DK0618808T3 - Farmaceutiske præparater der indeholder gonadotropin med saccharosestabilisator - Google Patents
Farmaceutiske præparater der indeholder gonadotropin med saccharosestabilisatorInfo
- Publication number
- DK0618808T3 DK0618808T3 DK93901557T DK93901557T DK0618808T3 DK 0618808 T3 DK0618808 T3 DK 0618808T3 DK 93901557 T DK93901557 T DK 93901557T DK 93901557 T DK93901557 T DK 93901557T DK 0618808 T3 DK0618808 T3 DK 0618808T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- pharmaceuticals containing
- sucrose
- containing gonadotropin
- sec
- Prior art date
Links
- 102000006771 Gonadotropins Human genes 0.000 title abstract 2
- 108010086677 Gonadotropins Proteins 0.000 title abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 title abstract 2
- 229930006000 Sucrose Natural products 0.000 title abstract 2
- 239000002622 gonadotropin Substances 0.000 title abstract 2
- 239000005720 sucrose Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 239000003381 stabilizer Substances 0.000 title 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229940094892 gonadotropins Drugs 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM910952A IT1250075B (it) | 1991-12-18 | 1991-12-18 | Composizioni farmaceutiche contenenti gonadotropine. |
| PCT/IT1992/000165 WO1993011788A1 (en) | 1991-12-18 | 1992-12-17 | Gonadotropin containing pharmaceutical compositions with sucrose stabilizer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0618808T3 true DK0618808T3 (da) | 2000-05-15 |
Family
ID=11400511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93901557T DK0618808T3 (da) | 1991-12-18 | 1992-12-17 | Farmaceutiske præparater der indeholder gonadotropin med saccharosestabilisator |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5650390A (da) |
| EP (1) | EP0618808B1 (da) |
| JP (1) | JP3702313B2 (da) |
| AT (1) | ATE189608T1 (da) |
| AU (1) | AU677773B2 (da) |
| CA (1) | CA2124801C (da) |
| DE (1) | DE69230672T2 (da) |
| DK (1) | DK0618808T3 (da) |
| ES (1) | ES2142860T3 (da) |
| GR (1) | GR3033276T3 (da) |
| IT (1) | IT1250075B (da) |
| PT (1) | PT618808E (da) |
| WO (1) | WO1993011788A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5828979A (en) * | 1994-09-01 | 1998-10-27 | Harris Corporation | Automatic train control system and method |
| KR100377967B1 (ko) * | 1995-03-21 | 2003-06-12 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | Hcg액상조성물 |
| US6319504B1 (en) | 1996-06-24 | 2001-11-20 | University Of Maryland Biotechnology Institute | Treatment and prevention of HIV infection by administration of derivatives of human chorionic gonadotropin |
| IT1284876B1 (it) * | 1996-08-07 | 1998-05-22 | Applied Research Systems | Hcg come inibitore della collagenasi |
| IL122732A0 (en) * | 1997-01-15 | 1998-08-16 | Akzo Nobel Nv | Liquid gonadotropin-containing formulation its preparation and a device containing same |
| JP4719357B2 (ja) * | 1998-07-23 | 2011-07-06 | アレス トレイディング ソシエテ アノニム | Ｆｓｈ及びｆｓｈ変異体の製剤、製品及び方法 |
| US20030166525A1 (en) | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| EP1169053A1 (en) | 1999-04-13 | 2002-01-09 | Inhale Therapeutic Systems, Inc. | Pulmonary administration of dry powder formulations for treating infertility |
| UA78676C2 (en) * | 2000-02-22 | 2007-04-25 | Applied Research Systems | Purified lh |
| CN100482679C (zh) * | 2000-02-22 | 2009-04-29 | 雪兰诺实验室有限公司 | 人绒毛膜促性腺激素的纯化方法 |
| GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| EA009210B1 (ru) * | 2001-09-12 | 2007-12-28 | Апплайд Резеч Системз Арс Холдинг Н.В. | Способ индукции множественного фолликулогенеза |
| EP1471891A4 (en) * | 2002-02-08 | 2007-04-11 | Alkermes Inc | POLYMER-BASED COMPOSITIONS FOR PROLONGED RELEASE |
| WO2004087213A1 (en) | 2003-04-02 | 2004-10-14 | Ares Trading S.A. | Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant |
| PT1638595E (pt) * | 2003-06-20 | 2013-04-26 | Ares Trading Sa | Fsh liofilizada / formulações de hl |
| KR101105871B1 (ko) * | 2005-09-27 | 2012-01-16 | 주식회사 엘지생명과학 | 인 난포자극호르몬의 안정한 용액 제형 |
| MY153976A (en) * | 2007-11-01 | 2015-04-30 | Merck Serono Sa | Lh liquid formulations |
| CN101269215B (zh) * | 2008-05-15 | 2011-03-23 | 上海天伟生物制药有限公司 | 一种糖蛋白激素组合物 |
| CN102309747B (zh) * | 2008-09-17 | 2013-04-17 | 上海天伟生物制药有限公司 | 高纯度绝经期促性腺素冻干针剂 |
| KR101483165B1 (ko) * | 2009-12-22 | 2015-01-15 | 샹하이 테크웰 바이오파마슈티컬 컴퍼니, 리미티드 | 인간폐경성선자극호르몬의 조성물 |
| JP6426410B2 (ja) * | 2013-09-11 | 2018-11-21 | 第一三共株式会社 | 室温保存用凍結乾燥製剤 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3637640A (en) * | 1970-05-04 | 1972-01-25 | Diagnostic Data Inc | Orgotein stabilized with saccharide process and products |
| US3816617A (en) * | 1972-07-25 | 1974-06-11 | American Home Prod | Method for inducing menses |
| DD141996A1 (de) * | 1979-02-21 | 1980-06-04 | Ingrid Wolf | Verfahren zur herstellung von lyophilisierten lhrh-praeparationen |
| JPS59109862A (ja) * | 1982-12-15 | 1984-06-25 | Takeda Chem Ind Ltd | 凍結乾燥感作血球の製造法 |
| ATE169334T1 (de) * | 1983-11-02 | 1998-08-15 | Applied Research Systems | Herstellung heterodimirer menschlicher fruchtbarkeitshormone |
| JPS60258125A (ja) * | 1984-06-06 | 1985-12-20 | Hayashibara Biochem Lab Inc | 蛋白性生理活性物質を含有する水溶性乾燥物 |
| IT1206302B (it) * | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
| US5215743A (en) * | 1988-04-13 | 1993-06-01 | Maninder Singh | Tumor necrosis factor formulations |
| ATE111157T1 (de) * | 1988-04-29 | 1994-09-15 | Genetics Inst | Lagerungsstabile zusammensetzungen von homogenem dimerem m-csf. |
| JPH02121933A (ja) * | 1988-10-28 | 1990-05-09 | Kagaku Shiryo Kenkyusho:Kk | 動物用油性ホルモン顆粒剤 |
| US5087615A (en) * | 1989-03-17 | 1992-02-11 | Applied Research Systems Ars Holding N.V. | Novel method of ovulation induction in humans |
| IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
-
1991
- 1991-12-18 IT ITRM910952A patent/IT1250075B/it active IP Right Grant
-
1992
- 1992-12-17 DK DK93901557T patent/DK0618808T3/da active
- 1992-12-17 WO PCT/IT1992/000165 patent/WO1993011788A1/en active IP Right Grant
- 1992-12-17 DE DE69230672T patent/DE69230672T2/de not_active Expired - Lifetime
- 1992-12-17 AT AT93901557T patent/ATE189608T1/de active
- 1992-12-17 EP EP93901557A patent/EP0618808B1/en not_active Expired - Lifetime
- 1992-12-17 PT PT93901557T patent/PT618808E/pt unknown
- 1992-12-17 US US08/244,575 patent/US5650390A/en not_active Expired - Lifetime
- 1992-12-17 AU AU32662/93A patent/AU677773B2/en not_active Expired
- 1992-12-17 JP JP51077493A patent/JP3702313B2/ja not_active Expired - Lifetime
- 1992-12-17 CA CA002124801A patent/CA2124801C/en not_active Expired - Lifetime
- 1992-12-17 ES ES93901557T patent/ES2142860T3/es not_active Expired - Lifetime
-
2000
- 2000-04-19 GR GR20000400959T patent/GR3033276T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE189608T1 (de) | 2000-02-15 |
| CA2124801C (en) | 2007-08-07 |
| DE69230672T2 (de) | 2000-09-21 |
| GR3033276T3 (en) | 2000-09-29 |
| JPH07507047A (ja) | 1995-08-03 |
| CA2124801A1 (en) | 1993-06-24 |
| WO1993011788A1 (en) | 1993-06-24 |
| EP0618808B1 (en) | 2000-02-09 |
| US5650390A (en) | 1997-07-22 |
| PT618808E (pt) | 2000-07-31 |
| EP0618808A1 (en) | 1994-10-12 |
| ES2142860T3 (es) | 2000-05-01 |
| AU677773B2 (en) | 1997-05-08 |
| ITRM910952A0 (it) | 1991-12-18 |
| AU3266293A (en) | 1993-07-19 |
| JP3702313B2 (ja) | 2005-10-05 |
| DE69230672D1 (de) | 2000-03-16 |
| ITRM910952A1 (it) | 1993-06-18 |
| IT1250075B (it) | 1995-03-30 |
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