MXPA03006057A - Proceso para preparar (+) trans-4-p-fluorofenil -3 hidroximetil. - Google Patents

Proceso para preparar (+) trans-4-p-fluorofenil -3 hidroximetil.

Info

Publication number
MXPA03006057A
MXPA03006057A MXPA03006057A MXPA03006057A MXPA03006057A MX PA03006057 A MXPA03006057 A MX PA03006057A MX PA03006057 A MXPA03006057 A MX PA03006057A MX PA03006057 A MXPA03006057 A MX PA03006057A MX PA03006057 A MXPA03006057 A MX PA03006057A
Authority
MX
Mexico
Prior art keywords
preparing
fluorophenyl
trans
plusmn
methylpiperidine
Prior art date
Application number
MXPA03006057A
Other languages
English (en)
Inventor
Foguet Rafael
Original Assignee
Ferrer Intertacional S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Intertacional S A filed Critical Ferrer Intertacional S A
Publication of MXPA03006057A publication Critical patent/MXPA03006057A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
MXPA03006057A 2001-01-04 2001-01-04 Proceso para preparar (+) trans-4-p-fluorofenil -3 hidroximetil. MXPA03006057A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2001/000049 WO2002053537A1 (en) 2001-01-04 2001-01-04 Process for preparing (±) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine

Publications (1)

Publication Number Publication Date
MXPA03006057A true MXPA03006057A (es) 2004-01-26

Family

ID=8164242

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03006057A MXPA03006057A (es) 2001-01-04 2001-01-04 Proceso para preparar (+) trans-4-p-fluorofenil -3 hidroximetil.

Country Status (17)

Country Link
US (1) US6881845B2 (es)
EP (1) EP1347960B1 (es)
JP (1) JP2004520333A (es)
KR (1) KR20030067742A (es)
AT (1) ATE282594T1 (es)
BR (1) BR0116721A (es)
CA (1) CA2433605A1 (es)
DE (1) DE60107292T2 (es)
DK (1) DK1347960T3 (es)
ES (1) ES2232588T3 (es)
IL (1) IL156768A0 (es)
MX (1) MXPA03006057A (es)
NO (1) NO20033049L (es)
NZ (1) NZ526874A (es)
PT (1) PT1347960E (es)
TW (1) TW593279B (es)
WO (1) WO2002053537A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004509103A (ja) * 2000-09-11 2004-03-25 セプレイコー インコーポレイテッド モノアミン受容体及び輸送体のリガンドならびにその使用方法
DE10240026A1 (de) * 2002-08-27 2004-03-11 Merck Patent Gmbh Verfahren zur Herstellung von Monoalkylaminoketonen
WO2004043921A1 (en) * 2002-11-11 2004-05-27 Natco Pharma Limited Novel process for the preparation of 4-aryl-3-hydroxymethyl-1-methylpiperidines.
WO2005063707A1 (en) * 2003-12-26 2005-07-14 Natco Pharma Limited Enantiospecific process for the preparation of paroxetine intermediate
WO2007089193A1 (en) * 2006-02-02 2007-08-09 Astrazeneca Ab A process for preparing 2-hydroxy-3- [5- (morpholin-4-ylmethyl)pyridin-2-yl] lh-indole-5-carbonitrile as a free base or salts thereof
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
WO2022269643A1 (en) * 2021-06-25 2022-12-29 Vihita Chem Private Limited An improved process for the preparation of intermediate for paroxetine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
DE3680184D1 (de) * 1985-08-10 1991-08-14 Beecham Group Plc Verfahren zur herstellung von arylpiperidincarbinol.
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
CA2220963A1 (en) 1995-05-17 1996-11-21 Novo Nordisk A/S Process for preparing 4-aryl-piperidine derivatives
EP1384711A1 (en) 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Optical resolution of a piperidine derivative
HUP0003958A3 (en) 1997-05-29 2001-06-28 Smithkline Beecham Plc Process for preparation of 4-aryl-piperidines and intermediates
EP1124802A1 (en) 1998-11-02 2001-08-22 Synthon B.V. Process for producing 4-arylpiperidine-3-carbinols and related compounds

Also Published As

Publication number Publication date
JP2004520333A (ja) 2004-07-08
NO20033049L (no) 2003-08-18
US6881845B2 (en) 2005-04-19
US20040215020A1 (en) 2004-10-28
DE60107292T2 (de) 2005-12-01
IL156768A0 (en) 2004-02-08
WO2002053537A8 (en) 2002-08-08
ATE282594T1 (de) 2004-12-15
NO20033049D0 (no) 2003-07-03
EP1347960B1 (en) 2004-11-17
WO2002053537A1 (en) 2002-07-11
KR20030067742A (ko) 2003-08-14
TW593279B (en) 2004-06-21
CA2433605A1 (en) 2002-07-11
PT1347960E (pt) 2005-03-31
DK1347960T3 (da) 2005-03-21
DE60107292D1 (de) 2004-12-23
NZ526874A (en) 2005-07-29
EP1347960A1 (en) 2003-10-01
BR0116721A (pt) 2003-12-23
ES2232588T3 (es) 2005-06-01

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Legal Events

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FA Abandonment or withdrawal