ATE189608T1 - Gonadotropin, das pharmazeutische zusammensetzungen mit sucrose stabilisator enthält - Google Patents

Gonadotropin, das pharmazeutische zusammensetzungen mit sucrose stabilisator enthält

Info

Publication number
ATE189608T1
ATE189608T1 AT93901557T AT93901557T ATE189608T1 AT E189608 T1 ATE189608 T1 AT E189608T1 AT 93901557 T AT93901557 T AT 93901557T AT 93901557 T AT93901557 T AT 93901557T AT E189608 T1 ATE189608 T1 AT E189608T1
Authority
AT
Austria
Prior art keywords
pct
pharmaceutical compositions
containing pharmaceutical
sucrose
gonadotropin containing
Prior art date
Application number
AT93901557T
Other languages
English (en)
Inventor
Fabrizio Samaritani
Patrizia Natale
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE189608T1 publication Critical patent/ATE189608T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT93901557T 1991-12-18 1992-12-17 Gonadotropin, das pharmazeutische zusammensetzungen mit sucrose stabilisator enthält ATE189608T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM910952A IT1250075B (it) 1991-12-18 1991-12-18 Composizioni farmaceutiche contenenti gonadotropine.
PCT/IT1992/000165 WO1993011788A1 (en) 1991-12-18 1992-12-17 Gonadotropin containing pharmaceutical compositions with sucrose stabilizer

Publications (1)

Publication Number Publication Date
ATE189608T1 true ATE189608T1 (de) 2000-02-15

Family

ID=11400511

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93901557T ATE189608T1 (de) 1991-12-18 1992-12-17 Gonadotropin, das pharmazeutische zusammensetzungen mit sucrose stabilisator enthält

Country Status (13)

Country Link
US (1) US5650390A (de)
EP (1) EP0618808B1 (de)
JP (1) JP3702313B2 (de)
AT (1) ATE189608T1 (de)
AU (1) AU677773B2 (de)
CA (1) CA2124801C (de)
DE (1) DE69230672T2 (de)
DK (1) DK0618808T3 (de)
ES (1) ES2142860T3 (de)
GR (1) GR3033276T3 (de)
IT (1) IT1250075B (de)
PT (1) PT618808E (de)
WO (1) WO1993011788A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5828979A (en) * 1994-09-01 1998-10-27 Harris Corporation Automatic train control system and method
KR100377967B1 (ko) * 1995-03-21 2003-06-12 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. Hcg액상조성물
US6319504B1 (en) 1996-06-24 2001-11-20 University Of Maryland Biotechnology Institute Treatment and prevention of HIV infection by administration of derivatives of human chorionic gonadotropin
IT1284876B1 (it) 1996-08-07 1998-05-22 Applied Research Systems Hcg come inibitore della collagenasi
IL122732A0 (en) * 1997-01-15 1998-08-16 Akzo Nobel Nv Liquid gonadotropin-containing formulation its preparation and a device containing same
AU776823B2 (en) * 1998-07-23 2004-09-23 Ares Trading S.A. FSH and FSH variant formulations, products and methods
US20030166525A1 (en) * 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
US7112341B1 (en) 1999-04-13 2006-09-26 Nektar Therapeutics Pulmonary administration of dry powder formulations for treating infertility
SK287041B6 (sk) * 2000-02-22 2009-10-07 Laboratoires Serono Sa Spôsob čistenia luteinizačného hormónu - LH zo vzorky, rekombinantný hLH, jeho použitie a farmaceutický prostriedok s jeho obsahom
SK287146B6 (sk) * 2000-02-22 2010-01-07 Laboratoires Serono Sa Spôsob prípravy rekombinantného choriogonadotropínu - hCG zo vzorky
GB0121709D0 (en) * 2001-09-07 2001-10-31 Imp College Innovations Ltd Food inhibition agent
MEP38808A (en) * 2001-09-12 2011-02-10 Merck Serono Sa Use of lh in controlled ovarian hyperstimulation
NZ535008A (en) * 2002-02-08 2005-09-30 Alkermes Inc Polymer-based compositions for sustained release
PT1610822E (pt) 2003-04-02 2011-01-05 Ares Trading Sa Formulações farmacêuticas líquidas ou liofilizadas de fsh e/ou lh em conjunto com o surfactante não iónico poloxâmero 188 e um agente bacteriostático
US7740884B2 (en) * 2003-06-20 2010-06-22 Ares Trading S.A. Freeze-dried FSH/LH formulations
KR101105871B1 (ko) * 2005-09-27 2012-01-16 주식회사 엘지생명과학 인 난포자극호르몬의 안정한 용액 제형
DK2219607T3 (da) * 2007-11-01 2013-06-17 Merck Serono Sa Flydende LH-formuleringer
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
CN102309747B (zh) * 2008-09-17 2013-04-17 上海天伟生物制药有限公司 高纯度绝经期促性腺素冻干针剂
CN102100908B (zh) * 2009-12-22 2013-05-08 上海天伟生物制药有限公司 一种蛋白质组合物
JP6426410B2 (ja) * 2013-09-11 2018-11-21 第一三共株式会社 室温保存用凍結乾燥製剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637640A (en) * 1970-05-04 1972-01-25 Diagnostic Data Inc Orgotein stabilized with saccharide process and products
US3816617A (en) * 1972-07-25 1974-06-11 American Home Prod Method for inducing menses
DD141996A1 (de) * 1979-02-21 1980-06-04 Ingrid Wolf Verfahren zur herstellung von lyophilisierten lhrh-praeparationen
JPS59109862A (ja) * 1982-12-15 1984-06-25 Takeda Chem Ind Ltd 凍結乾燥感作血球の製造法
WO1985001959A1 (en) * 1983-11-02 1985-05-09 Integrated Genetics, Inc. Production of heterodimeric human fertlity hormones
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
IT1206302B (it) * 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US5215743A (en) * 1988-04-13 1993-06-01 Maninder Singh Tumor necrosis factor formulations
WO1989010407A1 (en) * 1988-04-29 1989-11-02 Genetics Institute, Inc. Homogeneous dimeric m-csf and storage stable formulations thereof
JPH02121933A (ja) * 1988-10-28 1990-05-09 Kagaku Shiryo Kenkyusho:Kk 動物用油性ホルモン顆粒剤
US5087615A (en) * 1989-03-17 1992-02-11 Applied Research Systems Ars Holding N.V. Novel method of ovulation induction in humans
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations

Also Published As

Publication number Publication date
DK0618808T3 (da) 2000-05-15
JP3702313B2 (ja) 2005-10-05
WO1993011788A1 (en) 1993-06-24
DE69230672T2 (de) 2000-09-21
IT1250075B (it) 1995-03-30
CA2124801C (en) 2007-08-07
JPH07507047A (ja) 1995-08-03
ITRM910952A1 (it) 1993-06-18
DE69230672D1 (de) 2000-03-16
GR3033276T3 (en) 2000-09-29
ITRM910952A0 (it) 1991-12-18
PT618808E (pt) 2000-07-31
EP0618808B1 (de) 2000-02-09
ES2142860T3 (es) 2000-05-01
CA2124801A1 (en) 1993-06-24
US5650390A (en) 1997-07-22
AU677773B2 (en) 1997-05-08
AU3266293A (en) 1993-07-19
EP0618808A1 (de) 1994-10-12

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Legal Events

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UEP Publication of translation of european patent specification
EEFA Change of the company name