BR102012033811A8 - compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha - Google Patents

compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha Download PDF

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Publication number
BR102012033811A8
BR102012033811A8 BR102012033811A BR102012033811A BR102012033811A8 BR 102012033811 A8 BR102012033811 A8 BR 102012033811A8 BR 102012033811 A BR102012033811 A BR 102012033811A BR 102012033811 A BR102012033811 A BR 102012033811A BR 102012033811 A8 BR102012033811 A8 BR 102012033811A8
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BR
Brazil
Prior art keywords
yeast
microorganisms
compounds
ligand
pharmaceutical composition
Prior art date
Application number
BR102012033811A
Other languages
English (en)
Other versions
BR102012033811A2 (pt
Inventor
Valim Bizarro Cristiano
Pauli Ivani
Augusto Basso Luiz
Norberto De Souza Osmar
Machado Pablo
Original Assignee
Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs filed Critical Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs
Priority to BR102012033811A priority Critical patent/BR102012033811A8/pt
Priority to PCT/BR2013/000610 priority patent/WO2014100881A1/pt
Publication of BR102012033811A2 publication Critical patent/BR102012033811A2/pt
Publication of BR102012033811A8 publication Critical patent/BR102012033811A8/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha. a presente invenção apresenta novos e inventivos compostos inibidores enzimáticos em microorganismos. em uma realização preferencial, os compostos da presente invenção são utilizados para inibir a enzima 2-transenoil-acp (coa) redutase em microorganismos.
BR102012033811A 2012-12-28 2012-12-28 compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha BR102012033811A8 (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BR102012033811A BR102012033811A8 (pt) 2012-12-28 2012-12-28 compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha
PCT/BR2013/000610 WO2014100881A1 (pt) 2012-12-28 2013-12-27 Compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102012033811A BR102012033811A8 (pt) 2012-12-28 2012-12-28 compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha

Publications (2)

Publication Number Publication Date
BR102012033811A2 BR102012033811A2 (pt) 2014-08-26
BR102012033811A8 true BR102012033811A8 (pt) 2019-12-24

Family

ID=51019590

Family Applications (1)

Application Number Title Priority Date Filing Date
BR102012033811A BR102012033811A8 (pt) 2012-12-28 2012-12-28 compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha

Country Status (2)

Country Link
BR (1) BR102012033811A8 (pt)
WO (1) WO2014100881A1 (pt)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
FR2927331B1 (fr) * 2008-02-07 2011-05-20 Centre Nat Rech Scient Nouveaux derives anti-infectieux, leur procede de preparation, compositions pharmaceutiques les contenant et leurs utilisations en therapeutique.

Also Published As

Publication number Publication date
BR102012033811A2 (pt) 2014-08-26
WO2014100881A1 (pt) 2014-07-03

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07C Technical examination (opinion): republication [chapter 7.3 patent gazette]

Free format text: REF. A RPI NO 2496 DE 06/11/2018.

B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B03H Publication of an application: rectification [chapter 3.8 patent gazette]

Free format text: RTIFICADO O DESPACHO 3.1 PUBLICADO NA RPI 2277 DE 26/08/2014 SOB O ITEM (72) DEVIDO A PETICAO 870190128580 DE 05/12/2019.

B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal: appeal against refusal