IT1245351B - Isoindoli ad attivita' cardiovascolare - Google Patents
Isoindoli ad attivita' cardiovascolareInfo
- Publication number
- IT1245351B IT1245351B ITMI910732A ITMI910732A IT1245351B IT 1245351 B IT1245351 B IT 1245351B IT MI910732 A ITMI910732 A IT MI910732A IT MI910732 A ITMI910732 A IT MI910732A IT 1245351 B IT1245351 B IT 1245351B
- Authority
- IT
- Italy
- Prior art keywords
- isoindles
- cardiovascular activity
- activity
- cardiovascular
- formula
- Prior art date
Links
- 230000005792 cardiovascular activity Effects 0.000 title 1
- 230000003257 anti-anginal effect Effects 0.000 abstract 1
- 150000002518 isoindoles Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Vengono descritti isoindoli di formula generale: FORMULA 1 e loro sali farmaceuticamente accettabili, un procedimento per la loro preparazione e il loro uso come sostanze dotate di attività antianginosa.
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910732A IT1245351B (it) | 1991-03-19 | 1991-03-19 | Isoindoli ad attivita' cardiovascolare |
JP4505510A JPH06505722A (ja) | 1991-03-19 | 1992-03-11 | 心臓血管活性を有するイソインドール類 |
DE69204995T DE69204995T2 (de) | 1991-03-19 | 1992-03-11 | Isoindole mit cardiovaskulärer aktivität. |
DK92906404.6T DK0576475T3 (da) | 1991-03-19 | 1992-03-11 | Isoindoler med kardiovaskulær aktivitet |
AT92906404T ATE128123T1 (de) | 1991-03-19 | 1992-03-11 | Isoindole mit cardiovaskulärer aktivität. |
AU13479/92A AU659442B2 (en) | 1991-03-19 | 1992-03-11 | Isoindoles having cardiovascular activity |
HU9302507A HUT67668A (en) | 1991-03-19 | 1992-03-11 | Process for producing isoindoles having cardiovascular activity and pharmeceutical compositions comprising them |
ES92906404T ES2079185T3 (es) | 1991-03-19 | 1992-03-11 | Isoindoles con actividad cardiovascular. |
PCT/EP1992/000531 WO1992016506A1 (en) | 1991-03-19 | 1992-03-11 | Isoindoles having cardiovascular activity |
CA002105684A CA2105684A1 (en) | 1991-03-19 | 1992-03-11 | Isoindoles having cardiovascular activity |
EP92906404A EP0576475B1 (en) | 1991-03-19 | 1992-03-11 | Isoindoles having cardiovascular activity |
US08/117,162 US5376673A (en) | 1991-03-19 | 1993-09-17 | Isoindoles having cardiovascular activity |
NO93933324A NO933324L (no) | 1991-03-19 | 1993-09-17 | Isoindoler med kardiovaskulaer aktivitet |
GR950403099T GR3017990T3 (en) | 1991-03-19 | 1995-11-08 | Isoindoles having cardiovascular activity. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910732A IT1245351B (it) | 1991-03-19 | 1991-03-19 | Isoindoli ad attivita' cardiovascolare |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI910732A0 ITMI910732A0 (it) | 1991-03-19 |
ITMI910732A1 ITMI910732A1 (it) | 1992-09-19 |
IT1245351B true IT1245351B (it) | 1994-09-20 |
Family
ID=11359118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI910732A IT1245351B (it) | 1991-03-19 | 1991-03-19 | Isoindoli ad attivita' cardiovascolare |
Country Status (13)
Country | Link |
---|---|
US (1) | US5376673A (it) |
EP (1) | EP0576475B1 (it) |
JP (1) | JPH06505722A (it) |
AT (1) | ATE128123T1 (it) |
AU (1) | AU659442B2 (it) |
CA (1) | CA2105684A1 (it) |
DE (1) | DE69204995T2 (it) |
DK (1) | DK0576475T3 (it) |
ES (1) | ES2079185T3 (it) |
GR (1) | GR3017990T3 (it) |
HU (1) | HUT67668A (it) |
IT (1) | IT1245351B (it) |
WO (1) | WO1992016506A1 (it) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69321596T2 (de) * | 1992-07-30 | 1999-04-22 | Cal International Ltd | Ester und kombinationen von einem organischen nitrat und einem salicyclat |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6137766A (ja) * | 1984-07-31 | 1986-02-22 | Sankyo Co Ltd | フタルイミド誘導体およびその製造法 |
DE3533442A1 (de) * | 1985-09-19 | 1987-03-26 | Hoechst Ag | Neue 2-aryl-4,5,6,7-tetrahydroisoindolinone, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz |
IT1244472B (it) * | 1990-12-14 | 1994-07-15 | Italfarmaco Spa | Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare |
-
1991
- 1991-03-19 IT ITMI910732A patent/IT1245351B/it active IP Right Grant
-
1992
- 1992-03-11 CA CA002105684A patent/CA2105684A1/en not_active Abandoned
- 1992-03-11 AU AU13479/92A patent/AU659442B2/en not_active Ceased
- 1992-03-11 ES ES92906404T patent/ES2079185T3/es not_active Expired - Lifetime
- 1992-03-11 HU HU9302507A patent/HUT67668A/hu unknown
- 1992-03-11 AT AT92906404T patent/ATE128123T1/de not_active IP Right Cessation
- 1992-03-11 JP JP4505510A patent/JPH06505722A/ja active Pending
- 1992-03-11 DK DK92906404.6T patent/DK0576475T3/da active
- 1992-03-11 DE DE69204995T patent/DE69204995T2/de not_active Expired - Fee Related
- 1992-03-11 WO PCT/EP1992/000531 patent/WO1992016506A1/en active IP Right Grant
- 1992-03-11 EP EP92906404A patent/EP0576475B1/en not_active Expired - Lifetime
-
1993
- 1993-09-17 US US08/117,162 patent/US5376673A/en not_active Expired - Fee Related
-
1995
- 1995-11-08 GR GR950403099T patent/GR3017990T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2079185T3 (es) | 1996-01-01 |
HUT67668A (en) | 1995-04-28 |
DK0576475T3 (da) | 1996-01-15 |
HU9302507D0 (en) | 1993-12-28 |
ATE128123T1 (de) | 1995-10-15 |
EP0576475B1 (en) | 1995-09-20 |
GR3017990T3 (en) | 1996-02-29 |
JPH06505722A (ja) | 1994-06-30 |
EP0576475A1 (en) | 1994-01-05 |
ITMI910732A1 (it) | 1992-09-19 |
AU1347992A (en) | 1992-10-21 |
DE69204995D1 (de) | 1995-10-26 |
ITMI910732A0 (it) | 1991-03-19 |
CA2105684A1 (en) | 1992-09-20 |
US5376673A (en) | 1994-12-27 |
DE69204995T2 (de) | 1996-02-08 |
WO1992016506A1 (en) | 1992-10-01 |
AU659442B2 (en) | 1995-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950329 |