DK0707567T3 - Fremgangsmåde til syntese af azetidinoner - Google Patents

Fremgangsmåde til syntese af azetidinoner

Info

Publication number
DK0707567T3
DK0707567T3 DK94921407T DK94921407T DK0707567T3 DK 0707567 T3 DK0707567 T3 DK 0707567T3 DK 94921407 T DK94921407 T DK 94921407T DK 94921407 T DK94921407 T DK 94921407T DK 0707567 T3 DK0707567 T3 DK 0707567T3
Authority
DK
Denmark
Prior art keywords
substituted
pct
beta
amino
azetidinones
Prior art date
Application number
DK94921407T
Other languages
Danish (da)
English (en)
Inventor
Chou-Hong Tann
Tiruvettipuram K Thiruvengadam
Timothy Mcallister
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22217215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0707567(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0707567T3 publication Critical patent/DK0707567T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
DK94921407T 1993-07-09 1994-07-01 Fremgangsmåde til syntese af azetidinoner DK0707567T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8935793A 1993-07-09 1993-07-09
PCT/US1994/007291 WO1995001961A1 (en) 1993-07-09 1994-07-01 Process for the synthesis of azetidinones

Publications (1)

Publication Number Publication Date
DK0707567T3 true DK0707567T3 (da) 2001-11-26

Family

ID=22217215

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94921407T DK0707567T3 (da) 1993-07-09 1994-07-01 Fremgangsmåde til syntese af azetidinoner

Country Status (21)

Country Link
US (1) US5728827A (de)
EP (1) EP0707567B1 (de)
JP (1) JP2840452B2 (de)
KR (1) KR0176001B1 (de)
CN (1) CN1071745C (de)
AT (1) ATE205475T1 (de)
AU (1) AU681419B2 (de)
CA (1) CA2166784C (de)
CZ (1) CZ7696A3 (de)
DE (1) DE69428280T2 (de)
DK (1) DK0707567T3 (de)
ES (1) ES2160125T3 (de)
FI (1) FI960095A0 (de)
HU (1) HUT73237A (de)
MX (1) MX9405152A (de)
NO (1) NO306294B1 (de)
NZ (1) NZ268798A (de)
PL (1) PL312502A1 (de)
PT (1) PT707567E (de)
SK (1) SK3796A3 (de)
WO (1) WO1995001961A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631365A (en) 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US6207822B1 (en) 1998-12-07 2001-03-27 Schering Corporation Process for the synthesis of azetidinones
WO2000034240A1 (en) * 1998-12-07 2000-06-15 Schering Corporation Process for the synthesis of azetidinones
US6593078B1 (en) 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
CN100509058C (zh) * 2001-01-26 2009-07-08 先灵公司 过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药以及对于血管适应症的治疗
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
NZ527852A (en) * 2001-03-28 2005-03-24 Schering Corp Enantioselective synthesis of azetidinone intermediate compounds
ES2272776T3 (es) * 2001-09-21 2007-05-01 Schering Corporation Tratamiento de xantomas con derivados de azetidinona como inhibidores de la absorcion de esterol.
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030204096A1 (en) * 2002-03-25 2003-10-30 Schering Corporation Enantioselective synthesis of azetidinone intermediate compounds
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
US7135556B2 (en) * 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
MXPA05009501A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
MXPA05009503A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4688819B2 (ja) 2003-12-23 2011-05-25 アストラゼネカ アクチボラグ コレステロール吸収阻害活性を有するジフェニルアゼチジノン誘導体
CN100471835C (zh) * 2003-12-23 2009-03-25 默克公司 抗高胆固醇血症化合物
WO2005069900A2 (en) * 2004-01-16 2005-08-04 Merck & Co., Inc. Npc1l1 (npc3) and methods of identifying ligands thereof
BRPI0510150A (pt) * 2004-05-21 2007-10-02 Sanofi Aventis Deutschland processo para preparação de derivados de 1,4-difenilacetidinonas
DE102004025071B4 (de) * 2004-05-21 2006-12-21 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Diphenylazetidinon-Derivaten
US20060135755A1 (en) * 2004-12-20 2006-06-22 Schering Corporation Process for the synthesis of azetidinones
WO2007001975A1 (en) * 2005-06-20 2007-01-04 Schering Corporation Piperidine derivatives useful as histamine h3 antagonists
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
WO2007100807A2 (en) * 2006-02-24 2007-09-07 Schering Corporation Npc1l1 orthologues
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
MX2009002398A (es) * 2006-09-05 2009-03-16 Schering Corp Combinaciones farmaceuticas para manejo de lipidos y en el tratamiento de aterosclerosis y estatosis hepatica.
WO2008032338A2 (en) * 2006-09-11 2008-03-20 Manne Satyanarayana Reddy Improved process for the preparation of ezetimibe and its intermediates
CN101679236B (zh) 2007-01-24 2013-03-06 克尔克公司 依泽替米贝的制备方法和其的衍生物
WO2010113175A2 (en) 2009-04-01 2010-10-07 Matrix Laboratories Ltd Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
CN104803858B (zh) * 2014-01-23 2019-03-01 东莞东阳光科研发有限公司 一种制备四丁基氟化铵三水合物的方法
JP2023513272A (ja) 2020-02-07 2023-03-30 ガシャーブラム・バイオ・インコーポレイテッド ヘテロ環ｇｌｐ－１アゴニスト

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0333268A1 (de) * 1988-03-18 1989-09-20 Merck & Co. Inc. Verfahren zur Synthese eines chiralen 3-beta-Wasserstoff-(3R) 4-aroyloxyazetidinons
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
US4983597A (en) * 1989-08-31 1991-01-08 Merck & Co., Inc. Beta-lactams as anticholesterolemic agents
US5085473A (en) * 1990-10-09 1992-02-04 Yuhe Yang Air actuated car curtain device
TW223059B (de) * 1991-07-23 1994-05-01 Schering Corp

Also Published As

Publication number Publication date
CA2166784C (en) 2001-12-11
FI960095A (fi) 1996-01-09
NO960083D0 (no) 1996-01-08
ES2160125T3 (es) 2001-11-01
PT707567E (pt) 2002-01-30
EP0707567A1 (de) 1996-04-24
US5728827A (en) 1998-03-17
SK3796A3 (en) 1997-02-05
ATE205475T1 (de) 2001-09-15
JPH08507085A (ja) 1996-07-30
NO960083L (no) 1996-03-04
EP0707567B1 (de) 2001-09-12
AU681419B2 (en) 1997-08-28
DE69428280T2 (de) 2002-06-13
WO1995001961A1 (en) 1995-01-19
NZ268798A (en) 1997-01-29
PL312502A1 (en) 1996-04-29
CN1071745C (zh) 2001-09-26
KR0176001B1 (ko) 1999-03-20
AU7214694A (en) 1995-02-06
MX9405152A (es) 1995-01-31
DE69428280D1 (de) 2001-10-18
CZ7696A3 (en) 1996-04-17
JP2840452B2 (ja) 1998-12-24
CA2166784A1 (en) 1995-01-19
CN1126989A (zh) 1996-07-17
KR960703853A (ko) 1996-08-31
NO306294B1 (no) 1999-10-18
FI960095A0 (fi) 1996-01-09
HU9503748D0 (en) 1996-02-28
HUT73237A (en) 1996-07-29

Similar Documents

Publication Publication Date Title
DK0707567T3 (da) Fremgangsmåde til syntese af azetidinoner
IL113141A0 (en) Intermediates for hypoglycemic hydroxyurea detivatives
PT934325E (pt) Trisanidridos biciclicos de tetrafosfonato
ZA9811576B (en) Anilide derivative, production and use thereof.
DK0703788T3 (da) Stabiliseret phenylalaninammoniaklyase
MXPA04005847A (es) Compuestos derivados de 4-sulfuro/sulfoxido/sulfonil-1h-pirazolilo, para uso en enfermedades asociadas con el receptor 5-ht2c.
DE69433984D1 (de) Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d
IL172973A (en) Process for the preparation of (4s, 5r) - n - boc - 2 - (2' 4 - dimethoxyphenyl) - 4 - isobutyl - 1 - oxazolidine - 5 - carboxylic acid
DK0687260T3 (da) Fremgangsmåde til fremstillingen af 9-desoxotaxaner
ATE207929T1 (de) Diastereomerenreine 3-oxo und 3-thioxo-4-aza- androstanderivate und ihre verwendung als antiandrogene
ID23053A (id) Karboksamida yang digunakan sebagai agonis 5-ht <if>
ZA961364B (en) 1-Aryl-2-acylamino-ethane compounds
HK1088325A1 (en) Process for the preparation of baccatin III derivatives
NZ331875A (en) Asymmetric synthesis of R-alpha-propyl-piperonyl amine and its analogs
BG104243A (en) Method for the synthesis of quinoline derivatives
YU12000A (sh) Supstituisani 1,2,3,4,5,6-heksahidro-2,6-metano-3-benzazocin -10-oli, postupak za njihovo pripremanje i njihova primena kao lekova
MY133666A (en) Enzymatic process for stereoselective preparation of therapeutic amides
CA2044491A1 (fr) Nouveau procede de preparation industrielle du 4-chloro 3-sulfamoyl n-(2,3-dihydro 2-methyl 1h-indol -1-yl) benzamide
MX9701569A (es) Pirimidin(tio)onas substituidas.
MXPA03006057A (es) Proceso para preparar (+) trans-4-p-fluorofenil -3 hidroximetil.
MXPA04004980A (es) Antagonistas del receptor ccr-3.
NZ516209A (en) Indoloazepines as vasopressin receptor antagonists