ATE317122T1 - Fluoreszierende polarisation - Google Patents

Fluoreszierende polarisation

Info

Publication number
ATE317122T1
ATE317122T1 AT98941732T AT98941732T ATE317122T1 AT E317122 T1 ATE317122 T1 AT E317122T1 AT 98941732 T AT98941732 T AT 98941732T AT 98941732 T AT98941732 T AT 98941732T AT E317122 T1 ATE317122 T1 AT E317122T1
Authority
AT
Austria
Prior art keywords
assay
fluorescent
protein
fluorescence polarization
labeled protein
Prior art date
Application number
AT98941732T
Other languages
English (en)
Inventor
Hiroshi Nakayama
Jinsei Miyazaki
Original Assignee
Matsushita Electric Industrial Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matsushita Electric Industrial Co Ltd filed Critical Matsushita Electric Industrial Co Ltd
Application granted granted Critical
Publication of ATE317122T1 publication Critical patent/ATE317122T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Vessels And Coating Films For Discharge Lamps (AREA)
  • Luminescent Compositions (AREA)
AT98941732T 1997-09-05 1998-09-04 Fluoreszierende polarisation ATE317122T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24067297 1997-09-05

Publications (1)

Publication Number Publication Date
ATE317122T1 true ATE317122T1 (de) 2006-02-15

Family

ID=17062994

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98941732T ATE317122T1 (de) 1997-09-05 1998-09-04 Fluoreszierende polarisation

Country Status (9)

Country Link
US (2) US6432632B2 (de)
EP (1) EP0957365B1 (de)
JP (1) JP3255293B2 (de)
KR (1) KR20000068915A (de)
CN (1) CN1157602C (de)
AT (1) ATE317122T1 (de)
CA (1) CA2270233A1 (de)
DE (1) DE69833378T2 (de)
WO (1) WO1999013332A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4197797B2 (ja) * 1999-04-28 2008-12-17 新日本製鐵株式会社 クリプトスポリジウムのオーシスト濃度の検査方法
NO20006130D0 (no) * 2000-12-01 2000-12-01 Erling Sundrehagen Reagens og analysemetode
ES2292787T3 (es) * 2001-07-13 2008-03-16 Diachemix Llc Ensayo homogeneo basado en la polimerizacion de fluorescencia para las aflatoxinas.
CN1522367A (zh) * 2002-03-27 2004-08-18 ���µ�����ҵ��ʽ���� 荧光偏振法、其中使用的试剂盒以及生物传感器
AU2003264497A1 (en) * 2002-09-19 2004-04-08 Hamamatsu Photonics K.K. Fluorescence analysis method with the use of fluorescent antibody
JP3898680B2 (ja) * 2003-02-21 2007-03-28 栄次 松浦 酸化ｌｄｌ−ｃｒｐ複合体の測定方法及び測定キット
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
WO2005054854A1 (en) * 2003-11-05 2005-06-16 The United States Of America As Represented By The Secretary Of The Navy Naval Medical Research Center Fluorescence polarization instruments and methods for detection of exposure to biological materials by fluorescence polarization immunoassay of saliva, oral or bodily fluids
US7408640B2 (en) * 2003-11-05 2008-08-05 The United States Of America As Represented By The Secretary Of The Navy Fluorescence polarization instruments and methods for detection of exposure to biological materials by fluorescence polarization immunoassay of saliva, oral or bodily fluids
CA2559723C (en) * 2004-03-18 2010-02-23 Transtech Pharma, Inc. Fluorescence polarization assay related applications
KR100822810B1 (ko) * 2004-11-25 2008-04-18 한국과학기술연구원 랩온어칩에서의 형광 편광 측정 방법 및 장치
KR100859506B1 (ko) * 2005-07-22 2008-09-22 한국과학기술연구원 프롤린 수산화반응에 의한 ｈｉｆ―1 펩타이드와 ｖｂｃ단백질과의 상호작용을 형광편광도를 이용하여 정량적으로분석하는 방법
EP2208985A1 (de) * 2005-08-11 2010-07-21 SRU Biosystems Inc. Markerfreie Bindungsdetektion und Fluoreszenz-Verstärkung kombinierende Analysemethode
US7790406B2 (en) * 2005-08-11 2010-09-07 Sru Biosystems, Inc Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor
ATE456798T1 (de) 2005-10-12 2010-02-15 Allergan Inc Tests der molekularen oder subzellulären interaktivität unter verwendung von depolarisierung nach resonanzenergietransfer (daret)
US20080188007A1 (en) * 2007-02-06 2008-08-07 Meridian Life Science, Inc. Fluorescent single chain antibody and its use in detection of analytes
US20080225265A1 (en) * 2007-03-17 2008-09-18 Mi Research, Inc. Method and apparatus for finding macromolecule crystallization conditions
JP2008233010A (ja) * 2007-03-23 2008-10-02 Sysmex Corp マイクロチャンバアレイを用いた蛍光偏光解消法による標的物質測定方法
US9006283B2 (en) 2007-07-12 2015-04-14 Acumen Pharmaceuticals, Inc. Methods of modifying amyloid β oligomers using non-peptidic compounds
US20110098309A1 (en) * 2007-07-12 2011-04-28 Acumen Pharmaceuticals, Inc. Methods of inhibiting the formation of amyloid-beta diffusable ligands using acylhydrazide compounds
US8962677B2 (en) * 2007-07-12 2015-02-24 Acumen Pharmaceuticals, Inc. Methods of restoring cognitive ability using non-peptidic compounds
CA2707309A1 (en) 2007-12-18 2009-06-25 Acumen Pharmaceuticals, Inc. Novel addl receptor polypeptides, polynucleotides and host cells for recombinant production
CN102175846A (zh) * 2010-12-24 2011-09-07 江南大学 一种双酚a的荧光偏振免疫分析检测方法
US20140161729A1 (en) * 2011-04-07 2014-06-12 Cornell University Cofluorons and methods of making and using them
WO2013058825A1 (en) 2011-04-07 2013-04-25 Cornell University Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same
WO2013058824A1 (en) 2011-04-07 2013-04-25 Cornell University Monomers capable of dimerizing in an aqueous solution, and methods of using same
CN103076456B (zh) * 2012-12-26 2015-02-04 潍坊三维生物工程集团有限公司 一种用免疫透射比浊法检测α1-酸性糖蛋白的试剂盒
EP2944958A1 (de) 2014-04-04 2015-11-18 Techno-Path (Distribution) Verfahren zur Vorhersage von phänotypischer Instabilität in einer Zelle
EP3795999A1 (de) 2014-07-15 2021-03-24 Valitacell Limited Verfahren zur bestimmung der menge eines zielmoleküls in einer probe
JPWO2016072115A1 (ja) * 2014-11-06 2017-08-03 Ｎｅｃソリューションイノベータ株式会社 菌検出方法
EP3075844A1 (de) 2015-04-01 2016-10-05 Valitacell Limited Verfahren zur bestimmung einer zusammengesetzten oder funktionellen eigenschaft eines zellkulturmediums
CN104946249B (zh) * 2015-07-10 2017-05-10 太原理工大学 一种用于胰蛋白酶检测的荧光探针及其制备方法
CN107121416A (zh) * 2017-04-18 2017-09-01 上海理工大学 一种用于免疫活性肽免疫活性检测的荧光偏振分析方法
WO2019212946A1 (en) 2018-04-30 2019-11-07 Ribon Therapeutics Inc. Screening methods for parp modulators
EA202092590A1 (ru) 2018-04-30 2021-04-08 Рибон Терапьютикс Инк. Пиридазиноны в качестве ингибиторов parp7
WO2020223229A1 (en) 2019-04-29 2020-11-05 Ribon Therapeutics, Inc. Solid forms of a parp7 inhibitor
KR20220109401A (ko) 2019-10-30 2022-08-04 리본 테라퓨틱스 인코포레이티드 Parp7 억제제로서의 피리다진온
JP7561364B2 (ja) * 2020-04-30 2024-10-04 国立大学法人東北大学 蛍光偏光免疫分析法
JP7755932B2 (ja) 2021-01-08 2025-10-17 Ｔｉａｎｍａ Ｊａｐａｎ株式会社 蛍光偏光免疫分析用支持体、蛍光偏光免疫分析用キットおよび蛍光偏光免疫分析法
CN118745188A (zh) * 2024-06-24 2024-10-08 中南大学 一种用于检测或筛选parp1抑制剂的荧光探针及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5282722A (en) * 1975-12-26 1977-07-11 Kotai Kasei Kk Immunologically measuring method and apparatus
IL67289A (en) 1982-03-18 1985-12-31 Miles Lab Homogeneous immunoassay with labeled monoclonal anti-analyte
US4629783A (en) * 1985-04-29 1986-12-16 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease
US5869237A (en) * 1988-11-15 1999-02-09 Yale University Amplification karyotyping
US5094819A (en) * 1989-06-16 1992-03-10 Washington Research Foundation Fluorescence-based optical sensor and method for detection of lipid-soluble analytes
JPH03103765A (ja) * 1989-09-18 1991-04-30 Toyobo Co Ltd 固定化抗体または抗原を用いる蛍光偏光免疫測定法
JP2893772B2 (ja) * 1989-12-19 1999-05-24 三菱化学株式会社 免疫測定法
US5230998A (en) * 1991-07-25 1993-07-27 Neurath Alexander R Method for the prescreening of drugs targeted to the V3 hypervariable loop of the HIV-1 envelope glycoprotein gp 120
WO1995006119A1 (en) * 1993-08-24 1995-03-02 Scotgen Limited Recombinant humanized anti-human immunodeficiency virus antibody
US5660991A (en) * 1994-10-28 1997-08-26 Lakowicz; Joseph R. Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical research
WO1997039326A2 (en) 1996-04-18 1997-10-23 Ariad Pharmaceuticals, Inc. In vitro fluorescence polarization assay

Also Published As

Publication number Publication date
CN1157602C (zh) 2004-07-14
DE69833378D1 (de) 2006-04-13
WO1999013332A1 (en) 1999-03-18
CN1237242A (zh) 1999-12-01
CA2270233A1 (en) 1999-03-18
US20020150890A1 (en) 2002-10-17
EP0957365B1 (de) 2006-02-01
KR20000068915A (ko) 2000-11-25
US6432632B2 (en) 2002-08-13
US20010051331A1 (en) 2001-12-13
EP0957365A1 (de) 1999-11-17
JP3255293B2 (ja) 2002-02-12
EP0957365A4 (de) 2000-08-23
DE69833378T2 (de) 2006-10-26

Similar Documents

Publication Publication Date Title
ATE317122T1 (de) Fluoreszierende polarisation
ATE304706T1 (de) System zur messung des elektrischen potentials durch eine membrane
DE69700902D1 (de) Verfahren zur erkennung von ligandenpaar bindung mit erhöter empfindlichkeit
EP0969279A3 (de) Fluoreszenzpolarisationsverfahren bei mehreren Wellenlängen
ATE412050T1 (de) Fluoreszenzprotein-sensoren zur erkennung von analyten
ATE432947T1 (de) Menschliche antikörper als detektionsreagenzien
DK0943097T3 (da) Fremgangsmåde til at påvise IgE
AU6834700A (en) Device and method for determining multiple analytes
WO2002044720A3 (en) Membrane molecule indicator compositions and methods
DE602004024236D1 (en) Assay
DE69029016D1 (de) Heterogene Immuntests
DE50115064D1 (de) Sensor zur lumineszenz-optischen bestimmung eines analyten
AU3659002A (en) Methods, circuits and compositions of matter for in vivo detection of biomolecule concentrations using fluorescent tags
WO2002035228A3 (de) Verfahren und testkit zum nachweis von analyten in einer probe
WO2003106649A3 (en) CONJUGATE TEST AND USES THEREOF
HUP9800225A2 (hu) Eljárás és vegyületek analitok meghatározására remanenciaméréssel és ezek alkalmazásai
ATE392621T1 (de) Verfahren zur quantifizierung von glykiertem protein
DE60137078D1 (de) Elementaranalytik von markierten biologisch aktiven substanzen
AU2001225377A1 (en) Lipoprotein assay
Babichenko et al. Diagnostics of organic substances in water by spectral fluorescent signatures(SFS)
DE59910326D1 (de) Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
DK1423708T3 (da) Sammensætninger og fremgangsmåder til bestemmelser af AA4RP
MX9709597A (es) DTECCIaN DE POTENCIALES DE TRANSMEMBRANA MEDIANTE MÉTODOS aPTICOS.
EP1201767A3 (de) Methode zur Analyse doppelsträngiger DNA
WO2002066982A8 (de) Analyse von modifizierungen und demodifizierungen von proteinen mit ubiquintin-verwandten proteinen mittels fret (fluorescence resonance energy transfer)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties