Inc. Inhibiteurs de fab i
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
WO2001030988A1 (fr) * 1999-10-27 2001-05-03 Smithkline Beecham Corporation Procedes de fabrication et d'utilisation de reactifs de voies de synthese d'acides gras
US6951729B1 (en) 1999-10-27 2005-10-04 Affinium Pharmaceuticals, Inc. High throughput screening method for biological agents affecting fatty acid biosynthesis
US6656703B1 (en) * 1999-12-29 2003-12-02 Millennium Pharamaceuticals, Inc. High throughput screen for inhibitors of fatty acid biosynthesis in bacteria
AU2761101A (en) * 2000-01-07 2001-07-24 Virginia Commonwealth University A scintillation proximity assay for type ii fatty acid biosynthetic enzymes
WO2001060174A2 (fr) * 2000-02-16 2001-08-23 The Johns Hopkins University School Of Medicine Perte de poids induite par la reduction du niveau de neuropeptide y
US20040157918A1 (en) * 2001-02-16 2004-08-12 Loftus Thomas M. Weight loss induced by reduction in neuropeptide y level
WO2001071045A2 (fr) * 2000-03-23 2001-09-27 Millennium Pharmaceuticals, Inc. Criblage a debit eleve relatif a des inhibiteurs de la synthese d'acides gras, d'ergosterols, de sphingolipides ou de phospholipides dans des champignons
US7048926B2 (en) * 2000-10-06 2006-05-23 Affinium Pharmaceuticals, Inc. Methods of agonizing and antagonizing FabK
DK1560584T3 (da) * 2001-04-06 2009-05-18 Affinium Pharm Inc Fab I inhibitorer
US6821999B2 (en) * 2001-11-21 2004-11-23 Kimberly-Clark Worldwide, Inc. Methods for inhibiting the production of TSST-1
US7348023B2 (en) * 2001-11-21 2008-03-25 Kimberly-Clark Worldwide, Inc. Absorbent articles containing additives
US7323186B2 (en) * 2001-11-21 2008-01-29 Kimberly-Clark Worldwide, Inc. Non-absorbent articles containing additives
US6955890B2 (en) * 2002-02-14 2005-10-18 Pyro Pharmaceuticals, Inc. Method for the identification and treatment of pathogenic microorganisms infections by inhibiting one or more enzymes in an essential metabolic pathway
US20060063224A1 (en) * 2002-05-10 2006-03-23 Schechter Alan M Method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in an essential metabolic pathway
CA2491802C (fr) 2002-07-09 2012-04-10 Fasgen, Inc. Nouveaux composes, compositions pharmaceutiques les contenant et methodes d'utilisation desdits composes
DK1575951T3 (da) * 2002-12-06 2014-09-15 Debiopharm Int Sa Heterocykliske forbindelser, fremgangsmåder til fremstilling deraf og deres anvendelse i terapi
EP1608377B1 (fr) 2003-03-17 2008-10-01 Affinium Pharmaceuticals, Inc. Compositions comportant plusieurs agents antibiotiques, et leurs procedes de mise en oeuvre
WO2005005469A2 (fr) * 2003-07-11 2005-01-20 Affinium Pharmaceuticals, Inc. Nouveaux polypeptides purifies provenant du staphylocoque dore
RU2006146051A (ru) * 2004-05-26 2008-07-10 Фасджен Новые соединения, фармацевтические композиции на их основе и способы применения
DK1828167T3 (da) * 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
CA2632476A1 (fr) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Agents therapeutiques et ses procedes de fabrication et d'utilisation
EP1991213A2 (fr) * 2006-02-08 2008-11-19 Fasgen, Inc. Formulation anti-mycobactérienne comprenant de l' octanesulfonylacetamide (osa), du decanesulfonylacetamide
JP5468899B2 (ja) * 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
WO2008098374A1 (fr) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Sels, promédicaments et polymorphes d'inhibiteurs de fab 1
CN101820757A (zh) 2007-06-01 2010-09-01 普林斯顿大学托管委员会 通过调节宿主细胞代谢途径治疗病毒感染
US8729239B2 (en) 2009-04-09 2014-05-20 Nuclea Biotechnologies, Inc. Antibodies against fatty acid synthase
ES2731474T3 (es) 2012-06-19 2019-11-15 Debiopharm Int Sa Derivados de profármaco de (E)-N-metil-N-((3-metilbenzofuran-2-il)metil)-3-(7-oxo-5,6,7,8-tetrahidro-1,8-naftiridin-3-il)acrilamida
BR102012033811A8 (pt) * 2012-12-28 2019-12-24 Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha
BR102013006007A2 (pt) * 2013-03-13 2014-11-11 Ubea Compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha a partir de derivados de acetamida, ureia, fenol e carboxamida
EP3419628B1 (fr) 2016-02-26 2020-10-14 Debiopharm International SA Médicament pour le traitement des infections diabétiques du pied
EP3266454A1 (fr) * 2016-07-07 2018-01-10 Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften Inhibiteurs d'acc pour leur utilisation dans le traitement de maladies mycobactériennes
US20210290629A1 (en) * 2016-07-07 2021-09-23 Forschungzentrum Borstel Leibniz-Zentrum fuer Medizin und Biowissenschaften Acc inhibitors for use in treating mycobacterial diseases
US20210137934A1 (en) * 2017-03-16 2021-05-13 The Board Of Trustees Of The Leland Stanford Junior University Methods of identifying myc-driven and lipogenesis-dependent neoplasms and methods of treating the same

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE252616C (de) * 1912-01-25 1912-10-23 Gebr Lesser Ablegerad für Kartoffelerntemaschinen mit einem quer zur Fahrrichtung de Maschine umlaufenden Wurfrad
US3535309A (en) * 1967-09-01 1970-10-20 Kitasato Inst Antibiotics and their production
US3630846A (en) * 1967-09-01 1971-12-28 Kitasato Inst And Toyo Jozo Kk Antibiotic production using streptomyces kitasatoensis
US3909361A (en) * 1971-06-29 1975-09-30 Nihon Tokushu Noyaku Seizo Kk Novel antifungal antibiotic substance, process for production of the same, and agricultural and horticultural fungicidal composition containing said substance
JPS5619344B2 (fr) * 1972-11-11 1981-05-07
US4032647A (en) * 1975-06-16 1977-06-28 Richardson-Merrell Inc. Substituted thenoylacetic acid and esters
US4738984A (en) * 1973-04-02 1988-04-19 Merrell Dow Pharmaceuticals Inc. Antirhinovirus agents
US4000164A (en) * 1973-04-02 1976-12-28 Richardson-Merrell Inc. Hypolipidemic agents
US4602099A (en) * 1973-04-02 1986-07-22 Merrell Dow Pharmaceuticals Inc. Antirhinovirus agents
US4110351A (en) * 1973-04-02 1978-08-29 Richardson-Merrell Inc. Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts
US4011334A (en) * 1975-10-03 1977-03-08 Richardson-Merrell Inc. Use of substituted furan and thiophene carboxaldehydes as hypolipidemic agents
US4328246A (en) * 1979-08-14 1982-05-04 Joseph Gold Anti Walker 256 carcinoma agent and combination thereof
JPS59225115A (ja) * 1983-06-06 1984-12-18 Ota Seiyaku Kk 青魚類から得た長鎖高度不飽和脂肪酸を含有する微細カプセル
JPS6058917A (ja) * 1983-09-09 1985-04-05 Rikagaku Kenkyusho 制癌剤
FR2552879B1 (fr) * 1983-10-03 1987-08-14 Pasteur Institut Procede et reactifs pour la detection d'une anomalie genetique dans une matiere biologique, notamment dans une preparation de leucocytes
CA1256372A (fr) * 1985-04-11 1989-06-27 Koichiro Miyazima Procede de production de composes de liposomes
US5110731A (en) * 1985-08-26 1992-05-05 Amgen, Inc. System for biotin synthesis
US4789630A (en) * 1985-10-04 1988-12-06 Cetus Corporation Ionic compounds containing the cationic meriquinone of a benzidine
GB8607137D0 (en) * 1986-03-21 1986-04-30 Efamol Ltd Compositions
US4968494A (en) * 1987-03-27 1990-11-06 Merck & Co., Inc. Methods and compositions for thrombolytic therapy
US5188830A (en) * 1987-03-27 1993-02-23 Merck & Co., Inc. Methods for thrombolytic therapy
US5185149A (en) * 1987-03-27 1993-02-09 Merck & Co., Inc. Methods for thrombolytic therapy
JPH01132542A (ja) * 1987-11-19 1989-05-25 Toomen:Kk ゴッシポールラセミ体の光学分割法
US4877782A (en) * 1988-02-16 1989-10-31 The Upjohn Company Zinc ceftiofur complexes
JPH02113850A (ja) * 1988-10-21 1990-04-26 Nippon Oil & Fats Co Ltd 発癌抑制用油脂組成物
US5190969A (en) * 1988-12-20 1993-03-02 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services 2,3-epoxy derivatives as anti retrovital chemotherapeutic agents
AU621434B2 (en) * 1988-12-21 1992-03-12 Merrell Dow Pharmaceuticals Inc. Antiretroviral furan ketones
JPH02247125A (ja) * 1989-03-17 1990-10-02 Koken Kk 悪性腫瘍細胞増殖抑制剤
US5143907A (en) * 1991-05-10 1992-09-01 Boron Biologicals, Inc. Phosphite-borane compounds, and method of making and using the same
US5858784A (en) * 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
AU3467193A (en) * 1991-12-17 1993-07-19 Regents Of The University Of California, The Gene therapy for cystic fibrosis transmembrane conductance regulator activity (CFTR)
DE69332353T2 (de) * 1992-07-24 2003-07-10 The Johns Hopkins University, Baltimore Verwendung von inhibitoren der synthese von fettsäuren zur behandlung von krebs
US5539132A (en) * 1994-01-24 1996-07-23 Johns Hopkins University Cerulenin compounds for fatty acid synthesis inhibition

Also Published As

Publication number Publication date
EP0738107B1 (fr) 2002-09-04
US5614551A (en) 1997-03-25
DE69528039T2 (de) 2003-08-07
MX9602934A (es) 1997-12-31
AU1726895A (en) 1995-08-08
AU703272B2 (en) 1999-03-25
ATE223215T1 (de) 2002-09-15
WO1995019706A1 (fr) 1995-07-27
CA2181031A1 (fr) 1995-07-27
EP0738107A4 (fr) 1998-09-09
ES2182888T3 (es) 2003-03-16
DE69528039D1 (de) 2002-10-10
KR100395601B1 (ko) 2003-11-17
EP0738107A1 (fr) 1996-10-23
JPH09508370A (ja) 1997-08-26
PT738107E (pt) 2003-01-31

Similar Documents

Publication Publication Date Title
DK0738107T3 (da) Inhibitorer for fedtsyresyntese som antimikrobielle midler
WO2002053101A3 (fr) Procede de traitement de troubles fibrogenes et autres symptomes de type ivc
ATE238783T1 (de) Mikrobenbeständige und stabilisierte lösungen, die gamma-hydroxybuttersäuresalze zur behandlung von narkolepsie enthalten
AU2005202257C1 (en) Azacyclic compounds for use in the treatment of serotonin related diseases
NZ515567A (en) Method for treating chronic pain using MEK inhibitors
AU2002238737A1 (en) Glycyrrhetinic acid derivatives, progesterone and progesterone derivatives and their use for the manufacture of a medicament to inhibit 11beta-hydroxysteroid dehydrogenase activity
ATE225167T1 (de) Verwendung von inhibitoren der synthese von fettsäuren zur behandlung von krebs
NO20014241D0 (no) C16-umettede FP-selektive prostaglandinanaloger
ATE402257T1 (de) Antisense gegen c-myc zur behandlung von polyzystischer nierenkrankheit
AU2001245319A1 (en) Methods of treating diseases with activated protein c
MXPA03005922A (es) Metodo para tratar glaucoma ib.
DE50100833D1 (de) Verwendung von 2-methyl-thiazolidin-2,4-dicarbonsäure und / oder ihrer physiologisch verträglichen salze zur herstellung eines medikaments zur behandlung von krebserkrankungen
WO2002067851A3 (fr) Procede de traitement ou d'amelioration de maladies fibreuses ou autres etats iiic
MD1585F1 (en) Biostimulating remedy
NO20032411L (no) Anvendelse av substituerte 6-dimetylaminometyl-1-fenyl- cykloheksan-forbindelser for behandling av urininkontinens
AU2900100A (en) Methods for inhibiting cathepsin k activity for the treatment of diseases related to bone loss
HUP9801925A1 (hu) Nátrium/hidrogén-csere inhibítorok alkalmazása protozoák által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására
BR0316245A (pt) Atividade antimicrobiana de espécie de oxigênio reativo produtora de anticorpos
DE69630523D1 (de) Verwendung von Calciumkanalanantagonisten zur Behandlung von Herz-, Nieren-, Magen-und Darmkrankheiten sowie Bluthochdruck
BRPI0416755A (pt) uso de inibidores de catepsina k para o tratamento de doenças de perda óssea severa
SE9903610D0 (sv) Novel compounds II
TW200503624A (en) Preventive for plant disease and a method for preventing plant disease using the same
DE602004015831D1 (de) Verwendung von idrocilamid zur herstellung einer pharmazeutischen zusammensetzung zur behandlung von rosacea
PL356931A1 (en) Use of natural compounds having antiangiogenic activity
SE9903609D0 (sv) Novel compounds I