DK0723146T3 - Opkonverterende reportermolekyler til biologiske og andre assays ved anvendelse af laser-excitationsteknikker - Google Patents
Opkonverterende reportermolekyler til biologiske og andre assays ved anvendelse af laser-excitationsteknikkerInfo
- Publication number
- DK0723146T3 DK0723146T3 DK96200682T DK96200682T DK0723146T3 DK 0723146 T3 DK0723146 T3 DK 0723146T3 DK 96200682 T DK96200682 T DK 96200682T DK 96200682 T DK96200682 T DK 96200682T DK 0723146 T3 DK0723146 T3 DK 0723146T3
- Authority
- DK
- Denmark
- Prior art keywords
- biological
- upconverting
- assays
- analytes
- reporter molecules
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
- G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00617—Delimitation of the attachment areas by chemical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6419—Excitation at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Nanotechnology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Transplantation (AREA)
- Optics & Photonics (AREA)
- Materials Engineering (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94606892A | 1992-09-14 | 1992-09-14 | |
EP93921595A EP0660936B1 (en) | 1992-09-14 | 1993-09-14 | Up-converting reporters for biological and other assays using laser excitation techniques |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0723146T3 true DK0723146T3 (da) | 2004-08-30 |
Family
ID=25483910
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93921595T DK0660936T3 (da) | 1992-09-14 | 1993-09-14 | Op-konverterende reportermolekyle til biologiske og andre assays under anvendelse af laserexcitationsteknik |
DK96200682T DK0723146T3 (da) | 1992-09-14 | 1993-09-14 | Opkonverterende reportermolekyler til biologiske og andre assays ved anvendelse af laser-excitationsteknikker |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93921595T DK0660936T3 (da) | 1992-09-14 | 1993-09-14 | Op-konverterende reportermolekyle til biologiske og andre assays under anvendelse af laserexcitationsteknik |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP1333274B1 (ja) |
JP (3) | JP3420765B2 (ja) |
AT (3) | ATE266195T1 (ja) |
CA (1) | CA2144527C (ja) |
DE (3) | DE69333502T2 (ja) |
DK (2) | DK0660936T3 (ja) |
ES (2) | ES2216034T3 (ja) |
WO (1) | WO1994007142A1 (ja) |
Families Citing this family (118)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994007138A1 (en) | 1992-09-14 | 1994-03-31 | Fodstad Oystein | Detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations |
NO180658C (no) | 1994-03-10 | 1997-05-21 | Oeystein Fodstad | Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner |
US5891738A (en) * | 1995-01-16 | 1999-04-06 | Erkki Soini | Biospecific multiparameter assay method |
FI101829B (fi) * | 1995-03-07 | 1998-08-31 | Erkki Juhani Soini | Biospesifinen määritysmenetelmä |
FI98765C (fi) | 1995-01-16 | 1997-08-11 | Erkki Soini | Virtaussytometrinen menetelmä ja laite |
US5912257A (en) * | 1995-09-06 | 1999-06-15 | The Research Foundation Of State University Of New York | Two-photon upconverting dyes and applications |
NO961031D0 (no) | 1996-03-13 | 1996-03-13 | Det Norske Radiumshospital Tum | Fremgangsmåte til å drepe uönskede målceller |
US7144119B2 (en) | 1996-04-25 | 2006-12-05 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US6251691B1 (en) | 1996-04-25 | 2001-06-26 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
US6958245B2 (en) | 1996-04-25 | 2005-10-25 | Bioarray Solutions Ltd. | Array cytometry |
DE69732510T2 (de) * | 1996-10-31 | 2005-08-25 | Fuji Photo Film Co., Ltd., Minami-Ashigara | Bilderzeugende Vorrichtung |
US6310354B1 (en) | 1996-12-03 | 2001-10-30 | Erkki Soini | Method and a device for monitoring nucleic acid amplification reactions |
JP3761898B2 (ja) * | 1996-12-03 | 2006-03-29 | ソイニ,エルッキ | 生体特異性二光子励起蛍光検出方法およびそのための装置 |
NO308755B1 (no) * | 1996-12-20 | 2000-10-23 | Iystein Fodstad | FremgangsmÕte til karakterisering av unormale celler, anvendelse og sett for utførelse av fremgangsmÕten |
US5827748A (en) * | 1997-01-24 | 1998-10-27 | The United States Of America As Represented By The Secretary Of The Navy | Chemical sensor using two-dimensional lens array |
US20030027126A1 (en) | 1997-03-14 | 2003-02-06 | Walt David R. | Methods for detecting target analytes and enzymatic reactions |
US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
US7622294B2 (en) | 1997-03-14 | 2009-11-24 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
EP0968411A1 (en) * | 1997-03-25 | 2000-01-05 | Photonic Research Systems Limited | Luminescence assays |
US6406845B1 (en) | 1997-05-05 | 2002-06-18 | Trustees Of Tuft College | Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample |
WO1998053093A1 (en) | 1997-05-23 | 1998-11-26 | Bioarray Solutions Llc | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
DE19725050C2 (de) * | 1997-06-13 | 1999-06-24 | Fraunhofer Ges Forschung | Anordnung zur Detektion biochemischer oder chemischer Substanzen mittels Fluoreszenzlichtanregung und Verfahren zu deren Herstellung |
GB9718477D0 (en) * | 1997-09-02 | 1997-11-05 | Photonic Research Systems Limi | Luminescence detection |
US7348181B2 (en) | 1997-10-06 | 2008-03-25 | Trustees Of Tufts College | Self-encoding sensor with microspheres |
US7115884B1 (en) | 1997-10-06 | 2006-10-03 | Trustees Of Tufts College | Self-encoding fiber optic sensor |
US6607829B1 (en) | 1997-11-13 | 2003-08-19 | Massachusetts Institute Of Technology | Tellurium-containing nanocrystalline materials |
US6207392B1 (en) | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
US6210910B1 (en) | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
GB9811483D0 (en) * | 1998-05-29 | 1998-07-29 | Photonic Research Systems Limi | Luminescence assay using cyclical excitation wavelength sequence |
GB9811480D0 (en) * | 1998-05-29 | 1998-07-29 | Photonic Research Systems Limi | Evanescent-wave excitation of upconverting labels |
US6342397B1 (en) | 1998-06-04 | 2002-01-29 | Erkki Soini | Homogeneous biospecific assay using a solid phase, two-photon excitation and confocal fluorescence detection |
US7060431B2 (en) | 1998-06-24 | 2006-06-13 | Illumina, Inc. | Method of making and decoding of array sensors with microspheres |
DE19940750A1 (de) * | 1998-08-28 | 2000-06-21 | Febit Ferrarius Biotech Gmbh | Träger für Analytbestimmungsverfahren und Verfahren zur Herstellung des Trägers |
AU2149300A (en) * | 1998-11-13 | 2000-06-05 | Bangs Laboratories, Inc. | Labeling microparticles capable of absorbing infrared light and methods of making and using the same |
US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
US7612020B2 (en) | 1998-12-28 | 2009-11-03 | Illumina, Inc. | Composite arrays utilizing microspheres with a hybridization chamber |
US6846460B1 (en) | 1999-01-29 | 2005-01-25 | Illumina, Inc. | Apparatus and method for separation of liquid phases of different density and for fluorous phase organic syntheses |
GB9906929D0 (en) * | 1999-03-26 | 1999-05-19 | Univ Glasgow | Assay system |
US6355431B1 (en) | 1999-04-20 | 2002-03-12 | Illumina, Inc. | Detection of nucleic acid amplification reactions using bead arrays |
US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
EP1190100B1 (en) | 1999-05-20 | 2012-07-25 | Illumina, Inc. | Combinatorial decoding of random nucleic acid arrays |
US8481268B2 (en) | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
US8080380B2 (en) | 1999-05-21 | 2011-12-20 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
CA2382157C (en) | 1999-08-18 | 2012-04-03 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
CA2382436C (en) | 1999-08-30 | 2011-05-17 | Illumina, Inc. | Methods for improving signal detection from an array |
US7332344B2 (en) | 1999-12-01 | 2008-02-19 | Photonic Research Systems Limited | Luminescence assays |
US6235483B1 (en) | 2000-01-31 | 2001-05-22 | Agilent Technologies, Inc. | Methods and kits for indirect labeling of nucleic acids |
US6913884B2 (en) | 2001-08-16 | 2005-07-05 | Illumina, Inc. | Compositions and methods for repetitive use of genomic DNA |
US8076063B2 (en) | 2000-02-07 | 2011-12-13 | Illumina, Inc. | Multiplexed methylation detection methods |
US7361488B2 (en) | 2000-02-07 | 2008-04-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
ATE492652T1 (de) | 2000-02-07 | 2011-01-15 | Illumina Inc | Nukleinsäuredetektionsverfahren mit universellem priming |
US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
CA2401962A1 (en) | 2000-02-07 | 2001-08-09 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
CA2398029A1 (en) * | 2000-02-08 | 2001-08-16 | Cornell Research Foundation, Inc. | Multiphoton excitation through optical fibers for fluorescence spectroscopy |
US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
WO2001061043A2 (en) | 2000-02-16 | 2001-08-23 | Illumina, Inc. | Parallel genotyping of multiple patient samples |
US7057704B2 (en) | 2000-09-17 | 2006-06-06 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US20030045005A1 (en) | 2000-10-17 | 2003-03-06 | Michael Seul | Light-controlled electrokinetic assembly of particles near surfaces |
AU2002243754A1 (en) * | 2001-02-02 | 2002-08-19 | Dana-Farber Cancer Institute, Inc | Rare event detection system |
DE10123439A1 (de) * | 2001-05-14 | 2002-11-21 | Bernhard Trier | Fluoreszenzmikroskop |
US7336988B2 (en) | 2001-08-08 | 2008-02-26 | Lucent Technologies Inc. | Multi-photon endoscopy |
US6885440B2 (en) * | 2001-11-07 | 2005-04-26 | S31, Llc | System and method for detecting and classifying biological particles |
US6643071B2 (en) | 2001-12-21 | 2003-11-04 | Lucent Technologies Inc. | Graded-index lens microscopes |
US6750266B2 (en) | 2001-12-28 | 2004-06-15 | 3M Innovative Properties Company | Multiphoton photosensitization system |
DE10200499A1 (de) * | 2002-01-03 | 2003-07-10 | Zeiss Carl Jena Gmbh | Verfahren und/oder Anordnung zur Identifikation von fluoreszierenden, lumineszierenden und/oder absorbierenden Substanzen auf und/oder in Probenträgern |
US7499806B2 (en) | 2002-02-14 | 2009-03-03 | Illumina, Inc. | Image processing in microsphere arrays |
JP4526004B2 (ja) * | 2002-03-05 | 2010-08-18 | 大日本印刷株式会社 | 希土類元素含有微粒子およびそれを用いた蛍光プローブ |
CN1157462C (zh) | 2002-04-15 | 2004-07-14 | 清华大学 | 一种制备纳米级氟化物基质上转换荧光材料的方法 |
AU2003276852A1 (en) * | 2002-08-16 | 2004-03-03 | Clinical Microarrays, Inc. | Reading of fluorescent arrays |
DE10245432A1 (de) | 2002-09-27 | 2004-04-08 | Micronas Gmbh | Verfahren und Vorrichtung zum Detektieren mindestens eines Lumineszenz-Stoffs |
DE10245435B4 (de) | 2002-09-27 | 2006-03-16 | Micronas Gmbh | Vorrichtung zur Detektion mindestens eines in einer zu untersuchenden Probe enthaltenen Liganden |
US7091500B2 (en) | 2003-06-20 | 2006-08-15 | Lucent Technologies Inc. | Multi-photon endoscopic imaging system |
US7323696B2 (en) | 2004-01-09 | 2008-01-29 | Applera Corporation | Phosphor particle coded beads |
KR20070003879A (ko) * | 2004-01-26 | 2007-01-05 | 안티캔서, 인코포레이티드 | 휴대용 관찰 시스템을 사용한 전신 이미징 |
CN1280623C (zh) | 2004-07-16 | 2006-10-18 | 北京博奥生物芯片有限责任公司 | 一种用于荧光仪器校准测量的校准基片及其制备方法 |
JP4653983B2 (ja) * | 2004-08-23 | 2011-03-16 | 菊治 山下 | 遠赤外線を放射する癌治療器具 |
JP2007071729A (ja) * | 2005-09-07 | 2007-03-22 | Nippon Sheet Glass Co Ltd | 検出方法及び当該検出方法を用いたマイクロ化学システム |
JP2006234794A (ja) * | 2005-01-27 | 2006-09-07 | Nippon Sheet Glass Co Ltd | 信号検出方法、熱レンズ分光分析システム、蛍光検出システム、信号検出装置、信号検出システム、信号検出プログラム、及び記憶媒体 |
EP1845367A1 (en) * | 2005-01-27 | 2007-10-17 | Nippon Sheet Glass Company, Limited | Detection method, micro-chemical system using the detection method, signal detection method, thermal lens spectrophotometry system, fluorescent detection system, signal detection device, signal detection system, signal detection program, and storage medium |
GB2424946A (en) * | 2005-04-05 | 2006-10-11 | Stratec Biomedical Systems Ag | A detection system for substance binding using up-converting fluorescent probes |
US20060246576A1 (en) | 2005-04-06 | 2006-11-02 | Affymetrix, Inc. | Fluidic system and method for processing biological microarrays in personal instrumentation |
FR2884920B1 (fr) * | 2005-04-21 | 2007-08-10 | Horiba Abx Sa Sa | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
AU2006244617B2 (en) | 2005-05-09 | 2013-04-18 | Labrador Diagnostics Llc | Point-of-care fluidic systems and uses thereof |
JP5112312B2 (ja) * | 2005-07-15 | 2013-01-09 | バイオヴィジラント システムズ インコーポレイテッド | 病原体及び微粒子検出システム並びに検出法 |
US20070160175A1 (en) * | 2005-09-23 | 2007-07-12 | Lang Matthew J | Systems and methods for force-fluorescence microscopy |
EP1801593A1 (en) * | 2005-12-22 | 2007-06-27 | Koninklijke Philips Electronics N.V. | A method of imaging biological specimens using inorganic nanoparticles as label agents |
EP2460868A3 (en) * | 2006-01-06 | 2013-06-19 | National University of Singapore | Method of preparing nano-structured material(s) and uses thereof |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
US8012744B2 (en) | 2006-10-13 | 2011-09-06 | Theranos, Inc. | Reducing optical interference in a fluidic device |
US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
WO2008066054A1 (fr) * | 2006-11-28 | 2008-06-05 | Nippon Sheet Glass Company, Limited | Système de détection et sa sonde |
DE102006056949B4 (de) * | 2006-11-30 | 2011-12-22 | Ruprecht-Karls-Universität Heidelberg | Verfahren und Vorrichtung zur Detektion mindestens einer Eigenschaft von mindestens einem Objekt mit einem Mikrochip |
US8110816B2 (en) | 2007-02-28 | 2012-02-07 | Nippon Sheet Glass Company, Limited | Fluorescence detection system |
WO2008110974A1 (en) * | 2007-03-13 | 2008-09-18 | Koninklijke Philips Electronics N. V. | Analyzing biological cell material based on different interactions between illumination light and cell components |
US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
CN103323610B (zh) | 2007-10-02 | 2016-12-28 | 赛拉诺斯股份有限公司 | 模块化现场护理装置及其应用 |
NZ624935A (en) | 2009-10-19 | 2016-01-29 | Theranos Inc | Integrated health data capture and analysis system |
DE102010019095B4 (de) * | 2010-04-30 | 2016-12-08 | Deutsches Zentrum für Luft- und Raumfahrt e.V. | Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung |
US20120309636A1 (en) | 2011-01-21 | 2012-12-06 | Ian Gibbons | Systems and methods for sample use maximization |
JP5487150B2 (ja) * | 2011-03-31 | 2014-05-07 | 富士フイルム株式会社 | 光学的測定方法および光学的測定装置 |
US9588113B2 (en) | 2012-02-22 | 2017-03-07 | Church & Dwight Co., Inc. | Methods for electronic analyte assaying |
SG193046A1 (en) * | 2012-02-23 | 2013-09-30 | Histoindex Pte Ltd | A digital imaging system for biopsy inspection |
DE102012007862A1 (de) * | 2012-04-18 | 2013-10-24 | Heribert Broicher | Vorrichtung zur Identifizierung und Qualitätskontrolle von Material |
KR101364649B1 (ko) | 2012-04-27 | 2014-02-20 | 한국과학기술연구원 | 코어/쉘 구조의 다기능성 자성 나노형광체 및 그 제조방법 |
WO2015026663A1 (en) | 2013-08-19 | 2015-02-26 | University Of Houston | Phosphorescent reporters |
CA2943254C (en) * | 2014-03-24 | 2021-05-04 | Instrumentation Laboratory Company | Bioassay system and method for detecting analytes in body fluids |
US10379046B2 (en) * | 2015-04-08 | 2019-08-13 | Molecular Devices, Llc | Method and system for multiplexed time-resolved fluorescence detection |
DE102015117939A1 (de) * | 2015-10-21 | 2017-04-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Bestimmung einer Strahlendosis und Produkt |
EP3450962A4 (en) * | 2016-04-28 | 2019-11-20 | National University Corporation Nagoya University | FLUORESCENZENONDE FOR FLOW CYTOMETRY AND METHOD FOR SCREENING FLUORESCENCE MARKED CELLS |
JP6633978B2 (ja) * | 2016-06-17 | 2020-01-22 | 積水化学工業株式会社 | 検査キット及び検査方法 |
DE102017105159B4 (de) | 2017-03-10 | 2020-09-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Validierung einer Bestrahlungsanlage |
US20180364150A1 (en) * | 2017-06-14 | 2018-12-20 | Cypress Semiconductor Corporation | Optical monitoring of target characteristics |
RU195925U1 (ru) * | 2019-11-19 | 2020-02-11 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Рязанский государственный радиотехнический университет имени В.Ф. Уткина" | Сканирующий зонд атомно-силового микроскопа с отделяемым телеуправляемым нанокомпозитным излучающим элементом, легированным квантовыми точками, апконвертирующими и магнитными наночастицами структуры ядро-оболочка |
CN113637048B (zh) * | 2020-04-27 | 2023-07-25 | 中国科学院理化技术研究所 | 一种γ-谷氨酰转肽酶的双光子荧光探针及其制备方法和应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US634278A (en) | 1899-06-03 | 1899-10-03 | Leon Stilmant | Speed-changing gear for cycles. |
US4100416A (en) * | 1977-03-02 | 1978-07-11 | Block Engineering, Inc. | Serum fluorescence suppression |
US4172227A (en) | 1978-07-21 | 1979-10-23 | Becton, Dickinson And Company | Flow microfluorometer |
US4347935A (en) | 1979-05-16 | 1982-09-07 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for electrostatically sorting biological cells |
US4667830A (en) | 1981-06-15 | 1987-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | Method and means for sorting individual particles into containers for culturing, cloning, analysis, or the like |
US4724217A (en) * | 1983-10-31 | 1988-02-09 | The United States Of America As Represented By The United States Department Of Energy | Ultratrace analysis of transuranic actinides by laser-induced fluorescence |
US4661913A (en) | 1984-09-11 | 1987-04-28 | Becton, Dickinson And Company | Apparatus and method for the detection and classification of articles using flow cytometry techniques |
US5093234A (en) | 1984-12-24 | 1992-03-03 | Caribbean Microparticles Corporation | Method of aligning, compensating, and calibrating a flow cytometer for analysis of samples, and microbead standards kit therefor |
EP0232357B1 (en) * | 1985-08-05 | 1991-01-30 | Rijksuniversiteit Leiden | Labelled macromolecules; a process for their preparation and their use for immunological or immunocytochemical assays |
DE3541033A1 (de) | 1985-11-19 | 1987-05-21 | Boehringer Mannheim Gmbh | Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz |
US5132242A (en) * | 1987-07-15 | 1992-07-21 | Cheung Sau W | Fluorescent microspheres and methods of using them |
EP0476556A3 (en) * | 1990-09-18 | 1992-11-19 | Takeda Chemical Industries, Ltd. | Method for determination of a light sensitive substance |
US5144224A (en) | 1991-04-01 | 1992-09-01 | Larsen Lawrence E | Millimeter wave flow cytometer |
-
1993
- 1993-09-14 DE DE69333502T patent/DE69333502T2/de not_active Expired - Lifetime
- 1993-09-14 ES ES96200682T patent/ES2216034T3/es not_active Expired - Lifetime
- 1993-09-14 AT AT96200682T patent/ATE266195T1/de not_active IP Right Cessation
- 1993-09-14 DK DK93921595T patent/DK0660936T3/da active
- 1993-09-14 DE DE69334326T patent/DE69334326D1/de not_active Expired - Lifetime
- 1993-09-14 JP JP50828294A patent/JP3420765B2/ja not_active Expired - Lifetime
- 1993-09-14 AT AT93921595T patent/ATE170004T1/de not_active IP Right Cessation
- 1993-09-14 DK DK96200682T patent/DK0723146T3/da active
- 1993-09-14 EP EP03010101A patent/EP1333274B1/en not_active Expired - Lifetime
- 1993-09-14 ES ES93921595T patent/ES2123063T3/es not_active Expired - Lifetime
- 1993-09-14 AT AT03010101T patent/ATE463744T1/de not_active IP Right Cessation
- 1993-09-14 DE DE69320484T patent/DE69320484T2/de not_active Expired - Lifetime
- 1993-09-14 EP EP96200682A patent/EP0723146B1/en not_active Expired - Lifetime
- 1993-09-14 CA CA2144527A patent/CA2144527C/en not_active Expired - Lifetime
- 1993-09-14 WO PCT/US1993/008712 patent/WO1994007142A1/en active IP Right Grant
- 1993-09-14 EP EP93921595A patent/EP0660936B1/en not_active Expired - Lifetime
-
2002
- 2002-10-22 JP JP2002306847A patent/JP3636705B2/ja not_active Expired - Lifetime
-
2004
- 2004-09-24 JP JP2004278564A patent/JP2005104980A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2005104980A (ja) | 2005-04-21 |
DE69334326D1 (de) | 2010-05-20 |
EP1333274B1 (en) | 2010-04-07 |
JPH08501632A (ja) | 1996-02-20 |
EP0723146A1 (en) | 1996-07-24 |
JP2003177096A (ja) | 2003-06-27 |
EP0660936A1 (en) | 1995-07-05 |
WO1994007142A1 (en) | 1994-03-31 |
DE69320484D1 (de) | 1998-09-24 |
DE69333502D1 (de) | 2004-06-09 |
JP3636705B2 (ja) | 2005-04-06 |
ES2216034T3 (es) | 2004-10-16 |
CA2144527A1 (en) | 1994-03-31 |
EP0723146B1 (en) | 2004-05-06 |
JP3420765B2 (ja) | 2003-06-30 |
EP0660936B1 (en) | 1998-08-19 |
EP1333274A3 (en) | 2003-10-22 |
DE69333502T2 (de) | 2005-04-14 |
EP1333274A2 (en) | 2003-08-06 |
ATE170004T1 (de) | 1998-09-15 |
ATE266195T1 (de) | 2004-05-15 |
ATE463744T1 (de) | 2010-04-15 |
CA2144527C (en) | 2010-08-17 |
DK0660936T3 (da) | 1999-05-25 |
ES2123063T3 (es) | 1999-01-01 |
DE69320484T2 (de) | 1998-12-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0723146T3 (da) | Opkonverterende reportermolekyler til biologiske og andre assays ved anvendelse af laser-excitationsteknikker | |
DE69802412D1 (de) | Analytische Testvorrichtung und Verfahren zu ihren Verwendung | |
DK0834074T4 (da) | Detektering af transmembranpotentialer ved optiske metoder | |
ATE227025T1 (de) | Analytische testvorrichtung und verfahren zu ihrer verwendung | |
DE68928994D1 (de) | Elektrochemilumineszente testverfahren | |
SE0000538D0 (sv) | Methods and kits for proximity probing | |
AU637017B2 (en) | Merocyanine and nitro or nitroso substituted polyhalogenated phenolsulfonephthaleins as protein indicators in biological samples | |
ATE317122T1 (de) | Fluoreszierende polarisation | |
FI103434B1 (fi) | Monileimamittauslaite | |
DK590885A (da) | Polynucleotidhybridiseringsproever ved anvendelse af katalyseret luminescens | |
ATE496294T1 (de) | Analyseset mit stechhilfe und messgerät | |
ATE142622T1 (de) | Elektrochemilumineszente rhenium-fraktionen und verfahren | |
BR9300639A (pt) | Particulas marcadoras para uso no ensaio de uma amostra de um fluido biologico,processo pra ensaiar uma amostra de fluido biologico,e,processo para ensaiar uma amostra de sangue | |
ATE543093T1 (de) | Analysegerät für ein grossflächiges bild | |
Ruitenberg et al. | Direct measurement of microplates and its application to enzyme-linked immunosorbent assay | |
DE69430500D1 (de) | Chemilumineszierende Derivate mit langer Emissionswellenlänge und ihre Verwendung in Assays | |
ATE520034T1 (de) | Quantitative analyse einer biologischen probe unbekannter menge | |
Gutmann et al. | UV fluorescence detection and spectroscopy in chemistry and life sciences | |
Almehmadi et al. | Stand‐off Raman spectroscopy is a promising approach for the detection and identification of bloodstains for forensic purposes | |
ATE274702T1 (de) | Verwendung derivatisierter reagenzien in chemilumineszenz- und elektrochemilumineszenz- nachweisverfahren | |
ATE266856T1 (de) | Lichterzeugung, lichtmessung und bestimmung der menge von substanzen in vertiefungen von mikroplatten | |
SU1272198A1 (ru) | Способ количественной электронной оже-спектроскопии дл анализа состава зернограничных,межфазных и поверхностных сегрегаций | |
Thompson et al. | Standardization of Fluorophores Using Phase Fluorometry | |
WO2005058865A3 (en) | Assay for entactogens |