FI924189A0 - Foerfarande foer framstaellning av klorsulfat- och sulfamatderivat av 2,3:4,5-bis-0-(1-metyletyliden)-b-d -fruktopyranos och (1-metylcyclohexyl) etanol. - Google Patents

Foerfarande foer framstaellning av klorsulfat- och sulfamatderivat av 2,3:4,5-bis-0-(1-metyletyliden)-b-d -fruktopyranos och (1-metylcyclohexyl) etanol.

Info

Publication number
FI924189A0
FI924189A0 FI924189A FI924189A FI924189A0 FI 924189 A0 FI924189 A0 FI 924189A0 FI 924189 A FI924189 A FI 924189A FI 924189 A FI924189 A FI 924189A FI 924189 A0 FI924189 A0 FI 924189A0
Authority
FI
Finland
Prior art keywords
fructopyranose
methylcyclohexyl
bis
sulfamaters
methylthyliden
Prior art date
Application number
FI924189A
Other languages
English (en)
Other versions
FI107731B (fi
FI924189A (fi
Inventor
Cynthia A Maryanoff
Lorraine Scott
Kirk L Sorgi
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of FI924189A0 publication Critical patent/FI924189A0/fi
Publication of FI924189A publication Critical patent/FI924189A/fi
Application granted granted Critical
Publication of FI107731B publication Critical patent/FI107731B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/34—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfuric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI924189A 1991-09-19 1992-09-18 Menetelmä 2,3:4,5-bis-O-(1-metyylietylideeni)-beta-D-fruktopyranoosin ja (1-metyylisykloheksyyli)metanolin kloorisulfaatti- ja sulfamaattijohdannaisten valmistamiseksi FI107731B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76272091A 1991-09-19 1991-09-19
US76272091 1991-09-19
US92626992A 1992-08-05 1992-08-05
US92626992 1992-08-05

Publications (3)

Publication Number Publication Date
FI924189A0 true FI924189A0 (fi) 1992-09-18
FI924189A FI924189A (fi) 1993-03-20
FI107731B FI107731B (fi) 2001-09-28

Family

ID=27117178

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924189A FI107731B (fi) 1991-09-19 1992-09-18 Menetelmä 2,3:4,5-bis-O-(1-metyylietylideeni)-beta-D-fruktopyranoosin ja (1-metyylisykloheksyyli)metanolin kloorisulfaatti- ja sulfamaattijohdannaisten valmistamiseksi

Country Status (23)

Country Link
US (1) US5387700A (fi)
EP (1) EP0533483B1 (fi)
JP (1) JP3174410B2 (fi)
KR (1) KR100229180B1 (fi)
CN (1) CN1035820C (fi)
AT (1) ATE163937T1 (fi)
AU (1) AU651244B2 (fi)
CA (1) CA2078519C (fi)
DE (1) DE69224691T2 (fi)
DK (1) DK0533483T3 (fi)
EG (1) EG20164A (fi)
ES (1) ES2114917T3 (fi)
FI (1) FI107731B (fi)
GR (1) GR3026618T3 (fi)
HU (1) HU212634B (fi)
IL (1) IL103172A (fi)
MX (1) MX9205305A (fi)
MY (1) MY113564A (fi)
NO (1) NO179284C (fi)
NZ (1) NZ244409A (fi)
PH (1) PH31291A (fi)
TW (1) TW217413B (fi)
ZW (1) ZW14792A1 (fi)

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US7041650B2 (en) * 2001-07-09 2006-05-09 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivative salts
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AU2003213719A1 (en) 2002-03-01 2003-09-16 Regents Of The University Of Michigan Multiple-component solid phases containing at least one active pharmaceutical ingredient
US7060725B2 (en) * 2002-05-13 2006-06-13 Janssen Pharmaceutica N.V. Substituted sulfamate anticonvulsant derivatives
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
WO2004010970A1 (en) * 2002-07-29 2004-02-05 Alza Corporation Formulations and dosage forms for controlled delivery of topiramate
UA80450C2 (en) * 2002-10-31 2007-09-25 Ortho Mcneil Pharm Inc Continuous process for the preparation of fructopyranose sulfamate derivatives
US7196209B2 (en) * 2002-10-31 2007-03-27 Ortho-Mcneil Pharmaceutical, Inc. Continuous process for the preparation of fructopyranose sulfamate derivatives
UA81657C2 (ru) * 2003-03-04 2008-01-25 Орто-Макнейл Фармасьютикел, Инк. Способ получения противосудорожных производных топирамата
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TW200528144A (en) * 2003-11-14 2005-09-01 Alza Corp Controlled release of topiramate in liquid dosage forms
KR20050062976A (ko) * 2003-12-19 2005-06-28 일동제약주식회사 2,3:4,5-비스-오-(1-메틸에틸리덴)-베타-디-프럭토피라노즈설파메이트의 새로운 개량된 제조방법
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
CA2551815A1 (en) * 2003-12-29 2005-07-21 Alza Corporation Novel drug compositions and dosage forms
CA2550699A1 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc. Novel drug compositions and dosage forms of topiramate
US20050203287A1 (en) * 2004-03-11 2005-09-15 Chandrasekhar Batchu Process for the preparation of sulfamate derivatives
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AU2005277134A1 (en) * 2004-08-24 2006-03-02 Janssen Pharmaceutica N.V. Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents
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US8497298B2 (en) * 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8716231B2 (en) * 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US20070191474A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine
US20070191449A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Depression
US20070191453A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of substance abuse and addiction
US20070191461A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine
US20070191459A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of Benzo-Heteroaryl Sulfamide Derivatives for Lowering Lipids and Lowering Blood Glucose Levels
WO2007099388A1 (en) * 2006-03-01 2007-09-07 Glade Organics Private Limited An improved process for the manufacture of topiramate
WO2007108009A1 (en) * 2006-03-17 2007-09-27 Alembic Limited A process for purification of topiramate
AU2007253814A1 (en) * 2006-05-19 2007-11-29 Janssen Pharmaceutica N.V. Co-therapy for the treatment of epilepsy
JP5424571B2 (ja) * 2007-04-12 2014-02-26 協和発酵キリン株式会社 トピラマート含有固形製剤
EP2573424A3 (en) * 2007-04-24 2017-07-26 Fallbrook Intellectual Property Company LLC Electric traction drives
CN101450951B (zh) * 2007-11-30 2012-10-10 重庆凯林制药有限公司 托吡酯的制备方法
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
US20090247616A1 (en) * 2008-03-26 2009-10-01 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety
AU2009271362B2 (en) 2008-06-23 2014-03-13 Janssen Pharmaceutica Nv Crystalline form of (2s)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide
US8815939B2 (en) * 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
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CN102936268A (zh) * 2012-11-13 2013-02-20 江苏吉贝尔药业有限公司 一种托吡酯中间体丙酮叉的制备方法
CN106397502A (zh) * 2016-08-31 2017-02-15 安徽省润生医药股份有限公司 一种托吡酯的合成工艺
CN108341844A (zh) * 2018-04-25 2018-07-31 广州小桔生物科技有限公司 一种高纯度托吡酯的制备方法
CN110655541A (zh) * 2018-06-29 2020-01-07 鲁南制药集团股份有限公司 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯晶型
CN110655542A (zh) * 2018-06-29 2020-01-07 鲁南制药集团股份有限公司 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯的晶型
EP3883546A1 (en) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
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Also Published As

Publication number Publication date
NO923637L (no) 1993-03-22
EG20164A (en) 1997-08-31
EP0533483A3 (en) 1994-11-02
GR3026618T3 (en) 1998-07-31
NZ244409A (en) 1995-02-24
CN1075317A (zh) 1993-08-18
CA2078519C (en) 2003-09-16
ATE163937T1 (de) 1998-03-15
JPH05230011A (ja) 1993-09-07
ES2114917T3 (es) 1998-06-16
DE69224691D1 (de) 1998-04-16
TW217413B (fi) 1993-12-11
PH31291A (en) 1998-07-06
ZW14792A1 (en) 1994-04-20
CA2078519A1 (en) 1993-03-20
MX9205305A (es) 1993-07-01
DE69224691T2 (de) 1998-08-20
NO179284B (no) 1996-06-03
KR100229180B1 (ko) 1999-11-01
HUT63612A (en) 1993-09-28
FI107731B (fi) 2001-09-28
MY113564A (en) 2002-04-30
KR930006029A (ko) 1993-04-20
AU651244B2 (en) 1994-07-14
NO923637D0 (no) 1992-09-18
US5387700A (en) 1995-02-07
CN1035820C (zh) 1997-09-10
AU2451892A (en) 1993-03-25
IL103172A0 (en) 1993-02-21
HU212634B (en) 1996-09-30
NO179284C (no) 1996-09-11
JP3174410B2 (ja) 2001-06-11
FI924189A (fi) 1993-03-20
DK0533483T3 (da) 1998-09-28
IL103172A (en) 1997-01-10
EP0533483B1 (en) 1998-03-11
HU9202974D0 (en) 1992-11-30
EP0533483A2 (en) 1993-03-24

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