DK0533483T3 - Fremgangsmåde til fremstilling af chlorsulfat og sulfamatderivater af 2,3:4,5-bis-O-(q-methylethyliden-beta-D-fruktopyranos - Google Patents

Fremgangsmåde til fremstilling af chlorsulfat og sulfamatderivater af 2,3:4,5-bis-O-(q-methylethyliden-beta-D-fruktopyranos

Info

Publication number
DK0533483T3
DK0533483T3 DK92308509T DK92308509T DK0533483T3 DK 0533483 T3 DK0533483 T3 DK 0533483T3 DK 92308509 T DK92308509 T DK 92308509T DK 92308509 T DK92308509 T DK 92308509T DK 0533483 T3 DK0533483 T3 DK 0533483T3
Authority
DK
Denmark
Prior art keywords
chlorosulfate
fructopyranose
methylethylidene
beta
bis
Prior art date
Application number
DK92308509T
Other languages
Danish (da)
English (en)
Inventor
Cynthia A Maryanoff
Kirk L Sorgi
Lorraine Scott
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Application granted granted Critical
Publication of DK0533483T3 publication Critical patent/DK0533483T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/34—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfuric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK92308509T 1991-09-19 1992-09-18 Fremgangsmåde til fremstilling af chlorsulfat og sulfamatderivater af 2,3:4,5-bis-O-(q-methylethyliden-beta-D-fruktopyranos DK0533483T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76272091A 1991-09-19 1991-09-19
US92626992A 1992-08-05 1992-08-05

Publications (1)

Publication Number Publication Date
DK0533483T3 true DK0533483T3 (da) 1998-09-28

Family

ID=27117178

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92308509T DK0533483T3 (da) 1991-09-19 1992-09-18 Fremgangsmåde til fremstilling af chlorsulfat og sulfamatderivater af 2,3:4,5-bis-O-(q-methylethyliden-beta-D-fruktopyranos

Country Status (23)

Country Link
US (1) US5387700A (de)
EP (1) EP0533483B1 (de)
JP (1) JP3174410B2 (de)
KR (1) KR100229180B1 (de)
CN (1) CN1035820C (de)
AT (1) ATE163937T1 (de)
AU (1) AU651244B2 (de)
CA (1) CA2078519C (de)
DE (1) DE69224691T2 (de)
DK (1) DK0533483T3 (de)
EG (1) EG20164A (de)
ES (1) ES2114917T3 (de)
FI (1) FI107731B (de)
GR (1) GR3026618T3 (de)
HU (1) HU212634B (de)
IL (1) IL103172A (de)
MX (1) MX9205305A (de)
MY (1) MY113564A (de)
NO (1) NO179284C (de)
NZ (1) NZ244409A (de)
PH (1) PH31291A (de)
TW (1) TW217413B (de)
ZW (1) ZW14792A1 (de)

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MXPA03003870A (es) * 2000-10-30 2004-08-12 Johnson & Johnson Terapia de combinacion que comprende agentes antidiabeticos y anticonvulsionantes.
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US7060725B2 (en) * 2002-05-13 2006-06-13 Janssen Pharmaceutica N.V. Substituted sulfamate anticonvulsant derivatives
US20040115262A1 (en) * 2002-07-29 2004-06-17 Frank Jao Formulations and dosage forms for controlled delivery of topiramate
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
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US7196209B2 (en) * 2002-10-31 2007-03-27 Ortho-Mcneil Pharmaceutical, Inc. Continuous process for the preparation of fructopyranose sulfamate derivatives
UA81657C2 (ru) * 2003-03-04 2008-01-25 Орто-Макнейл Фармасьютикел, Инк. Способ получения противосудорожных производных топирамата
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AU2004264316A1 (en) * 2003-08-06 2005-02-24 Alza Corporation Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation
JP2007503389A (ja) * 2003-08-22 2007-02-22 アルザ・コーポレーシヨン 長期間にわたるトピラメートの段階的送達
EP1701697A2 (de) * 2003-09-02 2006-09-20 ALZA Corporation Neue arzneimittelzusammensetzungen und dosierformen von topiramat
KR20060120193A (ko) * 2003-11-14 2006-11-24 알자 코포레이션 액체 제형내 토피라메이트의 제어된 방출
KR20050062976A (ko) * 2003-12-19 2005-06-28 일동제약주식회사 2,3:4,5-비스-오-(1-메틸에틸리덴)-베타-디-프럭토피라노즈설파메이트의 새로운 개량된 제조방법
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
WO2005065648A2 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc., Novel drug compositions and dosage forms of topiramate
MXPA06007509A (es) * 2003-12-29 2007-10-18 Johnson & Johnson Composiciones de farmaco y formas de dosis novedosas.
US20050203287A1 (en) * 2004-03-11 2005-09-15 Chandrasekhar Batchu Process for the preparation of sulfamate derivatives
MY147767A (en) * 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
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US20070155827A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
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US20070191449A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Depression
US20070191461A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine
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US20070191474A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine
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JP5424571B2 (ja) * 2007-04-12 2014-02-26 協和発酵キリン株式会社 トピラマート含有固形製剤
CN101720397B (zh) * 2007-04-24 2013-01-02 福博科技术公司 电力牵引传动装置
CN101450951B (zh) * 2007-11-30 2012-10-10 重庆凯林制药有限公司 托吡酯的制备方法
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
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CN102936268A (zh) * 2012-11-13 2013-02-20 江苏吉贝尔药业有限公司 一种托吡酯中间体丙酮叉的制备方法
CN106397502A (zh) * 2016-08-31 2017-02-15 安徽省润生医药股份有限公司 一种托吡酯的合成工艺
CN108341844A (zh) * 2018-04-25 2018-07-31 广州小桔生物科技有限公司 一种高纯度托吡酯的制备方法
CN110655541A (zh) * 2018-06-29 2020-01-07 鲁南制药集团股份有限公司 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯晶型
CN110655542A (zh) * 2018-06-29 2020-01-07 鲁南制药集团股份有限公司 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯的晶型
EP3883546A1 (de) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Orale topiramat-suspensionsformulierungen mit verlängerter lagerstabilität und verbesserter bioverfügbarkeit
CN114350340B (zh) * 2022-01-13 2023-01-17 陕西科技大学 一种压裂用增渗剂及其制备方法和应用

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Also Published As

Publication number Publication date
PH31291A (en) 1998-07-06
NO923637D0 (no) 1992-09-18
ES2114917T3 (es) 1998-06-16
IL103172A (en) 1997-01-10
HUT63612A (en) 1993-09-28
KR100229180B1 (ko) 1999-11-01
DE69224691D1 (de) 1998-04-16
ATE163937T1 (de) 1998-03-15
EP0533483A2 (de) 1993-03-24
CA2078519A1 (en) 1993-03-20
US5387700A (en) 1995-02-07
ZW14792A1 (en) 1994-04-20
MY113564A (en) 2002-04-30
DE69224691T2 (de) 1998-08-20
FI924189A0 (fi) 1992-09-18
CA2078519C (en) 2003-09-16
TW217413B (de) 1993-12-11
FI924189A (fi) 1993-03-20
NO179284C (no) 1996-09-11
HU9202974D0 (en) 1992-11-30
GR3026618T3 (en) 1998-07-31
FI107731B (fi) 2001-09-28
EP0533483B1 (de) 1998-03-11
AU2451892A (en) 1993-03-25
NZ244409A (en) 1995-02-24
CN1075317A (zh) 1993-08-18
EP0533483A3 (en) 1994-11-02
EG20164A (en) 1997-08-31
NO179284B (no) 1996-06-03
CN1035820C (zh) 1997-09-10
KR930006029A (ko) 1993-04-20
MX9205305A (es) 1993-07-01
IL103172A0 (en) 1993-02-21
NO923637L (no) 1993-03-22
HU212634B (en) 1996-09-30
JPH05230011A (ja) 1993-09-07
AU651244B2 (en) 1994-07-14
JP3174410B2 (ja) 2001-06-11

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