IT1245351B - Isoindoli ad attivita' cardiovascolare - Google Patents

Isoindoli ad attivita' cardiovascolare

Info

Publication number
IT1245351B
IT1245351B ITMI910732A ITMI910732A IT1245351B IT 1245351 B IT1245351 B IT 1245351B IT MI910732 A ITMI910732 A IT MI910732A IT MI910732 A ITMI910732 A IT MI910732A IT 1245351 B IT1245351 B IT 1245351B
Authority
IT
Italy
Prior art keywords
isoindles
cardiovascular activity
activity
cardiovascular
formula
Prior art date
Application number
ITMI910732A
Other languages
English (en)
Inventor
Alberto Sala
Silvio Levi
Francesca Benedini
Roberta Cereda
Soldato Piero Del
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of ITMI910732A0 publication Critical patent/ITMI910732A0/it
Priority to ITMI910732A priority Critical patent/IT1245351B/it
Priority to PCT/EP1992/000531 priority patent/WO1992016506A1/en
Priority to JP4505510A priority patent/JPH06505722A/ja
Priority to DE69204995T priority patent/DE69204995T2/de
Priority to HU9302507A priority patent/HUT67668A/hu
Priority to EP92906404A priority patent/EP0576475B1/en
Priority to CA002105684A priority patent/CA2105684A1/en
Priority to AT92906404T priority patent/ATE128123T1/de
Priority to AU13479/92A priority patent/AU659442B2/en
Priority to DK92906404.6T priority patent/DK0576475T3/da
Priority to ES92906404T priority patent/ES2079185T3/es
Publication of ITMI910732A1 publication Critical patent/ITMI910732A1/it
Priority to NO93933324A priority patent/NO933324L/no
Priority to US08/117,162 priority patent/US5376673A/en
Application granted granted Critical
Publication of IT1245351B publication Critical patent/IT1245351B/it
Priority to GR950403099T priority patent/GR3017990T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Vengono descritti isoindoli di formula generale: FORMULA 1 e loro sali farmaceuticamente accettabili, un procedimento per la loro preparazione e il loro uso come sostanze dotate di attività antianginosa.
ITMI910732A 1991-03-19 1991-03-19 Isoindoli ad attivita' cardiovascolare IT1245351B (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
ITMI910732A IT1245351B (it) 1991-03-19 1991-03-19 Isoindoli ad attivita' cardiovascolare
CA002105684A CA2105684A1 (en) 1991-03-19 1992-03-11 Isoindoles having cardiovascular activity
AU13479/92A AU659442B2 (en) 1991-03-19 1992-03-11 Isoindoles having cardiovascular activity
DE69204995T DE69204995T2 (de) 1991-03-19 1992-03-11 Isoindole mit cardiovaskulärer aktivität.
HU9302507A HUT67668A (en) 1991-03-19 1992-03-11 Process for producing isoindoles having cardiovascular activity and pharmeceutical compositions comprising them
EP92906404A EP0576475B1 (en) 1991-03-19 1992-03-11 Isoindoles having cardiovascular activity
PCT/EP1992/000531 WO1992016506A1 (en) 1991-03-19 1992-03-11 Isoindoles having cardiovascular activity
AT92906404T ATE128123T1 (de) 1991-03-19 1992-03-11 Isoindole mit cardiovaskulärer aktivität.
JP4505510A JPH06505722A (ja) 1991-03-19 1992-03-11 心臓血管活性を有するイソインドール類
DK92906404.6T DK0576475T3 (da) 1991-03-19 1992-03-11 Isoindoler med kardiovaskulær aktivitet
ES92906404T ES2079185T3 (es) 1991-03-19 1992-03-11 Isoindoles con actividad cardiovascular.
NO93933324A NO933324L (no) 1991-03-19 1993-09-17 Isoindoler med kardiovaskulaer aktivitet
US08/117,162 US5376673A (en) 1991-03-19 1993-09-17 Isoindoles having cardiovascular activity
GR950403099T GR3017990T3 (en) 1991-03-19 1995-11-08 Isoindoles having cardiovascular activity.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910732A IT1245351B (it) 1991-03-19 1991-03-19 Isoindoli ad attivita' cardiovascolare

Publications (3)

Publication Number Publication Date
ITMI910732A0 ITMI910732A0 (it) 1991-03-19
ITMI910732A1 ITMI910732A1 (it) 1992-09-19
IT1245351B true IT1245351B (it) 1994-09-20

Family

ID=11359118

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI910732A IT1245351B (it) 1991-03-19 1991-03-19 Isoindoli ad attivita' cardiovascolare

Country Status (13)

Country Link
US (1) US5376673A (it)
EP (1) EP0576475B1 (it)
JP (1) JPH06505722A (it)
AT (1) ATE128123T1 (it)
AU (1) AU659442B2 (it)
CA (1) CA2105684A1 (it)
DE (1) DE69204995T2 (it)
DK (1) DK0576475T3 (it)
ES (1) ES2079185T3 (it)
GR (1) GR3017990T3 (it)
HU (1) HUT67668A (it)
IT (1) IT1245351B (it)
WO (1) WO1992016506A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE172183T1 (de) * 1992-07-30 1998-10-15 Cal Int Ltd Ester und kombinationen von einem organischen nitrat und einem salicyclat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6137766A (ja) * 1984-07-31 1986-02-22 Sankyo Co Ltd フタルイミド誘導体およびその製造法
DE3533442A1 (de) * 1985-09-19 1987-03-26 Hoechst Ag Neue 2-aryl-4,5,6,7-tetrahydroisoindolinone, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz
IT1244472B (it) * 1990-12-14 1994-07-15 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare

Also Published As

Publication number Publication date
ITMI910732A0 (it) 1991-03-19
EP0576475A1 (en) 1994-01-05
HU9302507D0 (en) 1993-12-28
CA2105684A1 (en) 1992-09-20
ES2079185T3 (es) 1996-01-01
HUT67668A (en) 1995-04-28
JPH06505722A (ja) 1994-06-30
WO1992016506A1 (en) 1992-10-01
DE69204995D1 (de) 1995-10-26
GR3017990T3 (en) 1996-02-29
ITMI910732A1 (it) 1992-09-19
EP0576475B1 (en) 1995-09-20
AU1347992A (en) 1992-10-21
AU659442B2 (en) 1995-05-18
ATE128123T1 (de) 1995-10-15
DK0576475T3 (da) 1996-01-15
US5376673A (en) 1994-12-27
DE69204995T2 (de) 1996-02-08

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950329