DK0633784T3 - Hepatitisvacciner indeholdende 3-O-diacyleret monophosphoryl-lipid A - Google Patents
Hepatitisvacciner indeholdende 3-O-diacyleret monophosphoryl-lipid AInfo
- Publication number
- DK0633784T3 DK0633784T3 DK93906601.5T DK93906601T DK0633784T3 DK 0633784 T3 DK0633784 T3 DK 0633784T3 DK 93906601 T DK93906601 T DK 93906601T DK 0633784 T3 DK0633784 T3 DK 0633784T3
- Authority
- DK
- Denmark
- Prior art keywords
- diacylated
- monophosphoryl lipid
- vaccines containing
- hepatitis vaccines
- hepatitis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
- C12N2770/32434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929206789A GB9206789D0 (en) | 1992-03-27 | 1992-03-27 | Vaccine |
GB929206788A GB9206788D0 (en) | 1992-03-27 | 1992-03-27 | Vaccine |
GB929206797A GB9206797D0 (en) | 1992-03-27 | 1992-03-27 | Vaccine |
GB929206786A GB9206786D0 (en) | 1992-03-27 | 1992-03-27 | Vaccine |
PCT/EP1993/000712 WO1993019780A1 (en) | 1992-03-27 | 1993-03-24 | Hepatitis vaccines containing 3-o-deacylated monophoshoryl lipid a |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0633784T3 true DK0633784T3 (da) | 1997-01-20 |
DK0633784T4 DK0633784T4 (da) | 2001-12-31 |
Family
ID=27450853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93906601T DK0633784T4 (da) | 1992-03-27 | 1993-03-24 | Hepatitisvacciner indeholdende 3-O-deacyleret monophosphoryl-lipid A |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0633784B2 (da) |
JP (1) | JP3470719B2 (da) |
KR (1) | KR100270134B1 (da) |
CN (1) | CN1072963C (da) |
AP (1) | AP570A (da) |
AT (1) | ATE146678T1 (da) |
AU (4) | AU3751693A (da) |
CA (1) | CA2132833C (da) |
CZ (1) | CZ283424B6 (da) |
DE (1) | DE69306940T3 (da) |
DK (1) | DK0633784T4 (da) |
ES (1) | ES2098029T5 (da) |
FI (1) | FI110843B (da) |
GR (1) | GR3022174T3 (da) |
HK (1) | HK1003218A1 (da) |
HU (1) | HU221253B1 (da) |
IL (1) | IL105161A (da) |
MA (1) | MA22842A1 (da) |
MY (1) | MY111880A (da) |
NO (1) | NO309458B1 (da) |
NZ (1) | NZ249868A (da) |
RU (1) | RU2121849C1 (da) |
SA (1) | SA93130573B1 (da) |
SG (1) | SG48375A1 (da) |
SI (1) | SI9300149B (da) |
SK (1) | SK280160B6 (da) |
UA (1) | UA44688C2 (da) |
WO (1) | WO1993019780A1 (da) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
ES2162139T5 (es) * | 1993-03-23 | 2008-05-16 | Smithkline Beecham Biologicals S.A. | Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado. |
GB9503863D0 (en) * | 1995-02-25 | 1995-04-19 | Smithkline Beecham Biolog | Vaccine compositions |
US6488934B1 (en) | 1995-02-25 | 2002-12-03 | Smithkline Beecham Biologicals S.A. | Hepatitis B vaccine |
GB9513261D0 (en) * | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
IL137998A0 (en) * | 1998-03-09 | 2001-10-31 | Smithkline Beecham Biolog | Combined vaccine compositions |
US6306404B1 (en) | 1998-07-14 | 2001-10-23 | American Cyanamid Company | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
EP1126876B1 (en) | 1998-10-16 | 2007-03-21 | GlaxoSmithKline Biologicals S.A. | Adjuvant systems and vaccines |
GB9822714D0 (en) * | 1998-10-16 | 1998-12-09 | Smithkline Beecham Sa | Vaccines |
FI108150B (fi) | 1999-02-15 | 2001-11-30 | Sulzer Pumpen Ag | Menetelmä ja laitteisto massan käsittelemiseksi |
US6635261B2 (en) | 1999-07-13 | 2003-10-21 | Wyeth Holdings Corporation | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
GB9921147D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
ES2540770T3 (es) | 2004-09-22 | 2015-07-13 | Glaxosmithkline Biologicals Sa | Composición inmunógena para uso en vacunación contra estafilococos |
TW200722101A (en) | 2005-03-23 | 2007-06-16 | Glaxosmithkline Biolog Sa | Novel composition |
PL2368572T3 (pl) | 2005-11-04 | 2020-11-16 | Seqirus UK Limited | Szczepionki z adjuwantem z niewirionowymi antygenami otrzymane z wirusów grypy hodowanych w hodowli komórkowej |
JP2009514839A (ja) | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | サイトカイン誘導剤を含むアジュバントインフルエンザワクチン |
CA2628328A1 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics S.R.L. | Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
NZ567978A (en) | 2005-11-04 | 2011-09-30 | Novartis Vaccines & Diagnostic | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
PT1962899E (pt) | 2005-12-22 | 2011-10-19 | Glaxosmithkline Biolog Sa | Vacina conjugada polissacarídica pneumocócica |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
EP3753574A1 (en) | 2006-01-27 | 2020-12-23 | Seqirus UK Limited | Influenza vaccines containing hemagglutinin and matrix proteins |
EP2010537B1 (en) | 2006-03-23 | 2011-12-28 | Novartis AG | Imidazoquinoxaline compounds as immunomodulators |
WO2007110776A1 (en) | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
EA020459B1 (ru) | 2006-03-30 | 2014-11-28 | Глаксосмитклайн Байолоджикалс С.А. | Иммуногенная композиция |
US20100015168A1 (en) | 2006-06-09 | 2010-01-21 | Novartis Ag | Immunogenic compositions for streptococcus agalactiae |
MX2009000660A (es) | 2006-07-17 | 2009-04-08 | Glaxosmithkline Biolog Sa | Vacuna de influenza. |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
NZ575271A (en) | 2006-09-11 | 2011-09-30 | Novartis Ag | Making influenza virus vaccines without using eggs |
PL2121011T3 (pl) | 2006-12-06 | 2014-10-31 | Novartis Ag | Szczepionki zawierające antygeny czterech szczepów wirusa grypy |
TW200908994A (en) | 2007-04-20 | 2009-03-01 | Glaxosmithkline Biolog Sa | Vaccine |
BRPI0813644B8 (pt) | 2007-06-26 | 2021-05-25 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, processo para fabricar a mesma, e, uso da composição imunogênica ou vacina |
CN101784283A (zh) | 2007-06-27 | 2010-07-21 | 诺华有限公司 | 低添加流感疫苗 |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
WO2009081172A1 (en) | 2007-12-24 | 2009-07-02 | Novartis Ag | Assays for adsorbed influenza vaccines |
AU2010220824A1 (en) | 2009-03-05 | 2011-10-20 | Jenny Colleen Mccloskey | Treatment of infection |
PL3178490T3 (pl) | 2009-07-15 | 2022-08-01 | Glaxosmithkline Biologicals S.A. | Kompozycje białka f rsv i sposoby ich wytwarzania |
GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
EA025152B1 (ru) | 2010-12-02 | 2016-11-30 | Бионор Иммуно Ас | Конструкция пептидного каркаса |
AU2012204955B2 (en) | 2011-01-06 | 2016-10-06 | Bionor Immuno As | Monomeric and multimeric immunogenic peptides |
EP4144368A1 (en) | 2011-01-26 | 2023-03-08 | GlaxoSmithKline Biologicals S.A. | Rsv immunization regimen |
WO2012158613A1 (en) | 2011-05-13 | 2012-11-22 | Novartis Ag | Pre-fusion rsv f antigens |
KR20150018870A (ko) | 2012-06-06 | 2015-02-24 | 바이오노르 이뮤노 에이에스 | 면역원 및 투여 반응제로서 사용하기 위한 바이러스 단백질로부터 유래하는 펩타이드 |
EP3313439A2 (en) | 2015-06-26 | 2018-05-02 | Seqirus UK Limited | Antigenically matched influenza vaccines |
US20230109142A1 (en) | 2020-02-14 | 2023-04-06 | Immunor As | Corona virus vaccine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE70308T1 (de) * | 1984-09-12 | 1991-12-15 | Chiron Corp | Hybridpartikel-immunogene. |
JPH02500880A (ja) * | 1987-11-18 | 1990-03-29 | カイロン コーポレイション | Nanbvの診断用薬およびワクチン |
AU3748489A (en) * | 1988-06-17 | 1990-01-12 | Genelabs Incorporated | Enterically transmitted non-a/non-b hepatitis viral agent |
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
ATE159031T1 (de) * | 1989-07-25 | 1997-10-15 | Smithkline Biolog | Antigene sowie verfahren zu deren herstellung |
CA2065287C (en) * | 1989-09-15 | 1999-12-21 | Tatsuo Miyamura | New hcv isolates |
IL97985A0 (en) * | 1990-05-07 | 1992-06-21 | North American Vaccine Inc | Improved vaccine compositions |
EP0563091A1 (en) * | 1990-12-20 | 1993-10-06 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccines based on hepatitis b surface antigen |
-
1993
- 1993-03-23 MA MA23137A patent/MA22842A1/fr unknown
- 1993-03-23 MY MYPI93000533A patent/MY111880A/en unknown
- 1993-03-24 EP EP93906601A patent/EP0633784B2/en not_active Expired - Lifetime
- 1993-03-24 CA CA002132833A patent/CA2132833C/en not_active Expired - Lifetime
- 1993-03-24 HU HU9402758A patent/HU221253B1/hu unknown
- 1993-03-24 UA UA94105947A patent/UA44688C2/uk unknown
- 1993-03-24 SG SG1996009183A patent/SG48375A1/en unknown
- 1993-03-24 NZ NZ249868A patent/NZ249868A/en not_active IP Right Cessation
- 1993-03-24 DE DE69306940T patent/DE69306940T3/de not_active Expired - Lifetime
- 1993-03-24 RU RU94042386A patent/RU2121849C1/ru active
- 1993-03-24 AU AU37516/93A patent/AU3751693A/en not_active Abandoned
- 1993-03-24 CZ CZ942355A patent/CZ283424B6/cs not_active IP Right Cessation
- 1993-03-24 WO PCT/EP1993/000712 patent/WO1993019780A1/en active IP Right Grant
- 1993-03-24 KR KR1019940703355A patent/KR100270134B1/ko not_active IP Right Cessation
- 1993-03-24 AT AT93906601T patent/ATE146678T1/de active
- 1993-03-24 JP JP51704693A patent/JP3470719B2/ja not_active Expired - Lifetime
- 1993-03-24 SK SK1152-94A patent/SK280160B6/sk not_active IP Right Cessation
- 1993-03-24 DK DK93906601T patent/DK0633784T4/da active
- 1993-03-24 ES ES93906601T patent/ES2098029T5/es not_active Expired - Lifetime
- 1993-03-25 IL IL10516193A patent/IL105161A/en not_active IP Right Cessation
- 1993-03-25 AP APAP/P/1993/000502A patent/AP570A/en active
- 1993-03-26 CN CN93105232A patent/CN1072963C/zh not_active Expired - Lifetime
- 1993-03-26 SI SI9300149A patent/SI9300149B/sl unknown
- 1993-06-08 SA SA93130573A patent/SA93130573B1/ar unknown
-
1994
- 1994-09-26 NO NO943571A patent/NO309458B1/no not_active IP Right Cessation
- 1994-09-26 FI FI944442A patent/FI110843B/fi not_active IP Right Cessation
-
1996
- 1996-09-05 AU AU64457/96A patent/AU6445796A/en not_active Abandoned
- 1996-12-30 GR GR960403615T patent/GR3022174T3/el unknown
-
1998
- 1998-03-19 HK HK98102341A patent/HK1003218A1/xx unknown
-
1999
- 1999-06-10 AU AU33974/99A patent/AU3397499A/en not_active Abandoned
-
2002
- 2002-01-02 AU AU10008/02A patent/AU767755B2/en not_active Expired
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0633784T3 (da) | Hepatitisvacciner indeholdende 3-O-diacyleret monophosphoryl-lipid A | |
DK0689454T4 (da) | Vaccinepræparater indeholdende 3-O-deacyleret monophosphoryl-lipid A | |
DK0512017T3 (da) | Vacciner | |
NO976060D0 (no) | Vaksiner mot hepatitt C | |
FI945483A0 (fi) | Hepatiitti B - pinta-antigeenejä ja muita antigeenejä sisältäviä yhdistelmärokotteita | |
DK0671948T3 (da) | Vaccinepræparat indeholdende adjuvanser | |
CY2007016I1 (el) | Εμβολιο ιου θηλωματος | |
NO930699D0 (no) | Hoeyeffektiv vaeske/vaeske hydrosyklon | |
NO950483D0 (no) | Vaksine mot hepatitt-A | |
FI944052A (fi) | Oraalinen rokote | |
KR890701743A (ko) | B형 간염 표면 항원 백신 | |
IL79740A0 (en) | Hepatitis vaccine | |
PT85845A (de) | Vaccine gegen hepatitis a | |
IL94510A0 (en) | Influenza vaccine | |
GB9020799D0 (en) | Viral vaccines | |
BR1100917A (pt) | Vacina contra hepatite contendo lipìdio "a"monofosforil 3-0 deacilado | |
ID1028B (id) | Vaksin | |
NO923242D0 (no) | Oral vaksine |