DK0600762T3 - 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse - Google Patents

15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse

Info

Publication number
DK0600762T3
DK0600762T3 DK93402795.4T DK93402795T DK0600762T3 DK 0600762 T3 DK0600762 T3 DK 0600762T3 DK 93402795 T DK93402795 T DK 93402795T DK 0600762 T3 DK0600762 T3 DK 0600762T3
Authority
DK
Denmark
Prior art keywords
deoxypergualin
analogs
processes
preparation
therapeutic use
Prior art date
Application number
DK93402795.4T
Other languages
Danish (da)
English (en)
Inventor
Soth Samreth
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Application granted granted Critical
Publication of DK0600762T3 publication Critical patent/DK0600762T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93402795.4T 1992-12-02 1993-11-17 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse DK0600762T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
DK0600762T3 true DK0600762T3 (da) 1996-11-11

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93402795.4T DK0600762T3 (da) 1992-12-02 1993-11-17 15-deoxyspergualinanaloger, fremgangsmåde til fremstilling deraf og deres terapeutiske anvendelse

Country Status (24)

Country Link
US (1) US5476870A (zh)
EP (1) EP0600762B1 (zh)
JP (1) JP2945261B2 (zh)
KR (1) KR100187328B1 (zh)
CN (1) CN1045431C (zh)
AT (1) ATE140215T1 (zh)
AU (1) AU664124B2 (zh)
CA (1) CA2110437C (zh)
CZ (1) CZ284958B6 (zh)
DE (1) DE69303583T2 (zh)
DK (1) DK0600762T3 (zh)
ES (1) ES2092263T3 (zh)
FI (1) FI112211B (zh)
FR (1) FR2698628B1 (zh)
GR (1) GR3021269T3 (zh)
HK (1) HK1000467A1 (zh)
HU (1) HU218908B (zh)
NO (1) NO180483C (zh)
NZ (1) NZ250330A (zh)
RU (1) RU2114823C1 (zh)
SK (1) SK280286B6 (zh)
TW (1) TW311132B (zh)
UA (1) UA39920C2 (zh)
ZA (1) ZA938821B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2187281A1 (en) * 1995-02-10 1996-08-15 Luc Lebreton 15-deoxyspergualin analogs, their use in therapeutics and their method of preparation
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
EP1107998B1 (en) * 1998-08-28 2004-02-04 Gryphon Sciences Method for the preparation of polyamide chains of precise length, their conjugates with proteins
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
JP5166022B2 (ja) * 2004-05-05 2013-03-21 サイレンス・セラピューティクス・アーゲー 脂質、脂質複合体、およびその使用
KR101366482B1 (ko) 2004-12-27 2014-02-21 사일런스 테라퓨틱스 아게 코팅된 지질 복합체 및 이들의 용도
WO2010074591A1 (ru) 2008-12-24 2010-07-01 Закрытое Акционерное Общество "Beptekc" Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
JP5878172B2 (ja) * 2010-07-29 2016-03-08 ラボラトワール フルニエ エスアーエス 炎症性眼疾患の治療／予防用化合物
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
ES2039213T3 (es) * 1986-04-04 1993-09-16 Microbial Chemistry Research Foundation Procedimiento para producir nuevos compuestos relacionados con espergualina.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
FI935318A (fi) 1994-06-03
CN1045431C (zh) 1999-10-06
FR2698628A1 (fr) 1994-06-03
FI935318A0 (fi) 1993-11-29
EP0600762A1 (fr) 1994-06-08
CA2110437A1 (en) 1994-06-03
ES2092263T3 (es) 1996-11-16
ZA938821B (en) 1994-06-30
TW311132B (zh) 1997-07-21
DE69303583D1 (de) 1996-08-14
HU9303406D0 (en) 1994-03-28
CZ284958B6 (cs) 1999-04-14
GR3021269T3 (en) 1997-01-31
AU5188393A (en) 1994-06-16
NO934338L (no) 1994-06-03
CN1095709A (zh) 1994-11-30
AU664124B2 (en) 1995-11-02
SK280286B6 (sk) 1999-11-08
HUT65782A (en) 1994-07-28
DE69303583T2 (de) 1996-11-21
JPH06293728A (ja) 1994-10-21
ATE140215T1 (de) 1996-07-15
US5476870A (en) 1995-12-19
CA2110437C (en) 1999-04-13
FR2698628B1 (fr) 1995-02-17
FI112211B (fi) 2003-11-14
RU2114823C1 (ru) 1998-07-10
NO180483C (no) 1997-04-30
EP0600762B1 (fr) 1996-07-10
KR940014435A (ko) 1994-07-18
CZ262293A3 (en) 1994-06-15
SK135793A3 (en) 1994-06-08
HK1000467A1 (en) 1998-03-27
KR100187328B1 (ko) 1999-05-15
HU218908B (hu) 2000-12-28
NO180483B (no) 1997-01-20
UA39920C2 (uk) 2001-07-16
JP2945261B2 (ja) 1999-09-06
NZ250330A (en) 1995-06-27
NO934338D0 (no) 1993-11-30

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