DK0490183T3 - Benzoxazinon- og benzothiazinonderivater med kardiovaskulær aktivitet - Google Patents

Benzoxazinon- og benzothiazinonderivater med kardiovaskulær aktivitet

Info

Publication number
DK0490183T3
DK0490183T3 DK91120471.7T DK91120471T DK0490183T3 DK 0490183 T3 DK0490183 T3 DK 0490183T3 DK 91120471 T DK91120471 T DK 91120471T DK 0490183 T3 DK0490183 T3 DK 0490183T3
Authority
DK
Denmark
Prior art keywords
benzoxazinone
cardiovascular activity
benzothiazinone derivatives
alkyl
benzothiazinone
Prior art date
Application number
DK91120471.7T
Other languages
English (en)
Inventor
Alberto Sala
Francesca Benedini
Roberta Cereda
Soldato Piero Del
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Application granted granted Critical
Publication of DK0490183T3 publication Critical patent/DK0490183T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK91120471.7T 1990-12-14 1991-11-29 Benzoxazinon- og benzothiazinonderivater med kardiovaskulær aktivitet DK0490183T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02239490A IT1244472B (it) 1990-12-14 1990-12-14 Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare

Publications (1)

Publication Number Publication Date
DK0490183T3 true DK0490183T3 (da) 1995-06-26

Family

ID=11195702

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91120471.7T DK0490183T3 (da) 1990-12-14 1991-11-29 Benzoxazinon- og benzothiazinonderivater med kardiovaskulær aktivitet

Country Status (22)

Country Link
US (1) US5189034A (da)
EP (1) EP0490183B1 (da)
JP (1) JP2512845B2 (da)
KR (1) KR960016124B1 (da)
AT (1) ATE121392T1 (da)
AU (1) AU644254B2 (da)
CA (1) CA2056814C (da)
DE (2) DE490183T1 (da)
DK (1) DK0490183T3 (da)
ES (1) ES2051674T3 (da)
FI (1) FI95796C (da)
GR (2) GR920300088T1 (da)
HU (1) HUT63398A (da)
IE (1) IE67625B1 (da)
IT (1) IT1244472B (da)
LV (1) LV11029B (da)
MX (1) MX9102540A (da)
NO (1) NO180585C (da)
NZ (1) NZ240978A (da)
PT (1) PT99790B (da)
TW (1) TW233296B (da)
ZA (1) ZA919496B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245351B (it) * 1991-03-19 1994-09-20 Italfarmaco Spa Isoindoli ad attivita' cardiovascolare
IT1254884B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare
IT1256023B (it) * 1992-06-10 1995-11-20 Italfarmaco Spa Derivati benzossazinonici e benzotiazinonici ad attivita' cardiovascolare
CH685700A5 (fr) * 1993-03-16 1995-09-15 Cermol Sa Esters nitriques de 1,2-benzo-isothiazolyl-3(2H)one-1,1-dioxyde, procédé de préparation de ces esters et médicaments contenant ces esters.
IT1264812B1 (it) * 1993-07-28 1996-10-10 Italfarmaco Spa Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi
JP4613082B2 (ja) 2005-03-14 2011-01-12 ヤンマー株式会社 作業車両のボンネット構造
US8148368B2 (en) * 2010-09-07 2012-04-03 Shaikh Riazuddin 7-nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections
CN103687843B (zh) * 2011-10-24 2016-11-16 尼科斯科学爱尔兰公司 醌基一氧化氮供体化合物
KR102288434B1 (ko) * 2018-10-18 2021-08-12 에이치케이이노엔 주식회사 신규한 (이소프로필-트리아졸릴)피리디닐 치환된 벤조옥사지논 또는 벤조티아지논 유도체 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459748A (en) * 1967-04-28 1969-08-05 Squibb & Sons Inc Hydroxyalkylene-substituted benzoxazines and benzothiazines
US3513166A (en) * 1967-05-22 1970-05-19 Robins Co Inc A H 3-(omega-aminoalkyl)-4-substituted-1,3-benzoxazine-2-ones
GB1274553A (en) * 1969-05-06 1972-05-17 Squibb & Sons Inc Hydroxyalkylene-substituted benzoxazines and benzothiazines
JPS6137766A (ja) * 1984-07-31 1986-02-22 Sankyo Co Ltd フタルイミド誘導体およびその製造法
FR2636065B1 (fr) * 1988-09-08 1993-05-07 Fabre Sa Pierre Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique

Also Published As

Publication number Publication date
FI95796B (fi) 1995-12-15
JP2512845B2 (ja) 1996-07-03
NO180585B (no) 1997-02-03
AU8972291A (en) 1992-06-18
CA2056814C (en) 1997-01-14
PT99790A (pt) 1992-12-31
DE490183T1 (de) 1992-12-17
NO914938D0 (no) 1991-12-13
ES2051674T1 (es) 1994-07-01
NO914938L (no) 1992-06-15
FI915875A0 (fi) 1991-12-13
KR920012052A (ko) 1992-07-25
HUT63398A (en) 1993-08-30
GR920300088T1 (en) 1992-12-30
PT99790B (pt) 1999-05-31
IT9022394A0 (it) 1990-12-14
JPH0532642A (ja) 1993-02-09
NO180585C (no) 1997-05-14
EP0490183B1 (en) 1995-04-19
CA2056814A1 (en) 1992-06-15
HU913950D0 (en) 1992-02-28
IE67625B1 (en) 1996-04-17
GR3015901T3 (en) 1995-07-31
US5189034A (en) 1993-02-23
IT1244472B (it) 1994-07-15
MX9102540A (es) 1992-06-01
LV11029A (lv) 1996-02-20
DE69109066T2 (de) 1995-09-21
FI915875A (fi) 1992-06-15
ES2051674T3 (es) 1995-06-16
LV11029B (en) 1996-06-20
IT9022394A1 (it) 1992-06-14
NZ240978A (en) 1993-07-27
IE914343A1 (en) 1992-06-17
ATE121392T1 (de) 1995-05-15
AU644254B2 (en) 1993-12-02
DE69109066D1 (de) 1995-05-24
TW233296B (da) 1994-11-01
EP0490183A1 (en) 1992-06-17
FI95796C (fi) 1996-03-25
KR960016124B1 (ko) 1996-12-04
ZA919496B (en) 1992-08-26

Similar Documents

Publication Publication Date Title
DE68920482D1 (de) 1-Indolylalkyl-4-(substituierte Pyridinyl)-Piperazine.
DK0490183T3 (da) Benzoxazinon- og benzothiazinonderivater med kardiovaskulær aktivitet
FI910058A (fi) Fungicider.
FI875643A (fi) Kemiska foereningar och deras anvaendning som braensletillsatser.
NO931225D0 (no) Benzoksazinon- og benzotiazinon-derivater med kardiovaskulaer akrivitet
FI933755A (fi) Foerfarande foer framstaellning av trans-piperidin-2,5-dikarboxylater
NO960308L (no) Terapeutisk aktive benzoksaziner og benzotioanoner