ITRM910952A1 - Composizioni farmaceutiche contenenti gonadotropine. - Google Patents

Composizioni farmaceutiche contenenti gonadotropine.

Info

Publication number
ITRM910952A1
ITRM910952A1 IT000952A ITRM910952A ITRM910952A1 IT RM910952 A1 ITRM910952 A1 IT RM910952A1 IT 000952 A IT000952 A IT 000952A IT RM910952 A ITRM910952 A IT RM910952A IT RM910952 A1 ITRM910952 A1 IT RM910952A1
Authority
IT
Italy
Prior art keywords
pct
compositions containing
gonadotropine
pharmaceutical compositions
sec
Prior art date
Application number
IT000952A
Other languages
English (en)
Inventor
Patrizia Natale
Fabrizio Samaritani
Original Assignee
Serono Cesare Ist Ricerca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Cesare Ist Ricerca filed Critical Serono Cesare Ist Ricerca
Publication of ITRM910952A0 publication Critical patent/ITRM910952A0/it
Priority to ITRM910952A priority Critical patent/IT1250075B/it
Priority to DK93901557T priority patent/DK0618808T3/da
Priority to JP51077493A priority patent/JP3702313B2/ja
Priority to DE69230672T priority patent/DE69230672T2/de
Priority to PT93901557T priority patent/PT618808E/pt
Priority to US08/244,575 priority patent/US5650390A/en
Priority to PCT/IT1992/000165 priority patent/WO1993011788A1/en
Priority to EP93901557A priority patent/EP0618808B1/en
Priority to CA002124801A priority patent/CA2124801C/en
Priority to ES93901557T priority patent/ES2142860T3/es
Priority to AT93901557T priority patent/ATE189608T1/de
Priority to AU32662/93A priority patent/AU677773B2/en
Publication of ITRM910952A1 publication Critical patent/ITRM910952A1/it
Application granted granted Critical
Publication of IT1250075B publication Critical patent/IT1250075B/it
Priority to GR20000400959T priority patent/GR3033276T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
ITRM910952A 1991-12-18 1991-12-18 Composizioni farmaceutiche contenenti gonadotropine. IT1250075B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ITRM910952A IT1250075B (it) 1991-12-18 1991-12-18 Composizioni farmaceutiche contenenti gonadotropine.
PCT/IT1992/000165 WO1993011788A1 (en) 1991-12-18 1992-12-17 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer
CA002124801A CA2124801C (en) 1991-12-18 1992-12-17 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer
DE69230672T DE69230672T2 (de) 1991-12-18 1992-12-17 Gonadotropin, das pharmazeutische zusammensetzungen mit sucrose stabilisator enthält
PT93901557T PT618808E (pt) 1991-12-18 1992-12-17 Composicoes farmaceuticas contendo gonadotrofina com estabilizador de sacarose
US08/244,575 US5650390A (en) 1991-12-18 1992-12-17 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer
DK93901557T DK0618808T3 (da) 1991-12-18 1992-12-17 Farmaceutiske præparater der indeholder gonadotropin med saccharosestabilisator
EP93901557A EP0618808B1 (en) 1991-12-18 1992-12-17 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer
JP51077493A JP3702313B2 (ja) 1991-12-18 1992-12-17 ゴナドトロピン含有薬剤組成物
ES93901557T ES2142860T3 (es) 1991-12-18 1992-12-17 Composiciones farmaceuticas que contienen gonadotropina, con estabilizador de sacarosa.
AT93901557T ATE189608T1 (de) 1991-12-18 1992-12-17 Gonadotropin, das pharmazeutische zusammensetzungen mit sucrose stabilisator enthält
AU32662/93A AU677773B2 (en) 1991-12-18 1992-12-17 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer
GR20000400959T GR3033276T3 (en) 1991-12-18 2000-04-19 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM910952A IT1250075B (it) 1991-12-18 1991-12-18 Composizioni farmaceutiche contenenti gonadotropine.

Publications (3)

Publication Number Publication Date
ITRM910952A0 ITRM910952A0 (it) 1991-12-18
ITRM910952A1 true ITRM910952A1 (it) 1993-06-18
IT1250075B IT1250075B (it) 1995-03-30

Family

ID=11400511

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM910952A IT1250075B (it) 1991-12-18 1991-12-18 Composizioni farmaceutiche contenenti gonadotropine.

Country Status (13)

Country Link
US (1) US5650390A (it)
EP (1) EP0618808B1 (it)
JP (1) JP3702313B2 (it)
AT (1) ATE189608T1 (it)
AU (1) AU677773B2 (it)
CA (1) CA2124801C (it)
DE (1) DE69230672T2 (it)
DK (1) DK0618808T3 (it)
ES (1) ES2142860T3 (it)
GR (1) GR3033276T3 (it)
IT (1) IT1250075B (it)
PT (1) PT618808E (it)
WO (1) WO1993011788A1 (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5828979A (en) * 1994-09-01 1998-10-27 Harris Corporation Automatic train control system and method
EP0814841B1 (en) * 1995-03-21 2001-12-05 Applied Research Systems ARS Holding N.V. Hcg liquid formulations
US6319504B1 (en) 1996-06-24 2001-11-20 University Of Maryland Biotechnology Institute Treatment and prevention of HIV infection by administration of derivatives of human chorionic gonadotropin
IT1284876B1 (it) * 1996-08-07 1998-05-22 Applied Research Systems Hcg come inibitore della collagenasi
IL122732A0 (en) * 1997-01-15 1998-08-16 Akzo Nobel Nv Liquid gonadotropin-containing formulation its preparation and a device containing same
US20030166525A1 (en) 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
AU776823B2 (en) * 1998-07-23 2004-09-23 Ares Trading S.A. FSH and FSH variant formulations, products and methods
JP2002541213A (ja) 1999-04-13 2002-12-03 インヘール セラピューティック システムズ， インコーポレイテッド 不妊症の処置のための乾燥粉末処方物の肺投与
EA006605B1 (ru) * 2000-02-22 2006-02-24 Апплайд Резеч Системз Арс Холдинг Н.В. СПОСОБ ОЧИСТКИ РЕКОМБИНАНТНОГО чХГ
EA004385B1 (ru) * 2000-02-22 2004-04-29 Апплайд Резеч Системз Арс Холдинг Н.В. Способ выделения лютеинизирующего гормона
GB0121709D0 (en) * 2001-09-07 2001-10-31 Imp College Innovations Ltd Food inhibition agent
KR20040032953A (ko) * 2001-09-12 2004-04-17 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. 과배란 유도에서 ｌｈ의 용도
WO2003066585A2 (en) * 2002-02-08 2003-08-14 Alkermes Controlled Therapeutics, Inc. Polymer-based compositions for sustained release
DK1610822T4 (en) * 2003-04-02 2019-01-14 Ares Trading Sa Liquid pharmaceutical FSH and LH formulations together with a nonionic surfactant
CA2526099C (en) * 2003-06-20 2013-02-05 Ares Trading Sa Freeze-dried fsh / lh formulations
KR101105871B1 (ko) * 2005-09-27 2012-01-16 주식회사 엘지생명과학 인 난포자극호르몬의 안정한 용액 제형
JP5551601B2 (ja) * 2007-11-01 2014-07-16 メルク セローノ ソシエテ アノニム Ｌｈ液体調製物
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
CN102309747B (zh) * 2008-09-17 2013-04-17 上海天伟生物制药有限公司 高纯度绝经期促性腺素冻干针剂
KR101483165B1 (ko) * 2009-12-22 2015-01-15 샹하이 테크웰 바이오파마슈티컬 컴퍼니, 리미티드 인간폐경성선자극호르몬의 조성물
JP6426410B2 (ja) * 2013-09-11 2018-11-21 第一三共株式会社 室温保存用凍結乾燥製剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637640A (en) * 1970-05-04 1972-01-25 Diagnostic Data Inc Orgotein stabilized with saccharide process and products
US3816617A (en) * 1972-07-25 1974-06-11 American Home Prod Method for inducing menses
DD141996A1 (de) * 1979-02-21 1980-06-04 Ingrid Wolf Verfahren zur herstellung von lyophilisierten lhrh-praeparationen
JPS59109862A (ja) * 1982-12-15 1984-06-25 Takeda Chem Ind Ltd 凍結乾燥感作血球の製造法
EP0578328B1 (en) * 1983-11-02 1999-12-29 Applied Research Systems ARS Holding N.V. Material and methods for the production of a heterodimeric human LH with a Met42 Val55 alpha subunit
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
IT1206302B (it) * 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US5215743A (en) * 1988-04-13 1993-06-01 Maninder Singh Tumor necrosis factor formulations
WO1989010407A1 (en) * 1988-04-29 1989-11-02 Genetics Institute, Inc. Homogeneous dimeric m-csf and storage stable formulations thereof
JPH02121933A (ja) * 1988-10-28 1990-05-09 Kagaku Shiryo Kenkyusho:Kk 動物用油性ホルモン顆粒剤
US5087615A (en) * 1989-03-17 1992-02-11 Applied Research Systems Ars Holding N.V. Novel method of ovulation induction in humans
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations

Also Published As

Publication number Publication date
US5650390A (en) 1997-07-22
DE69230672T2 (de) 2000-09-21
JPH07507047A (ja) 1995-08-03
EP0618808B1 (en) 2000-02-09
GR3033276T3 (en) 2000-09-29
EP0618808A1 (en) 1994-10-12
ES2142860T3 (es) 2000-05-01
PT618808E (pt) 2000-07-31
AU677773B2 (en) 1997-05-08
CA2124801A1 (en) 1993-06-24
JP3702313B2 (ja) 2005-10-05
ITRM910952A0 (it) 1991-12-18
WO1993011788A1 (en) 1993-06-24
CA2124801C (en) 2007-08-07
DK0618808T3 (da) 2000-05-15
IT1250075B (it) 1995-03-30
DE69230672D1 (de) 2000-03-16
ATE189608T1 (de) 2000-02-15
AU3266293A (en) 1993-07-19

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961217